Matches 301 - 350 out of 383 < 1 2 3 4 5 6 7 8 >
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5017563 Castanospermine esters and glycosides  
Castanospermine mono- and di-esters and glycosides active as inhibitors of carbohydrate digestive enzymes and useful in treating diabetes are described herein. The compounds are prepared by the...
5011827 Elaiophyline derivatives, compositions containing them and the use thereof as anthelmintic agents  
The invention relates to elaiophyline derivatives of the formula I ##STR1## in which R 1 and R 1 ' are identical or different and represent a radical of the formula II/or III ##STR2## in which R 2...
5006340 Curable compositions for dental drugs having sustained release property  
A crude drug ingredient having bactericidal activity incorporated into a curable composition comprising a (meth)acrylate type monomer, a polymerization initiator and if necessary a filler to...
5003056 Antibiotic NK86-0279, process for production of the same and application of the same  
This invention relates to an antibiotic NK86-0279 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.
4997931 Epipodophyllotoxin glycosides  
The present invention relates to novel antitumor compounds which are 4'-demethylepipodophylloxtoxin derivatives. More particularly, the novel compounds are 4'-demethylepipodophyllotoxin...
4992423 Polycyclic ether antibiotics  
A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R 1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media...
4977143 Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR  
Antibacterial and antitumor agents designated LL-E333288ε-I and LL-E33288ε-Br and their production by strains of Micromonospora echinospora ssp. calichensis designated NRRL-15839, NRRL-15975 and...
4975278 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells  
This invention relates to a novel method for the delivery of cytotoxic drugs to tumor cells by the administration of a tumor-specific antibody-enzyme conjugate that binds to the tumor cells, and...
4960755 BU-3608 derivatives  
Disclosed herein are N-alkyl derivatives of antibiotics BU-3608, BU-3608 B, C, D and E as well as the corresponding desxylosyl compounds. These novel compounds are useful as antifungal agents.
4939123 Glycopeptide and oligosaccharide antibacterial compositions  
Adherence of pathogenic bacteria having type I fimbriae to animal cells is inhibited by compositions having active constituents which are new glycopeptide and/or oligosaccharide compounds. The...
4927638 Etoposide solutions  
A solution of etoposide in dimethylisosorbide is disclosed. The solution is useful for filling gelatin capsules and may also be formulated into parenteral dosage forms.
4920099 Aminoglycoside steroids, a process for their preparation, their use and pharmaceutical compositions containing them  
4888326 Method of treating defective T-lymphocyte function with rutin or troxerutin in combination with γ-linolenic acid or dihomo-γ-linolenic acid  
A pharmaceutical composition comprises one or more essential fatty acids, for example, γ-linolenic acid or dihomo-γ-linolenic acid, in conjunction with rutin, troxerutin or other bioflavonoid....
4861758 Coccidiocidal compositions  
Coccidiocidal compositions which contain the polyether antibiotic maduramicin or its salt in combination with one or more active substances from the group comprising meticlorpindol methyl...
4849409 Diels-alder adduct from streptazoline and naphthoquinones and its oxidation products, which have cytotoxic and antimicrobial activity and which act against protozoa  
Streptazoline is reacted with naphthoquinones in a Diels-Alder reaction, and the adduct is then oxidized. The resulting compounds have cytotoxic activity, in particular against leukemia cells, and...
4845090 Nitroxyl compound and diagnostic media based thereon useful for enhancing NMR imaging  
Diagnostic media suitable for NMR diagnoses contain compounds of Formula I ##STR1## wherein is a single bond or a double bond, X is the grouping --(CH 2 ) n -- or, if is a single bond, also...
4824829 Non-dusting antibiotic, anticoccidial premix compositions and a process for their manufacture  
The invention provides novel antibiotic, anticoccidial premix compositions which exhibit reduced dusting and lower dermal toxicities and a process for their manufacture.
4795742 Therapeutic composition from plant extracts  
Therapeutic compositions are composed of four plant extracts: ginsenoside, tetramethyl pyrazine, astragalan and atractylol. Pharmaceutical dosage units are prepared by conventional means with...
4780314 Isolation and purification of a digitalis-like factor  
This invention relates to a novel recovery process for obtaining the small molecular weight, digitalis-like factor, and further relates to purification of the digitalis-like factor. This invention...
4778785 Pharmaceutical composition for retarding and reducing cachexia  
A pharmaceutical composition for retarding and reducing cachexia comprising, as an efficacious ingredient, at least one compound selected from the group consisting of benzaldehyde and...
4774230 Glucuronic acid derivatives of opioid antagonists  
Intestine-specific delivery of an opioid antagonist can be accomplished without substantial central nervous system effects by administering the antagonist orally in the form of the glucuronide...
4772589 Etoposide solution in NMP  
A stable solution of etoposide in 1-methyl-2-pyrrolidinone is disclosed. The solution can be diluted with a parenteral vehicle to yield an infusion solution containing up to 10 mg/ml etoposide...
4753929 Flavone glycoside  
A flavone glycoside having the formula is isolated from the natural source and is found to be effective to amelioration of the hemolinetic disturbance. ##STR1##
4713246 Etoposide oral dosage form  
A liquid dosage form suitable for oral administration of etoposide which is sufficiently concentrated to be administered in capsule form and which provides improved absorption of the drug relative...
4707360 Vasculoprotecting pharmaceutical compositions  
Pharmaceutical compositions having vasculoprotecting activity, containing an ubiquinone compound together with one or more compounds of flavanoid, heparinoid, terpenic or glycosidic structure, such...
4705779 Pharmaceutical compositions of anti-pancreatic inflammatory effect  
The present invention relates to pharmaceutical compositions comprising 3-dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1 ,2,4-benzotria zine and at least one of a factor of Vitamine P...
