Matches 151 - 200 out of 300 < 1 2 3 4 5 6 >
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5559134 Leukotriene-B.sub.4 antagonists, process for their production and their use as pharmaceutical agents  
The invention relates to leukotriene-B 4 antagonists of formula I ##STR1## in which n represents a whole number from 2 to 5, X represents a direct bond, 1 to 6 methylene units, an ortho-, meta-...
5556644 Nutritional supplement for the elderly  
A multinutrient nutritional supplement is provided that is designed to be most effective in increasing the immunity and decreasing the instances and severity of infection particularly among older...
5552418 Trisubstituted Naphthylalkylamides  
The invention relates to a compound selected from those of formula (I): ##STR1## in which R, R 1 , R 2 and R 3 are as defined in the specification, and a medicinal product containing said...
5536735 Pharmaceutical composition  
This invention comprises a pharmaceutical composition comprising a benzimidazole compound having antiulcer activity and a water-soluble carboxylic acid amide. According to this invention, a...
5516784 Anti-HIV (AIDS) agents  
Compounds of formula ##STR1## wherein Ar, W, Z, Q, R 1 , U, and T are as set forth herein, are described. These compounds are active as agents against retroviruses and in particular against HIV.
5512586 Medicaments based on pyridine-2,4- and 2,5-dicarboxylic acid amides  
The invention relates to pyridine-2,4- and -2,5-dicarboxylic acid derivatives of the formula I ##STR1## in which R 1 , R 2 , 3 3 , R 4 and X have the meanings given, a process for the preparation...
5504081 Combating fish parasites  
The present invention relates to the use of agonists and antagonists of the nicotinergic acetylcholine receptors of insects for combating fish parasites.
5478848 Inhibition of arthritis by L-type calcium channel antagonists nimodipine, nisoldipine and nifedipine  
The present invention comprises new methods for treating rheumatoid arthritis. It has been found that the L-type calcium channel antagonists are effective in treating arthritis. Nimodipine,...
5470846 Treatment of neurological and mental disorders  
A method of treating neurological and mental disorders which are associated with and/or related pathogenetically to deficient serotonin neurotransmission and impaired pineal melatonin functions in...
5466690 Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid like activity  
Retinoid-like activity is exhibited by compounds of the formula ##STR1## where R is hydrogen or lower alkyl; A is pyridyl, thienyl, furyl, pyridazinyl, pyrimidinyl or pyrazinyl; n is 0-5; and B is...
5446057 Substituted tetrahydropyridine and piperidine carboxylic acids as muscarinic antagonists  
Substituted tetrahydropyridines and piperidinecarboxylic acids and derivatives thereof are described, as well as methods for the preparation and pharmaceutical composition of same, which muscarinic...
5431925 Nutritive composition for prevention and therapy of infection diseases caused by immunosuppression  
Disclosed is a nutritive composition for patients being treated with anticancer drugs, which comprises 1-5 mg weight % of a retinoid compound in the solid content of the composition composed of...
5430049 Treating hyperproliferative disorders  
This invention describes a method for the treatment of a patient afflicted with a hyperproliferative disorder which comprises administering to a patient a effective amount of a compound which is an...
5428026 Liposoluble antioxidant mixture  
A liposoluble antioxidant composition contains a group B vitamin-organic acid complex and a lecithin rich in phosphatidyl choline.
5428039 Method for electively achieving reversible hyperpolarized cardiac arrest  
While performing cardiopulmonary bypass, the aorta is cross-clamped and the beating heart is stopped by introducing of an ATP-dependent potassium channel opening agent. The infusion into the...
5420145 Carboxylic acid derivative  
Carboxylic acid derivatives having potent retinoid-type pharmacological activities are disclosed. The compounds disclosed are represented by the following formula: ##STR1## wherein R 1 , R 2 , and...
5416117 Cyclopropenone derivatives  
A novel cyclopropenone derivative (I) which possesses a potent inhibitory activity against thiol protease such as papain, cathepsin B, cathepsin H, cathepsin L, calpain or the like with excellent...
5416103 N-cyclohex(en)yl-pyridine carboxamides and compositions containing them for controlling fungal pests  
N-Cyclohex(en)ylcarboxamides of the formula I ##STR1## where: R is substituted or unsubstituted alkyl, alkoxy, alkenyl, alkenyloxy, alkynyl, alkynyloxy, cycloalkyl, cycloalkenyl, cycloalkyloxy,...
