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5064815 |
Primycin-containing colloidal basic gel
This invention relates to a primycin-containing colloidal basic gel comprising 5-30% of primycin and 95-70% of N-methyl-pyrrolidone-2. The invention also relates to antibacterial compositions...
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5059591 |
Drug preparations of reduced toxicity
Preparations of drugs in admixture with certain ligands are described which, when administered to animals or humans, are less toxic than conventional drug preparations. Although the toxicity of the...
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5032582 |
Method for treating fungal infections with amphotericin B/cholesterol sulfate composition
An amphotericin B composition containing particles of amphotericin B and cholesterol sulfate, in a molar ratio of between about 1:1 to 1:4. The particles, when stored in lyophilized form and...
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5023242 |
Primycin salts
The invention relates to salts of primycin formed with an organic acid--preferably a C 1 -16 aliphatic carboxylic acid, a halogenated carboxylic acid, an aliphatic dicarboxylic acid, an aromatic...
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4978654 |
Composition and method for treatment of disseminated fungal infections in mammals
A method is disclosed for treatment of disseminated fungal infection in a mammal comprising the administration of a fungicidally effective amount of Amphotericin B encapsulated in a substantially...
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4973465 |
Microcrystals comprising an active substance having an affinity for phospholipids, and at least one phospholipid, process of preparation
The present invention relates to microcrystals of a substance, which substance is insoluble in water and has an affinity for phospholipids, as well as a process for its preparation. According to...
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4950432 |
Polyene microlide pre-liposomal powders
The present invention involves a process for producing fine powder suitable for the preparation of antifungal polyene microlide-containing liposomes upon suspension in an aqueous solution. This...
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4902789 |
Process and composition for the purification of amphotericin B
A unique four-solvent system comprising methanol, dimethylformamide, methylene chloride and water is employed to provide an improved process for the purification and crystallization of amphotericin B.
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4883785 |
Complex of anti-fungal agent and cyclodextrin and method
An anti-fungal complex formed of a polyene anti-fungal agent, such as amphotericin B, and cyclodextrin, preferably γ-cyclodextrin, is provided. The complex which includes amphoterin B has improved...
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4879274 |
External medication for skin
Novel external medications comprise, as essential components, the following three components (A) to (C): (A) an α-monoglyceryl ether represented by the following formula (I): ##STR1## wherein R...
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4867970 |
Moistureless oral drug delivery formulation and method for preparing same
Oral drug delivery systems are provided formed of compositions which include one or more hydrocolloids solids, such as gelatin, pectin, and sodium carboxymethyl cellulose, and preferably mixtures...
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4831018 |
Polyene antibiotic emulsion formulation
A polyene antibiotic emulsion formulation comprising a therapeutically effective amount of the antibiotic incorporated into an oil-in-water emulsion, and a method of treating an active infection in...
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4826822 |
Liquid suspensions of polyene antibiotics and use thereof for slime control in industrial waters
A process and composition for controlling slime in industrial waters by the control of slime-forming fungi in the waters. The process comprises the step of adding an effective amount of a polyene...
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4822777 |
Amphotericin B/cholesterol sulfate composition
An amphotericin B composition containing particles of amphotericin B and cholesterol sulfate, in a molar ratio of between about 1:1 to 1:4. The particles, when stored in lyophilized form and...
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4812312 |
Liposome-incorporated nystatin
The present invention involves a liposomal agent for treating disseminated fungal infection in an animal. This liposomal agent comprises the polyene antifungal compound nystatin. The nystatin is...
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4766046 |
Stabilized liposome/amphotericin composition and method
A dehydrated liposome/amphotericin B composition which, upon addition of an aqueous medium, forms a suspension of liposomes (a) having a predetermined size distribution in size range less than...
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4748117 |
Method for forming amphotericin B crystals in fermentation broth
A new method is provided for forming crystals of amphotericin B directly in fermentation broth which crystals are easily separable without use of costly solvent extraction techniques which method...
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4744989 |
Method of preparing liposomes and products produced thereby
A method is provided for preparing stable liposome precursors in the form of a water-soluble carrier material coated with a predetermined amount of a thin film of liposome components, which method...
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4680315 |
Powder mixture having high propylene glycol content and process for the preparation thereof
The invention refers to a powder mixture having a high propylene glycol content and a process for the preparation thereof. The powder mixture consists of 25 to 75 percent by weight of propylene...
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4600706 |
Anti-fungal feed compositions containing natamycin
An animal feed composition which comprises a conventional animal feed and an antifungal-effective amount of natamycin. The feed composition may comprise natamycin in a range of about 0.000055 to...
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4560553 |
Use of eucalyptol for enhancing skin permeation of bio-affecting agents
Eucalyptol is used to enhance skin permeation of bio-affecting agents.
