Matches 201 - 250 out of 265 < 1 2 3 4 5 6 >
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4402948 Steroid glycoside compounds and methods of use  
Oxygenated sterylglycoside derivatives of the formula (I) wherein R 1 , R 2 , R 3 and R 4 are the same or different and each is hydrogen or lower alkanoyl, Y is ##STR1## and R 5 is...
4353895 Cardenolide-bis-digitoxoside alkyl compounds, pharmaceutical compositions and method of use  
Cardioactive cardenolide-bis-digitoxosides of the formula ##STR1## in which R 1 is a hydrogen atom, a hydroxyl group or an acyloxy radical containing up to 3 carbon atoms, and R 2 , R 3 and R...
4350688 Procedure for manufacturing saponine extract  
A saponine extract product which is a granulate in pellet form, the granules being pourable and having low hygroscopicity. A process for producing a pourable granular saponine extract product of...
4339442 Gynosaponins, their use and a process for preparing the same  
There disclose a group of new saponins designated as gynosaponins which have been isolated from a plant of Gynostemma pentaphyllum Makino of Cucurbitaceae, pharmaceutical use thereof and a method...
4335113 Triterpenic saponin having pharmacological potency  
The present invention concerns a new triterpenic saponin derived from caulophyllogenin, the process for extracting it from varieties of Chrysanthellum, and its therapeutic use. This saponin is...
4333926 Steryl-β-D-glucoside pharmaceutical compositions and use  
Hemostatics, vascular stabilizers and anti-shock compositions containing at least one steryl-β-D-glucoside or monopalmitates thereof, of the formula: ##STR1## in which R 1 is β-sitosteryl,...
4330534 N.sup.4 -Acylcytosine arabinoside compositions  
A N 4 -acylcytosine arabinoside preparation which consists essentially of (a) a liposome of lecithin and (b) a N 4 -acylcytosine arabinoside having a C 6 -18 aliphatic acyl group and being...
4320119 Extracts of Marsdenia cundurango Reichenbach fil  
New extracts of Marsdenia cundurango Reichenbach fil., processes for preparing them, antitumor agents comprising them, compositions containing them and methods of treating tumor with them are...
4320120 Extracts of Marsdenia cundurango Reichenbach fil  
New extracts of Marsdenia cundurango Reichenbach fil., processes for preparing them, antitumor agents comprising them, compositions containing them and methods of treating tumor with them are...
4317816 Saponin containing composition effective against adrenal atrophy  
This invention is directed to a pharmaceutical composition containing saponin and a method of using the saponin containing composition for preventing and treating adrenal atrophy and other organ...
4301152 Immunologic adjuvant  
Immunologic adjuvants are obtained by the synthesis of 6-(5-cholesten-3β-yloxy)hexyl 6-amino-6-deoxy-1-thio-β-D-galactopyranoside and its 6-deoxy-6-oleamido derivative.
4292314 Cardioactive 12-dehydrodigoxin-oximes  
The present invention provides 12-dehydrodigoxin oximes of the general formula: ##STR1## wherein R 1 and R 2 , which can be the same or different, are hydrogen atoms, lower acyl radicals or lower...
4283394 Cytotoxic nucleoside-corticosteroid phosphodiesters  
Nucleotides of nucleosides or bases having known cytotoxic activity are reacted with steroids, preferably corticosteroids, to form corresponding cytotoxic nucleoside-corticosteroid phosphodiester...
4265886 Spiroketalins and their applications  
The present invention provides a pharmaceutical composition, primarily for the treatment of inflammatory conditions, including benign prostata hypertrophy, the composition containing a spiroketalin...
4260603 Sterol glycoside with activity as prostaglandin synthetase inhibitor  
Medicaments are prepared having activity as prostaglandin synthetase inhibitor comprising certain sterol glycosides, a fatty acid ester thereof or a spiroketal-steroid glucoside or fatty acid ester...
4254111 Sterolin products  
The invention is concerned with new chemical compounds being the hemiesters of steryl glycosides, methods of preparing these hemiesters, and pharmaceutically, particularly anti-inflammatory,...
