|
Match
|
Document |
Document Title |
|
|
6884821 |
Carboxylic acid derivatives and drugs containing the same
Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the...
|
|
|
6867229 |
Antiparasitic composition for the treatment and protection of pets
Composition which is useful in particular for the treatment and protection of domestic animals which are infested with parasites or are likely to be infested with them, these compositions...
|
|
|
6849634 |
Potassium channel inhibitors
Compounds useful as potassium channel inhibitors and especially useful for the treatment of cardiac arrhythmias and cell proliferative disorders are described.
|
|
|
6846837 |
Topical administration of basic antifungal compositions to treat fungal infections of the nails
Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a...
|
|
|
6838476 |
Imidazoles with anti-inflammatory activity
Compounds of formula I wherein: one of X or Y represents N and the other represents C; R 1 represents hydrogen, methyl, halogen, cyano, nitro, —CHO, —COCH 3 or —COOR 4 ; PR 2 represents...
|
|
|
6833381 |
TNF-α inhibitors
TNF-α inhibitors containing a heterocyclic compound having angiotensin II antagonistic activity which are useful as preventives/remedies for inflammatory diseases, etc.
|
|
|
6821965 |
Amidobenzamide derivatives which are useful as cytokine inhibitors
The invention concerns amide derivatives of the Formula (I) wherein R 3 is (1-6C)alkyl or halogeno; Q is aryl or heteroaryl which optionally bears 1, 2, 3 or 4 substituents such as hydroxy,...
|
|
|
6821997 |
Therapeutic and prophylactic treatment of aging and disorders of aging in humans
A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of cell-specific carbonic anhydrase enzymes in the brain,...
|
|
|
6803367 |
Substance for inducing apoptosis
A substance for inducing apoptosis represented by specific formulae. A pharmaceutical composition which can be used for an anticancer agent containing said substance.
|
|
|
6770667 |
Amide compounds
The present invention is a compound and pharmaceutical composition comprising a compound of formula (I): wherein R 1 is a 4-(lower) alkyl-imidazol-1-yl or a 4,5-di(lower) alkyl-imidazol-1-yl...
|
|
|
6770306 |
Drugs for reducing vaginal acidity and treatment of vaginitis, and the use thereof
The present invention relates to a pharmaceutical composition for reducing vaginal acidity, treating abnormal enhancement of vaginal acidity, and high acidity vaginitis associated with abnormal...
|
|
|
6740659 |
Treatment of dyskinesia
The invention relates to the use of compounds which inhibit selectively mu opioid receptor activity, or activation, for the treatment of dyskinesia (which, for example, may arise as a side effect...
|
|
|
6737434 |
Imidazole derivatives or their salts
Imidazole derivatives of the formula (1) or salts thereof, pharmaceuticals containing the derivatives or the salts, and intermediates for the synthesis of the derivatives or the salts (wherein R 1 ...
|
|
|
6737418 |
Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and the use thereof
This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R 5 -R 13 are set in the specification. The...
|
|
|
6734202 |
Fungicidal mixtures
The invention relates to a novel fungicidal composition comprising a fungicidally acceptable carrier and/or surface active agent together with, and synergistically effective amounts of (a) at...
|
|
|
6723753 |
Substituted n-benzyl-n-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer...
|
|
|
6713501 |
Supplement for dialysis patients
Use of a tablet diet supplement for administration to a dialysis patient comprising a mixture of L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine, L-threonine,...
|
|
|
6710056 |
Amidinophenylpyruvic acid derivatives
An amidinophenylpyruvic acid derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an excellent antagonistic effect against activated blood...
|
|
|
6703411 |
Substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
Benzoylguanidines of the formula (I) in which R1 to R4 have the meanings given in the specification and claims are suitable as antiarrhythmic medicaments having a cardioprotective component for...
|
|
|
6656954 |
Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds
A sulfonyl divalent aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises...
|
|
|
6653335 |
Pharmaceutical composition for inhibiting the growth of viruses and cancers
This invention is a method of treating cancer, both carcinomas and sarcomas, and viral infections, in particular HIV through the administration of a pharmaceutical composition containing a...
|
|
|
6632840 |
Monoacyl-substituted guanidines, a process for their preparation, their use as a medicament or diagnostic aid, and pharmaceutical compositions containing them
Monoacyl-substituted guanidines of formula III, or a salt or acid thereof, and their use as medicine or diagnostic aid: in which X(2) is
|
|
|
6627647 |
Substituted 1-(4-aminophenyl)imidazoles and their use as anti-inflammatory agents
A compound of Formula Ia wherein: R 1 and R 2 , which are the same or different, are CF 3 ; halogen; CN; branched or unbranched C 1-8 alkyl; branched or unbranched C 1-8 alkenyl; C 3-8 ...
|
|
|
6617344 |
Heterocyclically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
Heterocyclically substituted benzoylguanidines of the formula I in which the substituents R(1) to R(4) have the meanings indicated in the claims. These compounds I are suitable as antiarrhythmic...
|
|
|
6610664 |
Cationic lipids
The present invention is directed to new cationic lipids and intermediates in their synthesis that are useful for transfecting nucleic acids or peptides into prokaryotic or eukaryotic cells. The...
|
|
|
6610716 |
Cyanomethyl substituted thiazoliums and imidazoliums and treatments of disorders associated with protein aging
Provided, among other things, is a compound of the formula:
|
|
|
6610721 |
Imidazo heterocyclic compounds
A novel class of imidazo heterocyclic compounds, pharmaceutical compositions comprising them and use thereof in the treatment and/or prevention of diseases and disorders related to the histamine H3...
