|
Match
|
Document |
Document Title |
|
|
5026717 |
2-imino-6-polyfluoroalkoxybenzothiazole derivatives, and pharmaceutical compositions containing them
Compounds of formula: ##STR1## and their salts, in which R 1 represents polyfluoroalkoxy, and R 2 represents alkyl, alkenyl (3-6 C), [cycloalkyl (3-6 C)]-alkyl, carbamoylalkyl,...
|
|
|
5025024 |
Therapeutically active fluoro-substituted compound
The novel compound 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]sulfinyl]-1H-benz
imidazole and physiologically acceptable salts thereof as well as intermediates, pharmaceutical compositions...
|
|
|
5021420 |
Derivatives of (AZA)naphthalenesultam, their preparation and compositions containing them
This invention relates to a compound ##STR1## in which R 1 represents a 1,2,3,6-tetrahydro-1-pyridyl radical substituted in the 4-position by (a) a phenyl radical, (b) a phenyl radical...
|
|
|
5021433 |
Novel pharmacological compounds
Novel compounds of the formula ##STR1## pharmaceutical compositions containing such compounds as active ingredient with gastric and inhibiting effects.
|
|
|
5021446 |
Pyrazole compounds, insecticidal and acaricidal compositions and use
There are disclosed a pyrazole compound represented by the formula, ##STR1## wherein the substituents of R 1 to R 8 and the symbol Z have the specified meanings as described in the text, an...
|
|
|
5019584 |
Therapeutically active chloro substituted benzimidazole
5-Chloro-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-
benzimidazole and physiologically acceptable salts thereof as well as an intermediate, pharmaceutical compositions containing such...
|
|
|
5015633 |
Method for inhibiting loss of cognitive functions employing an ace inhibitor
A method is provided for inhibiting loss of cognitive function, including memory, which may or may not be associated with Alzhemier's disease, in a mammalian species by administering an ACE...
|
|
|
5013743 |
Selective antibacterial agent against campytobacter
The compound represented by the formula; ##STR1## [wherein R 1 stands for hydrogen, methoxy or trifluoromethyl; R 2 and R 3 , being the same or different from each other, stand for hydrogen or...
|
|
|
5010087 |
Tricyclic compounds and TXA.sub.2 antagonistic compositions thereof
Novel tricyclic compounds having a TXA 2 -antagonizing activity represented by formula (I): ##STR1## which strongly antagonize an action of thromboxane A 2 and are expected to have preventive and...
|
|
|
5008278 |
Therapeutically active compound and a process for its preparation
The novel compound 5-fluoro-2[[(4-cyclopropylmethoxy-2-pyridinyl) methyl]sulfinyl]-1H-benzimidazole and physiologically acceptable salts thereof as well as intermediates, pharmaceutical...
|
|
|
5008277 |
N-[(alpha-perhaloalkylbenzyloxy)pyridyl]N'-benzoylurea insecticides
N-[(Alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoylurea compounds of the following structural formula are useful insecticides: ##STR1## in which R A is selected from the group consisting of...
|
|
|
5006541 |
Antiallergy and antiinflammatory agents
Compounds of the formula ##STR1## where Y is alkyl, aryl or heterocyclic, n is 1-7, R is hydrogen, alkyl, aralkyl or carboxymethyl, R 1 is acetoxy, thiophenoxy, hydrogen, halo, alkyl, alkoxy or...
|
|
|
5002945 |
Imidazole derivatives
Novel imidazole of the formula: ##STR1## wherein Ring A is pyridyl group or a substituted pyridyl group; Ring B is phenyl group or a substituted phenyl group; R 1 and R 2 are hydrogen atom or are...
|
|
|
5002941 |
Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
Compounds comprising pyridyl and phenyl substituted pyrrolo[1,2-a]imidazole derivatives and pyridyl and phenyl substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing...
|
|
|
5001137 |
Pyridine compounds and pharmaceutical use thereof
A novel pyridine compound of the formula ##STR1## wherein each symbol is as defined in the specification, or a salt thereof which exhibit inhibitory activity or prolylendopeptidase and a...
|
|
|
4999361 |
Trisubstituted amines, pharmacologically acceptable salts thereof and pharmaceutical compositions containing them
The present invention provides compounds of the general formula ##STR1## wherein R 1 is a hydrogen atom, a straight-chained or branched C 1 -C 12 -alkyl radical, a C 3 -C 7 -cycloalkyl...
|
|
|
4996217 |
Pyridyl-substituted imidazoles, compositions containing same and methods of use thereof
Novel imidazole of the formula: ##STR1## wherein Ring A is pyridyl group or a substituted pyridyl group; Ring B is phenyl group or a substituted phenyl group; R 1 and R 2 are hydrogen atom or are...
|
|
|
4992453 |
Certain thioimidate and amidine insecticides
Insecticidal compounds having the formula ##STR1## in which R is an optionally substituted aryl moiety; R 2 is an optionally substituted alkyl, cycloalkyl or alkenyl moiety, X is sulfur, amino or...
