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7622450 |
Flavone C-glycoside derivatives and compositions containing the derivatives
The present invention relates to novel flavone C-glycoside derivatives or salts thereof, especially those showing an anti-allergic effect, and compositions containing them. Recently, cases of...
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7618946 |
Analgesic compounds, extracts containing same and methods of preparation
Various compounds obtained from plants of the Barringtonia species which are derived from Barringtoside A and Barringtoside C as precursor compounds which especially have an arabinopyranosyl...
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7605135 |
Baicalin as a treatment for SARS infection
The present invention relates to a pharmaceutical composition useful for the treatment of diseases associated with viruses of the order Nidovirales of the family Coronaviradae, such as Severe Acute...
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7557091 |
HKI10311129, novel antibiotic, method for producing the same and the use thereof
The invention relates to the novel antibiotic HKI10311129 which has a molecular weight of 1113 and the summation formula C 56 H 75 NO 22 . The invention also relates to a method for producing said...
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7544668 |
Saponins derived from Ilex pubescens and method of purifying the same
Two hitherto unreported novel triterpene saponins were isolated in substantially pure form from the root of Ilex pubescens . The chemical structures and some properties of the triterpene saponin...
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7541342 |
Use of PKC-activating compounds as cardioprotectants and as apoptosis-inducing anti-tumor agents
Compounds for the inducing apoptosis in cancer cells are described. The described compounds induce the translocation of protein kinase C-δ to the mitochondria and the phosphorylation of...
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7534768 |
Treatment of DNA viral infections
The synergistic combination of a loop diuretic and a cardiac glycoside is useful in the treatment of DNA viral infections.
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7531521 |
Formulation for use in the prevention and treatment of carbohydrate induced diseases and conditions
The present invention provides a novel method for inhibiting sugar-induced weight gain resulting from fructose and glucose driven lipogenesis. The method for inhibiting sugar-induced weight gain is...
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7524824 |
Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
This invention provides compositions, methods and process of producing extracts from Xanthoceras sorbifolia . The extract comprises alkaloids, coumarins, saccharides, proteins, polysaccharides,...
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7514412 |
Anticancer biangeloyl saponins
Novel compounds such as compounds designated herein as Y or Y3, Y1, Y2, Y8, Y9 and Y10 are disclosed. These compounds have anticancer activity. The compounds of the present invention are obtainable...
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7435756 |
Preparation and diabetic use of gibberellins
The present invention relates to application of compounds of formula (1) (Gibberellins) and their derivatives for the preparation of a pharmaceutical composition or medicaments for the treatment of...
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7387790 |
Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7288534 |
Sphingomyelin enhancement of tumor therapy
Cytotoxic tumor therapy in a patient is enhanced by co-administration of sphingomyelin. The invention most likely enhances a tumor cell's ability to undergo ceramide-induced apoptosis by increasing...
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7232805 |
Cobalamin conjugates for anti-tumor therapy
The present invention provides a cobalamin-drug conjugate suitable for the treatment of tumor related diseases. Cobalamin is indirectly covalently bound to an anti-tumor drug via a cleavable linker...
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7204996 |
Method of cancer treatment
This invention comprises a method of treating a subject having relapsed or refractory cancer such as leukemia with liposomal annamycin including the steps of
(a) evaluating the subject to...
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7202222 |
Methods for treatment of obesity and effective fat loss promotion
Methods for treating obesity, reducing total weight and reducing body fat mass by administering a composition comprising dihydroquercetins and root-derived aralosides A, B, C and D is disclosed.
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7163702 |
Process for isolating sea cucumber saponin Frondoside A, and immunomodulatory methods of use
This present invention discloses use of a chloroform/solvent mixture extraction at different solvent-to-feed ratios, followed by evaporation and extraction with ethyl acetate/water; followed by...
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7157078 |
Devices and methods for eliminating termite colonies
This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing
a) a termiticide selected...
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7153877 |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and...
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7144867 |
Anticancer glycoside compounds
The present invention relates to new classes of anti-cancer compounds. In particular, the present invention provides glycoside compounds as anti-cancer agent, alone, or in combination with other...
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7132403 |
Antihelminthic anthraquinones and method of use thereof
Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the...
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7119110 |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and...
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7105492 |
Camptothecin derivatives having antitumor activity
Camptothecin derivatives of camptothecin of formula (I)
exhibit antitumor activity and show a good therapeutic index and are used in the treatment of tumors, viral infections and antiplasmodium...
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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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7091189 |
Medicament for treating lung cancer
By using a combination of amrubicin or a pharmaceutically acceptable salt thereof with another medicament for treating lung cancer (irinotecan, vinorelbine, gemcitabine, etc.), it is intended to...
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7071233 |
Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases
An improved medical treatment and medicine is provided to quickly and safely resolve HIV and other microbial infections. The inexpensive medicine can be self administered and maintained for the...
