|
Match
|
Document |
Document Title |
|
|
6362212 |
Oxime derivative and bactericide containing the same as active ingredient
A compound represented by general formula (I) or a salt thereof, a process for producing the same, an intermediate for the production thereof, and a bactericide (fungicide) containing the same as...
|
|
|
6362207 |
Methods of treating viral infections with benzimidazoles
This invention is a method of treating cancer, both carcinomas and sarcomas, and viral infections, in particular HIV through the administration of a pharmaceutical composition containing a...
|
|
|
6358942 |
Phenyloxazolidinones having a c-c bond 4-8 membered heterocyclic rings
A compound of Formula (I): or pharmaceutical acceptable salts thereof wherein X is NR 1 ; R 1 is H, C 1-6 alkyl optionally substituted with one or more OH, CN, or halo, or R 1 is —(CH 2 ) h...
|
|
|
6355661 |
Methods for treatment of sickle cell anemia
The preparation and use of a protected organic aldehyde is described wherein bioavailability of the orally administered therapeutic aldehyde is improved. The protected aldehyde is prepared by...
|
|
|
6353009 |
Method for the treatment and prevention of hyperuricemia
Insulin sensitivity enhancers, such as troglitazone, have the ability to treat and/or prevent hyperuricemia and may thus be used for the therapy or prophylaxis of such diseases as gout, urinary...
|
|
|
RE37556 |
Superoxide radical inhibitor
A superoxide radical inhibitor containing, as an effective ingredient, an azole derivative represented by the general formula (1), [wherein R 1 represents a phenyl group which may have 1-3...
|
|
|
6342490 |
Pharmaceutical composition containing uscharidin or its analogues
The invention provides compositions comprising uscharin and the use of uscharin to combat cell proliferation for example in the treatment of cancer. Administration of uscharin may kill or reduce...
|
|
|
6340694 |
Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors
The diarylbenzopyran derivatives represented by formula I, and the pharmaceutically acceptable salts thereof, are disclosed. The composition comprising the compound of formula I, or a...
|
|
|
6329418 |
Substituted pyrrolidine hydroxamate metalloprotease inhibitors
The invention provides compounds which are potent inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the...
|
|
|
6329148 |
Combined therapy of diterpenoid triepoxides and death domain receptor ligands for synergistic killing of tumor cells
A synergistic combination of ligands that interact with death domain receptors, and diterpenoid triepoxides is used to increase tumor cell killing by induction of apoptosis. Ligands useful in the...
|
|
|
6326387 |
Methods and compositions for stimulating neurite growth
The present invention relates to methods and pharmaceutical compositions for stimulating the growth of neurites in nerve cells. The compositions comprise a neurotrophic amount of a compound which...
|
|
|
6322749 |
Composition and method for inhibiting the growth of microorganisms including stabilized sodium hypobromite and isothiazolones
A synergistic composition and method for inhibiting microbiological growth which comprises a combination of stabilized sodium hypobromite with a mixture of 5-chloro-2-methyl 4-isothiazolin-3-one...
|
|
|
6323228 |
3-substituted indole angiogenesis inhibitors
3-Substituted indole carbohydrazides having the formula ##STR1## are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting...
|
|
|
6319949 |
Pesticidal sprays
A method for preventing fungal diseases in crops which comprises the steps of: (a) applying to a crop an aqueous or a non-aqueous spray composition which includes a pesticide and a spray adjuvant...
|
|
|
6319933 |
Azole derivatives
The present invention is directed to new 1-(1H-1,2,4-triazol-1-yl)butan-2-ol derivatives of the formula (I), ##STR1## and pharmaceutically acceptable salts thereof wherein Q, R, X, Y and Z are the...
|
|
|
6313090 |
Methods for treating parasitic infection using thiopeptides
The present invention provides a method for treating a parasitic infection in a subject infected with a parasite having a plastid-like organelle, comprising administering to the subject an...
|
|
|
6313132 |
Therapeutically active diarylpropylamines; their pharmaceutically acceptable salts; a method for their preparation and method for their use
The invention relates to novel compounds of Formula (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and Ar are as defined in claim 1, their salts with physiologically acceptable acids and,...
