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4324793 4-Nitro-2-trichloromethylphenyl disulfides  
4-Nitro-2-trichloromethylphenyl disulfides, their manufacture, agents containing these compounds as active ingredients for use on microorganisms, and the use of these compounds for protecting...
4317825 Antitumor and immunosuppressive 4-carbamoyl imidazolium-5-olate derivatives  
There are provided compounds of the formula: ##STR1## wherein R is a heteroaroyl group containing a nitrogen, sulfur or oxygen atom which may be substituted with a lower alkyl group, an aralkyl...
4287199 Benzimidazolylcarbamic acid esters substituted on the benzenoid nucleus by an oxy or thio substituent  
The invention relates to 2-benzimidazolylcarbamic acid esters, substituted on the benzenoid nucleus by an aminoalkoxy, aminoalkylthio, an aminoalkylsulphinyl or an aminoalkylsulphonyl grouping. The...
4273783 (1-Alkyl-5-nitro-2-imidazolyl)-vinyl-glyoxal-diacetals, their preparation and their use  
(1-Alkyl-5-nitro-imidazolyl)-vinyl-glyoxal-diacetals of the formula: ##STR1## in which R and R' are each alkyl of 1 to 5 carbon atoms, are useful in the treatment of infections caused by protozoa,...
4272543 Pharmacologically active 4,5-diaryl-2-substituted-imidazoles  
Imidazole derivatives of the formula ##STR1## wherein AR 1 and AR 2 are independently each phenyl; phenyl substituted by halogen, C 1 -4 alkyl, C 1 -4 alkoxy or C 2 -6 dialkylamino; pyridyl;...
4271158 Vasodilating or antidepressant phenalkanolaminoalkyl-substituted imidazolidinones  
Racemic and optically active compounds of the formula Q--C n H 2n --NH--R wherein Q is ##STR1## where R 1 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms,...
4269847 Antiinflammatory-4,5-diphenyl-2-substituted-thio-imidazoles and their corresponding sulfoxides and sulfones  
Imidazole derivatives of the formula ##STR1## wherein Ar 1 and Ar 2 are each phenyl; phenyl substituted by halogen, C 1 -4 alkyl, C 1 -4 alkoxy or C 2 -6 dialkylamino; pyridyl; furyl; or thienyl;...
4258054 Hydantoin derivatives as therapeutic agents  
A series of spiro-hydantoin compounds has been prepared by condensing the appropriate carbonyl ring compound, such as the corresponding 1-indanone, 1-tetralone, 4-chromanone, thiochroman-4-one,...
4241060 Nitroimidazoles and compositions thereof  
Nitroimidazoles of the formula ##STR1## wherein R 1 and R 2 are as hereinafter set forth, are described. The nitroimidazoles are useful as hypoxic-cell radiosensitizers, as well as being useful...
4241072 Substituted ureas and processes for their preparation  
Organic chemical compounds based upon the urea molecule are disclosed which have potent gastric secretion inhibitory properties. The urea is substituted with a heterocyclic ring which may be...
4226874 Pharmacologically active thiourea and urea compositions and methods of use  
The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.
4218457 2-Substituted 5-hydroxy-1H-imidazole-4-carboxamide derivatives and use  
Compounds of the formula, ##STR1## wherein R is C 2 -C 17 alkyl group, C 3 -C 7 cycloalkyl group, 1-adamantyl group, pyridyl group, pyridine N-oxide, diphenylmethyl group, benzyl group which...
4211783 Hypolipidemic and antiatherosclerotic novel 4-(aralkyl- and heteroarylalkylamino)phenyl compounds  
This disclosure describes novel 4-(aralkyl- and heteroarylalkylamino)phenyl compounds useful as hypolipidemic and antiatherosclerotic agents.
4207325 4-Substituted pyrazoles  
Pyrazoles of the formula ##STR1## wherein R is hydrogen, alkyl, aryl, aralkyl, trifluoromethyl or a heterocycle; R 1 is aryl or aralkyl unsubstituted or substituted by halo, trifluoromethyl,...
