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9040488 Imino sugar derivatives demonstrate potent antiviral activity and reduced toxicity  
Imino sugars, such as deoxynojirimycin (DNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II (enzymes that process N-linked glycans in glycoprotein) and exhibit...
9040503 Medicinal carbohydrates for treatment of respiratory conditions  
A method of promoting recovery of cell viability of a damaged respiratory cell. The method includes a step of administering to the cell at least one pharmaceutically acceptable compound, which...
9034833 Anti-aging composition containing high levels of a jasmonic acid derivative  
A water-releasing anti-aging composition in the form of an emulsion and process for preparing the anti-aging composition are provided. The anti-aging composition includes an aqueous phase and an...
9034834 Antiviral supplement formulations  
The disclosure provides an oral antiviral supplement composition comprising a lysine, an ascorbic compound, a flavonoid glycoside, a threonine, and a pyridoxine. The disclosure also provides a...
9023816 Bioactive alkaloid compositions and their medical uses  
The present invention relates to a novel alkaloid and novel bioactive alkaloid fractions derivable from Ribes preferably selected among Ribes Rubrum and Ribes nigrum; methods of manufacturing such...
9023813 Synthesis and use of glycoside derivatives of propofol  
The present invention relates to methods and compositions for the synthesis, production, and use of pro-drug propofol analogs. This invention relates to a method for the production of a broad...
9023763 Modification of trehalose-6-phosphate levels in plants  
Compounds which are trehalose-6-phosphate or trehalose-6-phosphonate precursors of formula (I) or agriculturally acceptable salts thereof are provided: (I) The compounds are useful in increasing...
9023812 Neuroprotective ganglioside compositions for use in treating huntington's disease  
Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of a polyglutamine stretch in the protein huntingtin (Htt). HD neurons are dysfunctional at multiple levels and...
9023814 Glycomimetic compounds as anti-infectious against pathogens lectins  
The present invention relates to a calixarene-based glycosylated compound (I) having the formula: (I) wherein D is independently selected in the group comprising a —CH2-group, an oxygen atom, a...
9023815 Method for treating rhinitis and sinusitis by rhamnolipids  
The present invention is directed to methods for treating rhinitis or sinusitis in a subject. In one embodiment, the method comprises the steps of: identifying a subject in need thereof, and...
9012415 Photo-crosslinked gellan gum-based hydrogels: preparation methods and uses thereof  
This invention refers to photo-crosslinked hydrogel materials based in gellan gum suitable for tissue engineering and regenerative medicine applications or as drug delivery systems. Formulations...
9012410 Method of treating intrauterine inflammation  
A method of treating intrauterine inflammation in a subject associated with intrauterine bacterial infection includes administering to the subject a therapeutically effective amount of a toll-like...
9012413 FGF receptor-activating N-acyl octasaccharides, preparation thereof, and therapeutic use thereof  
The invention relates to FGF receptor-activating N-acyl octasaccharides having Formula (I), wherein: R1 is an O-alkyl group optionally replaced by one or more aryl or cycloalkyl groups, R2 is an...
9006211 Hypersulfated disaccharide formulations  
Hypersulfated disaccharides with utility in asthma or asthma related disorders are disclosed. The compounds are formulated with agents that enhance the oral delivery of the hypersulfated...
8993539 Dietary fiber supplements for appetite suppression  
The present invention provides a composition of dietary fiber supplements for satiety enhancement and appetite suppression in treatment of overweight, obesity, or eating disorders. The composition...
8987216 Polysulfated glycosides and salts thereof  
The invention relates to polysulfated glycosides of formula (I), the pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions containing these compounds as active...
8980846 Composition containing styraxlignolide A or the aglycone thereof as an active ingredient for preventing or treating asthma  
The present invention relates to a pharmaceutical composition for preventing or treating asthma, the composition containing styraxlignolide A or an aglycone thereof as an active ingredient. More...
8975235 Lysophosphatidic acid receptor antagonists  
Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases,...
8975234 Anti-bacterial infection, inflammation, and leukemia composition and use thereof  
A method of inhibiting the growth of Gram-positive bacteria comprising administering an effective amount of Tellimagrandin II, its pharmaceutically acceptable salt, enantiomer, isomer or tautomer...
8975299 Lipid mixture for infant nutrition  
The subject invention thus provides a composition comprising at least one triglyceride, at least one phospholipid and at least one poly-unsaturated fatty acids (LC-PUFA); wherein at least about 1%...
8975233 Methods for renal denervation  
Various agents are described to denerve, modulate, or otherwise affect the renal nerves and other neural tissue. Also, various delivery devices are described to deliver an agent locally to the...
8962573 Compounds targeting the cation-independent mannose 6-phosphate receptor  
The invention relates to conjugates of products of interest including glycoproteins, nanoparticles, and imaging agents and of compounds of the general formula (1): that target the...