|
|
|
6313164 |
Dithiolin derivatives, their preparation and their therapeutic effect
Compounds of the formula (I): ##STR1## wherein one of m and n is 0, and the other is 0, 1 or 2; k is 0 or 1 to 12; R 1 is hydrogen, a substituent which is an aryl or a heterocyclic, or an...
|
|
|
6310081 |
Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
This invention provides compounds of Formula I having the structure ##STR1## wherein A, Q, R3, and R4 are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt...
|
|
|
6310050 |
Therapeutic use of compounds with β3-agonist activity
The invention relates to the method of use of compounds with B 3 -agonist activity for inhibiting uterine contractions, preventing or slowing down premature labor, or for the treatment and/or...
|
|
|
6306417 |
Wettable or water-soluble granular agrochemical composition
The present invention provides a wettable or water-soluble granular agrochemical composition which comprises a guanidine derivative of the formula: ##STR1## wherein R 1 represents a homocyclic or...
|
|
|
6306414 |
Aqueous suspension of agrochemical
The present invention relates to an aqueous suspension comprising (i) a compound of the formula: ##STR1## or a salt thereof, (ii) a condensate of formaldehyde with an aromatic sulfonic acid or a...
|
|
|
6306890 |
Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors
A compound of the formula ##STR1## where: n, and X are as defined in the specification, and the compound possesses selectivity for inhibition of cyclooxygenase-2.
|
|
|
6306887 |
Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
Compounds of Formula (1.0.0): ##STR1## are described wherein A is for example aryl, heteroaryl or heterocyclyl, Y is preferably --C(O)--; B is independently selected from a group of moieties,...
|
|
|
6303642 |
Use of 2-methyl-thiazolidine-2,4-dicarboxylic acid as a mucolytic agents
This invention relates to the use of 2-methyl-thiazolidine-2,4-dicarboxylic acid and/or its physiologically tolerable salts as mucolytic agents.
|
|
|
6300353 |
Azoles for treatment of fungal infections
Azole derivatives of the formula I ##STR1## wherein R 14 , R 15 are each independently hydrogen or fluorine, T is a group of the formula: ##STR2## wherein R 9 is pyrrolidinyl or a group...
|
|
|
6294559 |
Antiproliferative agents associated with peroxisome proliferator activated receptors gamma1 and gamma2
This invention is directed to compounds and ligands that bind to peroxisome proliferator activated receptors (PPAR) γ1 and γ2 and which function as antiproliferative, antiviral and antitumour...
|
|
|
6291493 |
Treatment of spinal cord injuries
The present invention relates to a new medical use of 5-(2-chloroethyl)-4-methylthiazole and the pharmaceutically acceptable salts and solvates thereof and pharmaceutical compositions containing...
|
|
|
6291491 |
Amide derivatives as β 3 agonists
Amide derivatives are selective β 3 adrenergic receptor agonists with very little β 1 and β 2 adrenergic receptor activity and as such the compounds are capable of increasing lipolysis and...
|
|
|
6291533 |
Dietary supplements for each specific blood type
Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.
|
|
|
6288071 |
1-ethylene-2-alkylene-1,4-cyclohexadiene pesticides
Pesticidally active cyclohexadienyl derivative compounds of the formula I that are esters, oximes or amides are claimed. These compounds may be used as fungicides, acaricides and insecticides in...
|
|
|
6281234 |
(2-Acylaminothiazole-4-yl)acetic acid derivative
This invention provides compounds of Formula I having the structure ##STR1## wherein R 1 , R 2 are both hydrogen or form a bond, or are each, independently, alkyl of 1-6 carbon atoms or aryl of...
|
|
|
6281235 |
Amino acyl amino propargyl diol compounds for treatment of a renin-mediated disease
Compounds characterized generally as amino acyl amino propargyl diol derivatives are useful as renin inhibitors for the treatment of a renin-mediated disease Compounds of particular interest are...
