Matches 301 - 350 out of 469 < 1 2 3 4 5 6 7 8 9 10 >
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5252598 Labdane derivatives, a process for their preparation, and their use as medicaments  
The present invention relates to labdane-derivatives of the formula ##STR1## a process for their preparation and the use of these substances as medicaments, preferably as medicaments having a...
5246956 N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans having antithromboxane A.sub.2 activity  
The invention provides new imidazole containing alkoxyimino derivatives of tetrahydronaphthalene and chroman of general formula (I) ##STR1## wherein Z is --CH 2 --or--O--; m is an integer of 1...
5244653 Glycine anhydride dimethylol as a biocide and preservative  
The use of glycine anhydride dimethylol, also known as 1,4-bis(hydroxymethyl)-2,5-piperazinedione, comprising the formula ##STR1## to kill microorganisms present in or on a host substance and to...
5236935 Benzopyran derivatives and processes for the preparation thereof  
The present invention relates to novel benzopyran derivatives of formula (I) which have superior selectivity in the treatment of hypertension by lowering blood pressure with a relaxation activity...
5229401 Substituted pyridinylamino benzo[b]thiophene compounds  
This invention relates to substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzo[b]thiophenes and 1,2-benzisothiazoles of the formula ##STR1## wherein Q is S, N or NR 2 ; Y is...
5208222 4"-and 4'-alkylthio avermectin derivatives  
Avermectin derivatives are disclosed wherein the 4"-hydroxy group is replaced by a substituted alkylthio or acylthio group or an iodo group. These avermectin derivatives can be further derivatized...
5204357 Renin-inhibiting amino acid derivatives  
The invention relates to compounds of the formula I ##STR1## in which A represents a substituted thio-, sulfinyl- or sulfonyl-alkanoyl radical or a four- to eleven-membered heterocycle, B is an...
5194442 2,3,4,5-tetrahydro-1-benzoxepins, the use thereof and pharmaceutical products based on these compounds  
2,3,4,5-Tetrahydro-1-benzoxepins of the formula I ##STR1## with R 1 equaling, inter alia, H, alkyl, alkoxy, Hal, alkylsulfonyl, arylsulfonyl, R 2 equaling H, alkyl, alkoxy, OH, R 3 to R 6 H or...
5189045 Aminopiperidine indanyl and benzocyclobutene compounds  
The invention relates to new compounds of formula I: ##STR1## in which: m represents zero, 1, 2, 3 or 4, n and p represent zero, 1 or 2, W represents an oxygen atom, an --NH-- radical, or a...
5189047 2-Oxo-1,2-(dihydropyridyl)-2H-1-benzopyrans  
The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein Y, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , a and b are as defined in the...
5185350 Substituted pyridinylamino-1H-indoles,1H-indazoles,2H-indazoles, benzo (B)thiophenes and 1,2-benzisothiazoles  
This invention relates to substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzo[b]thiophenes and 1,2-benzisothiazoles of the formula ##STR1## wherein Q is S, N or NR 2 ; Y is...
5166212 Certain n-substituted butyramide derivatives  
Disclosed are compound of the formula ##STR1## wherein X and Y independently represent hydroxymethyl; cyano; carboxy; functionally modified carboxy selected from esterified carboxy, carbamoyl, and...
5166161 1,3-dicarbonyl compounds and their use  
3-Oxo-4-acyl or carbamyl-bicyclic aromatic and heterocyclic compounds as inhibitors of cyclooxygenase and lipoxygenase and useful as antiallergy and antiinflammatory agents.
5158943 Sulfur-containing heterocyclic compounds  
A sulfur-containing hetrocyclic compound of the formula (I) ##STR1## wherein the ring A is an optionally substituted benzene ring, R is a hydrogen atom or an optionally substituted hydrocarbon...
5143924 Oxodihydropyridyl chroman derivatives  
Novel chroman derivatives of the formula I ##STR1## in which R 1 to R 6 and Z have the meanings given in Patent Claim 1, and their salts show effects on the cardiovascular system and can be used...
5140031 Pyranyl cyanoguanidine derivatives  
Novel compounds having the formula ##STR1## wherein ##STR2## are disclosed. These compounds have potassium channel activating activity and are useful, for example, as cardiovascular agents,...
5128348 Bicyclo(3.1.0)hexane amines and bicyclo(4.1.0)-heptane amines as agricultural fungicides  
Certain hexane and heptane amines including geometric and stereoisomers, agricultural compositions containing them and their use as fungicides.
