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8168597 |
Method for treating cystic fibrosis
The present invention is directed to a method for treating cystic fibrosis. The method comprises the steps of: identifying a patient suffering from cystic fibrosis, and administering to the patient...
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8153601 |
Azithromycin-containing aqueous pharmaceutical composition and a method for the preparation of the same
The invention provides an azithromycin-containing aqueous pharmaceutical composition, which comprises at least one member selected from the group consisting of azithromycin, and pharmaceutically...
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8097266 |
Solvent systems for pour-on formulations for combating parasites
This invention relates to pharmaceutical and veterinary formulations providing enhanced solvency and stability for pharmaceutical and veterinary agents for administration to animals, especially...
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8093219 |
Topical application of ivermectin for the treatment of dermatological conditions/afflictions
Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most...
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8080530 |
Topical application of ivermectin for the treatment of dermatological conditions/afflictions
Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most...
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8067382 |
Anthelmintic composition
The invention relates to a novel formulation having the advantage of including triclabendazole in solution. In addition a further anthelmintic may be included. The formulation is made by mixing the...
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8053418 |
Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative
A novel compound that has antimicrobial activity against penicillin-resistant Streptococcus pneumoniae, and an anti-penicillin resistant pneumococci agent that includes the compound as an active...
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8048861 |
Pesticidal formulations
The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic...
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8017589 |
Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4″-or 4′-position
What is described are a compound of the formula wherein n is 0 or 1; A-B is —CH═CH— or —CH2—CH2—;R1 is C1-C12-alkyl, C3-C8-cycloalkyl or C2-C12-alkenyl;R2 is for example C1-C12-alkyl, C2-C12-alke...
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7939565 |
Active substance combinations having insecticidal and acaricidal properties
The present invention relates to novel insecticidally and acaricidally active compound combinations of...
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7906127 |
Insecticidal mixture containing gamma-cyhalothrin
An insecticidal mixture of gamma-cyhalothrin [(S)-α-cyano-3-phenoxybenzyl (Z)-(1R,3R)-3-(2-chloro-3,3,3-tzifluoro-1-propenyl)-2,2-dime
thylcyclopropanecarboxylate] and one or more further active ...
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7807151 |
Probiotic, lactic acid-producing bacteria and uses thereof
The present invention discloses compositions and methodologies for the utilization of probiotic organisms in therapeutic compositions. More specifically, the present invention relates to the...
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7781411 |
Derivatives of avermectin, avermectin monosaccharide and avermectin aglycone
Certain derivatives of avermectin, avermectin monosaccharide and avermectin aglycone, having on the 4″, 4′ or 13 position, respectively, a 6-membered cyclic acetal with a substituent on pos...
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7772194 |
Pesticidal formulations
The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic...
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7754696 |
Application of water and organic solvent soluble Ivermectin for topical and oral use
A stable, palatable solution of Ivermectin in water is provided for the mass medication of animals. The present formulation does not require the use of benzyl alcohol and is stable indefinitely in...
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7732416 |
Avermectins substituted in the 4″-position having pesticidal properties
What is described are a compound of the formula in whichR1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl;R2 is H, unsubstituted or mono- to pentasubstituted C1-C12alkyl or unsubstituted or mono-...
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7704961 |
Avermectins and avermectin monosacharides substituted in the 4′-and 4″ position having pesticidal properties
Described is a compound of the formula (I) wherein the bond between carbon atoms 22 and 23 is a single or double bond; m is 0 or 1; R1, is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; and either...
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7687471 |
Benzimidazole non-aqueous compositions
The present invention provides a stable veterinary oral composition which comprises one or more surfactants, a water-miscible solvent, optionally an oil and an effective amount of each of a...
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7687470 |
Avermectin and avermectin monosaccharide substituted in the 4″- and 4″ position respectively
Avermectin and avermectin monosaccharaide compounds, derivatives, and compositions thereof are provided as well as processes for preparing such compounds, derivatives, and compositions....
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7678773 |
Salts of avermectins substituted in the 4″-position and having pesticidal properties
A compound of formula wherein X− is an anion;n is 1, 2, 3 or 4;R1 is C1-C12alkyl, C3-C8cycloalkyl; or C2-C12alkenyl;R2 is hydrogen, unsubstituted or substituted C1-C12alkyl or C2-C12alkenyl;R3 is h...
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7674475 |
Endoparasiticidal gel composition
A homogenous, clear, veterinary gel composition which has a broad spectrum of efficacy against endoparasites over a prolonged period of time and which allows for higher concentrations of a mixture...
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7648711 |
Dimethicone-containing sustained release injection formulation
A sustained release formulation by using dimeticone as the dispersion medium, which includes active ingredient (e.g., drugs against parasites, insecticides, NSAIDs, antibiotics, sex hormone like...
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7645816 |
Water-soluble compositions of bioactive lipophilic compounds
Water-soluble compositions comprising a lipophilic compound and a solubilizing agent of the general formula: {X—OOC—[(CH2)n—COO]m}p—Y (I) wherein: X is a residue of a hydrophobic moiety,Y is a re...
