Matches 201 - 250 out of 253 < 1 2 3 4 5 6 >
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4654356 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs  
7-Oxabicycloheptane substituted diacid diamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q...
4652576 7-oxabicycloheptane substituted amide-carbamate prostaglandin analogs  
7-Oxabicycloheptane substituted amide-carbamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q...
4652578 7-oxabicycloheptane substituted amide prostaglandin analogs  
Cis-exo 7-oxabicycloheptane substituted amide prostaglandin analogs are provided having the structural formula ##STR1## wherein A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; R is CO 2 H, CO...
4647573 7-oxabicycloheptane substituted thioamide-amide prostaglandin analogs  
7-Oxabicycloheptane substituted thioamideamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q...
4639461 7-oxabicycloheptane substituted keto-amide prostaglandin analogs useful in the treatment of thrombotic disease  
7-Oxabicycloheptane substituted keto-amide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q is...
4638002 2,3,4-trinor-1,5-inter-meta-phenylene-prostacyclin compounds useful in inhibiting thrombocyte aggregation  
The invention relates to new 2,3,4-trinor-1,5-inter-m-phenylene-PGI 2 derivatives of the formula (I) ##STR1## wherein A stands for carboxy, cyano, tetrazolyl or --COOR 3 or --CONR 1 R 2 ; R...
4632931 7-oxabicycloheptane substituted amide-sulfonamide prostaglandin analogs useful in the treatment of thrombotic disease  
7-Oxabicycloheptane substituted amide-sulfonamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5;...
4602022 N-imidazolyl derivatives of bicyclic compounds  
Compounds of the formula (I) ##STR1## wherein the symbol represents a single or a double bond; each of R 1 , R 2 , R 3 and R 4 , which may be the same or different is (a) hydrogen;...
4600709 Benzodioxole derivatives, processes for the manufacture thereof and corresponding pharmaceutical compositions  
The invention relates to novel benzodioxole derivatives of the general formula I ##STR1## in which R 1 represents an unsubstituted or substituted, aliphatic, aromatic or heteroaromatic radical, ...
RE32196 Aurone derivatives  
Substituted aurones of formula (I): ##STR1## wherein R 1 , R 2 R 3 , R 4 , R 5 and R 6 are the same or different and can each represent hydrogen, halogen, C 1 -6 alkyl, C 1 -6 alkoxy, C 3 -8...
4596814 Tetrazolyl- and carboxamidotetrazolyl-substituted 4H-furo[3,2-b] indoles and anti-allergic use thereof  
Novel tetrazolyl- and carboxamidotetrazolyl-substituted 4H-furo[3,2-b] indoles are useful for treating allergies or for treating or ameliorating postmyocardial infarct tissue damage. Also disclosed...
4596804 Dibenz[b,e]oxepin compounds  
A dibenz[b,e]oxepin compound having an antiallergic activity is represented by the following general formula: ##STR1## wherein R 1 represents a cyano group, a 5-tetrazolyl group, a carbamoyl group...
4567201 Diphenoxypropane derivatives and compositions of antiasthmatic and antiinflammatory agents thereof  
A diphenoxypropane derivative of the formula: ##STR1## wherein X is a halogen atom, Y is a hydrogen atom or a hydroxy group and Z is a tetrazolyl or carboxy group, has excellent antiasthmatic and...
4563476 Substituted 5-hydroxy-2,3-dihydrobenzofurans and analogs thereof useful as anti-inflammatory agents  
Substituted 5-hydroxy-2,3-dihydrobenzofuran and analogs such as the substituted 6-hydroxy-2,3-dihydrobenzopyrans were prepared from an appropriately substituted...
4537904 Compositions of 7-oxabicycloheptane and 7-oxabicycloheptene compounds and a method for their use in inhibiting bronchoconstriction  
7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular...
4536507 Prostaglandin antagonists  
Prostaglandin antagonists are disclosed which are 7- and 8-substituted-dizenzo[b,f]thiepins of the structural formula: ##STR1##
4526896 Tetrazol-5-yl 2-nitro-3-phenylbenzofurans and antimicrobial use thereof  
Antimicrobial 2-nitro-3-phenylbenzofurans wherein the benzo or the 3-phenyl portion of the molecule is bonded to an alkylene or an oxyalkylene group which is in turn bonded to a basic nitrogen atom...
