|
Match
|
Document |
Document Title |
|
|
5556855 |
N-heterocyclic substituted salicylic acids
A compound of the formula Het--NR--SO 2 --Ph 2 --A--Ph 1 (COOH)(OH) and tautomic form, salts, solvates, C 1 -6 alkyl esters and pharmaceutical compositions of the compound. Ph 1 and Ph 2 are...
|
|
|
5554618 |
Intravenously administrable aqueous solution
An intravenously administrable, aqueous solution of a water-soluble, physiologically tolerable salt of sulfametrole and of trimethoprim, in which malic acid, L-serine and/or L-threonine are present...
|
|
|
5547955 |
High fructose insecticide bait compositions
This invention relates to the discovered that in many strains of the German cockroach [Blattella germanica (L.)], feeding is inhibited by high glucose levels, conversely, feeding of this strain of...
|
|
|
5543433 |
Azine-substituted phenylacetic acid derivatives and fungicides containing these
Compounds of the formula I ##STR1## where X is hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, cyano or nitro, Y is an amino, methylamino or dimethylamino group, Z is a group CHCH 3 ,...
|
|
|
5541199 |
Chroman-2-ylmethylamino derivatives
Compounds of the formula: ##STR1## in which n is one of the integers 1, 2, 3,or 4; m is one of the integers 0 or 1; R is ##STR2## or a pharmaceutically acceptable salt thereof, are inhibitors of...
|
|
|
5541186 |
Sulfonylaminopyrimidines
A compound of the formula ##STR1## wherein R 1 to R, R a , R b X, Y, Z, m and n have the significance given in the description, can be used as medicaments, especially for the treatment and...
|
|
|
5532259 |
Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides, pharmaceuticals containing these compounds and their use
Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides, pharmaceuticals containing these compounds and their use Isoxazole-4-carboxamide derivatives and hydroxyalkylidene-cyanoacetamide...
|
|
|
5525604 |
4-aminopyrimidine derivatives
A 4-aminopyrimidine of the formula (I): ##STR1## wherein A is a bond, C1-4 alkylene or C1-4 oxyalkylene; Y is a bond, C1-4 alkylene, C1-4 alkyleneoxy, C1-4 alkoxyphenylene or...
|
|
|
5506263 |
Benzyl derivatives and pesticides containing them
Benzyl derivatives of the formula I ##STR1## where A is CH 2 , CHCl, CH-alkyl, CH-alkoxy, CH-alkylthio or N-alkoxy, B is OH, alkylthio, alkoxy or alkylamino, U, V, W are hydrogen, halogen,...
|
|
|
5502063 |
1-halopyridin-4-amino-4-alkylpiperidines
The present invention relates to novel heteroarylpiperidines of formula (I): ##STR1## in which Hal is a halogen atom, Alk is a C 1 -C 4 alkyl group and X, Y and Z are each --CH and their...
|
|
|
5494934 |
Guanidine compounds
A compound of formula (I): ##STR1## in which: R 1 represents substituted or unsubstituted phenyl or (C 3 -C 7 ) cycloalkyl, R 2 represents trifluoromethyl or (C 3 -C 4 ) cycloalkyl, A...
|
|
|
5491147 |
Tri-substituted phenyl derivatives and their use in pharmaceutical compositions and methods of treatment
Compounds of formula (1) ##STR1## are described wherein Y represents a halogen atom or a group --OR 1 , where R 1 is an optionally substituted alkyl group; R 2 represents an optionally...
|
|
|
5484788 |
Buspirone as a systemic immunosuppressant
A method for suppressing an immune response in a mammal by systemically treating the mammal with an effective amount of buspirone that is capable of inhibiting classic contact hypersensitivity...
|
|
|
5482957 |
Azole derivatives, process for their preparation and their use
Azole derivatives, process for their preparation, and their use Azole derivatives of the formula (I) ##STR1## in which A, L, O, R 1 , X, Y, Z and q have the meanings given, process for their...
|
|
|
5480884 |
Compounds having a guanidine structure
Compounds are provided useful for promoting growth, repair and regeneration of a neuronal axon and for treating neuropathies and myopathies having formula I ##STR1## wherein R 2 , R 3 and R 4 ...
|
|
|
5470856 |
Tetrahydropyrimidine derivatives
The invention is concerned with a tetrahydropyrimidine derivative having formula I ##STR1## wherein R 1 is hydrogen; R 2 is hydrogen, a lower alkyl group, or lower acyl; or R 1 and R 2 ...
