Matches 451 - 500 out of 511 < 1 2 3 4 5 6 7 8 9 10 11 >
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4780473 Bicyclic fungicides  
Compounds are disclosed having fungicidal activity and are of general formula I ##STR1## where at least three of A, C, D and E are --CX and the other is --CX or --N, where X is hydrogen, C...
4772600 Fused imidazoheterocyclic compounds and pharmaceutical compositions  
Imidazoheterocyclic compounds having the formula: ##STR1## wherein the A ring is pyridine in any of its four positions; B is carbonyl, thioxomethyl or hydroxymethylene; Z is hydrogen, halogen,...
4766130 2-phenyl-imidazopyridin-ones and also useful as cardiotonics and anti-hypertensives  
Compounds of the formula ##STR1## wherein A, B, C and D are --N, HN, R 3 N, OC, HC.tbd., HO--C.tbd. or R 3 SO 2 --O--C.tbd.; and R 1 and R 2 are substituents of various...
4766129 Pyrrolo[2,3-C]pyridines and their use as anti-hypertensive agents  
Compounds of the formula ##STR1## wherein R 1 is hydrogen, alkyl of 1 to 6 carbon atoms or phenyl(alkyl of 1 to 6 carbon atoms); R 2 is hydrogen, alkyl of 1 to 4 carbon atoms or phenyl(alkyl...
4758574 2-phenylimidazio (4,5-c) pyridines  
This invention provides for certain 2-phenylimidazo[4,5-c]pyridines, their pharmaceutical formulations, and their use as positive inotropic agents, bronchodilators, vasodilators, and anticoagulants.
4745121 Pyrazolo[3,4-b]pyridine-5-carboxamides and their use as anxiolytic agents  
This invention relates to pyrazolo[3,4-b]pyridine amides useful as anxiolytic agents.
4738970 Benzimidazolyl-thio-tetrahydroquinolines and anti-peptic ulcer compositions containing the same  
Novel tetrahydroquinoline derivatives and salts thereof and novel imidazopyridine derivatives and salts thereof, both having excellent anti-peptic ulcer activities, and are useful as treating...
4722929 Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same  
The invention relates to novel 2-phenyl-imidazoles of the formula ##STR1## and the tautomers and acid addition salts thereof, particularly the pharmacologically acceptable acid addition salts,...
4720501 2-(2-thienyl)-imidazo(4,5-c)pyridine derivatives and salts thereof useful in the treatment of myocardial insufficiency  
The invention relates to new 2-(2-thienyl)imidazo(4,5-c)pyridine derivatives of the formula ##STR1## wherein R 1 denotes lower alkyl, R 2 denotes hydrogen or methyl and n denotes 0 or 1, and...
4716160 Certain 7-amino-pyrazolo[4,3-b]pyridines useful in treating inflammatory and allergic disorders  
Compounds of formula (I) ##STR1## wherein: R is hydrogen or C 1 -6 alkyl; R 1 and R 2 are both hydrogen; or R 1 is hydrogen, C 1 -6 alkyl; and R 2 is CN; CR 5 R 6 Y where R 5 and R 6 ...
4714762 Antiarteriosclerotic substituted benzimidazol-2-yl-and 3H-imidazo[4,5-b]pyridin-2-yl-phenoxy-alkanoic acids and salts and esters thereof  
Novel substituted benzimidazol-2-yl-phenoxyalkanoic acids, salts and esters thereof and 3H-imidazo[4,5-b]pyridin-2-yl phenoxy-alkanoic acid, salts, and esters which are useful as...
4670432 Pyrazolopyridine derivatives useful in treating inflammation and allergic conditions  
A compound of formula (I) or a salt thereof: ##STR1## wherein: R 1 is hydrogen, C 1 -6 alkyl or phenyl optionally substituted by halogen, CF 3 , C 1 -4 alkoxy or C 1 -4 alkyl; R 2 is hydrogen...
4654350 Gaba-agonistic imidazo(4,5-c)pyridines useful as pharmaceuticals  
Imidazo(4,5-c)pyridines of the formula ##STR1## wherein X is O, S or NH; Y is --NR 2 --CHN-- or --NCH--NR 2 --; R 1 is 1-benzothienylmethyl, naphthylmethyl, or benzyl which is mono-...
4634704 Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines  
Five membered heterocyclic ring containing N-(bicyclic heterocyclyl)-4-piperidinamines having histamine and serotonine antagonistic activity which compounds are useful agents in the treatment of...
4596830 Novel derivatives of 2-(2-thienyl)-imidazo[4,5-b]-pyridines and their pharmaceutically acceptable salts  
The invention relates to new therapeutically valuable derivatives of 2-(2-thienyl)-imidazo[4,5-b]pyridines of the general formula ##STR1## in which R is methyl or ethyl, R 1 is hydrogen or methyl...
