Patents in Class 514/340

Matches 1 - 50 out of 889

Match	Document	Document Title
1	8440702	1,3-oxazolidin -2-one derivatives useful as CETP inhibitors Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol,...
2	8440700	Substituted aryloxazoles and their use The present application relates to novel substituted aryloxazole derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for...
3	8440701	Trisubstituted 1,2,4 triazoles The present invention relates to substituted 1-(alkyl)-3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical...
4	8435999	Compositions and methods for controlling nematodes Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.
5	8431606	Medicament for treating schizophrenia comprising cilostazol The invention relates to a medicament for preventing and/or treating schizophrenia which comprises as an active ingredient cilostazol or a pharmaceutically acceptable salt thereof.
6	8420676	Oxazolidinone derivatives The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone...
7	8415359	Phenylpyrrole derivative The present invention relates to a compound or a pharmacologically acceptable salt thereof having superior glucokinase activating activity, and is a compound represented by general formula (I), or...
8	8410145	Insecticidal compounds A compound of formula (I): wherein A1, A2, A3, A4, G1, R1, R2, R3 and R4 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes and...
9	8404676	Oxadiazole diaryl compounds The invention relates to compounds of formula (I): wherein R1, R2, Ra, Rb, Rc and W, have the meanings given in claim 16. The compounds are useful e.g. in the treatment of autoimmune disorders,...
10	8404722	Oxazole compounds compositions and methods of use The present invention relates generally to compounds represented in Formula (I), pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.
11	8404726	Activating agent for peroxisome proliferator activated receptor δ A compound represented by the following general formula (II) or a salt thereof is used as an activator of PPARδ. wherein Ga is O, CH2 or the like;Aa is thiazole, oxazole, or thiophene, which can ...
12	8399493	Pyridinone derivatives and their use as positive allosteric modulators of mGluR2-receptors The present invention relates to methods for treating or controlling schizophrenia in a mammal using compounds having the Formula (I), wherein M1 and M2 are defined in the application.
13	8399494	2,5-disubstituted phenyl carboxamide orexin receptor antagonists The present invention is directed to 2,5-disubstituted phenyl carboxamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological...
14	8399492	Pyridine derivatives as sphingosine 1-phosphate (S1P) receptor modulators The present invention relates to novel pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of...
15	8394837	2,3,4,6-substituted pyridyl derivative compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease The present invention is directed to 2,3,4,6-substituted pyridyl derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the...
16	8389549	Substituted pyridines useful for treating pain A compound of Formula: (I) or a pharmaceutically acceptable derivative thereof, where Ar1, Ar2, X, R3, and m are as disclosed herein. Compounds of Formulae (I)-(V) and pharmaceutically acceptable...
17	8389546	Compounds for modulating TRPV3 function The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
18	8389550	Isoxazoles / O-pyridines with ethyl and ethenyl linker The present invention is concerned with novel isoxazole-pyridines of formula I wherein R1, R2, R3 and L are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The...
19	8383660	Dibenzyl amine compounds and derivatives Dibenzyl amine compounds and derivatives of Formula I, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high...
20	8377942	Isoxazolines derivatives and their use as pesticide Novel isoxazoline compounds, compositions containing the compounds and methods for making the compounds are disclosed. The compounds and compositions have pesticidal properties and are suitable for...
21	8377971	Non-flushing niacin analogues, and methods of use thereof One aspect of the present invention relates to substituted pyridines and pharmaceutically acceptable salts thereof that are active against a range of mammalian maladies. Another aspect of the...
22	8377938	Phenoxypyridine derivative salts and crystals thereof, and process for preparing the same The invention provides acid addition salts of the compounds represented by formula (1) or (2), or crystals thereof, and processes for preparing the same. The salts or crystals have HGFR inhibitory...
23	8372807	Methods of modulating uric acid levels Described herein are compounds useful in the reduction of blood uric acid levels, formulations containing them and methods of making and using them. In some embodiments, a compound disclosed herein...
24	8372867	Insecticidal aryl isoxazoline derivatives The present invention relates to novel aryl isoxazoline derivatives having excellent insecticidal activity as insecticides and represented by the formula: and their use as insecticides and acarizides.
25	8357703	Pyridines The present invention is concerned with novel isoxazoles of formula I wherein X, R1, R2, R3 and R4 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The...
