Patents in Class 514/348

Matches 1 - 50 out of 216

1 2 3 4 5 >

Match	Document	Document Title
1	8183266	Methods The invention relates to the novel chemical compounds of the formula (I): (I) in free or salt form, its use in the treatment of NET and/or SERT mediated conditions, e.g., depression, vasomotor...
2	8163781	Bi-aryl aminotetralines The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1-R5, A, B, Q, W, and X are defined in the detailed description and...
3	8158654	Pyridine non-classical cannabinoid compounds and related methods of use Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.
4	8138166	Method to induce fatty liver in animal The present invention discloses a method to induce fatty liver in an animal. The steps of the method comprise: feeding an animal with a high calorie diet, and injecting a mitochondrial inhibitor...
5	8097624	Cycloalkyl derivatives of 3-hydroxy-4-pyridinones The present invention provides an cycloalkyl derivative of 3-hydroxy-4-pyridinone which is useful for the chelation of metal ions such as iron. Its preparation and use is described. In particular,...
6	8067444	Pyridoxamine for the treatment of diabetic intermediaries and post-amadori inhibition The present invention provides pharmaceutical compositions comprising dosage units of pyridoxamine, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier, and...
7	8026261	Fluorinated derivatives of deferiprone The present invention relates to novel derivatives of deferiprone. In particular, the present invention relates to fluorinated derivatives of deferiprone or pharmaceutically acceptable salts...
8	7989478	Cinnamoyl compound and use of the same The present invention relates to a cinnamoyl compound represented by the formula (I):
9	7973060	Fab I inhibitor and process for preparing same A compound which is effective for inhibiting Fab I, and a method for treating a bacterial infection.
10	7951822	1,3-dihydroisobenzofuran derivatives The object is to provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; ...
11	7919509	2-oxochromene derivatives To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; ...
12	7906536	Processes for the preparation of 3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide This invention is directed generally to processes for the preparation of compounds of Formula I: wherein R2, R3, R4, R5, X1, X2, X3, X4, X5, X6 are as defined in the specification.
13	7897624	Pyridone sulfonamides and pyridone sulfamides as MEK inhibitors This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N′-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment o...
14	7868026	Therapeutic compounds The present invention provides compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, methods for their preparation, methods for their use, and pharmaceutical...
15	7850955	Gelling agent Gelling agents which contain a specific N-acylamino acid monoamide monoalkyl ester have a melting temperature of about 100° C., are capable of solidifying a wide variety of oily base materials ...
16	7723364	N-[2-(2-pyridinyl) ethyl]benzamide compounds and their use as fungicides Compound of general formula (I): Process for preparing this compound.Fungicidal composition comprising a compound of general formula (I).Method for treating plants by applying a compound of general...
17	7714002	Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions The present invention provides novel urea mimics and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, W,...
18	7696219	Method and composition for supplementation of nutritional deficiences in renal patients The present invention relates to compositions and methods for treating the nutritional deficiencies observed in patients suffering from renal disease and associated disorders. Specifically, the...
19	7687485	Formulation for menopausal women The present disclosure relates to novel compositions which provide improved nutritional support for premenopausal and menopausal women and/or relief from symptoms associated with menopause, as well...
20	7687500	Substituted oxetanes, method of making, and method of use thereof Oxetane-containing nucleosides, particularly non-reducing psiconucleoside oxetanes are described herein. Therapeutic application of these oxetane compounds toward the treatment of nucleoside analog...
21	7658943	Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment The invention described herein relates to a pharmaceutical composition containing vinorelbine as an active ingredient which is suitable for encapsulation in soft capsules. The liquid oral...
22	7629363	Diaryl substituted pyridinones Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3/R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions...
23	7585883	Substituted pyridines and their uses The present invention is directed to substituted pyridines, methods for their preparation and methods for their use in the treatment and/or prevention of mast cell related conditions.
24	7547713	O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives The present invention relates to the o-pyridinequinone disubstituted derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the...
25	7538126	Crystalline forms of valdecoxib The present invention relates to novel crystalline forms of valdecoxib, to processes for their preparation and to pharmaceutical compositions containing them.
26	7446117	Cox-2 inhibiting pyridine derivatives Compounds of formula (I) or pharmaceutically acceptable salts thereof are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever and inflammation of a variety...