4582837 Imidazo[4,5-b] and [4,5-c]pyridine derivatives having cardiotonic activity  
There are disclosed novel imidazole derivatives of the formula ##STR1## and derivatives of the formula ##STR2## the tautomers thereof, and non-toxic, pharmacologically acceptable addition salts...
4579853 2-Cyano-imidazopyridine derivatives and their use as fungicides  
The invention relates to new 2-cyanoimidazopyridine derivatives. These compounds have the formula (I): ##STR1## in which: R 1 represents an optionally halogenated lower alkyl or cycloalkyl radical...
4576952 Pyrazolopyridine derivatives and their use as anti-inflammatory and/or anti-allergic agents  
Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein: R 1 is hydrogen, C 1 -6 alkyl or phenyl optionally substituted by halogen, CF 3 , C 1 -4 alkoxy or C 1 -4...
4568680 2-Phenyl-imidazo[4,5-c]pyridinones useful as cardiotonic agents  
Compounds of the formula ##STR1## wherein one of A and B is methenyl (--CH) and the other is carbonyl; R 1 is (alkyl of 1 to 3 carbon atoms)mercapto, (alkyl of 1 to 3 carbon atoms)sulfinyl or...
4559348 5- And/or 7-substituted pyrazolo-[4,3-b]-pyridines and their use as antiinflammatory agents  
Compounds of the formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein: the first of R 1 and R 2 is hydrogen, C 1 -4 alkyl or phenyl optionally substituted by one or two...
4552883 Pyrazolo[3,4-b]pyridine carboxylic acid esters and their pharmaceutical use  
Compounds of the formula (I): ##STR1## wherein R 1 , R 3 , R 4 , R 5 and R 6 have defined values and the N-oxides at the 7-position of the pyrazolo[3,4-b]pyridine ring system and the...
4545992 Pharmaceutical preparations  
A pharmaceutical preparation for external use which comprises a solution of a non-steroid antipholgistic analgesic agent which is dissolved in at least one adjuvant selected from the group...
4537905 Fungicidally active substituted oximinoacetanilides  
Substituted oximinoacetanilides of the general formula ##STR1## in which R 1 denotes an alkyl or alkoxy group or a halogen atom, R 2 denotes a hydrogen or halogen atom or an alkyl or...
4515796 Certain naphthalenyl imidazo compounds and their pharmaceutical use  
This invention provides for certain naphthalenylimidazo compounds, their pharmaceutical formulations, and their use as positive inotropic agents, bronchodilators, vasodilators, and anticoagulants.
4470986 Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors  
Disclosed are e.g. 5-(tetrazolylalkyl, hydroxycarbamoylalkyl)imidazo[1,5-a]-pyridines, and methods of synthesis. Said compounds are useful as selective thromboxane synthetase inhibitors for the...
4450164 Imidazo[1,2-A]pyridines and use  
This invention relates to imidazo[1,2-a]pyridine derivatives which are useful in the treatment of peptic ulcer diseases.
4421755 Method of treating coronary heart disease with imidazo(4,5-B)pyridines  
Pharmaceutical compositions containing, as an active ingredient, a compound of the formula ##STR1## wherein R 1 is alkoxy of 1 to 4 carbon atoms, and R 2 is (alkyl of 1 to 4 carbon atoms)...
4391811 2-Amino-6-(pyridinyl)-3H-imidazo[4,5-b]pyridines and their cardiotonic use  
2-(NB)-3-R-6-PY-5-Q-3H-imidazo[4,5-b]pyridines (I) and salts, useful as cardiotonics, where NB is amino or dimethylamino, R is lower-alkyl, Q is hydrogen or lower-alkyl, and PY is 4- or 3-pyridinyl...
4386092 Heterocyclic-substituted oxoalkanoic acid derivatives  
A heterocyclic-substituted oxoalkanoic acid derivative having immunomodulatory activities of the formula: ##STR1## wherein R 1 is hydrogen, lower alkyl, phenyl which may be substituted by at least...
4386093 (±)3-Deazaaristeromycin and uses  
(±)3-Deazaaristeromycin, also known as (±)-4-amino-1-[(1α, 2β, 3β, 4α)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]imidazo[4,5- c]pyridin e, utilized as a novel antiviral agent and inhibiting...
4375467 5-(Pyridinyl)-1H-pyrazolo[3,4-b] pyridines and their cardiotonic use  
1-R-3-R'-5-PY-1H-pyrazolo[3,4-b] pyridines (I) or acid-addition salts thereof, which are useful as cardiotonics, are prepared by reacting a α-PY-βdimethylamino-acrolein with...
4364948 Pyrazolo[3,4-b]pyridine compounds  
Certain pyrazolo[3,4-b]pyridine compounds which are useful for their activity in the central nervous system of warm-blooded animals, of the following formula (I) ##STR1## wherein R 1 is lower...
4363808 N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines  
3-Phenoxy-2-hydroxypropylamines having an N-benzimidazolyalkyl substituent and similar compounds are described herein. They are obtained by the reaction of the appropriate imidazole-1-alkanamine...
