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9023874 Fluorinated oxa or thia heteroarylalkylsulfide derivatives for combating invertebrate pests  
The invention relates to alkylsulfide derivatives compounds of formula I as hereunder depicted or the enantiomers or veterinarily acceptable salts thereof which are useful for combating or...
9006278 Controlled release systems of pluribioactive antifungal drugs and applications thereof  
Controlled release systems release at least one pluribioactive antifungal drug exhibiting at least one additional bioactivity from the group consisting of spermiostatic, antineoplastic,...
9000017 Combinations of imazalil and silver compounds  
The present invention relates to combinations of imazalil, or a salt thereof, and silver compounds which provide an improved biocidal effect. More particularly, the present invention relates to...
9000022 Imidazole based LXR modulators  
Methods of using compounds of the invention, such as compounds of Formulae IIa, IIb, IIc, or IId and pharmaceutically acceptable salts thereof are disclosed. The compounds are useful in treating,...
8993584 Control agent for soft rot and control method for the same  
Providing a novel control agent for soft rot and a novel control method for the same. A compound having no antibacterial activity against Erwinia carotovora but having a control activity against...
8962599 Therapeutic compositions comprising imidazole and imidazolium compounds  
Therapeutic compositions comprising substituted imidazole or imidazolium compounds may be used for a number of medical purposes, such as treatment of undesirable conditions or diseases, including...
8940780 N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form anti-allergic, anti-inflammatory and hypolipidemic agents  
The present invention relates to N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof wherein n is 2 or 3; andR1 represents or pharmaceutically acceptable salts thereof,...
8921403 Combinations of imazalil and hydroxypyridones  
The present invention relates to combinations of imazalil, or a salt thereof, and hydroxypyridones which provide an improved biocidal effect. More particularly, the present invention relates to...
8901161 Therapeutic compositions comprising imidazole and imidazolium compounds  
Therapeutic compositions comprising at least two substituted imidazole or imidazolium compounds may be used for a number of medical purposes, such as treatment of undesirable conditions or...
8901162 Substituted imidazolium compounds for treating disease  
The present disclosure relates to therapeutic compositions comprising substituted imidazoliums having multiple acidic groups. The compounds may be used to treat diseases or conditions such as...
8877754 Compounds, pharmaceutical compositions and uses thereof  
The invention relates to new compounds of the formula I to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
8865757 Therapeutic compositions comprising imidazole and imidazolium compounds  
Therapeutic compositions comprising at least two substituted imidazole or imidazolium compounds may be used for a number of medical purposes, such as treatment of undesirable conditions or...
8852648 Delivery of biologically-active agents using volatile, hydrophobic solvents  
A composition and method adapted for delivery of hydrophilic, biologically-active agents are disclosed. The composition can include a reverse microemulsion formed from at least one hydrophilic,...
8846764 Methods of modulating cell proliferation and cyst formation in polycystic kidney and liver diseases  
The present invention provides a method for preferentially reducing the proliferation of cystic epithelial cells in the kidney or bile duct in a mammal in need thereof by administering a 20-HETE...
RE45173 Inhibitors of CYP 17  
The present invention provides compounds of Formula (I) and (II), or a pharmaceutically acceptable salts thereof, where R53, R54, p, q, and n are as defined herein. The compounds of the present...
8809333 Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents  
The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.
8790685 Bioadhesive gel based on hydroxyethylcellulose  
Disclosed are compositions in the form of a bioadhesive gel that adheres to the mucous membranes, in particular the vaginal mucosa, for the application of active ingredients and/or principles,...
8778913 Antimicrobial compositions for treating microbial infections  
The disclosure provides compounds and methods to treat a microbial or a bacterial pathogenesis, and demonstrates that the S. aureus pigment is a virulence factor and potential novel target for...
8759385 Composition comprising azole fungicide and water soluble metal salt  
Hair treatment composition comprising an azole fungicide and zinc gluconate and wherein the composition does not comprise Trichogen®.
8748469 IDO inhibitors  
Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R1, R4, and R5 are defined herein. Such compounds and...
8729101 1H-imidazole derivative having CB1, agonistic, CB1 partial agonistic or CB1 antagnistic activity  
The present invention relates to a group of novel 1H-imidazole derivatives, to methods for the preparation of these compounds, and to pharmaceutical compositions containing one or more of these...
8722720 Imidazole derivatives as IDO inhibitors  
Presently provided are IDO inhibitors of general formulae (VII), (VIII) as shown below and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase;...
8722102 Compositions for treatment of skin and ear infections  
The present invention relates to a composition for the treatment of skin and ear infections in humans and animals such as dogs, cats and horses. In particular, the present invention relates to a...
8703649 Pesticidal suspo-emulsion compositions  
The present invention relates to formulation comprising at least (i) two pesticidal compounds A and B dissolved in a lactic acid ester and wherein a) both A and B have melting points below 900 C...
8691235 Absorbable crystalline polyether-ester-urethane-based bioactive luminal liner compositions  
Bioactive hydroforming luminal liner compositions are formed of an absorbable crystalline amphiphilic polyether-ester-urethane dissolved in a liquid derivative of a polyether glycol that undergoes...