4242332 4,5-Methano-bufadienolide-rhamnosides, their preparation, and drugs containing these compounds  
4,5-methano-bufadienolide-rhamnosides of the formula I ##STR1## where R 1 is hydrogen or alkyl or acyl of 1 to 4 carbon atoms, R 2 and R 3 are identical or different and each is hydrogen or...
4198391 Pharmaceutical compositions  
A cardiotonic dosage unit form comprises a soft gelatin capsule containing a liquid cardiotonic composition comprising (a) a cardiac glycoside, preferably digitoxin or digoxin; (b) ethanol; (c)...
4188379 Sterolins and their use  
Sterol glycosides and esters thereof with monocarboxylic acids of natural or synthetic origin are used to combat human and animal illness in dosages of not over 10 mg per day.
4166849 Peruvoside derivatives and processes for their preparation  
The present invention is directed to novel peruvoside derivatives having the formula ##STR1## and the formula ##STR2## wherein R 1 and R 2 are the same or different and are selected from a...
4147768 Enteric coated digoxin and therapeutic use thereof  
Therapeutic and undegraded levels of digoxin in warm-blooded animals are achieved by orally admininstering thereto, a non-toxic pharmaceutical enteric-coated tablet comprising: (a) A cardiotonic...
4129649 Process for producing easily absorbable amorphous steryl glucoside monopalmitates and preparations thereof  
A process for producing amorphous preparations of steryl glucoside monopalmitates, wherein steryl glucoside monopalmitates are heated at a temperature above 110° C up to about 145° C or the...
4107299 Cardioactive 12-epi-digoxin and derivatives thereof  
12-Epi-digoxins of the formula ##STR1## wherein R 1 and R 2 each independently is hydrogen or a lower alkanoyl or alkyl radical, R 3 is hydrogen or a lower alkanoyl radical, and R 4 is...
4107306 Process for treating proliferative skin disease  
A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc. comprising administering to humans, or domesticated animals, topically and/or systemically a...
4101652 Pharmaceutically active complexes and pharmaceutical compositions containing eascin and sterols  
Complexes of saponins with sterols are disclosed which possess the pharmaceutical activity of the free saponins, but which have reduced side-effects. Also disclosed are pharmaceutical compositions...
4088757 4'Alpha- and 4'beta-amino-4'-desoxyoleandrins, and pharmaceutical composition containing same  
The present invention relates to 4' amino-4' desoxy-oleandrins of the following formula (I) ##STR1## in which R 1 and R 2 may be the same or different and represent hydrogen or a lower alkyl...
4088750 Method and preparation for increasing bioavailability of digoxin  
Method and preparation for increasing the bioavailability of digoxin to treat cardiac insufficiency in a human, said method comprising the administration of a preparation comprising a capsule...
4083969 Process for preparing easily absorbable sterol glycoside  
Sterol glycosides are rendered easily absorbable through the digestive tract by dissolving or dispersing the steroid glycoside with heating into a water solution of a polymer or polymers and then...
4067960 Pharmaceutical compositions containing cardiac glycoside  
A cardiotonic dosage unit form comprises a soft gelatine capsule containing a liquid cardiotonic composition comprising (a) a cardiac glycoside, preferably digitoxin or digoxin; (b) dimethyl...
4038386 Derivative of desglucohellebrin and therapeutic use  
Compounds are prepared of the formula ##STR1## The compounds of the invention possess valuable pharmacodynamic properties. They especially have a positive inotropic effect which is particularly...
4031212 3β-(4-Oxo-.a lpha.-L-rhamnosyl)-β-hydroxy-bufa-4,20,22-trienolide  
The compound of the formula ##STR1## which is useful as a cardiotonic.
4021535 Reagents used in the radioimmunoassay of digoxin  
The derivatives of digoxin useful in the radioimmunoassay of digoxin having the following formulae: ##STR1## where R is a carboxylic acid ester. These derivatives are formed by the following...
4021547 3β-(α-L-althromethylosyl)-14β-hydroxy-bufa-4,20,22-trieno lide and acylated derivatives thereof  
Compounds of the formula ##STR1## wherein R 1 , R 2 and R 3 are hydrogen or carboxylic acyl, particularly acetyl, benzoyl or p-nitro-benzoyl; the compounds are useful as cardiotonics.
