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7538093 |
Compositions and methods for therapeutic use
A method and pharmaceutical composition for the enhancement of transfer of a therapeutic agent to a cell wherein the therapeutic agent is formulated in a buffer comprising a compound of Formula I: ...
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7534770 |
Glycoside having 4-methylergost-7-en-3-ol skeleton and hyperglycemia improving agent
3-O-β-D-Glucopyranosyl-4-methylergost-7-en-3-ol or a composition containing 0.001% by mass or more of the aforementioned compound, which is an extract of a plant of the family Liliaceae containing...
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7534769 |
Compositions and methods for enhancing delivery of therapeutic agents to cells
This invention provides methods and compositions for enhancing transfer of an agent into a cell. The agents can include polypeptides, polynucleotides such as genes and antisense nucleic acids, and...
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7534768 |
Treatment of DNA viral infections
The synergistic combination of a loop diuretic and a cardiac glycoside is useful in the treatment of DNA viral infections.
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7531520 |
Drug and food or drink for improving pancreatic functions
3-O-β-D-Glucopyranosyl-4-methyl-ergost-7-en-3-ol or a composition containing 0.001 to 10% by dry mass of the aforementioned compound, which is an extract of a plant of the family Liliaceae or a...
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7507720 |
5-Beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed.
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7402669 |
Method for preparing a Centella asiatica extract rich in madecassoside and in terminoloside
The invention concerns a method for preparing an extract comprising a mixture of madecassoside, terminoloside and optionally asiaticoside, an extract of Centella asiatica comprising more than 75...
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7387805 |
Flavonoid solubilizion agent and method of solubilizing flavonoid
A flavonoid solubilization agent capable of highly solubilizing flavonoids such as isoflavone, baicalin, rutin and naringin whose solubility is generally low; and a method of effecting the above...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7179455 |
Pesticide in gel form
The invention relates to a bait matrix which includes a gelling agent and a pesticide. The bait matrix is useful for controlling pests by attracting and poisoning them. The gel matrix is...
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7166611 |
Pharmaceutical compositions having appetite suppressant activity
A pharmaceutical composition contains an extract obtainable from a plant of the genus Trichocaulon or Hoodia containing an appetite suppressant agent having the formula (1). A process for...
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7163702 |
Process for isolating sea cucumber saponin Frondoside A, and immunomodulatory methods of use
This present invention discloses use of a chloroform/solvent mixture extraction at different solvent-to-feed ratios, followed by evaporation and extraction with ethyl acetate/water; followed by...
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7160866 |
Isolation of tigogenin pentaglycoside from Chlorophytum nimonii
The present invention provides a novel saponin tigogenin penta glycoside isolated from the aerial parts of Chlorophytum nimonii and a process for the isolation thereof as well as its use in...
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7153877 |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and...
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7119110 |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and...
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7115586 |
Non-inclusion cyclodextrin complexes
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization...
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7109175 |
Specific steady-state R-type CA2+ channel blockers and use thereof
The present invention relates to Ca 2+ channel blockers and more particularly to the R-type Ca 2+ channel blockers. More specifically, the invention relates to Ca 2+ channel blockers activity of...
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7101857 |
Crosslinkable biological material and medical uses
A method for promoting angiogenesis in a patient comprising providing crosslinkable biological solution to the target tissue, wherein the crosslinkable biological solution is loaded with at least...
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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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7091187 |
Compounds, compositions and methods for treatment of inflammatory diseases and conditions
The present invention relates (a) to new compounds represented by Formula I:
wherein M represents a macrolide subunit (macrolide moiety) derived from macrolide possessing the property of...
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7030094 |
Immunostimulant compositions comprising an aminoalkyl glucosaminide phosphate and QS-21
The invention provides pharmaceutical compositions, particularly vaccine compositions, employing an adjuvant system comprising RC-529 (an aminoalkyl glucosaminide phosphate compound) and QS-21 (a...
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7015202 |
Use of glycyrrhizin and its derivatives as MCP-1 production inhibitors
The object of the present invention is to provide the use of glycyrrhizin and its derivatives for inhibition of MCP-1 production. The present invention discloses an MCP-1 production inhibition...
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7008929 |
Sapogenin-based treatment
The present invention relates to the use of a sapogenin, chosen from diosgenin and hecogenin, and/or of a plant extract containing at least one of these sapogenins. A preferred use is the treatment...
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7001893 |
Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof
The present invention relates to an inclusion complex of Rifampicin and cyclodextrin (CD) that can be used as an anti-tubercular drug. The present invention also relates to a process for...
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6992068 |
Cytokine production inhibitors, agents for protecting and promoting liver function, anti-inflammatory agents, immunosuppressants, drugs, cosmetics, foods and food materials
Highly safe cytokine production inhibitors, agents for protecting and promoting liver function, anti-inflammatory agents and immunosuppressants. Brazilian licorice extract and periandrins, which...
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6930093 |
Use of ribofuranose derivatives against inflammatory bowel diseases
A method for the prophylaxis or treatment of an inflammatory bowel disease is provided, comprising administering to a patient having or at risk of developing an inflammatory bowel disease a...
