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4328234 |
Imidazole derivatives and salts thereof and pharmaceutical formulations useful in thrombo-embolic disorders
Imidazoles of formula (I) ##STR1## wherein A is a chemical bond or a straight or branched, saturated or unsaturated, aliphatic residue having from 1 to 6 carbon atoms wherein 1, 2 or 3 of such...
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4324784 |
Process for preventing growth of marine organisms on a substance using hydrogen peroxide
A process for preventing growth of marine animals, i.e. shellfish, Polyzoa, and Hydrozoa on a surface, characterized by supplying hydrogen peroxide and/or a hydrogen peroxide-generating agent into...
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4317830 |
Treatment of shock
The invention relates to a class of imidazoles substituted by cycloalkyl or cycloalkenyl which have pharmacological properties making them useful in medicine, in particular in the prophylaxis and...
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4301170 |
1-Dimethyl substituted alkyl-2-or 4-substituted phenylimidazoles
This disclosure describes novel compounds of the formula ##STR1## wherein R 1 and R 2 each represent hydrogen, or ##STR2## and R 3 is hydrogen or fluoro, and n is 1, 2 or 3, and provided that...
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4298604 |
Clotrimazole-betamethasone dipropionate combination
Antifungal compositions comprising clotrimazole and betamethasone dipropionate are disclosed.
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4284641 |
Pharmaceutically active imidazole derivatives
The invention relates to a class of imidazoles substituted by cycloalkyl or cycloalkenyl which have pharmacological properties making them useful in medicine, in particular in the prophylaxis and...
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4282238 |
Insecticidal process
Insecticidal agents containing, as active ingredients, imidazole derivatives or salts thereof. The imidazole derivatives have the formula ##STR1## where R 1 denotes branched alkyl of 6 to 20...
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4281019 |
4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents
This disclosure describes 4-[(unsaturated or cyclopropylated alkyl)amino]phenyl compounds and derivatives useful as hypolipidemic and antiatherosclerotic agents.
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4275071 |
Imidazole derivatives
Imidazole derivatives of the formula I and pharmaceutically acceptable acid addition salts thereof are provided: ##STR1## In the formula, R 4 1- or 2-naphthyl, optionally substituted with Cl, Br,...
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4267169 |
Novel preparation of clotrimazole
A new type of preparation of clotrimazole, such as gel preparation, creamy preparation and liquid preparation, which are useful for an external use for the treatment of various trichophytoses,...
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4256752 |
Treatment of ulcers with acylated aminoalkyl cyanoguanidines containing a heterocyclic residue
There are prepared compounds corresponding to the formula ##STR1## in which X is a 5-membered or 6-membered aromatic heterocyclic radical which is attached through a carbon atom to the adjacent CH...
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4251540 |
Combating crop damaging fungi with α-(4-biphenylyl)-benzyl-azolium salts
α-(4-Biphenylyl)-benzyl-azolium salts of the formula ##STR1## in which A is CH or N, R 1 and R 2 each independently is hydrogen, alkyl or optionally substituted phenyl, R 3 is hydrogen,...
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4243671 |
Inhibition of thromboxane synthetase formation and arachidonic acid-induced platelet aggregation and bronchoconstriction
1-(3-Phenyl-2-propenyl)-1H-imidazole, and its hydrochloride salt have been found to be potent inhibitor of thromboxane synthetase and therefore an inhibitor of arachidonic acid-induced platelet...
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4239759 |
Morpholino containing compounds, compositions and use thereof
Compounds of the formula R--A--Z wherein R is a 4-biphenylyl or 4-phenoxyphenyl or a corresponding group monosubstituted or polysubstituted by one or more of F, Cl, and Br; A is --CH(CH 3 )--CH 2...
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4238498 |
Antimycotic substituted diphenyl-imidazolyl-methanes
The invention provides a series of substituted diphenyl-imidazolyl-methanes useful as antimycotic agents. Also included in the invention are pharmaceutical compositions containing said...
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4237158 |
1-Substituted aralkyl imidazoles and their use as fungicides
This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in...
