Matches 151 - 200 out of 303 < 1 2 3 4 5 6 7 >
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5583128 Contraception in female primates without affecting the menstrual cycle  
The invention relates to the use of aromatase inhibitors for contraception in female primates and to a method for contraception in female primates using such substances and to the use of those...
5580891 N-[heteroaryl-1-pyrrolidinyl)alkyl]-2-benoxazolinones and related compounds and their therapeutic utility  
Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a...
5578595 Cyclopropylacetic acid derivatives  
Novel 2-(2,2-difluorocyclopropyl)-acetic acid derivatives of formula I ##STR1## wherein A is oxygen or --NR 1 --, B is C 2 -C 6 alkylene, D is oxygen, sulfur or --O--CH 2 --, E is...
5571821 Sulfonamides and derivatives thereof that modulate the activity of endothelin  
Sulfonamides and methods using these sulfonamides for inhibiting the binding of an endothelin peptide to an endothelin receptor by contacting the receptor with the sulfonamide are provided. Methods...
5569655 Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof  
Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries...
5556855 N-heterocyclic substituted salicylic acids  
A compound of the formula Het--NR--SO 2 --Ph 2 --A--Ph 1 (COOH)(OH) and tautomic form, salts, solvates, C 1 -6 alkyl esters and pharmaceutical compositions of the compound. Ph 1 and Ph 2 are...
5552422 Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents  
The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a...
5550138 Condensed thiadiazole derivative, method of its production, and use thereof  
(1) a compound represented by the following formula (I): ##STR1## wherein R represents a hydrocarbon group or heterocyclic group which may be substituted; the ring A represents a pyridine ring...
5545656 2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease  
This invention relates to the use of certain 3-substituted 2-oxindole-1-carboxamides and their pharmaceutically acceptable base salts for the treatment or prevention of Alzheimer's disease in...
5543433 Azine-substituted phenylacetic acid derivatives and fungicides containing these  
Compounds of the formula I ##STR1## where X is hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, cyano or nitro, Y is an amino, methylamino or dimethylamino group, Z is a group CHCH 3 ,...
5534530 5-acylamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them  
The invention relates to thiadiazole derivatives corresponding to the general formula ##STR1## in which Ar represents a nitrogen-containing aromatic heterocycle, in particular indolyl which is...
5532256 New azolidinediones and thiadiazolidinediones as antihyperglycemic agents  
This invention relates to novel compounds which have demonstrated oral antihyperglycemic activity in diabetic ob/ob and db/db mice, animal models on non-insulin dependent diabetes mellitus (NIDDM...
5523312 Antipicornaviral agents  
Disclosed herein are compounds and pharmaceutical compositions useful for combating picornaviruses and preventing or treating picornaviral infections. The compounds have the formula: ##STR1##...
5523311 Process and a composition for immunizing plants against disease  
A method and composition for the immunization of healthy useful plants against plant diseases containing as active ingredients compounds of formula ##STR1## in which: X is hydrogen, halogen,...
5518987 Pesticide compositions for control of fungal disease in cultivated crops  
The present invention provides an effective method for controlling foliage and root fungus infection in cultivated crops. A fungicide composition in the form of an aqueous formulation which is...
5510359 Heteroaromatic 5-hydroxytryptamine receptor agonists  
A class of substituted five-membered heteroaromatic compounds possessing an imino spacer group are selective agonists of 5-HT 1 -like receptors and are therefore useful in the treatment of...
5510344 Acrylate fungicides  
Compounds of formula I ##STR1## wherein X is oxygen or sulphur, W is CH or N, m is 0 or 1, and either a) n is 1 and Q is a non-aromatic heterocyclic ring of 3 to 10 ring atoms, containing one to...
5500427 Cyclic compounds and their use  
The present invention relates to a compounds represented by the following formula or salts thereof. ##STR1## The above compounds have strong angiotensin II antagonistic action, antihypertensive...
5496835 Heterocyclic compounds having angiotensin II antagonistic activity and use thereof  
This invention relates to a compound represented by the formula ##STR1## wherein the ring A stands for a 5-10 membered aromatic heterocyclic group optionally having, besides R 1 and R 2 , further...