4686206 Composition for activating function of phagocytes  
A pharmaceutical or veterinary composition for activating the function of phygocytes comprising as an effective ingredient a certain tocopheryl glycoside. The composition is useful for treating...
4617292 Pharmaceutical compositions and method for inhibiting histamine release tocopheryl glycoside  
A pharmaceutical composition for producing antiallergic activity containing as an active ingredient a certain tocopherol derivative having a sugar residue at 6-position of the...
4609644 Epipodophyllotoxinquinone glucoside derivatives, method of production and use  
Novel compounds having the structural formula: ##STR1## wherein R 1 is hydrogen and R 2 is alkyl, alkenyl, cycloalkyl, 2-furyl, 2-thienyl, aryl, aralkyl, aralkenyl, wherein the aromatic ring may...
4565862 Ethers of antibiotic X-14868A  
There is presented compounds of the formula ##STR1## wherein R is C 2 to C 7 alkyl or lower alkyl hydroxy and their pharmaceutically acceptable salts. The compounds exhibit activity as...
4560553 Use of eucalyptol for enhancing skin permeation of bio-affecting agents  
Eucalyptol is used to enhance skin permeation of bio-affecting agents.
4518589 BBM-2478 Antibiotic complex  
A novel antibiotic complex designated BBM-2478 is produced by fermentation of an actinomycete strain J907-21 (ATCC 39417). The complex may be separated chromatographically into two bioactive...
4515783 4-Amino-4-dehydroxy derivatives of efrotomycin and related compounds  
Compounds of the efrotomycin class having a 4-hydroxy-2-pyridone terminal group are converted into 4-amino-4-dehydroxy compounds. The amino group may be substituted with various substituents. The...
4511560 Antibiotic substances DC-45, and their use as medicaments  
New substances designated as DC-45-A, DC-45-B 1 and DC-45-B 2 and represented by the following general formula: ##STR1## wherein (i) R 1 and R 2 together with the carbon atom therebetween...
4510134 Controlling nematodes in animals and soil with nematocidal antibiotics  
There is provided a method for controlling nematodes in warm-blooded animals by orally administering thereto a nematocidally effective amount of a new antibiotic or mixture of antibiotics produced...
4496548 Composition and method for reducing hangover  
A novel composition and method is disclosed for preventing hangover effects in humans caused by consumption of alcoholic beverages. The composition comprises thiamine, ascorbic acid, at least one...
4496549 Treatment of malaria with antibiotics  
This invention relates to a novel method for the treatment of malarial infections in warm-blooded animals using the antibiotics X-14868A, LL-C23024 beta, LL-C23024 iota, and combinations theory and...
4493845 Antibiotic AM-3603  
Antibiotic AM-3603 which is also designated as irumamycin is represented by the following formula: ##STR1## This substance is active upon certain Gram-positive bacteria, phytopathogenic fungi and...
4459291 Compounds having antibiotic activity, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments  
New antibacterial compounds, DC--45--A 1 and DC--45--A 2 are produced by fermentation of a microorganism belonging to the genus Streptomyces. The antibiotics are accumulated in the culture liquor...
4452786 Condurango glycoside compounds, processes for their preparation, antitumor agents comprising them and compositions  
Novel condurango glycoside compounds, antitumor agents comprising them and processes for their preparation, compositions containing them and methods of treating tumor with them are disclosed herein...
4424212 K-41.C(2) esters  
This invention relates to K-41.C(2) esters, miticidal compositions comprising K-41.C(2) esters and anti-coccidial compositions comprising K-41.C(2) esters.
4406891 N-Methanesulfonic acid derivatives of istamycin A or B and production thereof  
As new semi-synthetic antibiotic derivative are provided N-methanesulfonic acid derivatives of istamycin A or B which are lower toxic than the parent antibiotic and retain usefully high...
4378433 Method for producing zinc etheromycin from fermentation broths  
Zinc complexes of glycolic monovalent monoglycoside polyether antibiotics are provided for use as coccidiostats and growth-promoting agents when administered to poultry and for use as active agents...
4375542 Kijanimicin antibiotics and derivatives thereof  
Actinomadura Kijaniata nov. sp produces a novel antibiotic which we have designated kijanimicin. The antibiotic or cationic salts thereof exhibit anti-acne, antitumor, antimalarial, antibacterial...
4363802 Moranoline derivatives  
Bisglucosyl moranoline of the formula (I) ##STR1## is useful in inhibiting increase of blood sugar in sugar-loaded animals and humans, and particularly for treatment of diabetes mellitus.
4342752 Carbalkoxymethyl derivatives of rutin poly(H-)sulfate and method of use  
Carbalkoxymethyl derivatives of rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.
4342753 Carboxyalkyl derivatives of rutin poly(H-)sulfate  
Carboxyalkyl derivatives of rutin polyl(H-)sulfate and salts thereof useful as complement inhibitors.
4329338 Compositions for use as cosmetics  
The invention relates to new compositions to be used as cosmetics. The new cosmetics according to the invention contain as active agent 0.06 to 10% by weight of a reaction product of nicotinic...
4302450 Polyether ionophores as antiobesity and hypotriglyceridemic agents  
A method is disclosed for the use of polyether ionophores as antiobesity and hypotriglyceridemic agents in warm blooded animals by the administration to an animal in need of such treatment of a...
4297348 Composition and method for the treatment of acne  
Therapeutic compositions for the treatment of acne which comprise from about 0.1% to about 5% by weight naringin, from about 0.1% to about 10% by weight naringenin, from about 0.05% to about 5% by...
Matches 301 - 350 out of 383 < 1 2 3 4 5 6 7 8 >