Matches 251 - 300 out of 670 < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 >
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6133261 Amino acid derivatives useful to treat stroke  
The invention provides a therapeutic method for treating or preventing stroke and other ischemic disorders, as well as novel compounds and pharmaceutical compositions useful for carrying out such...
6127385 Method of treating depression using l-threo-methylphenidate  
A method of treating depression to elicit prompt relief from depression is disclosed. The method comprises the step of administering orally or non-orally to said patient, a therapeutically...
6124346 Estrogen agonist/antagonists treatment of atherosclerosis  
A method of treating atherosclerosis, independent of lipid lowering, in mammals, including humans, in need of treatment by inhibiting progression of an atherogenic lesion or by stabilizing plaque....
6121289 Method for enhanced brain delivery of nicotinic antagonist  
This invention provides methods of treatment of addiction to tobacco comprising intranasal administration of nicotinic antagonists.
6121272 Bidentate metalloprotease inhibitors  
The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular,...
6110935 Benzofurazan compounds for enhancing glutamatergic synaptic responses  
Compounds of the general structural formula ##STR1## are shown to have AMPA receptor enhancing properties. The compounds are useful for such therapeutic purposes as facilitating the learning of...
6103131 Methods for controlling biofouling using sulfamic acids  
The invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one sulfamic acid or...
6096759 Method for treating essential hypertension  
This invention relates to the treatment of essential hypertension by administration of anti-hypertensive effective amounts of 4-hydroxy-2,2,6,6-tetramethyl-1-piperidine-1-oxyl (tempol).
6096761 Esters of 3-hydroxy-piperidinemethanol derivatives  
The present invention of compounds of formula (I), ##STR1## a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereof, R 1 is C...
6090823 Remedy for spinal injury  
(+)-N,N'-Propylene dinicotinamide or pharmaceutically acceptable salts thereof are outstanding drugs of high safety that can heal or ameliorate spinal cord injuries, prevent the transition from an...
6087348 Use of NK-1 receptor antagonists for treating stress disorders  
The present invention provides the use of an orally active, long acting, CNS-penetrant NK-1 receptor antagonist for the manufacture of a medicament adapted for oral administration for the treatment...
6077839 Method for reducing intraocular pressure in the mammalian eye by administration of gamma aminobutyric acid (GABA) agonists  
Ophthalmic compositions and a method are disclosed for treating glaucoma and/or ocular hypertension in the mammalian eye by topically administering to the mammalian eye the ophthalmic composition...
6075022 Methods and compositions for controlling biofouling using thiourea compounds  
The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one thiourea...
6066650 Inhibitors of microsomal triglyceride transfer protein and method  
Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the...
6048854 2,3-diaminopropionic acid derivative  
The present invention relates to a 2,3-diaminopropionic acid derivative of the formula (1): ##STR1## or a pharmaceutically acceptable salt thereof. The compounds of the present invention are useful...
6043251 Use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyr idine for preparing drugs for treating amyotrophic lateral sclerosis  
6037351 Method of inhibiting hepatitis B virus  
6037347 Combination preparation for use in dementia  
The invention relates to a composition which is a pharmaceutical combination preparation comprising a compound which has an acetylcholinesterase-inhibitory action or exhibits muscarinergic action...
6037334 Phosphonates, process for preparing the same and medicaments  
6034081 Potentiation of biocide activity using an N-alkyl heterocyclic compound  
A method for increasing the effectiveness of a microbicide is described, wherein a microbicide and an N-alkyl heterocyclic compound are applied to a substrate or aqueous system subject to the...
6034067 Serine protease inhibitors  
The invention relates to a compound having formula (I), wherein A, B, X, N, Z and Q are defined as described in the description. The compounds of the invention have anticoagulant activity and can...
6030971 Methods and compositions for controlling biofouling using amides  
The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one amide to...
6030952 Benzofuran-acrylic acid derivatives and their use as modulators of RXRs or RARs receptors  
6028082 Human NK.sub.3 receptor-selective antagonist compounds, method for obtaining them and pharmaceutical compositions containing them  
Compounds of formula (I), a method for obtaining them and pharmaceutical compositions containing them are described. The compounds are useful as human NK 3 receptor antagonists.
6020344 Enzyme inhibitors and methods of use  
Novel enzyme-inhibitory compounds are disclosed. The subject invention further pertains to methods and compositions for the inhibition of bacteria, viruses, parasites, and other pathogens.
6017929 Cholinesterase activator  
6015837 Method for treating scoliosis with β2-adrenoceptor agonists  
A method of treating scoliosis by adminstering β 2 adrenergic agonists in amounts sufficient to correct the condition.
6008244 Halopropargyl compounds as marine antifouling agents  
Disclosed is a method of inhibiting the growth of marine organisms on a marine structure, by applying onto or into the marine structure a halopropargyl quaternary ammonium compound, halopropargyl...
6004933 Cysteine protease inhibitors  
The present invention relates to cysteine protease inhibitors of the general formula (I): ##STR1## wherein Z is a cysteine protease binding moiety; X and Y are S, O or optionally substituted N; and...