26	8343952	Prolyl hydroxylase inhibitors and methods of use The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter a...
27	8344002	Compound having β-secretase inhibitory activity A novel compound represented by the formula (1) below which has β-secretase inhibitory activity, its pharmaceutically acceptable salt or a prodrug thereof. wherein Ar is a substituted or ...
28	8329706	Oxazolidinone derivatives The present invention relates to oxazolidinone derivatives of formula (I) wherein Y, R3 and R4 are as described in the description, to their preparation, to pharmaceutically acceptable salts...
29	8324226	Therapeutic oxy-phenyl-aryl compounds and their use The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain oxy phenyl aryl compounds (referred to herein as OPA compounds), as described...
30	8318761	Substituted arylsulfonamides as antiviral agents The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of...
31	8318776	Pyridine compound, pesticidal composition and method of controlling pests A pyridine compound represented by the following general formula (1); the pyridine compound in which R1 is a C1-C3 fluoroalkyl group or a C1-C3 fluoroalkoxy group; the pyridine compound in which R2...
32	8318792	Therapeutic agent for amyotrophic lateral sclerosis A method for treating amyotrophic lateral sclerosis is disclosed wherein a compound having xanthine dehydrogenase inhibiting activity is administered.
33	8299076	Crystalline forms of 2-(2-flouro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide Disclosed are crystalline forms of 2-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimet hyl-6-oxo-1,6-dihydropyridine-3-carboxamide useful in the treatment of hyperproliferative diseases,...
34	8299074	P38 MAP kinase inhibitors The present disclosure relates to compounds of formula (I): which are inhibitors of p38 mitogen-activated protein kinase enzymes, particularly the alpha and gamma kinase sub-types thereof, and...
35	8299082	1,2,4-triazolylaminoaryl (heteroaryl) sulfonamide derivatives 1,2,4-Triazolylaminoaryl(heteroaryl)sulfonamide derivatives of formula (I), pharmaceutically acceptable salts thereof, processes for the manufacture of...
36	8299073	P38 MAP kinase inhibitors The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, including all stereoisomers, tautomers and isotopic derivatives thereof, which are inhibitors of...
37	8293770	Pyrrolidine derivatives as NK-3 receptor antagonists The present invention relates to a compound of formula I wherein Ar1, Ar2, R1, R2, R3, n, o, and p are as described hereinor to a pharmaceutically active salt, to all stereoisomeric forms,...
38	8293771	p38 MAP kinase inhibitors There is provided a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, including all tautomers thereof, compositions comprising the same, use of said compound and...
39	8293748	p38 MAP kinase inhibitors There are provided inter alia compounds of formula (I) wherein R1, Ar, L, X, R3 and Q are as defined in the specification for use in therapy, especially in the treatment of inflammatory diseases.
40	8288371	Ortho pyrrolidine, benzyl-substituted heterocycle CCR1 antagonists for autoimmune diseases and inflammation Compounds of the formula are disclosed. The compounds are CCR1 antagonists which are useful for the treatment and prevention of inflammatory and autoimmune diseases. Other embodiments are also...
41	8288403	Heterocyclic gamma secretase modulators The invention relates to methods for the treatment of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct...
42	8278317	Potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.
43	8278334	Cyclic amine BACE-1 inhibitors having a benzamide substituent Disclosed are compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1 is R is —C(O)—N(R27)(R28) or and the remaining variables are as defined in the spe...
44	8247431	Heterocyclic hydrazide compound and pesticidal use of the same A hydrazide compound represented by the formula (I), an N-oxide thereof or suitable salt thereof: has excellent pesticidal activity.
45	8242103	Sulphamides for treatment of cancer Bridged bicyclic sulphamides of formula (I) are disclosed for treatment of cancer.
46	8242118	Arylsulfonamide derivatives for use as CCR3 antagonists in the treatment of inflammatory and immunological disorders The present invention relates to a sulfonamide derivative which is useful as an active ingredient of pharmaceutical preparations. The sulfonamide derivatives of the present invention have CCR3 (CC...
47	8231888	Isoxazolines for controlling invertebrate pests Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A1, A2, A3, A4, A5 and A6 are independently selected from the group consisting...
48	8232302	Thiazoles and oxazoles useful as modulators of ATP-binding cassette transporters The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof...
49	8227461	Isoxazoles The present invention is concerned with novel isoxazole derivatives of formula I wherein X, R1, R2, R3, R4 and R5 are as described herein, as well as pharmaceutically acceptable salts and esters...
50	8222246	Substituted isoxazoles The present invention is concerned with novel hydroxy-methyl isoxazole derivatives of formula I wherein R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts and...

Matches 1 - 50 out of 889

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