5482962 Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines  
This invention relates to N,N'-disubstituted-N,N'-diacylhydrazines which are useful as insecticides, compositions containing those compounds and methods of their use. This invention also relates to...
5439511 Coating varnish composition and antifouling coating composition  
A coating varnish composition comprising (A) a polymer obtained by polymerizing (a) at least one unsaturated acid anhydride and (b) at least one other unsaturated monomer, and (B) at least one...
5439512 Resin composition and antifouling paint  
A coating varnish composition comprising (A) a polymer obtained by polymerizing one or more unsaturated carboxylic acids (a) with one or more unsaturated monomers (b), and (B) at least one additive...
5438066 Oxa- and thiadiazole derivatives  
Fungicidal and insecticidal compounds having the general formula (I): ##STR1## or a stereoisomer thereof, wherein A is CH or N; B is OCH 3 or NHCH 3 ; one of L and M is N and the other is S or O;...
5409944 Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase  
Disclosed are compounds of Formula I useful in the treatment of cyclooxygenase mediated diseases such as pain, fever and inflammation of a variety of conditions including rheumatic fever, symptoms...
5405853 Thiadiazoles useful in the treatment of senile dementia  
A class of novel thiadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring system, and substituted on the other ring carbon atom with a substituent...
5405857 3-substituted 1,2,3,4,-oxatriazole-5-imine compounds, a process for the preparation thereof and a pharmaceutical preparation containing said compounds  
The present invention relates to hitherto unknown 3-substituted 1,2,3,4-oxatriazole-5-imine compounds which have proved to have biological effects making them suitable for treatment of...
5384321 Microbicidal compositions  
Compositions comprising, as active ingredients, compounds of the formula I ##STR1## in which: X 1 , X 2 and X 3 independently of one another are hydrogen, methyl, methoxy, methylthio, halogen or...
5366984 Methyl α-arylacrylates substituted by a heterocyclic radical and their use  
Methyl α-arylacrylates substituted by a heterocyclic radical and having the general formula ##STR1## where R is alkyl, alkenyl, haloalkyl, cycloalkyl, alkoxy, alkylcarbonyl, alkoxycarbonyl,...
5342849 Phenoxyalkyl-substituted heteroaromatics and a method for controlling pests  
Phenoxyalkyl-substituted heteroaromatics of the formulae Ia and Ib ##STR1## where the substituents have the following meanings: R 1 C 1 -C 12 -alkyl, C 2 -C 12 -alkenyl, C 2 -C 12 -alkynyl,...
5338737 Biphenyl oxadiazoles and thiadiazoles as angiotensin II antagonists  
Novel heterocyclic methyl derivatives of biphenyl oxadiazoles and thiadiazoles are described, as well as methods for the preparation of said derivatives and pharmaceutical compositions of the same,...
5332430 Use of thiadiazole compounds as an antifouling active ingredient  
The invention relates to thiadiazole compounds of the type ##STR1## wherein R 1 , R 2 , R 3 are hydrogen alkyl groups having 1-4 carbon atoms substituted alkyl groups having 1-4 carbon...
5310746 Alpha-methylene-6-styryl-acrylic acid derivatives  
All possible stereoisomer forms and mixtures of a compound of the formula ##STR1## wherein X is a halogen, R 2 and R 3 are individually selected from the group consisting of alkyl and cycloalkyl...
5302607 Compositions for protecting plants against disease  
Novel benzo-1,2,3-thiadiazole-7-carboxylic acid esters of formula ##STR1## in which Y is oxygen or sulfur; Q 1 and Q 2 independently of one another are each hydrogen or halogen; R 1 and R...
5298515 N-hetaryl-2-nitroanilines  
Abstract of the Disclosure: N-Hetaryl-2-nitroanilines Ia and Ib ##STR1## (R 1 =H, halogen, C 1 -C 4 -alkoxy; R 2 =NO 2 , CN, halogen, C 1 -C 4 -haloalkyl; R 3 =NO 2 , halogen, C 1 -C 6 ...