|
|
|
6602514 |
Use of ectoine or ectoine derivatives in cosmetic formulations
The use of one or more compounds chosen from the compounds of the formulae Ia and Ib the physiologically compatible salts of the compounds of the formulae Ia and Ib and the stereoisomeric forms...
|
|
|
6602849 |
Cyclic somatostatin analogs
The present invention is directed to cyclic derivatives containing an imidazole cis amide bond mimetic which bind selectively to somatostatin receptor subtypes and the use thereof in treating...
|
|
|
6596745 |
Method for treating fibrotic diseases with azolium chroman compounds
Provided is a method of treating or ameliorating hypertension in an animal comprising administering an effective amount of a compound of formula I:
|
|
|
6583167 |
Methods and kits for treating and diagnosing leiomyomas
This invention provides methods of treating a subject suffering from a leiomyoma which comprise administering to the subject a therapeutically effective amount of an agent, or alternatively a...
|
|
|
6582683 |
Dermal barrier composition
Disclosed is a dermal barrier composition which contains a hydrophilic polymer emulsion and a hydrophobic polymer emulsion. The dermal barrier composition is moisture activated, and remains inert...
|
|
|
6573289 |
Naphthalene derivatives, their production and use
A composition containing a compound of the formula: wherein A is a nitrogen-containing heterocyclic group which may be substituted, R 1 is a hydrogen atom, hydrocarbon group which may be...
|
|
|
6573288 |
Substituted sulphonyl cyanamides, method for producing same and their use as medicament
The invention relates to compounds of formula (I) in which the symbols have the meanings given in the claims. Said compounds are inhibitors of the sodium-dependent bicarbonate/chloride ion...
|
|
|
6566386 |
Immunomodulating and antiinflammatory agent
In the present invention, pharmaceutical compositions containing a histamine-added gamma-globulin as an effective component are used as an immunomodulating agent, a suppressive agent for...
|
|
|
6565894 |
Healthcare formulations comprising imidazole and hydrogen peroxide
An ophthalmic solution comprising: 0.01 to 5 weight percent imidazole: 0.01 to 30 weight percent hydrogen peroxide and the balance water which can further comprisie 0.01 to 2 weight percent of a...
|
|
|
6562855 |
Anaesthetic formulation comprising an NMDA-antagoinst and an alpha-2 adrenergic agonist
A pharmaceutical composition is described. The composition comprises a formulation. The formulation comprises an NMDA antagonist and an alpha-2 adrenergic agonist. In a preferred aspect, there is...
|
|
|
6562861 |
Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors
Compounds I-III wherein U is CH, O, or S; Z is mono- or di-substituted carbon; R is (CH2)nCO2H, (CH2)nSO3H, (CH2)nPO3H2, (CH2)nNO2, CH(SCH3)3, esters; R1 is H, hydroxyalkyl, aminoalkyl,...
|
|
|
6562846 |
Bisarylimidazolyl fatty acid amide hydrolase inhibitors
The present invention relates to bisarylimidazolyl derivatives and pharmaceutical compositions comprising said compounds inhibiting fatty acid amide hydrolase and useful for the treatment of pain,...
|
|
|
6558952 |
Treatment for diabetes
Methods and compositions for treating diabetes mellitus in a patient in need thereof are provided. The methods include administering to a patient a composition providing a gastrin/CCK receptor...
|
|
|
6555141 |
L-ergothioneine, Milk thistle, and S-adenosylmethionine for the prevention, treatment and repair of liver damage
This invention provides therapeutic compositions for the protection, treatment and repair of liver tissue. The invention relates to novel compositions comprising two or more compounds selected from...
|
|
|
6548521 |
Inhibitors of metazoan parasite proteases
Compositions and methods for treating a patient infected with a metazoan parasite by inhibiting the enzymatic action of the metazoan parasite protease, wherein there is employed at least one...
|
|
|
6541478 |
Smoking cessation treatments using naltrexone and related compounds
Nicotine dependency is treated by administration of an opioid antagonist. In some embodiments, rapid or ultra rapid detoxification techniques include using a combination of an effective amount of...
|
|
|
6537525 |
Medicated chewing-gum
The present invention is directed to chewing-gum preparations which are particularly useful for treating gastroesophageal reflux disease. Typically, the chewing-gum preparation comprises a...
|
|
|
6528535 |
Bicyclic inhibitors of protein farnesyl transferase
The present invention provide compounds of Formula I The present invention also provides a method of treating cancer and treating or preventing restenosis or atherosclerosis. Also provided by...
|
|
|
6525082 |
Apoptosis inducer
A substance for inducing apoptosis represented by specific formulae. A pharmaceutical composition which can be used for an anticancer agent containing said substance.
|
|
|
6518287 |
Substituted imidazoles as dual histamine H1 and H3 agonists or antagonists
The present invention discloses novel substituted imidazole compounds which have either or dual histamine-H 1 and H 3 receptor antagonist activity as well as methods for preparing such compounds....
|
|
|
6514966 |
Compounds for the treatment of obesity
NPY antagonists, methods of using such NPY antagonists and pharmaceutical compositions containing such NPY antagonists. The NPY antagonists are useful for the treatment of NPY mediated...
|
|
|
6509366 |
Substituted imidazoles as selective modulators of Bradykinin B2 receptors
Disclosed are compounds of the formula: or the pharmaceutically acceptable non-toxic salts thereof wherein Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 R 7 ′ are variables defined herein, which...
|
|
|
6500448 |
Composition for sustained release of human growth hormone
A pharmaceutical composition for the sustained release of human growth hormone from a polymer matrix is disclosed. The pharmaceutical composition comprises a biocompatible polymer, particles of...
|