Matches 51 - 100 out of 149 < 1 2 3 >
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6228843 Method of using PKC inhibiting compounds to treat vascular disease  
A method for treating pulmonary and systemic vascular diseases associated with cardiac hypotrophy, dysfunction or failure that involves the administration of an effective amount of a PKC antagonist...
6171856 Methods and compositions relating to no-mediated cytotoxicity  
The present invention relates to methods and compositions for the treatment of diabetes involving free radicals. In particular, the present invention is directed to the treatment or prophylactic...
6146675 Foodstuff preservation  
A natural microbiocidal and/or microbiostatic composition wherein the sole antibiotic antimicrobiocidal agent is Natamycin which inhibits or destroys yeast and mold in selected foodstuffs.
6143726 Complexes of N'-dimethylaminoacetylpartricin A dimethylaminoethylamide, or the salts thereof, and cholesterol 3-sulphate  
A complex containing N'-dimethylaminoacetylpartricin A dimethylaminoethylamide, as a salt or as the free base, and cholesterol 3-sulphate, in a molar ratio between 1:0.5 and 1:10, respectively.
6121244 Antitumoral method by administration of partricin derivatives  
The use of some semisynthetic derivatives of the antifungal polyene partricin to selectively hinder the growth of tumor cells is here described. Their use can be associated with the use of other...
6107283 Cardiac glycosides inhibit proliferation of cells bearing FGF receptors  
This invention provides methods of inhibiting the export of a leaderless protein from a cell by contacting the cell with a cardiac glycoside or aglycone derivative. Leaderless proteins include...
6083706 Inhibitors of leaderless protein export  
Methods of inhibiting the export of a leaderless protein from a cell by contacting the cell with a compound that inhibits the binding of the leaderless protein and a transport molecule are...
6071885 Treatment of FGF-mediated conditions by administration of a cardiac glycoside or aglycone derivative thereof  
This invention provides methods of inhibiting the export of a leaderless protein from a cell by contacting the cell with a cardiac glycoside or aglycone derivative. Leaderless proteins include...
6069126 Antifungal combination therapy  
There is described antifungal combination therapy comprising the use of known antifungal agents such as the azoles or polyenes in combination with a pneumocandin derivative antifungal agent. More...
6045815 Parenteral pimaricin as treatment of systemic infections  
An antifungal composition suitable for parenteral administration to a mammal includes an amount of pimaricin or an antifungal derivative thereof that is effective to inhibit the growth of a fungal...
6034080 Use of Maillard reaction inhibitors for the treatment of amyloidosis-based disease  
Inhibitors of the Maillard reaction are useful in the treatment or prophylaxis of amyloidosis-based disease, particularly Alzheimer's disease. Particular examples include aminoguanidine and...
6022545 Usage of pathogen-killing foams  
This invention describes the effect of a means to prevent the sexual transmission of infectious pathogens of the vaginal and uterine wall in women, farm animals and pets. This discovery concerns a...
5985845 Methods for reducing mortality rates in poultry  
Poultry such as chickens and turkeys are treated with natamycin to reduce overall mortality and to reduce mortality rates due to the disease ascites.
5981499 Lesion-directed antibiotics in dry dosage forms for the treatment of shallow ulcers of the oral mucosa  
The invention provides a medicament for topically treating aphthous ulcers in the oral mucosa, and methods of use. The medicament comprises a troche or powder comprising a dry dosage of one or more...
5942495 Antibiotics  
The invention relates to an N-alkyl-N-glycosyl derivative of antifungal antibiotics of the polyene macrolide group of general formula 1(a), wherein M represents polyene macrolide antibiotics...
5939399 Polyene antibiotics, 3874 H1 to H6, processes for their preparation and use  
Novel polyene antibiotics, 3874 H1 to H6, processes for their preparation and use which are suitable for treating fungal diseases, trichomonad diseases, and for treating diseases associated with an...