5118694 Benzopyran derivatives  
Compounds of the formula ##STR1## wherein R 1 is hydrogen, halogen, trifluoromethyl, nitro, cyano, lower alkyl, lower alkoxycarbonyl, lower alkylthio, lower alkylsulphonyl, lower alkanoyl, aroyl,...
5112855 Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds and compositions  
The invention relates to novel hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds of formula ##STR1## in which the variables R 1 , R 2 , R 3 , R 4 , R 5 , alk, X, Z, m, n and p, the...
5109010 Dibenzofuranyl substituted 1,5-dihydro-4-(N-methylhydroxylamino)-2H-pyrrol-2-ones  
Novel cyclic vinylogous N-hydroxy-N-methylureas are useful in the treatment of leukotriene mediated conditions such as asthma and rheumatoid arthritis.
5104888 Thiazolidine derivatives, their preparation and use  
Compounds of formula (I): ##STR1## (in which R 1 -R 7 are hydrogen or various organic groups, n is 1-10, Ar is an aromatic group, U is CH 2 or a carbon atom doubly bonded to either one of its...
5071871 Pharmaceutically useful benzo(β)pyranes and pyranopyridines  
New benz[b]pyranes and pyranopyridines of formula I, ##STR1## wherein the significances of substituents V, T, W, R 3 to R 5 , R 9 , R 10 , m, X, Y and Z are given in claim 1 and their N-oxides and...
5051421 Benzo-[b]thiophene derivatives  
Benzo[b]thiophene derivatives of formula ##STR1## their tautomers and salts, in which the index n is 0, 1 or 2, alk is lower alkylene, Ar is phenyl, naphthyl or a monocyclic, five- or six-membered...
5047414 2-(aminoalkylthio)methyl-1,4-dihydropyridine, a method for the preparation thereof and pharmaceutical compositions containing them  
Compounds of formula I, and pharmaceutical compositions containing compounds of formula I ##STR1## wherein: R 1 is: (a) COCH 3 , COC 6 H 5 , CN or NO 2 ; (b) COORa wherein Ra is hydrogen,...
5043352 Chroman derivatives for the treatment of depressive states  
A method of treatment of depressive states which comprises administering in mammals in need thereof an effective amount of a compound ##STR1## R 1 represents hydrogen, a halogen atom, a cyano...
5043344 Unsaturated N-benzopyranyllactams  
Compounds I ##STR1## where R 1 is H, alkyl, alkoxy, CO alkyl, COOH, carboxyalkyl, CONR 2 , CN, NO 2 , alkylsulfi(o)nyl, arylsulfi(i)-nyl; R 2 is H, OH, alkoxy, alkyl or alkylcarbonyl, R 3 /R 4 ...
5041444 Benzoxepin derivatives  
A benzoxepin derivative represented by the formula (I): ##STR1## wherein R represents a heterocyclyc group, and salts thereof; a process for production thereof comprising the steps of reducing an...
5036080 (D)-6-fluoro-2,3-dihydro-2',5-dioxo-spiro[4H-1-benzo pyran-4,4'-imidazolide]-2-carboxamide compounds  
Hydantoin derivatives of the formula ##STR1## wherein Ra and Rb are same or different, each being hydrogen atom, alkanoyl, substituted or none-substituted aroyl, heteroaroyl, alkoxycarbonyl,...
5032591 Pharmaceutical preparations  
A pharmaceutical product comprising a potassium channel activator antihypertensive agent and a β-blocker antihypertensive agent as a combined preparation for simultaneous, separate or sequential...
5021444 Thianaphthene derivatives  
Compounds of formula (I): ##STR1## (wherein n is 0 or 1, R 1 and R 2 are hydrogen or alkyl, one of A 1 and A 2 is --Z--Y and the other is --W--COOH, where W and Z are alkenylene or alkylene and...
5010087 Tricyclic compounds and TXA.sub.2 antagonistic compositions thereof  
Novel tricyclic compounds having a TXA 2 -antagonizing activity represented by formula (I): ##STR1## which strongly antagonize an action of thromboxane A 2 and are expected to have preventive and...
5008277 N-[(alpha-perhaloalkylbenzyloxy)pyridyl]N'-benzoylurea insecticides  
N-[(Alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoylurea compounds of the following structural formula are useful insecticides: ##STR1## in which R A is selected from the group consisting of...
5006549 Novel 7-aroyl-4-hydroxy-3-methyl-benzofurans as dual inhibitors of cyclooxygenase and 5-lipoxygenase  
Novel 7-Aroyl-4-Hydroxy-3-Methyl-Benzofurans of the following general formula (I) are disclosed: ##STR1## The compounds are found to be potent dual inhibitors of cyclooxygenase and 5-lipoxygenase.