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7638545 |
Anthelmintic composition
A formulation having triclabendazole in solution. In addition a further anthelmintic may be included. The formulation is made by mixing the abamectin and benzyl alcohol and mixing this with...
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7632820 |
Avermectin and avemectin monosaccharide derivatives substituted in the 4″- or 4′-position having pesticidal properties
Disclosed are compounds of the formulain which n is 0 or 1; X—Y is —CH═CH— or —CH2—CH2—; Z is —C(═O)—, —C(═S)— or —SO2—; R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; and R2 is R3-Z...
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7605134 |
4″-Deoxy-4″-(s)-amino avermectin derivatives
A description is given of compounds of the formula which in the 4″-position has the (S)-configuration and wherein R1 is C1-C12alkyl, C3-C8cycloalkyl; or C2-C12alkenyl; R2 is hydrogen, optionally s...
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7585887 |
Active agent combinations with insecticidal and acaricidal properties
The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula in which the groups W, X,...
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7582612 |
Multi-action anthelmintic formulations
The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus tetrahydropyrimidines. An...
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7563773 |
Anthelmintic oral homogeneous veterinary pastes
This invention provides for, inter alia, oral homogeneous veterinary pastes for the treating, controlling and preventing of endo- and ectoparasite infections in warm-blooded animals or birds, such...
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7550440 |
Topical application of ivermectin for the treatment of dermatological conditions/afflictions
Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most...
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7521429 |
Avermectin B1 monosaccharide derivatives
A compound of formula (I) wherein the bond between carbon atoms 22 and 23 may be a single or a double bond; R1 is C1-C12alkyl, C3-C8cycloalkyl, or C2-C12alkenyl; R2 and R3 are, for example,...
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7396820 |
Anthelmintic formulations
The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus...
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7396819 |
Anthelmintic formulations
The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus hexahydropyrazinoisoquinolines...
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7378399 |
Avermectins substituted in the 4″ and 4′-positions having pesticidal properties
What is described are a compound of the formula (I) Wherein A-B is —CH═CH— or —CH2—CH2—; n is 0 or 1; R1, is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 and R3 for instance are either, (i)...
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7368435 |
Topical endoparasiticide and ectoparasiticide formulations
A topical formulation having significant parasiticidal activity effective against endoparasites and/or ectoparasites such as heartworms, mites, fleas, ticks, flies is provided, which can be safe to...
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7282487 |
Method for treating bacterial infections in horses or pigs with tilmicosin
The invention relates to methods of treating a bacterial infection in a horse or a pig. The method involves administering to the horse or pig a composition comprising (i) a salt made from...
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7250402 |
Avermectin derivatives
A compound represented by the general formula (I) or a salt thereof: wherein represents —CH═CH—, —CH2—CH2— or the like, between R1 and the carbon atom at 4′-position represents a single bond o...
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7247617 |
Sixteen-member macrolide antiinfective agents
Sixteen membered macrolide anti-infective agents having a structure according to formula I where R1, R2, R3, R4, R5, and R6 are as defined herein, and related compounds are disclosed.
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7195773 |
Pesticidal composition
A pesticidal composition comprising a pesticidally effective amount of at least one of a pyridic compound of the formula (I) or it salt and at least one of other pesticides: wherein Y is a...
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7119076 |
Preventives or remedies for endometriosis or uterine myoma
A drug effective for prevention and therapy of endometriosis and hysteromyoma is disclosed. The drug for prevention and/or therapy of endometriosis and/or hysteromyoma according to the present...
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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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7064108 |
Topical ivermectin composition
A topical gel composition comprising between about 0.005 and 1.0% ivermectin, between about 30 and 40% of a pharmaceutically acceptable alcohol, between about 30 and 40% of a pharmaceutically...
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7037523 |
Controlled release compositions for macrolide antimicrobial agents
The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred...
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6998131 |
Spot-on formulations for combating parasites
In particular this invention provides for spot-on compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (1) a composition comprising (A) an...
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6991801 |
Topical anthelmintic veterinary formulations
This invention provides for inter alia, topical anthelmintic formulations which comprise a pharmaceutically active combination consisting of at least one macrocyclic compound and at least one...
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6962713 |
Spot-on formulations for combating parasites
In particular this invention provides for spot-on compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (1) a composition comprising (A) an...
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6919317 |
Pharmaceutical composition comprising squalene epoxidase inhibitor and macrolide immunomodulator
Synergistic combinations of a squalene epoxidase inhibitor such as terbinafine and a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro, 33-desoxyascomycin are provided,...
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6914051 |
Penetrating antibiotic gel for soft tissue diseases
A penetrating antibiotic gel for treating pain, inflammation and other pathological conditions affecting musculoskeletal tissues and other soft tissues of the body. The composition includes an...
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6903052 |
Nematicidal compositions and methods
The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes that parasitize animals can also be controlled...
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6872708 |
Local injection prescription
A local injection prescription that disperses a malignant tumor to decrease the size of the tumor or terminate the tumor. The local injection prescription is produced by dissolving an organic...
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