4199580 3-Amino-2-or-propoxy-tetrahydronaphthyl or indanyl-substituted imidazoles and use  
Novel 3-amino-2-OR-propoxy-tetrahydronaphthyl or indanyl substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity...
4190666 Anti-inflammatory 4,5-diarly-2-(substituted-thio)imidazoles and their corresponding sulfoxides and sulfones  
Anti-inflammatory 4,5-diaryl-2-(substituted-thio)imidazols and their corresponding sulfoxides and sulfones useful for treating arthritis and related diseases.
4182770 Alcohol deterrent  
1-(4-nitrophenyl)-2-methyl-4-nitroimidazole has been found to be highly useful as an alcohol deterrent.
4182769 Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones  
Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones useful for treating arthritis and related diseases.
4179512 4-Substituted-2-arylimidazoles  
4-Substituted-2-arylimidazoles, wherein the 4-substituent is sulfur containing, are disclosed. The compounds have pharmaceutical activity.
4177281 Therapeutic treatment for measles viral infection  
The administration internally to humans of 1-(β-hydroxethyl)-2-methyl-5-nitromidazole, (metronidazole) in a dosage range for adult humans of about 31 to 2,500 mgs per twenty-four hour period, is...
4159338 Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones  
Antiinflammatory 4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones, such as, 4-(4-fluorophenyl)-2-(1,1,2,2-tetrafluoroethylsulfonyl)-5-(2 -thienyl)-1H-i...
4152436 Acylated pentadienone hydrazone, method for preparing the same, and use as fire ant control agents  
There are provided certain acylated pentadienone hydrazones, and methods of use of said compounds for the control of insects, especially Lepidopterous insects, and for the control of ants, Family...
4140788 N-Substituted imidazolecarboxamide derivatives  
N-Substituted imidazolecarboxamide compounds represented by the formula; ##STR1## wherein R 1 is hydrogen atom, lower alkyl, lower alkenyl, aralkyl, R 2 is hydrogen atom, lower alkyl, lower...
4122190 Treating acromegaly  
α-Adrenoceptor agonists are useful in the treatment of acromegaly.
4118502 Amidinoformic and amidino-sulphinic acid derivatives  
Amidinoformic acids and amidinosulphinic acids which are histamine H 2 -antagonists. Two specific compounds of the present invention are N-[2-(5-methyl-4-imidazolylmethylthio)-ethyl]amidinoformic...
4118461 1-Substituted aralkyl imidazoles  
This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in...
4105763 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles  
New 1-methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles are disclosed as well as a process for their manufacture. The new compounds are suitable for the treatment of protozoal diseases and show a...
4105762 Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlli  
This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in...
4089968 Stable solutions of ipronidazole  
Solutions of ipronidazole are disclosed which have excellent stability and physiological acceptance and thereby are amenable to parenteral administration. The subject preparations utilize as the...
4073928 Therapeutic treatment for viral regional ileitis infection  
The administration internally to humans of 1-(β-hydroxyethyl)-2-methyl-5-nitromidazole, (metronidazole) in a dosage range for adult humans of about 31 to 2,500 mgs per 24 hour period, is an...
4072749 Use of ipronidazole in combatting clostridial infections  
The use of ipronidazole and water-soluble, pharmaceutically acceptable salts thereof in the prevention and treatment of clostridial infections in domestic animals is described.
4060640 Therapeutic agents  
O-HALOBENZYLIDENEAMINOGUANIDINES ARE EMPLOYED AS CENTRAL NERVOUS SYSTEM DEPRESSANTS, AS CARDIOVASCULAR DEPRESSANTS, AND/OR AS ANTIDEPRESSANTS FOR OVERCOMING PSYCHIC DEPRESSION.
4056621 Imidazolylmethylthioethyl dithiocarbamate compounds  
The compounds are dithiocarbamates and isothioureas which are histamine H 2 -antagonists. Two compounds of the invention are 2-(5-methyl-4-imidazolylmethylthio)ethyl N-methyldithiocarbamate and...