27	7410985	Cycloalkyl derivatives of 3-hydroxy-4-pyridinones The present invention provides an cycloalkyl derivative of 3-hydroxy-4-pyridinone which is useful for the chelation of metal ions such as iron. Its preparation and use is described. In particular,...
28	7320993	Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents The invention relates to new pyridylalkane, alkene, and alkine acid amides substituted with an aryl and/or heteroaryl residue according to the general formula (I), with a saturated or one or...
29	7199101	Gelling agent for oil A gelling agent for an oil, which contains at least one compound (A) and at least one compound (B), and a gel composition containing the gelling agent and an oil: wherein R1 is a straight chain or...
30	7196105	Treatment of human multiple myeloma by curcumin All multiple myeloma cell lines examined showed constitutively active IκB kinase (IKK), IκBα phosphorylation and constitutively active NF-κB. Curcumin, a chemopreventive agent, suppressed con...
31	7183278	Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component Disclosed are novel compounds useful for the control of harmful organisms, harmful organism control agents using the same, and processes for producing the novel compounds. The useful novel...
32	7173055	Pyrazolecarboxamide and pyrazolethioamide as fungicide Novel pyraole derivatives of formula (I), wherein: X is oxygen or sufu, R1 is C1–C3alkyl, C1–C3haloalkyl, C1–C3alkoxy-C1–C3alkyl or C1–C3haloalkoxy-C1–C3alkyl; R2 is C1–C3haloalkyl; and R3 is hal...
33	7122563	Derivatives of 4-demethylpenclomedine, use thereof and preparation thereof Thiocarbonate and thiocarbamate derivatives of 4-demethylpenclomedine are provided along with pharmaceutical compositions containing them and use for treating cancer. A method for preparing the...
34	7074813	Substituted N′-(arylcarbonyl)-benzhydrazides, N′-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof The present invention is directed to substituted N′-(arylcarbonyl)-benzhydrazides, N′-(arylcarbonyl)-benzylidene-hydrazides and analogs thereof, represented by the Formulae I and II: wherein Ar1...
35	7067540	Substituted pyridinones Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions...
36	7049328	Use for deferiprone A method of treating iron induced cardiac disease in a patient with iron overload, such as in thalassemia or the like comprising administering to the patient a therapeutically effective amount of...
37	7026338	Pharmaceutical nitrones Pharmaceutical nitrone comprise condensates of an N-hydroxylamine and a physiological aldehyde, providing improved delivery and absorption, enhanced stability and reduced toxicity. Preferred...
38	7015237	Pyridine matrix metalloproteinase inhibitors Selective MMP-13 inhibitors are pyridine derivatives of the formula or a pharmaceutically acceptable salt thereof, wherein: R1 and R2 independently are hydrogen, halo, hydroxy, C1–C6 alkyl, C...
39	7008950	Benzofurans as suppressors of neurodegeneration A compound of the formula: wherein R1 and R2 each is H or a hydrocarbon group which may be substituted, or R1 and R2 form a 3- to 8-membered carbo or heterocyclic ring which may be substituted; R3...
40	6995166	Method and composition for supplementation of nutritional deficiencies in renal patients The present invention relates to compositions and methods for treating the nutritional deficiencies observed in patients suffering from renal disease and associated disorders. Specifically, the...
41	6974827	Phenyl substituted 4-hydroxy tetrahydroxypyridone The present invention relates to novel compounds of the formula (I) in which W, X, Y, Z, G, A, B, Q1, Q2 and Dare each as defined in the description, to a plurality of processes for their...
42	6967211	Remedial agent for chronic articular rheumatism The present invention relates to an excellent remedial agent for chronic rheumatoid arthritis, comprising an aminostilbazole derivative represented by the following formula [1] or a salt thereof as...
43	6946479	N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones Compounds of Formula (I) are effective in the treatment of a microbial infection.
44	6930117	N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones Compounds of Formula (I) are effective in the treatment of a microbial infection.
45	6900180	Pharmaceutical compositions for alleviating discomfort The invention relates to products for complete nutrition of infants or diseased or elderly persons. The products are characterized by increased levels of folic acid, vitamin B6 and vitamin B12 or...
46	6762178	Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors Hydroxamic acids having the formula are useful in treating disease conditions mediated by TNF-α, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, ...
47	6756392	Nicotinamide derivatives useful as PDE4 inhibitors The invention relates to nicotinamide derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The...
48	6747048	Pyridine-based thyroid receptor ligands Novel pyridine-based thyroid receptor ligands are provided which have the general formula I wherein:X is oxygen (—O—), sulfur (—S—), sulfoxide (—S(O)—), sulfonyl (—SO2—), CR8R8 or NR8;Y is —NR8, ...
49	6740668	Methods for inhibiting diabetic complications The instant invention provides compositions and methods for modeling post-Amadori AGE formation and the identification and characterization of effective inhibitors of post-Amadori AGE formation,...
50	6734143	2-methoxyimino-2(pyridinyloxymethyl)phenyl acetamides useful as fungicides The present invention provides 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides according to formula (I) as well as their use as fungicidal compounds.

Matches 1 - 50 out of 216

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