|
|
|
4988689 |
((Pharmacologically active bicyclic heterocyclic)methyl and -heteroatom) substituted hexahydro-1H-azepines and pyrrolidines
[(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines and their pharmaceutically acceptable acid addition salts having anti-histaminic properties,...
|
|
|
4987146 |
N-hetaryl imidazole derivatives
N-hetaryl imidazole derivatives of general Formula I ##STR1## are disclosed in which Het represents an optionally substituted monocyclic or bicyclic heteroaromate, R 3 represents hydrogen, a...
|
|
|
4981861 |
Tricyclic imidazole derivatives
Tricyclic imidazole derivatives of formula I ##STR1## wherein one of R 1 and R 3 is lower alkyl and the other is hydrogen or lower alkyl, R 2 is lower alkyl, n is the number 0 or 1, A is...
|
|
|
4981864 |
Method for inhibition of erythrocyte aggregation using anellated tricyclic compounds
The present invention is concerned with the use of compounds of the general formula: ##STR1## wherein R 1 is a phenyl radical of the general formula: ##STR2## or R 1 is a 5 or 6 membered...
|
|
|
4980345 |
Pyrazole compounds and use thereof
There are disclosed a pyrazole compound represented by the formula, ##STR1## wherein the substituents of R 1 to R 7 and the sumbol Z have the specified meanings as described in the text, an...
|
|
|
4980356 |
2-imino-6-polyfluoroalkoxybenzothiazole derivatives, and pharamaceutical compositions containing them and their treatment of medical conditions associated with the effects of glutamate
Compounds of formula: ##STR1## and their salts, in which R 1 represents polyfluoroalkoxy, and R 2 represents alkyl, alkenyl (3-6 C), [cycloalkyl (3-6 C)]-alkyl, carbamoylalkyl,...
|
|
|
4971985 |
Pyridylketoxime ether compound and pharmaceutical composition containing it
A pyridylketoxime ether compound of the formula: ##STR1## wherein Ar is a phenyl, naphthyl, or heterocyclic group unsubstituted or substituted by a C 1 -C 8 alkyl group, a C 1 -C 8 alkylamino...
|
|
|
4971981 |
Substituted dioxolan and dioxan derivatives useful as pesticides
Novel substituted 1,3-dioxolan and 1,4-dioxan derivatives of formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 , R 5 and R 6 each independently of the others represents hydrogen or C 1 -C 4 ...
|
|
|
4968805 |
Pyrazole derivatives and insecticidal fungicidal and miticidal compositions thereof
Disclosed herein are pyrazole derivatives which are represented by the following formula (I): ##STR1## wherein R 1 represents a C 1 -C 4 alkyl group or a benzyl group; R 2 represents a hydrogen...
|
|
|
4965269 |
Therapeutically active chloro substituted benzimidazoles
The novel compounds of the formula I ##STR1## wherein Cl is in 5 or 6 position and whereby R is the group --CH 2 OCOOR 1 , wherein R 1 is a straight or branched alkyl containing 1-6 carbon atoms...
|
|
|
4959376 |
1,4-benzodioxane derivatives
1,4-Benzodioxane derivatives represented by the following general formula: ##STR1## wherein p stands for an integer of 0-2, X and Y are same or different, and each represent a hydrogen atom; or a...
|
|
|
4959362 |
Pharmaceutical compositions containing certain ascorbic acid derivatives useful in the prophylaxis and treatment of disorders of the circulatory system
An ascorbic acid derivative of the formula: ##STR1## wherein R 1 is organic residue having molecular weight of from 15 to 700, R 2 is hydrogen or hydroxyl, R 3 is hydrogen, acyl, optionally...
|
|
|
4957928 |
Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
The invention relates to novel hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds of formula ##STR1## in which the variable R 1 , R 2 , R 3 , R 4 , R 5 , alk, X, Z, m, n and p, the...
|
|
|
4956369 |
2-dithioalkyl-dihydropyridines and pharmaceutical compositions containing them
Compounds of formula I ##STR1## wherein R 1 and R 3 , which are the same or different, are alkoxycarbonyl, acetyl, cyano, nitro, benzoyl or amino-carbonyl groups, R 2 is differently...
|
|
|
4954502 |
1-indolyalkyl-4-(substituted-pyridinyl)piperazines
A series of 1,4-disubstituted piperazine derivatives comprised of indol-3-ylalkyl and substituted pyridin-2-yl substituent groups. These compounds are useful as antidepressant agents.
|
|
|
4952592 |
1,4-dihydro 2,6-dimethyl 4-(2,3-methylenedioxyphenyl) 3-alkoxy carbonyl 5-[2-(substituted amino)ethoxy]carbonyl pyridine
1,4 dihydropyridines of general formula: ##STR1## in which: R 1 is a linear or branched C1-C4 alkyl group; R 2 is formyl or a C1-C2 alkyl group; R 3 is a 2-, 3-, 4-picolyl,...