4507296 Tetrazoles, pharmaceutical use and compositions  
The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts or hydrates thereof, in which the substituents are defined later in the specification....
4495193 Imidazole compounds which reduce gastric acid secretion  
A compound having gastric acid secretion reducing activity and having the formula ##STR1## wherein each V and W, independently, is H, --CH 2 COOR 4 where R 4 is H or lower alkyl, --CH 2 CN, or...
4487776 Azolyl-phenoxy-tetrahydrofuran-2-ylidene-methanes, a process for their preparation, and antimicrobial agents which contain these substances  
The invention relates to azolyl-phenoxy-tetrahydrofuran-2-ylidene-methanes defined herein under formula (I). Also included in the invention are compositions containing said compounds of formula...
4486428 Bicyclic benzo fused compounds  
Bicyclic fused benzenoid compounds of the formula ##STR1## and pharmaceutically acceptable cationic and acid addition salts thereof, where M is O, CH 2 or NR 6 ; R 6 is hydrogen, formyl,...
4478843 5-Phenyltetrazoles and their use as salidiuretics  
What are disclosed are salidiuretic compounds of the formula ##STR1## and physiologically acceptable salts thereof, wherein R is phenyl, furyl or thienyl, intermediates of said compounds, methods...
4464381 Fungicides containing azolylmethyloxiranes  
Azolylmethyloxiranes of the formula ##STR1## where A and B are identical or different and independently of one another are each alkyl of 1 to 4 carbon atoms, naphthyl, biphenyl or phenyl, and the...
4432986 Tetrazoles bonded to certain polycyclic aromatic systems and anti-allergic use thereof  
Amides obtained by reaction of aminotetrazole and certain optionally substituted polycyclic aromatic acids are potent anti-allergic agents.
4406908 Tetrazolylcoumarin derivatives and antiallergic compositions containing the same  
Tetrazolylcoumarin derivatives of the general formula: ##STR1## wherein R is hydrogen atom, an alkyl group, an alkenyl group, an alkoxyalkyl group or phenyl group, n is an integer of 2 to 4, and...
4368201 Tetrahydronaphthoxazoles  
Compounds having the structure: ##STR1## are novel and useful as antiallergic agents. The compounds are formulated with a pharmaceutical carrier for oral, parental, inhalational, or rectal means of...
4364956 5-Substituted pyranone compounds and their use as pharmaceuticals to treat an immediate hypersensitivity condition  
Compounds are described of the formula ##STR1## in which R 1 is COOR 5 , CONHR 5 , cyano, 5-tetrazolyl or 5-tetrazolylaminocarbonyl, where R 5 is hydrogen or C 1 -6 alkyl; R 2 is hydrogen or C 1...
4363812 3-(Tetrazol-5-yl), 4-methyl-8-alkoxy coumarins and anti-allergic compositions thereof  
Coumarin derivatives of the general formula: ##STR1## wherein R is hydrogen atom, an alkyl group or an alkenyl group, R 1 is hydrogen atom, an alkyl group, an alkenyl group or an alkoxy group, and...
4360527 9-(Hydroxy, lower alkoxy or lower alkanoyloxy)-2-(1H-tetrazol-5-yl)naphtho-(2,1-b)-pyran-1-ones and anti-allergic use thereof  
This invention relates to Compounds of formula II: ##STR1## wherein Y is formyl, carboxylic acid, acrylic acid, cyano or tetrazolo; X is hydrogen, lower alkanoyl or lower alkyl, and their...
4316904 Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity  
Certain novel indolopyrone tetrazoles, carboxamidotetrazoles and their pharmaceutically acceptable salts are disclosed. These compounds are useful as antiallergic agents in mammals.
4309446 5-(Dihydroxyphenoxy)tetrazoles and use as sweeteners for medical compositions  
Dihydroxyphenoxy-1H-tetrazoles and their salts are used as non-nutritive sweeteners.
4293558 Antiviral thiazolinyl benzimidazoles and derivatives  
Certain thiazolinyl or thiazinyl ketobenzimidazole compounds and derivatives thereof are useful as antiviral agents.
4273782 Inhibition of thromboxane synthetase by 3-(1-Imidazolylalkyl) indoles  
Novel 3-(1-Imidazolylalkyl)indoles and the pharmaceutically acceptable acid addition salts thereof are disclosed. The novel compounds are useful in selectively inhibiting the action of the...