4042703 Method of treating and preventing coccidiosis  
The present invention relates to new compositions, containing as active ingredient 4-nitro-5-carbamoyl-imidazole derivatives, which compositions are for the treatment and prevention of coccidiosis...
4041168 Nitroimidazole derivative with antibacterial activity  
The compound 5-[(1-hydroxy-1-methyl)ethyl]-1-methyl-2-nitroimidazole is valuable in combatting Trichomonas vaginalis infections in mammals.
4038410 Nitroimidazole derivatives and process for the preparation thereof  
Nitroimidazoles of the formula ##STR1## wherein R is dialkylaminoacryloyl; 3-, 4-, or 5-pyrazolyl or a mixture thereof which is unsubstituted or substituted by alkyl or, at the 1-position, by...
4032645 Injectable metronidazole composition  
An injectable solution suitable for the systemic treatment of anaerobic infections is prepared by solubilization of 500-650 mg. metronidazole in 10 ml. of a solvent system comprised of: 25-35%...
4031232 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles and process for their manufacture  
1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles are described as well as a process for their manufacture. The compounds are active against trichomonads and amoebae and are especially suitable for the...
4020166 Haloalkyl esters of 5-nitroimidazole-1-carboxylic acid derivatives  
This invention provides compounds of the formula, ##STR1## in which R 1 signifies straight or branched chain alkyl in which a single methyl group is replaced by a mono-, di- or tri-halomethyl...
4000296 Imidazole alkylguanidine compounds  
The compounds are guanidines, for example N-benzenesulphonyl-N'-[2-((4-methyl-5-imidazolyl)-methylthio )ethyl]guanidi ne, which are inhibitors of histamine activity.
3968220 Imidazole insecticides  
Method for insect control and insecticidal compositions containing substituted imidazoles as the active insecticidal agents for agricultural and horticultural use.
3968228 4-Nitro-5-cyanoimidazoles as coccidiostats  
4-Nitro-5-cyanoimidazoles substituted with a 1-loweralkyl group and variously substituted at the 2-position are useful as antiparasitic agents particularly as coccidiostats. The...
3961068 Use of ipronidazole in combatting Sphaerophorus necrophorus infections  
The use of ipronidazole and water-soluble, pharmaceutically acceptable salts thereof in the prevention and treatment of infections in domestic animals caused by Sphaerophorus necrophorus is described.
3952103 Herpes viral infection treatment  
The administration internally to humans of 1-(β-hydroxethyl)-2-methyl-5-nitromidazole, (metronidazole) in a dosage range for adult humans of about 31 to 1,000 mgs per twenty-four hour period, is...
3856966 TREATMENT OF VIRAL INFLUENZA INFECTIONS  
The administration internally to humans of 1-(β-hydroxyethyl)-2-methyl-5-nitroimidazole, (metronidazole) in a dosage range for adult humans of about 31 to 1,000 mgs per 24 hour period, is an...
3796561 1,3-DISUBSTITUTED-2-TRICHLOROMETHYL-5-IMINO-1,3-IMIDAZOLIDINONES AS HERBICIDES  
Compound of the formula ##SPC1## Wherein Y is oxygen or sulfur, R 1 is alkyl of 1 to 8 carbon atoms substituted with 0 to 3 halogen atoms or aryl of 6 to 10 carbon atoms substituted with 0 to 3...
3715433 GROWTH PROMOTION IN SWINE  
Compositions and methods for promoting the growth and increasing the feed efficiency of swine, comprising orally administering to the swine a composition comprising either (a)...
3626069 GROWTH PROMOTION  
Growth promotion in animals is achieved by administration of 1-methyl-5-nitroimidazol-2-methyl carbamate in feed and/or water.
3549756 ANTITRICHOMONAL COMPOSITIONS CONTAINING 1-SUBSTITUTED - 2 - MORPHOLINYL OR THIAMORPHOLINYL-5-NITROIMIDAZOLES  
3502776 COMPOSITIONS AND METHODS FOR COMBATING TURKEY BLACKHEAD