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6916791 |
Androgen derivatives and uses thereof
Androgen glycosides provide free, circulatory androgen on oral administration as they are subject to less, first pass breakdown by the liver.
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6887853 |
Use of geldanamycin and related compounds for treatment of fibrogenic disorders
A method for prophylaxis or treatment of a mammal, particularly human, at risk for a fibrogenic disorder is disclosed. The compositions and methods of the invention are directed both to treatments...
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6867194 |
Enzyme activated nitric oxide donors
Sugar-modified SIN-1 compositions are provided. The compositions are useful for generating NO in response to hydrolytic activity of a glycosidase specific for the O-glycosidic bond between the...
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6861410 |
Immunological adjuvant compositions
The present invention is directed to novel adjuvant compositions, which target the cellular and/or humoral arms of immunity. According to an embodiment of the invention, an oil-in-water adjuvant...
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6844322 |
Method for induced lactation
Methods for effecting mammary secretion of milk from an animal, without the benefit of an immediately preceding pregnancy are provided. An exemplary embodiment the method comprises elevating an...
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6835715 |
Mammalian dihydroouabain-like factor and therapeutic compositions
A novel mammalian dihydroouabain-like factor is disclosed which substantially fails to cross-react with mammalian ouabain-like factor (OLF) for binding to anti-OLF antibody, but cross-reacts with...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6818624 |
Therapeutic agent for a cancer and method of screening the same, and health-care auxillary food
A therapeutic agent for a cancer comprising a therapeutically effective amount of an active ingredient, wherein the therapeutic agent is used referring to an ability of acting on NK cell antigen...
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6812214 |
Use of harpagid-related compounds for prevention and treatment of osteoporosis, arthritis and ruptured disc and pharmaceutical composition containing the same
In the present invention, it is discovered that a compound of formula (I) has a potent effect for treatment of osteoporosis, arthritis and ruptured disc: in which R 1 represents hydrogen atom...
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6812213 |
Steroidal sapogenins and their derivatives for treating alzheimer's disease
The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment,...
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6784160 |
Biologically active pregnene compounds
The subject invention provides novel compositions of biologically active glycosylated pregnene compounds which can advantageously be used for treating cancer and stopping cell proliferation.
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6784159 |
Triterpene saponins from soybeans for treating kidney disease
A method of treating polycystic kidney disease is described. The method involves administering soyasaponin B b to an animal in need thereof.
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6720307 |
Glycosylated analogs of fusidic acid
Novel analogs of fusidic acid are described with one or more carbohydrate units attached. Certain glycosylated analogs of fusidic acid have enhanced solubility properties in diluents or excipient...
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6713074 |
Cosmetic composition and method
The cosmetic topical formulation of this invention is directed toward diminishing skin wrinkling, fine line, improving skin tone, and combinations thereof. Preferably, the topical formulation...
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6699676 |
Uses of ouabain and ouabain-like molecules in apoptosis related pathologies
Longterm elevation of the intracellular Na + /K + ratio inhibits macromolecule synthesis and proliferation in the majority of cell types studied so far, including vascular smooth muscle cells...
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6670369 |
Use of phanquinone for the treatment of alzheimer's disease
The use of phanquinone for the manufacture of a pharmaceutical composition for the prevention or the treatment of Alzheimer's disease is disclosed. Also methods of treatment or prevention of...
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6670348 |
Methods and compositions for destruction of selected proteins
Compounds having an ansamycin anitibiotic, or other moiety which binds to hsp90, coupled to a targeting moiety which binds specifically to a protein, receptor or marker can provide effective...
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6664232 |
HLA-A2 restraint tumor antigen peptide originating in SART-1
An HLA-A2 restricted tumor antigen peptide originated fromr SART-1, derivatives thereof having characteristics functionally equivalent thereto; therapeutic, prophylactic or diagnostic agents for...
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6593301 |
Use of steroidal saponins for the prophylaxis or treatment of dementia, and novel steroidal saponin compounds
The invention relates to the steroidal saponin compounds for the propylaxis or treatment dementia, the new steroidal saponin compounds and the pharmaceutical composition containing the same.
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6579853 |
Brain cell or nerve cell-protective agents comprising ginsenoside Rb1
The present invention provides preparations for efficaciously administering ginsenoside Rb 1 or its salt useful as cytoprotective agents. More particularly, the present invention provides...
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6538027 |
Compositions comprising ratite oil or active fractions thereof and methods of using these composition as insect repellents
This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained...
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6528058 |
Saponin adjuvant composition
Art adjuvant composition for stimulating an effective immune resposne to an antigenic substance when co-administered to an animal with said antigenic substance, comprising: (a) a saponin with...
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6479063 |
Therapeutic uses of hormonal manipulation using combinations of various agents to treat atherosclerosis
A method of decreasing atherosclerosis and its complications involving administering to a human or animal various combinations of medications with Finasteride, Bicalutamide, Flutamide and Nilutamide.
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6419963 |
Composition and method for the treatment of diaper rash using natural products
Provided here is a pharmaceutical composition containing beeswax, olive oil, β-sitosterol and the herb Coptis chinesis Franch for safe and quick treatment for infant and adult diaper rash. Also...
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