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9040082 Compositions and methods for treatment of chronic fatigue  
Pharmaceutical compositions and methods for the treatment of chronic fatigue in human patients comprising a central nervous system (CNS) stimulant in a daily low-dosage amount in combination with...
9034943 Salts of dehydroacetic acid as a pyrithione stabilizer in plastics  
The invention provides a method for preventing discoloration of pyrithione-containing materials, in particular plastic materials or other material such as paints, coatings, adhesives or textiles...
9028878 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses  
Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating natural surfaces that contain bacterial biofilm, including unexpected synergy or...
9028854 Pesticidal composition  
A pesticidal composition comprising 4-phenoxyphenyl 2-(2-pyridyloxy)propyl ether; a hydrophobic organic solvent capable of dissolving 0.1-fold by weight of 4-phenoxyphenyl 2-(2-pyridyloxy)propyl...
9029322 Compounds for enhancing p21 expression and methods of use thereof  
The present invention relates to a method for identifying a drug candidate for enhancing expression of p21cip1/waf1 in a human patient suffering from a medical condition that can be treated by...
9012494 Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors  
The N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is 1 or 2;L represents a C1-3alkyl linker optionally substituted with...
9000013 Application methods to rapidly alter disease and injury states using molecular transport of B6  
The present invention discloses methods of application employing B51B6 vitamins in molecular transport creams or gels to deliver B6 in a high dose to bring about therapeutic ways in human or...
8969347 Compounds and methods for treating inflammatory and fibrotic disorders  
Disclosed are compounds and methods for treating inflammatory and fibrotic disorders, including methods of modulating a stress activated protein kinase (SAPK) system with an active compound,...
8969390 Composition containing sorbitan monocaprylate and antimicrobial substances  
The invention relates to liquid compositions which contain a) from 40 to 99.9% by weight of sorbitan monocaprylate and b) from 0.1 to 60% by weight of one or more antimicrobial substances selected...
8962661 Fungicidal composition and method for controlling plant diseases  
To provide a fungicidal composition having stable and high fungicidal effects against cultivated crops infected with plant diseases resulting from plant diseases. A fungicidal composition...
8951934 Active compound combinations  
The invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a compound of formula (I) and at least one further respiratory chain...
8927549 Adamantyl benzamide derivatives  
Embodiments of the present invention provide adamantyl benzamide derivatives and pharmaceutical compositions comprising adamantyl benzamide derivatives. Methods of use of such compounds and...
8911795 Compositions comprising dihydroavenanthramide D and climbazole as cosmetic and pharmaceutical compositions for alleviating itching  
Compositions comprising dihydroavenanthramide D and climbazole; and, cosmetics or pharmaceutical end products comprising the compositions, useful for treating skin and/or hair.
8901154 High concentration topical insecticides containing pyrethroids  
A topical insecticide preparation is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. The topical insecticide contains a...
8883131 Composition for the treatment of hair loss and baldness  
A synergistic composition, or the use of that composition in the manufacture of a medicament, or a method of treatment including the use of that composition, for the treatment of hair loss and...
8871806 Methods for preventing flea allergy dermatitis in companion animals  
Methods for reducing the incidence of flea allergy dermatitis (FAD) in a companion animal are disclosed, the methods directed to inhibiting blood feeding by ectoparasites on a companion animal....
8865742 Intermediate compounds and processes for the preparation of quinoline derivatives such as Laquinimod sodium  
The present invention relates to processes for the preparation of quinoline-3-carboxamide derivatives, such as sodium 5-chloro-3-(ethylphenylcarbamoyl)-1-methyl-2-oxo-1,2-dihydro quinolin-4-olate...
8859573 Pyrimidinone and pyridinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2  
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases...
8846722 Animal parasite-control method using insect growth regulators  
Methods and formulations for treating animal ectoparasites, effective against parasites such as fleas and ticks are provided. The methods comprise topically co-administering a non-mobile insect...
8846074 Sublingual films  
The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders...
8835439 Pharmaceutical composition containing (2R)-methyl-1-3-[2-(3-pyridinyloxy)ethoxy]-2-pyrazinylpiperazine L-malate for treatment of serotonin-related diseases  
The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. In one aspect, the invention relates to a process for...
8809311 Nutritional supplements  
A process for improving the health of a subject, the process comprising orally administering a composition comprising hydroxytyrosol to the subject to provide the subject with a daily dose of...
8809374 Spot-on pesticide composition  
A spot-on pesticide composition for animals, specifically mammals, including dogs and cats, which composition comprises a combination of active components, including fipronil and a pyrethroid, and...
8809375 Spot-on pesticide composition  
A spot-on pesticide composition for animals, specifically mammals, including dogs and cats, which composition comprises a combination of active components, including fipronil and a pyrethroid, and...
8802720 Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals  
The present invention relates to compounds of the formula I, wherein A, Y, Z, R3 to R6, R20 to R22 and R50 have the meanings indicated in the claims, which are valuable pharmaceutical active...