4021546 Pro-drug forms of digoxin and method of preparing and using same  
There is provided, a novel pro-drug form of digoxin having the following formula: ##STR1## wherein R represents a member selected from the group consisting of a hydrogen atom, a residue of any...
4020159 Methods of and medications for treating cardiac disorders by using strophanthin  
Methods of treating cardiac disorders by the oral administration of a g- or k-strophanthin, and medications for use in such methods.
4003997 Heart glycosides and process for preparing them  
Cyclic 2',3'-ethers of 3-hydroxy-14,15β-oxido-14β-bufa-4,20,22-trienolide, 3β-(α-L-rhamnopyranoside) and process for preparing them. The compounds have a strongly positive inotropic activity...
4003998 α-Acyl derivatives of digitoxin  
Compounds of the formula ##STR1## wherein R 1 is ##STR2## R 2 is alkyl of 2 to 15 carbon atoms; mono-substituted alkyl of 1 to 4 carbon atoms, the substituent being halogen, cyano, carbethoxy,...
4002718 Gelatin-encapsulated digoxin solutions and method of preparing the same  
Digoxin solutions are disclosed which are compatible with gelatin and which are of relatively high concentration, thereby permitting encapsulation of therapeutic amounts of digoxin in soft gelatin...
4001402 Cardenolide glycosides and method of making the same, and therapeutic composition  
Cardioactive glycosides of the formula ##STR1## are disclosed, wherein R 1 is saturated aliphatic hydrocarbon having 1 - 4 carbon atoms or unsaturated aliphatic hydrocarbon having 2 - 4 carbon...
3991186 Steryl-β-D-glucoside ester pharmaceutical compositions and method of use  
Steryl-6-O-palnitoyl and -2,3,4,6-O-tetrapalmitoyl-β-D-glucosides are anti-inflammatory agents. The compounds, of which β-sitosteryl-2,3,4,6-O-tetrapalmitoyl-β-D-glucoside is a representative...
3981992 Derivatives of 3β-(4'-oxo-α-L-rhamnosyl)-14β-hydroxy-bufa-4,20,22-trien olide  
Compounds of the formula ##SPC1## Wherein R is ##SPC2## R 1 is hydrogen or alkoxy of 1 to 4 carbon atoms, and R 2 is alkoxy of 1 to 4 carbon atoms, or R 1 and R 2 together are...
3966918 Method of preparing aqueous solutions of sterol glycosides and their ester derivatives  
A method of preparing aqueous solutions of sterol glycosides and their ester derivatives characterized by solubilizing sterol glycosides and their ester derivatives by (1) dissolving said sterol...
3949074 Cardiotonic pharmaceutical compositions containing a cardiac glycoside and method of use  
Pharmaceutical compositions containing as an active ingredient a compound of the formula ##SPC1## Wherein R is cyano or carbalkoxy of 2 to 4 carbon atoms; and a method of using the same as...
3932626 Pharmaceutical compositions containing a carboxylic acyl derivative of digoxin and method of use  
Pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula ##SPC1## Wherein R 1 is alkyl of 2 to 12 carbon atoms, halo-(alkyl of 1 to 4 carbon atoms),...
3929996 Pharmaceutical compositions containing a digoxin complex  
Digoxin forms novel complexes with dihydroxybenzenes such as hydroquinone, resorcinol and pyrocatechol. These complexes exhibit rapid dissolution and high solubility in aqueous media. The...
3898331 4'-Dehydro-oleandrin and pharmaceutical composition thereof  
A new compound is disclosed which is named 4'-dehydro-oleandrin. It has the structure ##SPC1## And is useful as a cardiotonic.
3856944 PHARMACEUTICAL COMPOSITIONS  
Method for selective partial hydrolysis of steroid glycosides of 2-deoxysugar units, which comprises reacting glycol cleaving agents followed by optional reduction and mild hydrolysis, cardiotonic...
3471614 HELVETICOSIDE DERIVATIVES  
3462528 DIETHERS OF HELVETICOSIDE AND HELVETICOSOL  
3458628 ACOVENOSIDE DERIVATIVES  
Matches 201 - 250 out of 265 < 1 2 3 4 5 6 >