5292737 N,N'-bis(sulfonamido)-2-amino-4-iminonaphthalen-1-ones and N,N'-bis(amido)-2-amino-4-iminonaphthalen-1-ones  
N,N'-Bis(sulfonamido)-2-amino-4-iminonaphthalen-1-ones and N,N'-Bis(amido)-2-amino-4-iminonaphthalen-1-ones are disclosed. Methods of inhibiting protein kinase C activity which comprises contacting...
5290798 (hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis  
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They...
5281614 Substituted 1,2,4-triazoles bearing acidic functional groups as angiotensin II antagonists  
Novel substituted triazolinone, triazolinethione, and triazolinimine compounds of the formula I are useful as angiotensin II antagonists. ##STR1##
5254595 Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them  
Aryloxypropanolaminotetralins with beta-antagonist activity of the formula ##STR1## wherein R is hydrogen, hydroxy or methoxy and Ar is an optionally substituted aromatic or heteroaromatic group,...
5254574 New tetrazole derivatives, process for their preparation and their use  
Tetrazole derivatives of the formula ##STR1## in which R 1 denotes a saturated or unsaturated, straight-chain or branched (C 1 -C 6 ) alkyl radical and R 2 denotes methyl or ethyl, and their...
5248683 Benzo-1,2,3-thiadiazole derivatives  
Compounds of the formula ##STR1## in which A 1 and A 2 independently of one another are CO--C 1 -C 4 alkyl, COO--C 1 -C 4 alkyl, CO--CF 3 , CO--N(R) 2 or cyano; A 1 and A 2 together are...
5244906 Insect control with substituted oxadiazole and thiadiazole compounds  
Insects, especially sucking insects, such as brown planthoppers, and phytophageous mites, such as two-spotted spider mites, are controlled by applying an oxadiazole or thiadiazole compound...
5240950 Carbazate derivatives, their production and use  
There are provided carbazate derivatives of the formula: R 1 --NCH--NHNH--R 2 wherein R 1 is a heterocyclic group; and R 2 is an esterified carboxyl group, and their salts, which are useful...
5198445 Composition and use of substituted 3-thio-2-propynenitriles as industrial antimicrobials  
Substituted 3-thio-2-propynenitriles are prepared which correspond to the formula: R--S--C.tbd.C--C.tbd.N wherein R is an alkyl, cyclic alkyl, aryl, or heterocyclo group. These compounds have...
5190928 Process and a composition for immunizing plants against diseases  
A method and composition for the immunization of healthy useful plants against plant diseases containing as active ingredients compounds of formula ##STR1## in which: X is hydrogen, halogen,...
5134146 Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma  
The use of compounds for formula (I): ##STR1## or a salt or prodrug thereof; wherein one of X, Y, or Z is an oxygen or sulphur atom and the other two are nitrogen atoms, and the dotted circle...
5132316 Heterocyclic azabicyclic compounds for enhancing acetylcholine function  
A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which X represents R 1 OOC-- in which R 1 is C 1 -4 alkyl, C 2 -4 alkenyl or C 2 -4 alkynyl; R 2 O-- in which...
5126349 Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial  
Substituted 3-thio-2-propynenitriles are prepared which correspond to the formula: R--S--C.tbd.C--C.tbd.N wherein R is an alkyl, cyclic alkyl, aryl, or heterocyclo group. These compounds have...
5118683 Esters of 4-hydroxy-1,3-benzenedimethanol and compositions and methods employing such compounds  
Compounds of the formula I ##STR1## wherein R 5 represents C 1 to C 6 -alkyl or the group --(CH 2 ) n --Z--(CH 2 ) m --Ar; Z represents O, S or --CH 2 --; n represents an integer of 1...
5114958 1,2,4-oxadiazole and 1,2,4-thiadiazole derivatives of fenamates as antiinflammatory agents  
1,2,4-Oxadiazole and 1,2,4-thiadiazole derivatives of the fenamic acids, in which the fenamate residue is present at the 3-position of the 1,2,4-oxadiazole or 1,2,4-thiadiazole, pharmaceutically...
5112841 Imidazole derivatives and antiepileptics comprising said imidazole derivatives as effective ingredients  
Described herein are imidazole derivatives having a specific structure and satisfactory as antiepileptics from the standpoint of the strength of action, prolonged action and side effects as well as...
Matches 151 - 200 out of 303 < 1 2 3 4 5 6 7 >