5360806 Amide compounds and their salts and pesticidal compositions containing them  
The present invention relates to an amide compound and its salt, process for its production and a pesticidal composition containing it. The amide compound of the formula (I) or its salt: ##STR1##...
5340565 Tumor or cancer cell killing therapy and agents useful therefor  
The effectiveness of cytostatic and/or cytotoxic drugs and/or radiation in the killing of tumor and/or cancer cells is increased by the administration, along with said drugs and radiation, of an...
5332751 Pyridine carboxamide compounds which have useful as pharmaceutical utility  
Sulfonamide derivatives of the general formula (I): ##STR1## wherein preferably R 1 represents a lower alkoxy group, R 2 , R 3 , R 4 , R 5 , R 6 and R 7 may be the same or different from one...
5326762 Inhibitors of acyl-coenzyme A: cholesterol acyl transferase  
Amides of the formula ##STR1## wherein R 1 and R 2 are independently heteroaryl, X-substituted heteroaryl, X-substituted phenyl, N-substituted triazinyl or N-substituted imidazolyl; and in...
5294624 Antihyperlipidemic cinnamide derivatives  
Novel cinnamamide derivatives and the salts thereof are provided. An antihyperlipidemic composition is also provided. The composition comprises an active ingredient which is at least one selected...
5276045 Thioformamide derivative, process for its preparation, pharmaceutical composition thereof and treatment method  
A thioformamide derivative of the formula: ##STR1## wherein R represents alkyl, A represents optionally substituted pyrid-3-yl, isoquinolin-4-yl, tetrahydroquinolin-3-yl, quinolin-3-yl,...
5270301 Fluoro-amide derivatives  
The present invention relates to certain fluoro-amide derivatives, as described herein, which are human leukocyte elastase (HLE) inhibitors making them useful whenever such inhibition is desired,...
5262419 Method for the prophylaxis and/or treatment of ulcerative gastrointestinal conditions using a potassium channel activator  
Ulcerative conditions of the gastro-intestinal tract, e.g., antiinflammatory-drug-induced ulcers, are treated or prevented by the administration of a potassium channel activator. Methods and...
5260323 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use  
2,4- and 2,5-substituted pyridine-N-oxides are provided which are effective as fibrosuppressives and immunosuppressives. Said compounds are also suitable for the treatment of disorders of the...
5244653 Glycine anhydride dimethylol as a biocide and preservative  
The use of glycine anhydride dimethylol, also known as 1,4-bis(hydroxymethyl)-2,5-piperazinedione, comprising the formula ##STR1## to kill microorganisms present in or on a host substance and to...
5242936 Phenoxy alkanol esters for treatment of allergic conditions  
Compounds of the formula: ##STR1## wherein R 1 is at position 4 and either is an alkyl group of 1-6 C or is an --(CH 2 ) 3 -- which is additionally linked to the phenyl at position 3 thereof; ...
5225422 Pyridine compounds which are useful as leukotriene B4 antagonist  
Leukotriene B 4 antagonists of the formula: ##STR1## wherein each symbol is as defined in the specification, processes for producing them, and pharmaceutical compositions containing them. The...
5215738 Benzamide and nicotinamide radiosensitizers  
A method for radiosensitizing hypoxic tumor cells in a warm-blooded animal is provided. The method involves administration of a nicotinamide compound having the structural formula ##STR1## wherein...
5211943 Pharmaceutical preparation for administration by percutaneous absorption and a method for their manufacture  
A pharmaceutical preparation for percutaneous absorption comprising a base material and fine crystals of Nicorandil and/or salts of Nicorandil that are evenly distributed throughout said base...
5204357 Renin-inhibiting amino acid derivatives  
The invention relates to compounds of the formula I ##STR1## in which A represents a substituted thio-, sulfinyl- or sulfonyl-alkanoyl radical or a four- to eleven-membered heterocycle, B is an...
5198216 Performance enhancing compositions of matter, and methods of preparing and utilizing same  
A composition for enhancing the performance of animals, such as horses or dogs, is composed of adrenal and pituitary raw tissue concentrates, vitamin C, bioflavonoid complex, pantothenic acid,...