5001137 Pyridine compounds and pharmaceutical use thereof  
A novel pyridine compound of the formula ##STR1## wherein each symbol is as defined in the specification, or a salt thereof which exhibit inhibitory activity or prolylendopeptidase and a...
4999371 Substituted 3,4-dihydro-2H-benzopyrans, processes for their preparation, their use and pharmaceutical products based on these compounds  
3,4-Dihydro-2H-benzo[b]pyrans of the formula I ##STR1## are described, in which R 1 is H, OH, (C 1 -C 2 )-alkoxy, (C 1 -C 2 )-alkyl or NR 4 R 5 , R 4 and R 5 being identical or different...
4994465 Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds  
Certain trisubstituted urea compounds as potent inhibitors of the enzyme acyl-CoA:cholesterol acyltransferase, their method of manufacture, pharmaceutical compositions containing such compounds as...
4992465 3-amino-dihydro-(1)-benzopyrans  
4987146 N-hetaryl imidazole derivatives  
N-hetaryl imidazole derivatives of general Formula I ##STR1## are disclosed in which Het represents an optionally substituted monocyclic or bicyclic heteroaromate, R 3 represents hydrogen, a...
4983615 Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders  
There are described compounds of the formula ##STR1## where n is 0 or 1; X is O or NR 2 , R 2 being hydrogen, loweralkyl or loweralkylcarbonyl; R is hydrogen, loweralkyl, arylloweralkyl or...
4981681 Lotion mixture and method of treating psoriasis  
A combination of ingredients consisting of a mixture of predetermined proportions of Purified Water, Methylparaben, Potassium Hydroxide, Hydrogenated Coconut Oil, Glycerine, Polysorbate 60,...
4975455 New heteroarotinoid compounds  
Compounds of general formula (I): ##STR1## in which: R denotes a hydrogen atom, a halogen atom or a hydroxy, lower alkyl, lower alkyloxy, carboxyl, (lower alkyloxy)carbonyl, (lower...
4966896 Derivative of N-methylcarbamate and insecticide containing the same  
An insecticide having high insecticidal activities against various harmful insects, which is low in toxicity to warm-blooded animals and fishes to be used safely. The insecticide comprises a...
4966907 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis  
Novel position-4 and/or position-6 substituted 5-hydroxy-2,3-dihydrobenzofuran and analogs of the following general structural formula (I) are disclosed: ##STR1## These compounds are found to be...
4954518 4H-1-benzopyran-4-one derivative or its salt, process for producing the same and pharmaceutical composition comprising the same as active ingredient  
This invention relates to a 4H-1-benzopyran-4-one derivative represented by the formula: ##STR1## or a salt thereof, a process for producing the same and a pharmaceutical composition comprising the...
4933351 Benzofuran 2-carbox amides useful as inhibitors of leukoriene biosynthesis  
Compounds of the Formula I: ##STR1## and pharmaceutically acceptable salts thereof are inhibitors of leukotriene biosynthesis. These compounds inhibit the mammalian 5-lipoxygenase enzyme, thus...
4927838 Pyridine compounds which are useful in treating a disease state characterized by an excess of platelet activating factors  
The invention relates to compounds of the formula ##STR1## wherein Y and Y' are hydrogen or taken together are O or S, *A is paraphenylene or *----(CH 2 ) n --(X) s --(CH 2 ) r ----, X is O, S...
4921875 Use of amino-substituted benzoic acids as remedies for diarrhea, and medicaments based on these compounds  
A description is given of the use of amino-substituted benzoic acid derivatives of the formula I ##STR1## in which R 1 and R 2 denote hydrogen, (cyclo)alkyl, unsubstituted or substituted phenyl...
4904675 Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines  
Compounds of the formula I ##STR1## wherein the groups A, R 1 , R 2 and R 3 are as defined in the specification, exhibit valuable pharmacological properties, especially as antifibrotic agents....
4904674 1-(Benzo[b]thienyl)-2-(thienyl)ethenes and related compounds useful as anti-inflammatory agents  
Novel 1-(benzo[b]thienyl)-2-(thienyl)ethenes, processes for the preparation thereof, and methods of reducing inflammation utilizing compounds and compositions there are disclosed.
4897415 2-imino-1,3-dithietanes, their use as pesticides  
There are described new 2-imino-1,3-dithietanes of general formula I ##STR1## in which R is the group ##STR2## in which A is CFHal, C(CH 3 )C 1 -4 -alkyl, C(CH 3 )CHal 3 , C(CH 3 )CF 2 Cl, C(CH 3...
Matches 301 - 350 out of 469 < 1 2 3 4 5 6 7 8 9 10 >