8962578 Fungicidal active substance combinations  
The invention relates to novel fungicidally active compound combinations of 2′-cyano-3,4-dichloroisothiazole-5-carboxanilide and active compounds listed in the disclosure.
8951976 Progression inhibitor for disease attributed to abnormal accumulation of liver fat  
The present invention provides pharmaceutical compositions useful as agents for the inhibition of progression of diseases associated with abnormal accumulation of liver lipids. In particular, the...
8940314 Repellent to insects harmful to a plant and method for repelling the same  
The invention provides a repellent to harmful flying insects which comprises as an effective ingredient at least one selected from the group consisting of glycerin fatty acid ester, sorbitan fatty...
8932594 Adjuvants and methods of use  
Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune response are also disclosed....
8927506 Acetates of 2-deoxy monosaccharides with anticancer activity  
Novel compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are provided herein.
8906891 Na/K-ATPase ligand  
This process relates to a pharmaceutical composition of an Na—K-ATPase ligand which will stimulate Na/K-ATPase signaling in a pharmaceutically acceptable vehicle. In one embodiment, the...
8895516 Modified saccharides, conjugates thereof, and their manufacture  
Saccharide-protein conjugates having a new type of linker are described. The conjugates comprising the new linker are prepared from modified saccharides comprising a moiety of the formula (I):...
8889191 Sustained-release formulations of topiramate  
Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the...
8883746 α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation method and pharmaceutical composition for the immune adjuvant containing the same as an active ingredient  
Disclosed are novel α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation methods thereof, and pharmaceutical compositions for use in an immune adjuvant...
8883743 Methods for treating obesity employing an SGLT2 inhibitor  
Methods are provided for treating obesity or causing weight loss in a mammalian subject or patient, wherein a therapeutically effective amount of an SGLT2 inhibitor alone or optionally in...
8883745 C—glycolipids with enhanced Th-1 profile  
The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells....
8877248 Sustained-release formulations of topiramate  
Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the...
8877684 Pesticidal composition comprising a synthetic compound useful as nodulation agent of leguminous plants and an insecticide compound  
A composition comprising at least a compound (a) of general formula (I): and an insecticide compound (b) in a (a)/(b) weight ratio of from 1/1 to 1/1013. A composition further comprising an...
8877718 Antiinfective and antitumoral compounds isolated from tropical lianas  
The present invention relates to naphthoquinone derivatives isolated from solid callus cultures from two species of the palaeotropical plant families Dioncophyllaceae and Ancistrocladaceae. It...
8865661 Method of lowering glycemic index of foods  
A method of delaying digestion by an animal or a human of carbohydrates in food, comprising administering an effective amount of one or more flavonoids to the animal or human in conjunction with...
8865664 Hydrophobically enhanced aminoglycosides  
Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections....
8865660 Method of treating neurogenic overactive bladder in a mammal or method of treating non-psychological stress-related bladder dysfunction in a female mammal by administering at least on jasmonate  
A formulation or composition contractility comprising jasmonate for modulating bladder and/or treating bladder dysfunction, particularly an overactive bladder in a mammal, particularly a human and...
8859508 Application of 5-methyl-1,3-benzenediol or derivatives thereof in the preparation of medicines and functional foods for treatment or prevention of depression  
The present invention relates to the application of 5-methyl-1,3-benzenediol or its derivatives represented by Formula I; wherein the constituent variables are as defined herein or pharmaceutical...
8859612 Use of hesperidin or one of its derivatives for making a medicine for bone formation stimulation  
The invention relates to the use of the compound hesperidin or of one of its derivatives for the manufacture of a composition designed to stimulate bone formation and/or inhibit bone resorption in...
8859509 Chimeric small molecules for the recruitment of antibodies to cancer cells  
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The...
8852630 Chimeric small molecules for the recruitment of antibodies to cancer cells  
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The...
8853173 Synthetic glycolipid and use thereof  
A compound represented by the following formula (1): wherein R1 is an aldopyranose residue wherein the 6-hydroxyl group is optionally alkylated, R2 is a C1-26 hydrocarbon group optionally having...
8853172 Anti-plant-virus agent  
The present invention provides an anti-plant virus agent which exhibits preventative and therapeutic effects on plant virus diseases. The anti-plant virus agent of the present invention is...
8841261 Functional powdery product  
The present invention has objects to provide a functional powdery product prepared by allowing carriers to support one or more members selected from vitamin glycosides, and to provide external...
8841322 Method for increasing the activity of lysosomal enzymes  
Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance...
8834852 Composition for oral cavity  
The present invention relates to an oral care composition, which contains a compound represented by the formula (A): (wherein, R represents a substituted or unsubstituted, linear or branched alkyl...
8828952 Sulfated oligosaccharide derivatives  
The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions...
8828955 Glutathione production enhancer, prophylactic/therapeutic agent for diseases caused by glutathione deficiency, and food, beverage and feed  
The invention aims at finding a highly-safe natural product having glutathione production-enhancing activity, and providing a glutathione production enhancer and a prophylactic/therapeutic agent...