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4230717 |
Indomethacin-antihistamine combination for gastric ulceration control
An anti-inflammatory and analgesic composition containing indomethacin and an H 2 histamine receptor antagonist in an amount sufficient to reduce gastric distress caused by the indomethacin....
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4213990 |
1,1-Diphenylethene derivatives as microbicides
Diphenylethene derivatives of the formula I given herein are new, very valuable microbicides. They can be used on their own or in the form of pesticidal compositions for combating or preventing...
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4211782 |
Pharmaceutical combination
Combinations comprising an anti-aggregatory substance together with one or more of an anti-oxidant and a thromboxane A 2 synthetase inhibitor are disclosed. Combinations are useful for the...
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4194001 |
Synergistic insecticidal compositions
Synergized insecticidal and acaricidal compositions comprise a compound of Formula I wherein Y is H or CN, Z is phenyl, or 2,2-dichlorovinyl and R is (i) a group of Formula II where X is Cl or Br,...
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4183940 |
Antimycotic imidazolyl-9,10-dihydro-anthracene derivatives
The invention provides new azolyl-9,10-dihydroanthracene derivatives of the formula ##STR1## in which A represents a CH group or a nitrogen atom, B represents a CO group or a group of the...
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4177277 |
Method for alleviating hypertension
A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering an effective amount of a compound having the general formula ##STR1##...
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4173644 |
Thiourea compounds, compositions and methods and use
The compounds are dithiocarbamates and isothioureas which are histamine H 2 -antagonists. Two compounds of the invention are 2-(5-methyl-4-imidazolylmethylthio)ethyl N-methyldithiocarbamate and...
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4166845 |
Antidandruff shampoo compositions containing an aminopolyureylene resin
This invention relates to a high-foaming antidandruff shampoo having desirable cosmetic conditioning properties, which consists essentially of about 10% to 30% by weight of a water-soluble betaine...
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4143137 |
Substituted arylcyanoalkyl and diarylcyanoalkylimidazole metal salt complexes and fungicidal compositions and methods utilizing them
This invention relates to substituted arylcyanoalkyl and diarylcyanoalkylimidazoles, their acid addition salts and their metal salt complexes and their use as broad spectrum protectant-eradicant...
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4118487 |
Substituted azol-1-ylmethanes
Azol-1-ylmethanes substituted on the methane carbon atom by (a) phenyl or lower alkyl and (b) by a biphenyl-4-yl, 4-phenoxyphenyl, 4-phenylthiophenyl, 4-phenylsulfinylphenyl or...
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4118502 |
Amidinoformic and amidino-sulphinic acid derivatives
Amidinoformic acids and amidinosulphinic acids which are histamine H 2 -antagonists. Two specific compounds of the present invention are N-[2-(5-methyl-4-imidazolylmethylthio)-ethyl]amidinoformic...
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4118461 |
1-Substituted aralkyl imidazoles
This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in...
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4117142 |
Disubstituted triphenylmethylmidazoles for treating mycotic infections
Imidazoles of the formula ##STR1## and pharmaceutically acceptable nontoxic salts thereof, wherein X is methyl or chloro, Y is methyl or chloro, or, when Z is methyl or chloro, Y is hydrogen,...
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4105762 |
Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlli
This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in...
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4104382 |
Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors
Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors by administering an antihistamine and an H-2 histamine receptor inhibitor. Exemplary of the antihistamine in...
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4085209 |
Preparation and safening effect of 1-substituted imidazole metal salt complexes
This invention concerns the preparation of 1-substituted imidazole metal salt complexes and their use particularly as systemic fungicides. The preparation of the metal salt complexes of these...
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4067989 |
1,3-Diazole heterocyclic compounds and their use as pesticides
Plant fungicidal compounds of formula: ##STR1## WHEREIN R 3 is alkyl, furyl, thienyl or phenyl, R 4 is hydrogen, halogen, nitro, phenyl, alkoxy or alkyl, n is 1, 2 or 3, and Z is C=O or a...