|
|
|
5466695 |
Method for stimulating hair growth with cationic derivative of minoxidil using therapeutic iontophoresis
This invention relates to a method of applying a cationic derivative of Minoxidil which is transported by means of iontophoresis to hair follicles where the cationic derivatives promote hair...
|
|
|
5462944 |
Fungicidal composition and method of combating fungi
Spiroheterocyclic compounds having fungicidal activity are disclosed having the formula: ##STR1## in which X is O or CH 2 ; R 1 is hydrogen or optionally substituted alkyl, cycloalkyl, haloalkyl,...
|
|
|
5455246 |
Piperidine derivatives
Compounds of formula I, Ia or Ib and pharmaceutically acceptable salts thereof, useful in the treatment of neuropsychiatric disorders such as psychoses; pharmaceutical compositions comprising a...
|
|
|
5447934 |
Anti-allergic thiadiazolo [4,3-a]pyridine derivatives
Compounds of the formula I ##STR1## in which X 1 and X 2 the same or different, signify hydrogen, a C 1 - to C 6 -alkyl radical or a halogen atom or, insofar as they stand in neighbouring...
|
|
|
5439908 |
Diazinyl butyric acid amides and esters
Compounds of the formula ##STR1## wherein A is a substituted or unsubstituted, aromatic or non-aromatic, monocyclic or bicyclic, heterocyclic radical that is bonded by way of a carbon atom to X;...
|
|
|
5439912 |
2-phenylamino-4-cyano-pyrimidines
Compounds of formula ##STR1## wherein R 1 is hydrogen, 3-fluorine or 4-fluorine, and R 2 is C 1 -C 4 alkyl, halo- or hydroxy-substituted C 1 -C 2 alkyl, C 3 -C 6 cycloalkyl or C 3 -C 6 ...
|
|
|
5428039 |
Method for electively achieving reversible hyperpolarized cardiac arrest
While performing cardiopulmonary bypass, the aorta is cross-clamped and the beating heart is stopped by introducing of an ATP-dependent potassium channel opening agent. The infusion into the...
|
|
|
5426110 |
Pyrimidinyl-glutamic acid derivatives
The present invention provides novel pyrimidinyl-glutamic acid derivatives and intermediates thereto. Further provided are methods for inhibiting dihydrofolate reductase in mammals and for treating...
|
|
|
5420164 |
Cycloalkylurea compounds
A cycloalkylurea compound of the formula (I): ##STR1## wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof, which compound inhibits ACAT and is...
|
|
|
5403845 |
Muscarinic agonists
Substituted 1,4,5,6 -tetrahydropyrimidine compositions, substituted 1,2,3,6 -tetrahydropyrimidine compositions and substituted 3,4,5,6 -tetrahydropyridine compositions are disclosed. They are...
|
|
|
5397781 |
Pyrimidine derivatives
The present invention relates to novel 5-(ω-substituted amino-alkanoyl amino)pyrimidine derivatives, processes for producing the derivatives, and pharmaceutical compositions containing said...
|
|
|
5391565 |
Oxazolidine dione derivatives
Compounds of the formula: ##STR1## or tautomeric forms and a pharmaceutically acceptable salt, and pharmaceutically acceptable solvates thereof, wherein: A 1 is a substituted or unsubstituted...
|
|
|
5389663 |
1-(1h-1,2,4-triazole-yl)-2-propanol compounds
An azole compound represented by the formula (I): ##STR1## wherein X is a nitrogen atom; Ar is a phenyl group substituted by halogen or a halogenated C 1 -4 alkyl group; R 1 and R 2 independently...
|
|
|
5389636 |
Method of combating venturia
The fungal disease Venturia, especially Venturia inaequalis, can be combatted using 2-anilino-4,6-dimethylpyrimidine.
|
|
|
5385902 |
Iodopropargylated oxalic derivatives as antimicrobial agents
Antimicrobial compounds of the formula ##STR1## wherein A is selected from the group consisting of alkyl; phenyl; alkoxy; phenoxy; benzyloxy; monoalkylamino; dialkylamino; cyclic amino, anilino;...
|
|
|
5376659 |
Substituted guanidine and amidine compounds, and fungicidal use
The present invention relates to novel substituted guanidine and amidine compounds, their preparation and their use in the kill and control of fungal organisms which infest plants.
|
|
|
5373012 |
5-fluoro-2,4,6-pyrimidinetriamine compounds
A 5-fluoro-minoxidil compound and compositions are disclosed which are useful in the treatment of hair growth and cardiovascular disorders. The 5-fluoro-minoxidil compounds have been shown to have...