5196184 Pharmaceutical preparation  
Pharmaceutical preparation containing Nifedipin as the active substance together with a solution promoter, such as, for example, copolyvidon or polyvinylpyrrolidone and/or...
H001139 Combination of a calcium channel blocker and thromboxane A.sub.2 receptor antagonist or synthetase inhibitor and method for treating ischemia employing such combination  
A method is provided for treating ischemia in a mammalian species by administering a combination of a calcium channel blocker such as diltiazem, SQ 31,765 or SQ 32,324 and a thromoboxane A 2 ...
5153208 Pyridine-2,4- and -2,5-dicarboxylic acid amides and their medicinal compositions and methods of use  
The invention relates to pyridine-2,4- and -2,5-dicarboxylic acid derivatives of the formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and X have the meanings given, a process for the preparation...
RE34075 Dermal uses of trans-retinoids for the treatment of cancer  
The dermal use of non-irritating retinoids such as the esters and amides of 13-cis and 13-trans-retinoic acid for effecting the reduction and reversal of photoaging and skin cancer is disclosed.
5137889 Dihydropyridine derivatives and process for preparing the same  
Dihydropyridine derivatives and salts thereof represented by the general formula, ##STR1## which possess excellent calcium antagonist effect, hypotensive effect, platelets aggregation inhibitory...
5133958 Agent for nail, skin and hair care  
Agents and processes for the care of nails, skin and hair, for combatting progressive hair loss and for stimulating fresh hair growth of human hair, containing in the form to be administered daily...
5124356 Dermal uses of trans-retinoids for the treatment of photoaging  
The dermal use of non-irritating retinoids such as the esters and amides of 13-cis and 13-trans-retinoic acid for effecting the reduction and reversal of photoaging and skin cancer is disclosed.
5120746 Amine derivatives, salts thereof, process for preparing the same and an anti-ulcer agent containing the same  
This invention relates to amine derivatives and salts thereof. These compounds have an anti-ulcer activity which is effective to human beings and animals. This disclosure relates to such compound,...
5118683 Esters of 4-hydroxy-1,3-benzenedimethanol and compositions and methods employing such compounds  
Compounds of the formula I ##STR1## wherein R 5 represents C 1 to C 6 -alkyl or the group --(CH 2 ) n --Z--(CH 2 ) m --Ar; Z represents O, S or --CH 2 --; n represents an integer of 1...
5084466 Novel carboxamide pyridine compounds which have useful pharmaceutical utility  
Novel carboxamides and sulfonamides are described having of the formula R 1 --A--(W) a --X--(CH 2 ) b --(Y) c --B--Z--COOR (I), in which R 1 , A, W, X, Y, B, Z, R, a, b and c are as provided...
5071860 Insecticidally active substituted heteroaryl phenyl ethers  
Insecticidally active substituted heteroaryl phenyl ethers of the formula ##STR1## in which Het represents an optionally substituted heteroaromatic radical, X represents O, S, --CH 2 --,...
5055469 Quaternary pyridinium salts useful for ulcer treatment  
There are provided quaternary ammonium compounds of the formula: ##STR1## wherein R 1 and R 2 , each independently represents a hydrogen atom, a C 1 to C 8 lower alkyl or alkenyl group, or C 3 ...
5049584 Dermal uses of cis-retinoids for the treatment of cancer  
The dermal use of non-irritating retinoids such as the esters and amides of 13-cis and 13-trans-retinoic acid for effecting the reduction and reversal of photoaging and skin cancer is disclosed.
5049571 1-nitro-2,2-diaminoethylene derivatives  
There are disclosed novel 1-nitro-2,2-diaminoethylene derivatives of formula I ##STR1## wherein X is chlorine, fluorine, unsubstituted or halogen-substituted C 1 -C 5 alkyl; unsubstituted or...
5047430 Amide compounds, their production and use  
A compound is provided which has the formula ##STR1## wherein m is an integer of 1 to 3; n is an integer of 1 or 2; p is an integer of 1 or 2; q is an integer of 1 to 6; x is an integer...
5037839 Pyridine-2,4-and -2,5-dicarboxylic acid amides and medicaments based on these compounds  
The invention relates to pyridine-2,4- and -2,5-dicarboxylic acid derivatives of the formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and X have the meanings given, a process for the preparation...
Matches 151 - 200 out of 300 < 1 2 3 4 5 6 >