|
|
|
6277849 |
N-sulphonyl and N-sulphinyl amino acid amides as microbiocides
The invention relates to novel pesticidally active compounds of the general formula I ##STR1## as well as possible isomers and isomeric mixtures thereof, wherein n is a number zero or one; and ...
|
|
|
6277842 |
Dietary supplemental method for fat and weight reduction
A natural method for promoting fat, and weight loss while decreasing food cravings comprising administrating to an individual in need thereof L-carnitine, chromium, coenzyme Q10, creatine, lipoic...
|
|
|
6274607 |
N-linked ureas and carbamates of heterocyclic thioesters
This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as...
|
|
|
RE37303 |
Imidazole compounds and their therapeutic applications
A compound selected from the group consisting of a compound of the formula ##STR1## wherein the substituents are defined as in the specification having antagonist properties to histamine H 3 ...
|
|
|
6268391 |
Benzylidene-1,3-dihydro-indol-2-one derivatives a receptor tyrosine kinase inhibitors, particularly of Raf kinases
Compounds of general formula (I) wherein: R 1 is H or optionally joined with R 2 to form a fused ring selected from the group consisting of five to ten membered aryl, heteroaryl or heterocyclyl...
|
|
|
6262094 |
C-21 modified epothilones
The invention is concerned with epothilones in which the thiazole substituent has been modified, with methods for their preparation and with antifungal or therapeutic agents which contain these...
|
|
|
6262093 |
Methods of treating cancer with benzimidazoles
This invention is a method of treating cancer, both carcinomas and sarcomas, and viral infections, in particular HIV through the administration of a pharmaceutical composition containing a...
|
|
|
6255328 |
Substituted thiazolines and their use for controlling animal pests
The invention relates to novel substituted thiazolines of the formula (I) ##STR1## in which Ar 1 and Ar 2 each represent independently of one another optionally substituted phenyl, processes...
|
|
|
6251926 |
Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity
This invention provides a novel oxyiminoalkanoic acid derivative which has excellent hypoglycemic and hypolipidemic actions and which is used for the treatment of diabetes mellitus, hyperlipemia,...
|
|
|
6251898 |
Medical use of fluorenone derivatives for treating and preventing brain and spinal injury
Newly-created fluorenone drugs can be used to prevent, treat, or otherwise reduce damage to a brain or spinal cord following a medical crisis. These new drugs are markedly improved analogs of...
|
|
|
6248765 |
Imidazole derivatives as histamine receptor H3 (ANT) agonists
Novel imidazole derivatives as histamine receptor H 3 antagonists and/or agonists, preparation thereof and therapeutical uses thereof. Chemical compounds for use as histamine receptor H 3 ...
|
|
|
6245789 |
HIV and viral treatment
A pharmaceutical composition that can be used to treat viral infections, particularly HIV. The composition comprises from about 250 mg to about 6000 mg of a benzimidazole derivative of the formula:...
|
|
|
6245790 |
Oxazole compounds useful as PGE2 agonists and antagonists
Azole compounds of the formula: ##STR1## wherein R 1 is lower alkyl substituted with carboxy, etc., R 2 is hydrogen or lower alkyl, R 3 is aryl, etc. R 4 is aryl, etc. Q is ##STR2##...
|
|
|
6225329 |
Modulators of protein tyrosine phosphatases (PTPases)
The present invention provides novel compounds of Formula 1, compositions containing these compounds, methods of their use, and methods of their manufacture, where such compounds are...
|
|
|
6221377 |
Administration media for analgesic, anti-inflammatory and anti-pyretic drugs containing nitrous oxide and pharmaceutical compositions containing such media and drugs
Administration mediums comprising solutions of nitrous oxide in water, alcohols, ethers or oils, and optionally including essential fatty acids or C 1 -C 6 alkyl esters thereof enhance the action...
|
|
|
6211212 |
Pyrrolidine and thiazole derivatives with metallo-beta-lactamase inhibitory properties
|
|
|
6211215 |
Heterocyclic compounds, their production and use
Heterocyclic compounds represented by the general formula (I) ##STR1## wherein R stands for an optionally substituted aromatic heterocyclic group; X stands for oxygen atom, an optionally...
|