|
|
|
5373006 |
Combination of derivatives of 1,8-hydroxy and/or acyloxy anthracene or anthrone and of pyrimidine derivatives for inducing and stimulating hair growth and reducing loss thereof
A composition comprising a combination intended to induce and to stimulate hair growth and to reduce its loss, characterized in that it comprises: (a) a component (A) containing at least one...
|
|
|
5371091 |
Heteroaromatic amine thrombin inhibitors
Sulfonamide thrombin inhibitors are provided which have the structure ##STR1## including all stereoisomers thereof, wherein n is 1, 2 or 3; m is 0, 1 or 2; R 1 and R 2 are independently H, lower...
|
|
|
5360804 |
Multicomponent agent or kit for preparing the sulpho-conjugated form of pyridino, pyrimidino or triazino N-oxide compounds and method of use
Multicomponent agent or kit for preparing the sulpho-conjugated form of pyridino, pyrimidino or triazino N-oxide compounds and method of use. The present invention relates to a multicomponent agent...
|
|
|
5358945 |
Pyrimidine compound and pharmaceutically acceptable salts thereof
The present invention relates to pyrimidine compounds represented by the formula ##STR1## (wherein X is a substituted or a cyclic amino group and Y is a substituted amino group or a substituted...
|
|
|
5336678 |
Use of minoxidil for treating erectile impotence
A method of treatment of human erectile impotency by topical administration to the penis of a topical composition containing 0.1 to 10% minoxidil.
|
|
|
5332745 |
Tetrahydropyrimidine derivatives
The invention provides a fungicidal composition comprising a carrier and, as active ingredient, certain tetrahydropyrimidine derivatives of the general formula ##STR1## or an acid-addition salt or...
|
|
|
5330985 |
2-amino-N- [[4-(aminocarbonyl)pyrimidin-2-yl]amino]-alkyl]pyrimidine-4-carboxamide derivatives, their preparation and pharmaceutical compositions containing them
A compound which is a pyrimidine-4-carboxamide derivative of the general formula (I) ##STR1## in which n is 0 or 1, m is 0 or 1, R 1 represents a methyl group when R 2 represents a...
|
|
|
5328913 |
Minoxidil analogs as inhibitors of cell proliferation and lysyl hydroxylase
The present invention relates to a method of inhibiting cell proliferation and lysyl hydroxylase expression. The method involves the use of minoxidil derivatives. The inhibitory activity of hydroxy...
|
|
|
5326564 |
Resealable cosmetic product
A cosmetic product is provided that includes a cosmetic composition and a container for storing same. The container has a first and second section. Each section is defined by a hemispheroidal...
|
|
|
5324731 |
Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated
A method of inhibiting growth, transformation and/or metastasis of mammalian cells, particularly epithelial cells, in which activity of at least one enzyme, which participates in purine metabolism...
|
|
|
5321030 |
Creatine analogs having antiviral activity
The present invention relates to the use of analogs of creatine, such as cyclocreatine, as antiviral agents. Analogs of creatine can be used as antiviral agents against a variety of viruses,...
|
|
|
5318975 |
5-pyrimdineamine derivatives
This invention relates to novel 5-pyrimidineamine derivatives. The compounds of the invention exhibit cardiovascular properties, particularly mixed vasodilative, selective venous and arterial...
|
|
|
5317021 |
3-mercapto-glutamic acid derivatives
Amino acid compounds of the formula: ##STR1## wherein the various symbols are as hereinafter described, which have inhibiting effect on enkephalinase.
|
|
|
5314891 |
Benzenesulphonamide derivatives
The invention concerns benzenesulphonamide derivatives of the formula I ##STR1## wherein R 1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; R 2 and R 3 together form --A 2 --X 2 --A 3 --...
|
|
|
5310578 |
Deposition of cosmetically functional material onto pigments and fillers
A process for coating the surface of pigment and filler particles with an oleaginous and cosmetically functional material, characterized in that an aqueous suspension of the pigment or filler is...
|
|
|
5304555 |
Pyrimidines and pharmaceutically acceptable salts thereof useful in treatment of neurological disorders
This invention provides novel pyrimidines or their pharmaceutically acceptable salts thereof and process for preparation thereof. The novel compounds are useful for neurological diseases of the...
|
|
|
5302605 |
Picoline oxides
Novel 3-picoline-N-oxides of formula I ##STR1## wherein R 1 and R 2 independently of each other are hydrogen or halogen, R 3 is hydrogen or C 1 -C 4 alkyl, n is the number two or three, and Y...
|