5908834 Partricin derivatives in the prophylactic and/or curative treatment of fungal contamination of cell cultures and of tissues  
The use of ester and/or amide derivatives of partricin A and/or B to inhibit or forestall the growth of yeasts and molds in cell cultures of animal or vegetable origin, including hybridomas and...
5902579 Natamycin-containing streptomyces biomass and its use in animal feed  
Natamycin biomass comprising 5-60% natamycin, most preferably 25-60% natamycin, and methods for forming the biomass, are disclosed. The natamycin biomass can be mixed with compatible carrier to...
5898034 Psoriasis medication and application for remission and/or cure of plaque psoriasis  
A medication and application for the remission and/or cure of the disease of Psoriasis. Their are no other anti-fungal Psoriasis creams or medications of this type and style available on the market...
5880101 Clinical uses of polyene macrolides  
The present invention relates to the use of at least one polyene macrolide for the preparation of pharmaceutical compositions for the treatment of diseases that are associated with an impaired...
5877212 Molecular complex and control-release of alpha hydroxyacids  
Compositions comprising an alpha hydroxyacid or related acid and organic complexing agent having a molecular weight ranging preferably between about 100 and about 600 can form a control-release...
5874104 Treatment of systemic fungal infections with phospholipid particles encapsulating polyene antibiotics  
Formulations consisting of phospholipid small unilamellar particles encapsulating polyene antifungal antibiotics and methods for using such compositions to treat systemic fungal infections are...
5801144 Use of a compound for the manufacture of a medicament for the treatment of HIV infection  
Calcineurin antagonists are disclosed for use in the treatment of HIV infection. Preferred materials include cyclosporin A and FK 506.
5776904 Dispersion preparation  
Liquid dispersions are produced wherein amphotericin B, the methyl ester thereof, nystatin, trichomycin, primaricin and the like having a particle size of 10 μm or less are dispersed in a suitable...
5741782 Antibiotic cocktail and method of use  
An antibiotic cocktail for sterilizing tissue comprising amphotericin B and fluconazole as antifungal agents and a plurality of antibacterial agents. The agents are present in amounts effective to...
5599795 Method for treatment of idiopathic inflammatory bowel disease (IIBD)  
A new method for the prevention and treatment of Idiopathic inflammatory Bowel Disease (IIBD), including Crohn's Disease and Ulcerative Colitis, in human patients is provided. The key steps include...
5591438 Natamycin recovery  
A process for the recovery of high purity natamycin from fermentaion broth by extraction with methanol is disclosed. In one embodiment the process comprises the steps: (1) adding methanol to a...
5573765 Composition and method for treatment of vaginal yeast infections  
A composition for the treatment of vaginal yeast which promotes normal vaginal bacterial growth during treatment, comprising a yeast-inhibitory agent selected from one or more of the group...
5567685 Water-Soluble polyene conjugate  
A method for producing a substantially stable water-soluble polysaccharide conjugate of a polyene antibiotic is described. The method comprises the following steps: (a) activating the...
5534502 Process for producing fat emulsion  
Stable homogeneous fatty emulsions containing amphotericin B are prepared. According to one embodiment, amphotericin B is decrystallized using an acid and ethanol and then homogeneously dispersed...
5514662 Use of amphotericin B derivatives as protease inhibitors  
The invention is directed toward the use of amphotericin B and derivatives thereof as inhibitors of serine-proteases and for applying these inhibitors for the production of medicinal products...
5444052 Amphotericin B composition with enhanced fungal activity  
Fungal infections are treated by administering a combination of (a) amphotericin B, and (b) a glycerol ether selected from the group consisting of (i) HOCH 2 CHOHCH 2 OR, (ii) HOCH 2 ...
5441940 Process for the preparation of water soluble primycin and its components and pharmaceutical compositions containing them  
The invention relates to a process for the preparation of water soluble primycin and to the separation of its components of formulae (A 1 ) and (A 3 ) either as single components or as a mixture of...
5439891 Process for preparation of pharmaceutical composition with enhanced activity for treatment of tuberculosis and leprosy  
A new pharmaceutical composition for the treatment of tuberculosis and leprosy, said composition comprising piperine in combination with known antituberculosis or antileprosy drugs or the mixtures...