|
|
|
4950676 |
Amino-esters of dihydropyridines, and their use as circulatory agents for treating ischaemic heart diseases
Circulation active compounds of the formula ##STR1## in which R 1 is phenyl or heterocyclyl substituted by nitro, trifluoromethyl or other radicals, R 2 is optionally substituted alkyl or...
|
|
|
4950677 |
Benzimidazole derivative compounds and method of making
A compound of the formula ##STR1## wherein R 1 -R 19 are as described in the specification. The present invention is concerned with benzimidazole derivatives, particularly benzimidazole-2-yl...
|
|
|
4943574 |
(1H-azol-1-ylmethyl) substituted benzotriazole derivatives and pharmaceutical compositions containing them
(1H-azol-1-ylmethyl)substituted benzotriazole derivatives, compositions containing the same, and methods of treating estrogen dependent disorders.
|
|
|
4937255 |
Disubstituted pyrroles
For inhibiting 3-hydroxy-3-methylglutaryl coenzyme A and cholesterol biosynthesis, the novel disubstituted pyrroles of the formula ##STR1## in which R 1 is aryl or heteroaryl, R 2 is...
|
|
|
4937258 |
Pyrrolo[1,2-c]imidazolone derivatives as PDE inhibitors
This invention relates to novel pyrrolo[1,2-c]imidazolones and their pharmaceutically acceptable salts. The compounds of the invention are PDE inhibitors with primarily cardiovascular effects...
|
|
|
4933338 |
Benzimidazolesulfonamides and their application as drugs
Benzimidazole-2-sulfonamide and imidazopyridine-2-sulfonamide derivatives corresponding to the general formula I: ##STR1## and their pharmaceutically acceptable salts, especially those of the...
|
|
|
4931448 |
Thiomidate insecticides
Insecticidal compounds having the formula ##STR1## in which R is an optionally substituted aryl moiety; R 2 is an optionally substituted alkyl, cycloalkyl or alkenyl moiety, X is sulfur, amino or...
|
|
|
4925854 |
Benzimidazole derivatives
Benzimidazole derivatives of general Formula I ##STR1## wherein R 1 and R 2 , being identical or different, each mean hydrogen or an optionally substituted hydrocarbon residue and X is oxygen...
|
|
|
4925853 |
Benzimidazoles as 5-lipoxygenase inhibitors
Compounds of the general formula I ##STR1## or pharmaceutically acceptable salts or solvates thereof, in which R 1 represents hydrogen or a lower alkyl group, R 2 represents hydrogen, a lower...
|
|
|
4923871 |
Certain 2,6-dimethyl-4-(pyrazolo[1,5a]-pyridin-3-yl)1,4-dihydro-pyridine-3,5-dic arboxylate derivatives and compositions containing same
This invention relates to new and useful 2,6-dimethyl-4-(pyrazolo[1,5-a]pyridin-3-yl)-1,4-dihydropyri
dine-3,5-dicar boxylate derivatives of the following formula: ##STR1## and pharmaceutically...
|
|
|
4920136 |
Substituted pyridylethanolamine livestock production promoters
For promoting livestock production, the novel substituted pyridylethanolamines of the formula ##STR1## in which R 1 represents CN, --COOR 8 or --CONR 9 R 10 , R 2 represents optionally...
|
|
|
4910195 |
Dihydropyridine derivatives
Dihydropyridine derivatives represented by formula (I): ##STR1## wherein R 1 , R 2 , R 3 and R 6 , which may be the same or different, each represents an alkyl group, a cycloalkyl group or an...
|
|
|
4904675 |
Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines
Compounds of the formula I ##STR1## wherein the groups A, R 1 , R 2 and R 3 are as defined in the specification, exhibit valuable pharmacological properties, especially as antifibrotic agents....
|
|
|
4904671 |
Dihydropyridine antiallergic and antiinflammatory agents
4-Aryl-2,6-disubstituted-3,5-dicarbamyl-1,4-dihydropyridines
and 4-Aryl-2,6-disubstituted-3-alkoxycarbonyl-5-carbamyl-1,4-dih
ydropyridines as antiallergy and antiinflammatory agents.
|
|
|
4900751 |
2-Pyridinyl-phenyl-sulphinyl-and-phenyl-thio-benzimidazoles having antiflammatory or gastic acid secretion inhibition activity
Compounds of formula I, ##STR1## in which A is a 5 or 6 membered, fully unsaturated, carbocyclic or heterocyclic ring, B is a 5 or 6 membered, fully unsaturated, nitrogen containing heterocyclic...
|
|
|
4900750 |
1.4-Dihydropyridines
This invention concerns compounds of formula ##STR1## or salts thereof, wherein: Ar is an optionally substituted aryl radical; R represents hydrogen or an optionally substituted alkyl, aralkyl,...
|