4244964 Heterocyclic derivatives of 1-(1,3-dioxolan-2-ylmethyl)-1H-1,2,4-triazoles  
Heterocyclic derivatives of 1-(1,3-dioxolan-2-ylmethyl)-1H-1,2,4-triazoles useful as anti-fungal and anti-bacterial agents.
4238495 1-(4-Cyano-phenoxy)-2-hydroxy-3-[2-(5-1H-tetrazolyl )-chromon-5-yloxy]-propane and salts thereof  
1-(4-Cyano-phenoxy)-2-hydroxy-3-[2-(5-1H-tetrazolyl)-chromon -5-yloxy]-propa ne and its pharmacologically acceptable salts, are useful in the treatment of allergies, allergic asthma and inflammation.
4228173 Thiopyrano-benzopyrans, compositions and method of use thereof  
There are described compounds of formula I, ##STR1## in which an adjacent pair of R 5 , R 6 , R 7 and R 8 form a chain --COCHCE--O--, and the remainder of R 5 , R 6 , R 7 and R 8 , which may...
4182764 Tetrazole derivatives of [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy(or thio)]alkanoic acids  
[1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acid, derivatives thereof, their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in...
4177257 Cyclic sulphur compounds  
Certain tricyclic sulphone compounds each of which is substituted in the 1-,2-,3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted in the 5-,6-,7- or...
4177285 [1-Oxo-2-thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids and derivatives thereof  
[1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkaoic acid, derivatives thereof, their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in...
4146631 Benzamide derivatives  
Benzamide derivatives of the formula:- ##STR1## wherein R 1 represents a fluorine, chlorine or bromine atom, or an alkyl, alkoxy, alkylthio, alkylsulphonyl, alkanoylamino, alkylamino or...
4133889 2(5-Tetrazolyl)chromones  
There are provided compounds of formula I, ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 7 may be the same or different, and are hydrogen, hydroxy, alkoxy, alkoxy substituted by phenyl,...
4124704 2-Nitro-3-phenylbenzofuran alkanoic (or propenoic) acids  
Optionally substituted 2-nitro-3-phenylbenzofuranalkanoic and -alkenoic acids which are active as antimicrobial agents, processes for their preparation and intermediates therefor are described.
4103015 Antiallergic cyclic sulphur compounds  
Certain tricyclic thioxanthone-10,10-dioxide compounds each of which is substituted in the 1-,2-,3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted...
4091108 Antiallergic pharmaceutical composition and use  
Certain tricyclic sulphoxide compounds each of which is substituted in the 1-,2-,3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted in the 5-,6-,7-...
4067993 Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids  
Optionally substituted 2-nitro-3-phenylbenzofurancarboxylic acids which are active as antimicrobial agents, processes for their preparation and intermediates therefor are described.
4064256 Benzopyranyltetrazoles as antiasthma agents  
There are described compounds of formula I, ##STR1## in which R 5 , R 6 , R 7 and R 8 , which may be the same or different, are hydrogen, alkyl C2 to 6, alkoxy C2 to 8, hydroxy-alkoxy C3 to 8, and...
4059704 Tetrazole coumarin derivatives  
A novel class of 3-tetrazole coumarins have anti-allergic activity. They are prepared by the action of ammonium azide on 3-cyano compounds.
4031236 Novel thiophene derivatives and their preparation  
Thiophene derivatives of the formula ##STR1## IN WHICH R x is --S--CHR 5 --CONHOH or --S--CHR 5 -5-tetrazolyl in which R 5 is H or alkyl of 1-6 carbon atoms and R y is 0-2 of alkyl or alkoxy...
4029802 The treatment of asthma, hay fever or urticaria  
There are described compounds of formula I, ##STR1## and pharmaceutically acceptable derivatives thereof, in which R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are the same or are different and each is a...
4025636 2-(Optionally substituted)phenyl-5 or 6-substituted benzoxazoles  
2-(Optionally substituted)phenyl-benzoxazoles having a carboxy alkyl, a tetrazolyl, or oxazolinyl group at the 5 or 6 position useful as aspirin-like non-steroidal, non-narcotic, analgesic,...
Matches 201 - 250 out of 253 < 1 2 3 4 5 6 >