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8173608 |
Compound having cyclic structure and use thereof
The present invention relates to a compound represented by the following formula (1′) wherein R is an aldopyranose residue, R2 is a C2-18 hydrocarbon group optionally having substituent(s), R3 is a...
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8173142 |
Pharmaceutical compositions of drugs and neutralized acidic polymers
Pharmaceutical compositions comprised of low-solubility and/or acid-sensitive drugs and neutralized acidic polymers are disclosed.
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8138158 |
Compositions and methods for therapy for diseases characterized by defective chloride transport
Compositions and methods for therapy of cystic fibrosis, asthma, and other conditions characterized by defective chloride transport are provided. The compositions comprise one or more compounds...
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8128948 |
Compositions and methods for attracting Anastrepha species
A composition containing suspensolide and optionally at least one of γ-hydroxy acid of epianastrephin, γ-hydroxy acid of anastrephin, 2,6-dimethyl-6-vinyl-cyclohexeneacetic acid, β...
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8129337 |
Compositions comprising epigallocatechin gallate and protein hydrolysate
The present invention describes a composition comprising EGCG and a protein hydrolysate.
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8088743 |
Methods for treating obesity employing an SGLT2 inhibitor
Methods are provided for treating obesity or causing weight loss in a mammalian subject or patient, wherein a therapeutically effective amount of an SGLT2 inhibitor alone or optionally in...
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8088745 |
Methods for assaying alpha-L-iduronidase enzymatic activity
Methods for assaying α-L-iduronidase enzymatic activity and methods for screening newborns for Mucopolysaccharidosis Type-I.
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8084430 |
ENT-kaurene diterpene compound and its derivatives, their preparation and their use
Novel ent-kaurene diterpene compound and its derivatives, their preparation methods and their use. ent-Kaurene diterpene in the present invention could be used as desired intermediates for...
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8084431 |
Method for inhibiting activation of macrophages, inhibiting formation of osteoclasts, inhibiting function of osteoclasts, and/or activating osteoblasts
A method for inhibiting the activation of macrophages, inhibiting the formation of osteoclasts, inhibiting the function of osteoclasts, and/or activating osteoblasts in a mammal is provided. The...
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8048861 |
Pesticidal formulations
The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic...
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8044030 |
Antibiotic macrocycle compounds and methods of manufacture and use thereof
The invention encompasses an active metabolite of the 18-membered macrocyclic antimicrobial agents, specifically, a metabolite of tiacumicin B and in certain embodiments, R-Tiacumicin B or and its...
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8017587 |
2-O- (β-D-glucopyranosyl) ascorbic acid, process for its production, and foods and cosmetics containing compositions comprising it
The present invention provides a novel ascorbic acid derivative as a provitamin C with improved stability in the body and prolonged life in the body compared to conventionally known...
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8003615 |
Stable vitamin B6 derivative
A compound represented by the following general formula (I) or a salt thereof: wherein R1 represents a glycosyl group, a phosphate group, or a cyclic phosphate group bound to R2; R2 represents...
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7998937 |
Flavonoid compound having an antiviral activity
The present invention relates to a flavonoid compound having an antiviral activity, more particularly to a flavonoid compound obtained by extracting Houttuynia cordata with methanol and...
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7999003 |
Antioxidant compositions and methods thereto
The present invention provides a performance assay that measures the total antioxidant activity of a composition using oxygen uptake in contrast to prior art methods that measure antioxidant...
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7994157 |
Method for dispersing plant sterol for beverage and a plant sterol-dispersed beverage, of which particle size is nanometer-scale in dispersed beverage
Disclosed are a method for dispersing plant sterol for beverage and a plant sterol-dispersed beverage, of which particle size is nanometer-scale in dispersed beverage. The dispersion of plant...
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7989424 |
Glucopyranosyloxypyrazole derivatives and use thereof in medicines
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug; one...
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7960352 |
Anti-cancer activity of Androsace umbellata Merr. extract and contained triterpene saponin
The present invention relates to an Androsace umbellata Merr. extract having anticancer activity and a triterpene saponin compound isolated therefrom, more particularly to an Androsace umbellata...
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7960353 |
Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders.
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7956040 |
Combination of catechin and quercetin for pharmaceutical or dietary use
The invention relates to a composition for pharmaceutical or dietary use that possesses antioxidant activity and characterized in that it contains as active principle a combination of catechin...
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7956041 |
Prophylactic and therapeutic agent of diabetes mellitus
The invention provides a prophylactic and therapeutic agent of diabetes mellitus, including a combination of an inhibitor of renal glucose reabsorption and a hypoglycemic agent. In accordance with...
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7943583 |
2-O-(β-D-glucopyranosyl) ascorbic acid, process for its production, and foods cosmetics containing compositions comprising it
The present invention provides a novel ascorbic acid derivative as a provitamin C with improved stability in the body and prolonged life in the body compared to conventionally known...
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7943584 |
Medicinal composition containing diabetes remedy
A pharmaceutical composition effective for the prophylaxis and treatment of diabetes is provided. This pharmaceutical composition comprises the combination of an α-amylase inhibitor selected from ...
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7935672 |
Derivatives of genkwanin and sakuranetin, cosmetic and therapeutic use thereof and preparation method of same
The invention relates to: (i) the use of osyl derivatives of genkwanin and sakuranetin having formula (I) in (a) cosmetics or dermatology and (b) therapeutics; (ii) the use of novel derivatives...
