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9023870 Positive allosteric modulators of nicotinic acetylcholine receptor  
The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The...
9012360 Synergistic combinations of active ingredients  
The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and A have the meanings given in the description...
9006269 Azetidine derivatives  
Compounds of formula (I) are inhibitors of fatty acid amide hydrolase, (FAAH), and which are useful in the treatment of diseases or medical conditions which benefit from inhibition of FAAH...
8969352 Substituted 2-azabicycles and their use as orexin receptor modulators  
The present invention is directed to compounds of Formula I: wherein X is N or CR1; Y is N or CR2; R1 is H, alkoxy, halo, triazolyl, pyrimidinyl, oxazolyl, isoxazole, oxadiazolyl, or pyrazolyl; R2...
8962003 Insect behaviour modifying compounds  
The invention provides methods for controlling thrips populations using thrips-repelling and/or thrips-attracting agents. The invention also provides methods of preventing or minimizing damage to...
8937055 Heterocyclic ring compound having muscle cell or adipocyte differentiation regulating action  
The present invention provides a compound having a muscle cell or adipocyte differentiation regulating action, useful for the prophylaxis or treatment of diseases such as diabetes, obesity,...
8916553 Sulfonamide compounds useful as CYP17 inhibitors  
Disclosed are sulfonamide compounds of Formula (I): or stereoisomers, N-oxides, prodrugs, or pharmaceutically acceptable salts thereof, wherein ring A, R1, R2, R3, R4 and R5 are defined herein....
8906939 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives  
The present invention relates to novel compounds, in particular novel pyridinone derivatives according to Formula (I) including any stereochemically isomeric form thereof, or a pharmaceutically...
8895587 Insecticidal compounds based on arylthioacetamide derivatives  
The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, G1, n, A1, A2, A3, A4, Y1, Y2, and Y3 are as defined in the claims. The invention also relates to processes and...
8895586 Methods of treating emesis  
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor. The compounds have the...
8895585 Nicotinamide derivative or salt thereof  
An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide...
8889672 Compounds, formulations, and methods of protein kinase C inhibition  
The invention provides a method of inhibiting atypical protein kinase C (aPKC) comprising contacting an aPKC with a compound having a structure selected from the group consisting of structural...
8889694 N-alkoxyamides of 6-(substituted phenyl)-4-aminopicolinates and 2-(substituted phenyl)-6-amino-4-pyrimidinecarboxylates and their use as selective herbicides for crops  
N-Alkoxyamides of 4-aminopicolinic acids and 6-amino-4-pyrimidinecarboxylates are selective herbicides for corn, canola and sugar beet.
8883180 Active compound combinations  
The invention relates to active compound combinations, in particular a fungicidal and/or insecticidal composition, comprising Isotianil (3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide)...
8883850 Naphthalene carboxamide M1 receptor positive allosteric modulators  
The present invention is directed to naphthalene carboxamide compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which...
8883811 Synergistic fungicidal mixtures for fungal control in cereals  
A fungicidal composition containing a fungicidally effective amount of a compound of Formula I-V and at least one fungicide selected from the group consisting of epoxiconazole, prothioconazole,...
8883824 3-(4-aminophenyl)-2-furancarboxylic acid derivative and pharmaceutically acceptable salt thereof  
Disclosed is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 is 1: a C3-8 cycloalkyl C1-4 alkyl group,2: a C7-14 aralkyl group, in which the aryl...
8877783 Isoxazolo-pyridine derivatives  
The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and...
8877782 Isoxazolo-pyridine derivatives  
The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and...
8865746 Methods of treating an overweight or obese subject  
The invention herein generally relates to pharmaceutical formulations and methods of treating an overweight or obese subject, and overweight- or obesity-related conditions.
8859591 Glucagon receptor modulators  
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds...
8853125 Pyrazole compounds for controlling invertebrate pests  
The present invention relates to a method for controlling invertebrate pests which method comprises treating the pests, their food supply, their habitat or their breeding ground or a plant, seed,...
8853244 Thiophene-carboxamides useful as inhibitors of protein kinases  
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of...
8846717 Stable insecticide compositions and methods for producing same  
Insect controlling compositions including an N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximine compound exhibiting increased stability, along with methods for preparing same, are disclosed.
8846568 Active compound combinations having insecticidal and acaricidal properties  
The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in whichR1 and A have the meanings given in the...
8846719 Isoxazolo-pyridine derivatives  
The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and...
8846567 Active compound combinations having insecticidal and acaricidal properties  
The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in whichR1 and A have the meanings given in the...
8841328 Selective insecticides based on anthranilic acid diamides and safeners  
The present invention relates to the use of selective insecticidal compositions, characterized by an effective amount of an active compound combination comprising (a) (1) at least one...
8841321 Quinoline derivatives as antibacterial agents  
Use of a compound for the manufacture of a medicament for the treatment of a bacterial infection provided that the bacterial infection is other than a Mycobacterial infection, said compound being...
8835461 Substituted 3-hydroxy-4-pyridone derivative  
This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having...
8835463 Compounds having analgesic and/or immunostimulant activity  
The compounds shown by their structural formulas in the specification have analgesic and or immunostimulant activity in mammals.
8835462 Macrocyclic picolinamides as fungicides  
The disclosure relates to macrocyclic picolinamides of Formula I and their use as fungicides.
8828907 Active ingredient combinations having insecticidal and acaricidal properties  
The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and A have the meanings given in the description...
8828906 Active compound combinations having insecticidal and acaricidal properties  
The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and A have the meanings given in the description...
8815915 Benzofuran-2-sulfonamides pyridine derivatives as chemokine receptor modulators  
The present invention relates to novel benzofuran-2-sulfonamide pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as...
8815914 Positive allosteric modulators of nicotinic acetylcholine receptor  
The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The...
8809373 Pyridine non-classical cannabinoid compounds and related methods of use  
Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.
8809371 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Nicotinamide derivative or salt thereof
 