4361568 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-amines and their cardiotonic use  
1-R-3-(NB)-5-PY-6-Q-1H-pyrazolo[3,4-b]pyridines or pharmaceutically-acceptable acid-addition salts thereof, which are useful as cardiotonics, are prepared by reacting a...
4358453 1,2,4-Triazolo[4,3-a]pyridines  
There are disclosed herein certain 1,2,4-triazolo-[4,3-a]pyridine compounds which are useful in the treatment of peptic ulcer diseases.
4358454 1,3,4-Triazolo[1,5-a]pyridines  
There are disclosed herein certain 1,3,4-triazolo[1,5-a]pyridine compounds which are useful in the treatment of peptic ulcer diseases.
4353909 6-Hydroxy-2-phenyl-imidazo[4,5-b]pyridines and salts thereof  
Compounds of the formula ##STR1## wherein R is methylsulfinyl or methylsulfonyl, their 3H-tautomers, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds are...
4340597 1-Substituted-4-aryl-1,2,5,6-tetrahydro and hexahydropyridines  
Disclosed herein are certain 1-substituted-4-aryl-1,2,5,6-tetrahydro and hexahydro triazolo pyridines which are useful as analgesics.
4336257 Novel 2-pyridylbenzimidazole compounds  
Novel alkylsubstituted 2-pyridylimidazoles, halosubstituted-2-pyridylbenzimidazoles, and 2-pyridylimidazopyridines are disclosed. The compounds have pharmaceutical utility as xanthine oxidase...
4330543 Imidazoazines and imidazodiazines  
Novel imidazopyridines, -pyrazines, -pyrimidines and -pyridazines having a 3-amino-2-OR-propoxy substituent, are disclosed. The compounds have β-adrenergic blocking activity.
4327100 2-(Alkoxy-phenyl)-imidazo(4,5-b)pyridines and salts thereof  
Compounds of the formula ##STR1## wherein R 1 is alkoxy of 1 to 3 carbon atoms; and R 2 is (aralkylsulfinyl of 7 to 9 carbon atoms)-(alkoxy of 2 to 3 carbon atoms); or (unsubstituted, mono-,...
4293554 Method of treating asthma  
A method of treating asthma in a warm-blooded animal using the compound 6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3(2H)-one.
4276293 Compositions and their preparation  
2-R 2 -3-R 3 -6-PY-5-Q-3H-imidazo[4,5-b]pyridines (I) or 1-R 1 -2-R 2 -6-PY-5-Q-1H-imidazo[4,5-b]pyridines (IA) or pharmaceutically-acceptable acid-addition salts thereof, where Q and R 2 are...
4265895 1,2-Dihydro-5-pyridinyl-3H-pyrazolo[3,4-b]pyridin-3-ones and their use as cardiotonics  
1,2-Dihydro-1-R-5-PY-6-Q-3H-pyrazolo[3,4-b]pyridin-3-ones or pharmaceutically-acceptable acid-addition salts thereof, which are useful as cardiotonic agents, are prepared by reacting lower-alkyl...
4264603 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridine-3-amines, their use as cardiotonics and their preparation  
1-R-5-PY-6-Q-1H-pyrazolo[3,4-b]pyridin-3-amines or pharmaceutically-acceptable acid-addition salts thereof, which are useful as cardiotonics, are prepared by reacting a...
4260614 4-(2-(1H-Imidazol-1-ylmethyl)-1,3-dioxol an-4-yl)methoxypyrazolo(3,4-b)pyridines  
Compounds are provided having the formula ##STR1## wherein R 1 is hydrogen, lower alkyl; substituted or unsubstituted phenyl-lower alkyl; substituted or unsubstituted phenyl; substituted or...
4260621 3-Amino-4-phenyl-6-piperidino-1H-pyrazolo[3,4-b]-pyridines and salts thereof  
Compounds of the formula ##STR1## wherein R 1 is unsubstituted, mono-substituted or di-substituted piperidino, where the substituents are selected from the group consisting of methyl,...
4247556 7-Azabenzimidazoles with basic side chains and use thereof  
There are prepared 7-azabenzimidazoles of the formula ##STR1## where R 1 and R 2 are the same or different and are hydrogen, C 1 -C 6 -alkyl or C 2 -C 6 -alkanol or --NR 1 R 2 is a 5 to 7...
4244953 Substituted 6-phenyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyridines  
This disclosure describes novel substituted 6-phenyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridines and their use as agents for treating anxiety.
4232029 1-Hydroxyimidazole-5-methanamine derivatives  
1-Hydroxyimidazole-5-methanamine derivatives characterized by having a lower alkyl group at positions N, N and 5 of the latter derivatives as well as having various substituents at position 2 of...
Matches 451 - 500 out of 511 < 1 2 3 4 5 6 7 8 9 10 11 >