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7935673 |
Polyphenol glycoside isolated from acerola
It is an objective of the present invention to provide a polyphenol glycoside isolated from acerola, which has a binding mode that has not been conventionally known, and to provide the use of the...
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7915228 |
Derivatives of asimadoline with covalently bonded acids
The present invention relates to derivatives of N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)e
thyl]-2,2-diphenylacetamide with covalently bonded acids, and to the salts, solvates and...
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7910560 |
Method for increasing breast meat yield in poultry
A method for increasing breast meat yield in avians by treating the poultry with an effective amount of natamycin. The effective amount of natamycin can be added to the avian's feed wither directly...
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7910575 |
Prophylactic or therapeutic agents for allergic ophthalmic diseases or allergic nasal diseases, comprising tricyclic triazolobenzazepine derivative
The present invention provides a pharmaceutical composition for use in the prophylaxis or treatment of allergic ophthalmic diseases or allergic nasal diseases, which comprises...
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7875598 |
Compositions useful for the treatment of microbial infections
The present invention is based on the discovery that certain chemical compounds isolated from Chinese medicinal herbs are useful as anti-microbial agents, e.g., anti-bacterial agents, anti-fungal...
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7863248 |
Tyrosinase activity inhibitor and ameliorant for facial blood flow
A tyrosinase activity inhibitor and an ameliorant for facial blood flow that are excellent in terms of safety, and medicinal compositions, food compositions, and cosmetic preparations that contain...
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7863321 |
Anti-cancer combinations
The present invention relates to synergistic combinations of the compound 5, 6-dimethylxanthenone-4-acetic acid (DMXAA) and a compound selected from anthracyclines and topisomerase II inhibitors,...
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7854922 |
Skin preparation for external use characterized by containing sugar derivative of α, α-trehalose
The present invention has an object to provide an external dermatological formulation having satisfactory blood flow-promoting effect, antiinflammatory effect, antibacterial effect, moisturizing...
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7851477 |
Method for the treatment of skin
The present invention relates to a method for the treatment of skin redness by topically applying a composition containing caffeine to the affected skin. The invention method finds particular use...
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7838500 |
Crystalline form of 1′-(1-methylethyl)-4′-[(2-fluoro-4-methoxyphenyl)methyl]-5′-methyl-1H-pyrazol-3′-O-β-D-glucopyranoside, a method for its preparation and the use thereof for preparing medicaments
The invention relates to a crystalline form of 1′-(1-methylethyl)-4′-[(2-fluoro-4-methoxyphenyl)methyl]
-5′-methyl-1H-pyrazol-3′-O-β-D-glucopyranoside, to a method for the preparation thereof,...
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7829542 |
Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for...
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7820630 |
Substituted indole-O-glucosides
Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
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7816331 |
Substituted indazole-O-glucosides
Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
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7816330 |
Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides
This invention relates to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example,...
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7811998 |
Novobiocin analogues as anticancer agents
Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present...
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7807683 |
N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds,...
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7799763 |
Muscle-strengthening drugs and anti-inflammatory drugs
A muscle-strengthening, anti-inflammatory, antiasthmatic, antidiarrheal or an antidepressant method, or a method for the treatment of diminution of vision, hepatitis, inflammatory intestinal...
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7772195 |
Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia
A method for the treatment of obesity, diabetes, high cholesterol and related diseases including hyperglycemia, lipid disorders, hyperglyceridemia, dyslipidemia and atherosclerosis in mammals using...
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7772194 |
Pesticidal formulations
The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic...
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7763588 |
Method for increasing cognitive function and neurogenesis
The invention provides a method for improving cognitive performance in a physically active subject. The invention further provides a method of enhancing neurogenesis in a physically active subject....
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7759317 |
Analgesic and anti-inflammatory compositions and methods with flavonoid glycoside-type compounds
The present invention relates to pharmaceutical compositions containing certain flavonoid glycoside-type compounds that have been shown in the present invention to be therapeutically useful,...
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7749972 |
1-substituted-7-(β-D-glycopyranosyloxy)(aza)indole compound and pharmaceutical containing the same
The present invention provides a compound having an SGLT1 and/or SGLT2 inhibitory activity which is usable as an agent for the prevention or treatment of diabetes, postprandial hyperglycemia,...
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7737121 |
Insulin secretion by anthocyanins and anthocyanidins
A method for stimulating insulin secretion by anthocyanidins and anthocyanins is described. The secretion can be in vivo in mammals, including humans, or in vitro.
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7718694 |
Compositions and methods for therapy for diseases characterized by defective chloride transport
Compositions and methods for therapy of cystic fibrosis, asthma, and other conditions characterized by defective chloride transport are provided. The compositions comprise one or more compounds...
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7713569 |
Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof
The invention provides olive-derived hydroxytyrosol. According to one aspect of the invention, vegetation water is collected from olives. Acid is added to stabilize the vegetation water and prevent...
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7704961 |
Avermectins and avermectin monosacharides substituted in the 4′-and 4″ position having pesticidal properties
Described is a compound of the formula (I) wherein the bond between carbon atoms 22 and 23 is a single or double bond; m is 0 or 1; R1, is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; and either...
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