An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide...
8796311 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
 
The present invention relates to novel compounds, in particular novel pyridinone derivatives according to Formula (I) including any stereochemically isomeric form thereof, or a pharmaceutically...
8796175 Method for enhancing plant intrinsic defense  
The invention relates to the use of at least one compound selected from the class of the sulphoximines for enhancing plants' intrinsic defenses and/or for improving plant growth and/or for...
8785480 Functionalized pyridine N-oxides and processes for the preparation of the same  
In one embodiment, processes for the preparation of certain functionalized pyridine N-oxides are provided. In one form, the functionalized pyridine N-oxides include...
8785468 Phenylalanine amide derivatives useful for treating insulin-related diseases and conditions  
Provided herein are compounds of formula I: wherein A, B, X, R1, R2 and subscript n are as defined in the following disclosure. Compositions comprising the compounds are also provided, as well as...
8778977 Pyridinonyl PDK1 inhibitors  
The present invention provides pyridinonyl PDK1 inhibitors and methods of treating cancer using the same.
8771665 Inhibitors of hepatitis C virus polymerase  
The present invention provides, among other things, compounds represented by the general Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y, R1A, R1B, R2, and R3 are as defined...
8772320 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Nicotinamide derivative or salt thereof
 
An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide...
8765732 Aryl- or heteroaryl-substituted benzene compounds  
The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of...
8765790 Positive allosteric modulators of nicotinic acetylcholine receptor  
The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The...
8748461 Metalloenzyme inhibitor compounds  
The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
8722707 Compositions and methods for inhibition of smooth muscle cell proliferation and neointimal hyperplasia  
Compositions and methods for treating post angioplasty restenosis, arteriosclerosis, and/or smooth muscle cell proliferation and/or neointimal hyperplasia in vascular tissues, and at least one...
8716316 Positive allosteric modulators (PAM)  
The present invention relates to phenylethynyl compounds of formula I wherein R1, R2, X, L, R3, R4, R4′, cyc, and n are as defined in the specification and claims and to a pharmaceutically...