8686010 Aryl- or heteroaryl-sulfonyl compounds as acid secretion inhibitors  
The present invention provides a compound having a superior acid secretion inhibitory action, an antiulcer activity and the like. A proton pump inhibitor containing a compound represented by the...
8669252 Prolylcarboxypeptidase inhibitors  
Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to the...
8664255 Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof  
The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in...
8653126 Imidazole derivative  
To provide a novel compound or an isotope thereof or a pharmaceutically acceptable salt thereof having S1P lyase inhibitory capacity and inducing the decrease in number of lymphocytes, and a...
8653125 Cyclohexane derivative having NPY Y5 receptor antagonism  
The present invention discloses novel cyclohexane derivatives having NPY Y5 receptor antagonistic activity. Specifically, the present invention discloses a compound represented by the formula (I),...
8623900 Amino alcohol derivatives and their therapeutic activities  
The present invention relates to amino alcohol derivatives of general formula I: These derivatives possess an interesting activity in that they block the secondary products of lipid oxidative...
8609710 Cycloalkyl-substituted imidazole derivative  
A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein A represents a C3 to C12 cycloalkyl group which may be substituted by one to...
8598217 Imidazole derivatives and their use as modulators of cyclin dependent kinases  
The invention provides compounds of the formula (I): and salts, tautomers, solvates and N-oxides thereof; wherein Q is CH or N; X is N, N+—O− or CR3; Y is N, N+—O− or CR3a; R1 and R2 are...
8598078 Condensed anthran I lami de derivatives as insecticides  
Compounds of Formula I wherein the substituents are as defined in Claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be...
8592419 Ceramides and apoptosis-signaling ligand  
The invention provides the compounds of formula (): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, A, X, Y, a, b and n are as defined herein. Also disclosed are methods for...
8569352 Imidazole based LXR modulators  
Compounds of the invention, such as compounds of Formulae IIa, IIb, IIc or IId, and pharmaceutically acceptable salts, isomers, and prodrugs thereof, are useful as modulators of the activity of...
8535698 Granular water dispersible agent and production process  
A water dispersible granule formulation prepared by pulverized a part of active ingredients into fine particles under wet milling and pulverized another part of the active ingredients into coarse...
8501743 Personal care composition  
A personal care composition comprising a eutectic mixture, the eutectic mixture comprising a tertiary system, in which menthol may form part of the eutectic mixture or in the eutectic mixture...
8486985 Selective subtype alpha 2 adrenergic agents and methods for use thereof  
The invention provides methods for treating disorders associated with selective subtype modulation of alpha 2 adrenergic receptors. In particular, the invention provides methods employing...
8455497 Inhibitors of aspartyl protease  
The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease...
8409550 Method for treating skin with retinoids and retinoid boosters  
A skin care product comprising from about 0.001% to about 10% of a retinoid, in combination with 0.0001% to about 50% of at combination of retinoid boosters.
8329745 Small molecule inhibitors of ghrelin O-acyltransferase  
Ghrelin O-acyltransferase (GOAT) is inhibited with designed small molecules of the general formula: Methods comprise contacting the GOAT with an inhibitor and detecting a resultant inhibition.
RE43816 Granular water dispersible agent and production process  
A water dispersible granule formulation prepared by pulverized a part of active ingredients into fine particles under wet milling and pulverized another part of the active ingredients into coarse...
8309589 Fluorine-containing organosulfur compound and pesticidal composition comprising the same  
There is provided a fluorine-containing organosulfur compound having an excellent controlling effect on arthropod pests represented by the formula (I): wherein m represents 0 or 1; n represents 0,...
8309608 Use of eNOS transcription enhancers in the cell therapy of ischemic heart diseases  
The present invention relates to the use of compounds which enhance the transcription of endothelial nitric oxide synthase (eNOS) for treating stem and progenitor cells in the cell therapy of...
8298558 Granular water dispersible agent and production process  
A water dispersible granule formulation prepared by pulverized a part of active ingredients into fine particles under wet milling and pulverized another part of the active ingredients into coarse...
8288315 Fungicide mixtures  
Fungicidal mixtures comprising, as active components: 1) metconazole of the formula I and 2) prochloraz of the formula II, in a synergistically effective amount, and also compositions comprising...
8283376 Use of substituted 2-aminotetralins for preventive treatment of parkinson's disease  
The invention relates to the use of substituted 2-aminotetralins of general formula (I) as a medicament for the preventive treatment of Parkinson's disease.
8263635 Inhibitors of CYP 17  
The present invention provides compounds of Formula (I) and (II), or a pharmaceutically acceptable salts thereof, where R53, R54, p, q, and n are as defined herein. The compounds of the present...
8236843 Anti inflammatory compounds  
Biphenyl compounds of Formula (I) and Formula (II), and their pharmaceutically acceptable salts or solvates or prodrugs, their pharmaceutical compositions, their use and process of preparation are...