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9040570 Compounds for anti-fungal treatment  
Provided are methods of treating or preventing a fungal infection in a subject. The methods comprise selecting a subject with or at risk of developing a fungal infection and administering to the...
9029377 Platelet-activating factor receptor antagonists  
Cyclohexyl sulfonamide compounds which are platelet-activating factor (PAF) receptor antagonists. Said compounds may be useful, for example, for the treatment of atherosclerosis or other...
9023483 Wood preservative compositions useful for treating copper-tolerant fungi  
The present invention provides a method of protecting wood or other celiulosic material from decay by copper-tolerant fungi, and wood preservative formulations for use in the same. The wood...
9023874 Fluorinated oxa or thia heteroarylalkylsulfide derivatives for combating invertebrate pests  
The invention relates to alkylsulfide derivatives compounds of formula I as hereunder depicted or the enantiomers or veterinarily acceptable salts thereof which are useful for combating or...
9012489 Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament  
Substituted phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones which are glycine transporter-1 (GlyT1) inhibitors. These are useful for the treatment of schizophrenia, Alzheimer's Disease and other...
9000017 Combinations of imazalil and silver compounds  
The present invention relates to combinations of imazalil, or a salt thereof, and silver compounds which provide an improved biocidal effect. More particularly, the present invention relates to...
8993584 Control agent for soft rot and control method for the same  
Providing a novel control agent for soft rot and a novel control method for the same. A compound having no antibacterial activity against Erwinia carotovora but having a control activity against...
8987302 Treatment of hepatitis C virus related diseases using hydroxychloroquine or a combination of hydroxychloroquine and an anti-viral agent  
Methods of treating a hepatitis C virus (HCV) related disease, such as HCV infections in subjects non-responsive to anti-HCV therapy, are described herein, comprising administering to the subject...
8980920 Antiviral compounds of three linked aryl moieties to treat diseases such as hepatitis C  
The present invention relates to novel Linked Tricyclic Aryl Compounds, compositions comprising at least one Linked Tricyclic Compound, and methods of using Linked Tricyclic Aryl Compounds for...
8980867 Biocide compositions comprising alkoxylated oligoglycerol esters  
Suggested are biocide compositions, comprising (a) Alkoxylated oligoglycerol esters; (b) Biocides and optionally (c) Oil components or co-solvents and/or (d) Emulsifiers. The compositions show...
8969396 Method for treating a B-raf associated cancer with an Hsp90 inhibitor  
The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating Bcr-Abl, FLT-3, EGFR, c-Kit, B-raf, and NPM-ALK associated...
8969392 Pesticide composition comprising propamocarb-fosetylate and an insecticidally active substance  
The present invention relates to a pesticide composition intended for protecting plants, crops or seeds against phyto-pathogenic fungi or damaging insects, and the corresponding methods of...
8969395 Triterpenoid derivatives useful as antiproliferative agents  
Formula (I) and (II). The present invention relates to the use of a new lupane derivative of general formula (I) or (II), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or...
8962244 Compounds for modulating RNA binding proteins and uses therefor  
The invention relates to compositions and methods for inhibiting RNA binding proteins (e.g., MEX-3, MEX-5 and POS-1), as well as methods for treating and preventing disorders associated with...
8962661 Fungicidal composition and method for controlling plant diseases  
To provide a fungicidal composition having stable and high fungicidal effects against cultivated crops infected with plant diseases resulting from plant diseases. A fungicidal composition...
8957096 Herbicidally active oxime-ether-substituted benzoylamides  
What is described are oxime ether-substituted benzoylamides of the general formula (I) as herbicides. In this formula (I), R, Y and Y are radicals such as hydrogen, organic radicals such as alkyl,...
8957063 Amine and ether compounds which modulate the CB2 receptor  
Compounds which modulate the CB2 receptor are disclosed. The compounds are useful for treating CB2 receptor-mediated diseases such as pain.
8952043 Benzoxepin PI3K inhibitor compounds and methods of use  
Benzoxepin compounds of Formula I, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, wherein: Z1 is CR1 or N; Z2 is...
8946272 Plymorphic forms of deferasirox (ICL670A)  
The invention relates to crystalline forms of 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid and to its amorphous form, to processes for the preparation thereof, to compositions...
8946236 Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents  
The present invention relates to new insecticides of the formula (I) in which R1, R2, R3, R4, R5, R6, A, Q and n can have the definitions stated in the description, to a number of processes for...
8946273 S-Triazolyl alpha-mercapto acetanilides as inhibitors of HIV reverse transcriptase  
A series of S-triazolyl α-mercaptoacetanilides having general structure (1) are provided, where Q is CO2H, CONR2, SO3H, or SO2NR2. The compounds inhibit several variants of the reverse...
8946231 P2X3, receptor antagonists for treatment of pain  
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or...
8946121 Antifungal compositions  
The present invention relates to new antifungal compositions and their use in the treatment of agricultural products.
8940774 Tris-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors  
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a...
8937094 Triazole compounds that modulate HSP90 activity  
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of...