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7060686 |
Anti-inflammatory compounds derived from Pseudopterogorgia elisabethae
Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural...
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7049301 |
Quercetin derivatives and their medical usages
This invention relates to quercetin derivative, its preparation, and a pharmaceutical combination, as well as their medical uses for the prevention or treatment of diseases related to 5HT 1A ...
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7008929 |
Sapogenin-based treatment
The present invention relates to the use of a sapogenin, chosen from diosgenin and hecogenin, and/or of a plant extract containing at least one of these sapogenins. A preferred use is the treatment...
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6946490 |
Antimicrobial treatment for herpes simplex virus and other infectious diseases
An improved medical treatment and medicine is provided to quickly and safely resolve herpes and other microbial infections. The inexpensive user-friendly medicine can be applied and maintained on...
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6903076 |
Antihelminthic anthraquinones and method of use thereof
Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the...
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6900239 |
Tumor chemopotentiation using isocoumarin derivatives
A method for enhancing the efficacy of chemotherapy in the treatment of cancer in animals, particularly humans, is provided wherein isocoumarin derivatives that exhibit unique chemopotentiation...
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6875746 |
Anticancer anthraquinones and method of use thereof
Anthraquinones are described which have anticancer or antitumor activity and which are useful for inhibiting cancer cells and cells comprising tumors in vitro or in vivo. Preferably, the...
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6875745 |
Method and composition for the treatment of cancer
We have discovered that the administration of a G1 and/or S phase drug such as β-lapachone in combination with a G2/M drug such as a taxane derivative such as paclitaxel resulted in a greater than...
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6872709 |
Therapeutic agent for mastitis of livestock and method for treating mastitis using the same agent
The present invention provides a therapeutic agent and therapeutic method for treatment of mastitis in livestock comprising glycyrrhizin and pharmaceutically acceptable salts thereof as effective...
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6852694 |
Stabilized insulin formulations
The present invention is directed to stabilized insulin composition comprising a mixture of insulin species such as insulin and an insulin analog. As disclosed herein, insulin compositions...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6784159 |
Triterpene saponins from soybeans for treating kidney disease
A method of treating polycystic kidney disease is described. The method involves administering soyasaponin B b to an animal in need thereof.
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6713074 |
Cosmetic composition and method
The cosmetic topical formulation of this invention is directed toward diminishing skin wrinkling, fine line, improving skin tone, and combinations thereof. Preferably, the topical formulation...
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6699841 |
Method of preparing physiologically acceptable aqueous solutions, and solutions thus obtained
A physiologically acceptable aqueous solution, and water-soluble compositions suitable for obtaining it, comprising a first physiologically acceptable compound of an acidic nature and a second...
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6693085 |
Macrolide compound JK
Compound JK represented by the general formula (1): wherein R is H or —CH 3 ; or a pharmaceutically acceptable salt thereof. Compound JK has an excellent antimicrobial activity even against...
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6635677 |
Methoxyamine combinations in the treatment of cancer
This invention generally relates to novel compositions and methods for the treatment of certain cancers. Additionally, this invention relates to novel compositions and methods to screen drugs for...
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6605447 |
Methods and means of detecting nitric oxide synthase
Methods for identifying and monitoring increased or decreased levels of inducible nitric oxide synthase in biological samples are provided. A collection device for detecting inducible nitric oxide...
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6593303 |
Anti-tumor synergetic composition
There are provided the combined use of 4-demethoxy-3′-deamino-3′-aziridinyl-4′-methansulfonyl
daunorubicin or 4-demethoxy-N,N-bis(2-chloroethyl)-4′-methansulfonyl daunorubicin and an...
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6589939 |
Camptothecin derivatives having antitumor activity
Camptothecin derivatives of camptothecin of formula (I): wherein the groups R 1 , R 2 and R 3 are as defined in the description are disclosed. The compounds of formula (I) are endowed with...
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6559184 |
Methods and compositions for treating male erectile dysfunction
Administration of a pharmaceutical composition in the form of a suppository comprising: (a) a prostaglandin vasodilator; (b) 15-hydroxyprostaglandindehydrogenase inhibitor: and (c) a base material...
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6541462 |
Sphingomyelin enhancement of tumor therapy
Cytotoxic tumor therapy in a patient is enhanced by co-administration of sphingomyelin. The invention most likely enhances a tumor cell's ability to undergo ceramide-induced apoptosis by increasing...
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6538027 |
Compositions comprising ratite oil or active fractions thereof and methods of using these composition as insect repellents
This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained...
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6528058 |
Saponin adjuvant composition
Art adjuvant composition for stimulating an effective immune resposne to an antigenic substance when co-administered to an animal with said antigenic substance, comprising: (a) a saponin with...
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