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4065572 |
Amino acids and esters thereof useful as antihypertensive agents
A compound of the formula ##STR1## possesses antihypertensive activity. Also provided are methods for the preparation of the compounds as well as pharmaceutical formulations and methods for their...
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4062965 |
Quaternary imidazole compounds as microbicides
This invention relates to novel compounds having the formula: ##STR1## wherein R 1 is a straight-chain alkyl group having 8 to 18 carbon atoms, R 2 is a straight-chain alkyl group having 1 to 3...
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4058491 |
Cationic hydrogels based on heterocyclic N-vinyl monomers
Novel cationic hydrogels, containing basic (cationic) groups in their molecular structure, and processes for their preparation are described. These novel hydrogels are stable, three-dimensional...
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3996370 |
Antagonism of ethanol intoxication with 4[(4,5-dihydro-2-1H-imidazolyl)methoxy]-N,N,2-trimethylbenzenamine
A novel method for combatting ethanol intoxication and narcosis in animals by administering an effective amount of the compound 4[(4,5-dihydro-2-1H-imidazolyl)methoxy]-N,N,2-trimethylbenze
namine...
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3991201 |
1-(β-Aryl-β-R-ethyl)imidazoles as antimicrobial agents
Compounds of the class of 1-(β-aryl-β-R-ethyl)imidazoles, useful as antibacterial and antifungal agents.
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3954982 |
Pharmaceutical compositions and method of inhibiting H-1 and H-2 histamine receptors
Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors by administering an antihistamine and an H-2 histamine receptor inhibitor. Exemplary of the antihistamine in...
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3949076 |
N-(Heterocycl ic-alkyl)-9-xanthenylamines
The compounds are N-(imidazolylalkyl, imidazolinylalkyl and tetrahydropyrimidylalkyl)-9-xanthenylamines which have gastric acid secretion inhibitory activity.
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3934022 |
N-trityl-imidazoles as plant fungicides
Plant fungicidal compositions are produced which comprise an amount of a compound of the formula: ##EQU1## wherein R is alkyl of 1 to 3 carbon atoms, sufficient to be effective for killing,...
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3832466 |
3-AZOLYLPROPYNE FUNGICIDAL AGENTS
Fungicidal and bactericidal compositions comprising, and methods of combating fungi and bacteria using 3-azolylpropynes of the general formula ##SPC1## In which R 1 is hydrogen, chlorine, bromine,...
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3812260 |
2,4,5-HALOGENIMIDAZOLES FOR COMBATING INSECTS AND ACARINA
The use of 2,4,5-halogenimidazoles of the formula ##SPC1## order Wherein X 1 , X 2 and X 3 each denote a halogen atom, with the proviso that at least one of the substituents X 1 , X 2 and X 3 ...
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3725549 |
N-TRITYL-IMIDAZOLES FOR CONTROLLING PLANT FUNGI
Plant fungicial compositions are produced which comprise an amount of a compound of the formula: ##SPC1## Wherein R is chloro, bromo or fluoro, or a salt thereof, sufficient to be effective for...
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3719760 |
N-TRITYL-IMIDAZOLIUM SALTS AS A FUNGICIDE
Plant fungicidal compositions are produced which comprise an amount of a compound of the formula: ##SPC1## Wherein Y is the anion of an inorganic or organic acid, sufficient to be effective for...
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3549756 |
ANTITRICHOMONAL COMPOSITIONS CONTAINING 1-SUBSTITUTED - 2 - MORPHOLINYL OR THIAMORPHOLINYL-5-NITROIMIDAZOLES
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3546341 |
COMPLEXES OF 2-SUBSTITUTED BENZIMIDAZOLES AND BIS-HALOGENATED PHENOLS IN ANTHELMINTIC COMPOSITIONS AND METHODS
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3436463 |
PESTICIDAL COMPOSITIONS COMPRISING N-SUBSTITUTED GAMMA HYDROXYCARBOXYLIC ACID AMIDES
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3359158 |
Imidazole pyrazole and oxazole insecticides for fiber eating insects
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3344018 |
Biocidal quaternary ammonium sulfamates
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