8933111 Crystalline form of (2S,4R)-5-biphenyl-4-yl-2-hydroxymethyl-2-methyl-4-[(1H-[1,2,3]triazole-4-carbonyl)-amino]-pentanoic acid 5-methyl-2-oxo-[1,3]dioxol-4-ylmethyl ester  
The invention provides a crystalline form of (2S,4R)-5-biphenyl-4-yl-2-hydroxymethyl-2-methyl-4-[(1H-[1,2 ,3]triazole-4-carbonyl)amino]pentanoic acid 5-methyl-2-oxo-[1,3]dioxol-4-ylmethyl ester or...
8921359 Inhibitors of beta-secretase  
The present invention is directed to a compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof. Pharmaceutical composition comprising a compound...
8921406 5-ring heteroaromatic compounds and their use as binding partners for 5-HT5 receptors  
The invention relates to 5-ring heteroaromatic compounds of general formula (I), their use for the treatment and/or prevention of diseases, and medicaments containing same.
8916502 Agent for improving lawn grass qualities  
An agent for improving lawn grass quality, which is excellent in promoting dwarfing of lawn grass, making the stem sturdy, increasing the leaf count, and improving greenness, is provided. An agent...
8916597 Use of pyraclostrobin as safener for triticonazole for controlling harmful fungi  
(1) Use of pyraclostrobin of the formula I as safener for (2) triticonazole of the formula II or salts or adducts thereof for controlling harmful fungi. The use of the compounds I and II in a...
8916183 Pesticidal compositions and processes related thereto  
This document discloses molecules having the following formulas (“Formula One” &“Formula Two” and “Formula Three”) The Ar1, Het, Ar2, R1, R2, R3, R4, and R5 are further described herein.
8916598 Compounds, compositions, and methods for the treatment of β-amyloid diseases and synucleinopathies  
Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of synucleinopathies, such as observed...
8906885 Treating cancer with HSP90 inhibitory compounds  
Methods of treating cancer with a compound of formulae (I) or (1a) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of...
8901125 Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors  
In one aspect, the invention relates to substituted bicyclic alkoxy pyrazole analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the...
8901156 Compounds and methods  
Disclosed are compounds having the formula: wherein X1, X2, X3, R1, R2, R3, R4, Y, A, Z, L and n are as defined herein, and methods of making and using the same.
8895594 Microbicidal composition  
Synergistic microbicidal compositions containing N-methyl-1,2-benzisothiazolin-3-one.
8895584 Inhibitors of c-fms kinase  
The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts...
8895595 Microbicidal composition  
Synergistic microbicidal compositions containing N-methyl-1,2-benzisothiazolin-3-one.
8889197 Plant pathogen inhibitor combinations and methods of use  
Combinations, compositions and methods of use for modulating plant pathogen infection using plant extracts containing anthraquinone derivatives which induce resistance to plant phytopathogens and...
8889594 Agent for improving good rice seedling growth  
There is provided an agent for improving the growth of seedlings, having effects of raising healthy rice seedlings, such as increase of the tillering number, increase of root weight, enhancement...
8883835 Plant disease controlling composition and method for controlling plant disease  
There is provided a plant disease controlling composition comprising at least one compound (A) selected from the group consisting of metconazole, bromuconazole and epoxyconazole, as well as a...
8871792 Neprilysin inhibitors  
In one aspect, the invention relates to compounds having the formula X: where Ra, Rb, R2, R7, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. The...
8865755 Dual-acting antihypertensive agents  
In one aspect, the invention relates to compounds having the formula: wherein: Ar, r, Z, X, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These...
8859607 Crystalline complexes of agriculturally active organic compounds  
The present invention relates to crystalline complexes comprising at least one agriculturally active organic compound A having at least one functional moiety which is capable as serving as a...
8859599 Androgen receptor modulating compounds, preparation and uses thereof  
The present invention concerns compounds of general formula (I): Method of preparation and uses thereof.
8846738 Fungicide active substance combinations  
The novel active compound combinations comprising 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropy l]-2,4-dihydro-[1,2,4]-triazole-3-thione of the formula and the active compound of...
8846566 Composition for controlling plant diseases and method for controlling plant diseases  
PROBLEM There are provided a composition for controlling plant diseases and a method for controlling plant diseases having excellent control effect for plant diseases.SOLUTIONA composition for...
8846739 TGR5 agonists  
TGR5 agonists of structural formula VIII(Q), wherein X, R1, R2, and R5 are defined in the specification, pharmaceutically acceptable salts thereof, compositions thereof, and use of the compounds...
8846737 Compound  
There is provided a compound of formula I wherein Z is selected from N and CR22, wherein R22 is H or a bond with D;wherein D is selected from a bond, C═O, and linear or branched hydrocarbon groups...
8829016 Triazole compounds as potential anti-inflammatory agents  
The present invention relates to a compound of formula 1 or 2 wherein R1 represents straight-chain or branched C2-C8 alkyl, C2-C8 alkenyl, optionally substituted by at least one substituent...