5434163 Treatment of Cryptococcus neoformans infection  
A method of treatment of Cryptococcus neoformans infection by administering to a patient in need thereof an effective amount of a benzimidazile compound.
5414014 Methods for efficacious removal of attached, sucking antropods from human dermis  
The present invention provides methods of using compositions containing local anesthetic compounds for facilitating the removal of sucking arthropods from the skin of a mammal; for reducing...
5389373 Preparation of oil-in-water emulsions of drugs  
A process for preparing an oil-in-water emulsion of a drug which is poorly soluble in water wherein the drug (e.g. amphotericin B) is dissolved in a solution of high or low pH prior to the...
5312813 Biofilm reduction method  
A method of killing microorganisms which form a biofilm on a tissue or implant surfaces in a patient, and which are refractory to a biocide at a dose which is effective to kill the microorganism in...
5298495 Partricin derivatives  
Derivatives of partricin and of its individual components, partricin A and B, wherein the mycosamine primary amino group forms an amide bond with the carboxy group of acids containing in addition a...
5244880 Stable aqueous solutions of prymicin and pharmaceutical and cosmetic compositions containing these solutions  
The invention relates to novel stable aqueous primycin solutions containing 0.5 to 1.75% by mass/volume of primycin sulfate or 2.5 to 9% by mass/volume of a complex of primycin N-methylpyrrolidone...
5231014 Fermentation process for producing natamycin  
A natamycin producing Streptomyces species ferments to produce natamycin. A spore suspension of the Streptomyces species is propagated in a predetermined medium to obtain a quantity of Streptomyces...
5229372 Control of poultry dactylariosis  
Post-hatch diseases in poultry caused by Dactylaria gallopava are prevented and treated by exposing the poultry environment to an effective quantity of natamycin.
5217707 Pharmaceutical composition and process for the preparation thereof  
The invention relates to a stabile, aqueous suspoemulsion containing as active ingredient 0.2-5 weight % of primycin, 5-25 weight % of propylene glycol, 0.5-5 weight % of non-ionic surface active...
5204330 Antifungal compounds  
A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein: R 1 is a group --CH 2 --X where X is hydrogen, halogen, --CN, --N 3 , --OC(O)R 5 , --S(O) n R 5 , --SH,...
5196344 Milk sample preservative  
An antimicrobial composition for the preservation of milk samples required for analysis. The composition comprises 2-bromo-2-nitropropane-1,3-diol and natamycin, in effective amounts to prevent...
5194266 Amphotericin B/cholesterol sulfate composition and method  
An amphotericin B composition containing particles of amphotericin B and cholesterol sulfate, in a molar ratio of between about 1:1 to 2:1. The particles, when stored in lyophilized form and...
5180713 Stabilized liposome/amphotercin B composition and method  
A method of administering a liposome/amphotericin B composition having a predetermined size distribution in 0.2-0.5 micron size range. The method includes preparing a suspension of heterogeneously...
5104857 Pseudo-primycin complexes, components and acid addition salts thereof  
The invention relates to antibacterial pseudo-primycin complexes of formula (I) ##STR1## to the components and acid addition salts thereof, as well as to the preparation of these compounds and to...
5104657 Combination preparations containing chloramphenicol, gentamicin and nystatin as active ingredients for the topical treatment of inflammatory skin disorders  
The invention relates to combination preparations containing chloramphenicol, gentamicin, nystatin and optionally a cortisone as active ingredients for the topical treatment of inflammatory skin...
5100876 16-decarboxy-16-hydroxy derivatives of amphotericin B  
Compounds of the formula (I), or pharmaceutically acceptable salts thereof: ##STR1## wherein R 1 is --CH 2 OH; R 2 is hydrogen or C 1 -8 alkyl; R 3 is hydrogen or an amine protection group; and...
Matches 51 - 100 out of 149 < 1 2 3 >