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4542020 |
Long-lasting adhesive antifungal suppositories
Antifungal suppositories are provided which preferably include nystatin as the antifungal agent, together with a hydrocolloid, such as sodium carboxymethylcellulose or hydroxypropylmethylcellulose...
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4536494 |
Animal feed method employing natamycin
An animal feed composition which comprises a conventional animal feed and a feed efficiency-effective amount of natamycin. The feed composition may comprise natamycin in a range of about 0.000055...
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4478822 |
Drug delivery system utilizing thermosetting gels
This invention relates to a unique drug delivery system for delivering drugs to a body cavity. The drug delivery system comprises a medicament and a polymer such that the drug delivery system is a...
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4474748 |
Medicaments potentiated with phenyl alkanols
Antimicrobial compositions are provided wherein there is obtained an enhancement of activity by combining the antimicrobial agent with an effective amount of a potentiator. The potentiator is...
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4474751 |
Ophthalmic drug delivery system utilizing thermosetting gels
This invention describes the application of selected polymers as novel drug delivery systems which use the body temperature and pH to induce a liquid to gel transition of the polymer which contains...
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4442091 |
Process for combatting and/or preventing allergic diseases employing natamycin
The invention provides a method for combatting and/or preventing allergic diseases which are caused by house-dust mites by treating said mites or places or areas which are afflicted or may be...
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4396610 |
Water-soluble guanidine derivatives of polyene macrolides and the esters thereof, and process for preparation thereof
New guanidine derivatives of polyene macrolides having at least one free amino group and at least one free carboxy group (e.g. nystatin, pimaricin, amphotericin B, candicidin and trichomycin) are...
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4342750 |
Method for treating benign prostatic hypertrophy with N-acyl amphotericin B
Orally administered compositions for treating benign prostatic hypertrophy are described herein. These compositions contain an effective dose of N-acyl amphotericin B. Also, the method of treating...
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4327087 |
Stabilized Netilmicin formulations
A highly pH- and color-stabilized parenteral formulation is provided comprising an aqueous solution of a salt of an aminoglycoside containing an allylic amine and having a pH between 5.0-7.0.
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4321257 |
Potentiated medicaments
Antimicrobial compositions are provided wherein there is obtained an enhancement of the activity of an antimicrobial agent exemplified by quarternary ammonium compounds, bisdiguanides, anti-fungal...
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4177265 |
Process for the purification of amphotericin B and A solubilizing media useful in that process
Acetone or methanol saturated with sodium iodide or sodium thiocyanate are useful solubilizing media for amphotericin B.
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4148891 |
Antifungal preparations
An antifungal preparation to be used in and on agricultural products such as fruit, vegetables, tubers, root-tubers, flower bulbs and rootstocks comprising an amount of polyene antibiotic,...
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4144328 |
N,N,N-Trimethyl derivatives of polyene amphoteric antibiotics, process of producing same and pharmaceutical composition
The present invention relates to novel substances; namely, to N,N,N-trimethyl derivatives of polyene amphoteric antibiotics, and to a process of producing same, said substances having the following...
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4144327 |
Antimicrobial composition comprising lytic enzymes from physarum and an antimycotic agent
The present invention encompasses an antimicrobial composition comprising an extract of lytic enzymes from Physarum. These lytic enzymes are particularly effective antimycotic agents when used in...
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4102998 |
Process for the prevention of venereal disease
An intrauterine contraceptive device comprising an elongated shank having divergent convoluted portions at its distal end, said convoluted portions being generally sinusoidal in nature, said device...
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4048309 |
Topical steroid ointment formulations
Steroid ointment formulations of the solution and biphasic types which are used as topical anti-inflammatory agents are provided wherein the steroid, such as 21-chloro-9α-fluoro-Δ 4 ...
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4025620 |
Treatment of canine otitis and composition therefor
A liquid veterinary composition for treating canine otitis externa containing diethanolamine fusidate and an anti-fungal antibiotic such as nystatin. The composition additionally contains a broad...
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4002741 |
Meglumine complex fungicidal polyene macrolide antibiotic compositions and treatment method
Medicated compositions which contain as active ingredients meglumine complexes of fungicidal polyene macrolide antibiotics and treatment method utilizing these compositions is described. These...
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3378441 |
Tetraene antibiotic purification
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3323991 |
Synergistic coccidiostatic compositions and methods
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3244590 |
Polyenic compounds and procedures related thereto
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3232766 |
Preservation of beer
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3094460 |
Decoyinine
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3025217 |
Dry amylopectin therapeutic dusting powders
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3629414 |
Title is not available
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3740424 |
Title is not available
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3777018 |
Title is not available
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3651218 |
Title is not available
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