8795700 Pyriproxyfen compositions  
New pesticidal compositions comprising pyriproxyfen and methyl esters of C16-C18 fatty acids and having low volatile organic compound (VOC) content are provided. Methods of use and ready-to-use...
8795630 Butyrylcholinesterase ligands as diagnostic tools and treatment for diseases of the nervous system  
Compounds useful for the early diagnosis of malignant tumors, multiple sclerosis, and especially Alzheimer's Disease and related dementias; especially compounds of Formula (I) wherein R1 is...
8778953 Inhibitors of P38 map kinase  
Compounds of formula (I) are p38 MAP kinase inhibitors useful for the treatment of autoimmune and inflammatory diseases: wherein: G is —N═ or —CH═; D is an optionally substituted divalent mono- or...
8765726 Use of pyridone derivatives in the prevention or treatment of tissue or organ toxicity induced by cytotoxic agents and radiation  
The present invention is directed to a novel use of pyridone derivatives such as pirfenidone for the prevention and treatment of damages to tissues or organs induced by various cytotoxic agents,...
8759400 Histone deacetylase inhibitors for enhancing activity of antifungal agents  
The present invention relates to compositions and methods to selectively treat fungal infection. More particularly, this invention relates to compositions and methods for selectively enhancing...
8753679 Capsule formulation of pirfenidone and pharmaceutically acceptable excipients  
A capsule formulation of pirfenidone is provided that includes pharmaceutically acceptable excipients. In one embodiment, this capsule formulation is capable of sustaining desirable...
8754109 Pirfenidone therapy and inducers of cytochrome P450  
The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
8748462 Spirocyclic GPR40 modulators  
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula IA, IB, I′A or I′B: where the definitions of...
8748339 Synergistic fungicidal mixtures  
The present invention relates to a composition, comprising a 5-amino-3-oxo-2,3-dihydro-pyrazole of the formula I as defined in the claims and the description and at least one active compound II...
8748620 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Thyroid hormone β receptor agonist
 
Provided is a heterocyclic derivative showing a thyroid hormone β receptor agonist action, which is effective for the prophylaxis or treatment of the diseases relating to the action. A compound...
8741936 Method of modulating stress-activated protein kinase system  
Disclosed are methods of modulating a stress activated protein kinase (SAPK) system with an active compound, wherein the active compound exhibits low potency for inhibition of at least one p38...
8741927 Production method of intermediate compound for synthesizing medicament  
The present invention relates to a novel method for preparing a compound of formula (2) as the intermediate, which can be effectively used for preparation of a compound of formula (1) exhibiting...
8710053 Plant disease control composition and its use  
A plant disease control composition comprising a carboxamide compound represented by following formula (I), wherein R1 represents a hydrogen atom or a methyl group, and R2 represents a methyl...
8703802 Process for the preparation of aryl substituted olefinic amines  
An improved process for the preparation of aryl substituted olefinic amines such as (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2- amine and...
8691851 Lanthanide metal complexes useful in treating cancer  
The present invention relates to a compound of formula (I). Provided is also a method of killing a cell that comprises administering the compound of formula (I). Provided is also a method of...
8685955 Neuroprotective iron chelators and pharmaceutical compositions comprising them  
Novel iron chelators exhibiting neuroprotective and good transport properties are useful in iron chelation therapy for treatment of a disease, disorder or condition associated with iron overload...
8680123 Substituted N-aryl pyridinones  
Disclosed herein are substituted N-Aryl pyridinone fibrotic inhibitors and/or collagen infiltration modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof,...
8673901 Potassium channel blockers  
The present invention provides a compound of formula (I) or its salts or pharmaceutically acceptable derivatives thereof wherein X1, R1, R2, R3, R4, and R5 are defined as set forth in the...
8669209 Process for preparing soluble granules of salts of pyridine containing carboxylic acids  
Soluble granule formulations of amine salts of pyridine containing carboxylic acids with improved handling properties are provided by an improved process in which the pyridine containing...
8648098 Pirfenidone therapy and inducers of cytochrome P450  
The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
8642629 Naphthylacetic acids  
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein W, X, Y, and R1-R7 are defined in the detailed description and claims....
8609701 Pirfenidone treatment for patients with atypical liver function  
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include...
8609637 Prodrugs of 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-(1H)-one and derivatives thereof  
A prodrug can have a structure of Formula 10 or derivative thereof or stereoisomer thereof or pharmaceutically acceptable salt thereof. The prodrug can be included in a pharmaceutical composition...
8604063 Chemical molecules that inhibit the slicing mechanism for treating diseases resulting from splicing anomalies  
The present invention relates to a compound of one of the formulas I to XXI; a pharmaceutical composition comprising at least one such compound; and the use of at least one such compound in...
8603945 Methods and compositions for providing salicyclic acid-independent pathogen resistance in plants  
This disclosure relates to methods and compositions for modulating disease resistance in plants and transgenic plants.