6004977 N-(pyridinylamino) isoindolines and related compounds  
Novel N-(pyridinylamino)isoindolines and related compounds, intermediates and processes for the preparation thereof, and methods of relieving memory dysfunction and treating depression utilizing...
6001853 Hydroxylamine compositions for the prevention or retardation of cataracts  
A pharmaceutical composition and treatment to inhibit the development of cataracts in the crystalline lens of the eye by administering a hydroxylamine to a subject at risk of developing a cataract....
5985926 Method for inhibiting intracellular viral replication  
There is disclosed a method of preventing or delaying the occurrence of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV) seropositive humans by administering an...
5977180 Anandamide analog compositions and method of treating intraocular hypertension using same  
Anandamide analogues useful for the treatment of intraocular hypertension, as well as ophthalmic compositions comprising the same and a cyclodextrin, and methods of use of these compounds to treat...
5972962 Treatment of pruritus  
The use of certain known 1,3,4 trisubstituted 4-aryl-piperidines for the treatment of pruritus in humans and animals is disclosed.
5972952 Neuroprotective pharmaceutical composition containing stereoisomers of arylcyclohexylamines  
The invention relates to pharmaceutical compositions for neuroprotection containing the compound (1S,2R) 1-[1-(2-thienyl)-2-alkylcyclohexyl]piperidine or (1S,2R)...
5972940 Arginine analogues having nitric oxide synthase inhibitor activity  
A compound selected from the group consisting of a compound of the formula wherein A is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and --NO 2 , E is --O-- or a...
5972892 Topical composition containing a substance P antagonist  
The invention relates to a therapeutic composition for topical application containing at least one product with an irritant side effect and a substance P antagonist for reducing or even eliminating...
5958881 Composition containing VIP for injection and a method of enhancing visualization of tissues during medical procedures  
A method of inducing a temporary substantial paralysis of an area of interest in a patient undergoing a medical procedure is provided. The method involves administering a therapeutically effective...
5948912 Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands  
Disclosed are compounds encompassed by general formula (I), wherein, A represents ethenylene, or A represents --X--CH 2 --; where X is carbon or oxygen, provided that when X is oxygen, the oxygen...
5945420 Immunopotentiating and infection protective agent and production thereof  
An immunopotentiating and infection protective agent comprising riboflavin and/or a riboflavin derivative, which is safe for the human, animals or the like, an immunopotentiating and infection...
5935953 Methods for controlling invertebrate pests using cocaine receptor binding ligands  
The invention relates to a method of controlling an invertebrate pest, comprising contacting the pest with a pest-controlling amount of an agent having substantial inhibitory activity toward a...
5929088 Cyclic amino acids as pharmaceutical agents  
Novel cyclic amino acids of formula (Ia) or (Ib) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders,...
5925634 Use of ibogaine for treating neuropathic pain  
This invention discloses that ibogaine, a plant derivative, can be used safely to treat neuropathic pain (i.e, pain which does not respond conventionally to opiate drugs such as morphine). Ibogaine...
5925616 Treatment of fungal infections using a combination of an anti-fungal compound and an H-alkyl heterocyclic compound  
A method for increasing the effectiveness of an anti-fungal compound is described. In the method, an anti-fungal compound and an N-alkyl heterocyclic compound or a salt thereof are administered to...
5925646 Heterocyclic aryl-, alkyl- and cycloalkylacetamides  
The heterocyclic aryl-, alkyl- and cycloalkylacetamides are prepared by reacting the appropriately substituted acetic acids with amines, if appropriate in complexed form. The heterocyclic aryl-,...
5919829 Gastrin and cck receptor ligands  
Compounds of formula (Ia), (Ib), or (Ic), wherein A represents a group having two fused rings, or a group of formula (Id), R 1 (m) represents up to 6 substituents, K represents --O--, --S--, --CH 2...
5919781 Use of NK-1 receptor antogonists for treating substance use disorders  
The present invention provides a method for the treatment or prevention of substance use disorders using an orally active, long acting, CNS-penetrant NK-1 receptor antagonist and pharmaceutical...
5914324 6-Hydroxy and 6-oxo-androstane derivatives active on the cardiovascular system and pharmaceutical compositions containing same  
6-hydroxy and 6-oxo-androstane derivatives of formula (I), active on the cardiovascular system. ##STR1## wherein: the symbol A represents CH--OR, CN--OR, CH--CHN--OR and CCH--N--OR; and R...
5912255 Topical fluoroquinolone antibiotics combined with benzoyl peroxide  
A pharmaceutical composition of all fluoroquinolones, including but not limited to, ciprofloxacin, ofloxacin, enoxacin, cinoxacin, pefloxacin, lomefloxacin, norfloxacin, tosufloxacin, fleroxacin,...
5908863 Geminal carboxylic acids and esters thereof pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism  
Compounds of formula I: ##STR1## wherein R a , R b , Φ, B and R are as defined in the disclosure, have antagonistic activity on osteoclast hyper-reactivity.
Matches 251 - 300 out of 670 < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 >