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4269836 |
4H-Pyrazolo[4',3':5,6]pyri do[4,3-d][1,2,4]triazolo[3,2-b]-pyrimidin-5(8H)one and derivatives thereof
New 4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyr
imidin-5(8H)on e and new derivatives thereof have the general formula ##STR1## The compounds are useful as anti-inflammatory agents...
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4233300 |
8H-Pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidine
New derivatives of 8H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidine
have the general formula ##STR1## The compounds are useful as anti-inflammatory agents and central nervous system...
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4167569 |
Pyrimido[1,2-a ]benzimidazole derivatives
The invention concerns 3,4-dihydropyrimido [1,2-a]benzimidazole derivatives bearing one or more substituents at positions 6, 7, 8 or 9; processes for their preparation and manufacture; and...
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4141979 |
Tetrazolo[a]quinazol-5-ones antiallergy and antiulcer agents
A series of tetrazolo[a]quinazol-5-ones, methods for their production and use as antiallergy agents and antiulcer agents.
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4134981 |
Pyrimidal [2,3,d]Pyrimidin-4(3H)-ones as antiallergy agents
Fused heterocyclic ring systems in which a quinoline or a pyridine component is "fused" to a pyrimidine having a 2-methyl, 2-ethyl, or 2-acetyl group and a 4-keto group, and to similar ring systems...
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4128645 |
4H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)one and derivatives thereof
New 4H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-
5(8H)one and new derivatives thereof have the general formula ##STR1## The compounds are useful as anti-inflammatory agents and...
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4127655 |
8H-Pyrazolo[4',3':5,6]pyrido[3,4-e] [1,2,4]triazolo-[1,5-a]pyrimidines
New derivatives of 8H-pyrazolo[4',3':5,6]pyrido[3,4-e]-[1,2,4]triazolo[1,5-a]py
rimidine have the general formula ##STR1## The compounds are useful as anti-inflammatory agents and central nervous...
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4083980 |
Derivatives of quinazolone
Compounds of the formula ##STR1## wherein A is --CHCH--, --CHN-- or --S--, R 1 is hydrogen, lower alkyl, lower alkoxy, amino, acetylamino, cyano, tetrazol-5-yl, --COR 3 or a fused...
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4070466 |
4H-pyrazolo[1 ,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)one and derivatives thereof
New 4H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido-[3,4-e]pyrimidin
-5(8H)one and new derivatives thereof have the general formula ##STR1## The compounds are useful as anti-inflammatory agents and...
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4066766 |
1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents
A novel series of 1-oxo-1H-6-substitutedpyrimido[1,2-a]quinoline-2-carboxylic acids of the formula ##STR1## wherein each of R 1 , R 2 and R 3 is hydrogen, alkyl having from 1 to 5 carbon atoms,...
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4029793 |
Synergistic local anesthetic compositions
A local anesthetic composition comprising a mixture in a pharmaceutically acceptable carrier of a particular toxin, namely, tetrodotoxin or desoxytetrodotoxin, and another compound, generally a...
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4011323 |
Bi-4-[1-(quinazolinyl-4)piperidyls] and bis{4-[1-(quinazolinyl-4)piperidyl]alkanes}
Disclosed are bi-4-[1-(quinazolinyl-4)piperidyls] and bis{4-[1-(quinazolinyl-4)piperidyl]alkanes}, e.g. 1,3-bis{4-[1-(6,7-dimethylquinazolinyl-4)piperidyl]propane},
having pharmacological activity...
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4000277 |
3,11-Dihydro- 6H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-6-one and derivatives thereof
New 3,11-dihydro-6H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]-pyrido[4,
3-d]pyrimidin- 6-one and new derivatives thereof have the general formula ##STR1## The compounds are useful as anti-inflammatory...
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4000275 |
Immunosuppressants
Benzimidazo[2,1-b]quinazolin-12(6H)ones, immunosuppressives and agents for treatment of auto-immune diseases, are prepared via (1) reacting a 2-chlorobenzimidazole with an anthranilic acid or...
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3987160 |
Pharmaceutical compositions comprising azapurinones useful in treating allergic respiratory disorders
8-Azapurin-6-ones substituted in the 2-position by an unsubstituted or substituted phenyl or naphthyl group, or by an alkenyl or alkynyl group, a cycloalkyl group, an alkyl group contaning 2 to 10...
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3694551 |
HYPOGLYCEMIC COMPOSITIONS AND METHODS FOR 1-PHENYLSULFONYL-2-IMINO-IMIDAZOLIDINES AND HEXAHYDROPYRIDINES
1-Phenylsulfonyl-2-imino-imidazolidines and -hexahydropyrimidines, substituted at the heterocyclic ring and substituted or unsubstituted at the phenylring are prepared; these compounds and their...
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