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6774130 |
Therapeutic compounds for inhibiting interleukin-12 signaling and methods for using same
Novel heterocyclic compounds having a six membered ring structure fused to a five membered ring structure are found to be useful for the treatment and prevention of symptoms or manifestations...
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6734187 |
Purine derivatives and medicaments comprising the same as active ingredient
Purine derivatives represented by the following formula and salts thereof: wherein R 1 represents a C 1 -C 4 alkyl group or difluoromethyl group; R 2 represents tetrahydrofuranyl group, a C 1...
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6642231 |
6,9-disubstituted 2-&lsqb trans-(4-aminocyclohexyl)amino&rsqb purines
The present invention comprises 6-9-Disubstituted 2-[trans-(4-aminocyclohexyl]aminopurines that are useful in inhibiting cyclin dependent kinases, particularly cdk-2. The present invention also...
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6025362 |
Uses of xanthine compounds
Xanthine compounds are utilized to accelerate anesthetic recovery from the effects of certain compounds as propofol, etomidate, barbiturates, opioids, isoflurane, enflurane, halothane, desflurane,...
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5872124 |
Treatment of diseases of the central nervous system using uric acid as a scavenger of peroxynitrite
The process of treating a disease of the central nervous system with an agent from one or more of the following three classes of agents: (1) nitric oxide scavengers, (2) peroxynitrite scavengers,...
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5753635 |
Purine derivatives and their use as anti-coagulants
This invention is directed to purine derivatives of the following formulae: ##STR1## wherein Z 1 is --O--, --N(R 10 )-- or --CH 2 O--; Z 2 is --O--, --N(R 10 )-- or --OCH 2 --; R 1 and R...
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5470858 |
Derivatives of (hetero)aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them
A compound represented by the following formula I: (HET)Ar--X--CH 2 --Y--CH 2 --O--R (I) wherein: (HET)Ar represents a bicyclic hetero aryl nucleus which is unsubstituted or...
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5409934 |
Xanthine derivatives
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4883801 |
Xanthine derivative pest control agents
The use of xanthine derivatives having the general formula: ##STR1## as pesticidal and pestistatic agents is disclosed, as well as pesticidal and pestistatic compositions containing same.
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4871742 |
Process and pharmaceutical compositions for the treatment of glaucoma
The invention relates to a process for the treatment of glaucoma comprising administering to a human in need thereof an effective amount of a compound selected from the inhibitors of xanthine-oxidase.
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4853373 |
Therapeutic treatment for arthritic condition
Hypoxanthine administered intradermally at a dosage range of 2×10 -8 to 1×10 -5 grams to a mammalian subject for the purpose of treating rheumatoid arthritis and osteoarthritis.
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4107306 |
Process for treating proliferative skin disease
A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc. comprising administering to humans, or domesticated animals, topically and/or systemically a...
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3608080 |
PROCESS FOR THE TREATMENT OF HYPERUREMIA OF NEPHRITIS
Process for the treatment of hyperuremia of nephritis comprising administering to a patient 2-30 grams per 24 hours of sarcosyluric acid.
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