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8183214 Cell surface coating with hyaluronic acid oligomer derivative  
Method of localizing hyaluronic acid to the surface of a cell or multi-cellular structure by contacting the cell or multi-cellular structure with a dispersion of a construct of the structure...
8183215 Method of administering oral flora-improving agent, antibacterial agent and growth promoter  
It is intended to provide an oral flora-improving agent capable of forming a favorable flora in the oral cavity and a food or a drink for improving the oral flora. An oral flora-improving agent...
8183213 Combination therapy comprising glucose reabsorption inhibitors and retinoid-X receptor modulators  
Combination therapy comprising RXR modulators and glucose reabsorption inhibitors useful for the treatment of diabetes and Syndrome X are disclosed.
8178500 Pesticidal compositions  
Stabilized mixtures of pesticides are disclosed.
8178512 Methods and compositions for treating diseases and disorders associated with siglec-8.  
The invention provides therapeutic methods and compositions for the prevention and treatment of Siglec-8 associated diseases and disorders such as asthma and allergic reactions. In particular, the...
8178663 Ester derivatives of hyaluronic acid for the preparation of hydrogel materials by photocuring  
The present invention relates to hyaluronic acid ester derivatives, whose carboxylic groups are partially esterified with hydroxy groups of propiophenone derivatives, to the hydrogel materials...
8178499 Ester derivatives of hyaluronic acid for the preparation of hydrogel materials by photocuring  
The present invention relates to hyaluronic acid ester derivatives, whose carboxylic groups are partially esterified with hydroxy groups of propiophenone derivatives, to the hydrogel materials...
8173608 Compound having cyclic structure and use thereof  
The present invention relates to a compound represented by the following formula (1′) wherein R is an aldopyranose residue, R2 is a C2-18 hydrocarbon group optionally having substituent(s), R3 is a...
8173610 Derivatives of epirubicin, their medicinal application and pharmaceuticaly acceptable forms of drugs  
The present invention relates to novel derivatives of epirubicin, pharmaceutical composition comprising these derivatives, and uses of epirubicin and its derivative for treating HCV.
8173607 Promoter for the production of hyaluronic acid containing ginsenoside compound K  
There are provided a promoter containing ginsenoside compound K for the production of hyaluronic acid, and more particularly, a new efficacy of 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol ...
8173606 Sulfated oligosaccharide derivatives  
The invention relates to compounds which are polysulfated oligosaccharide derivatives having activity as inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase;...
8168159 Compounds for tumor diagnosis and therapy  
The present invention discloses a method for the enzyme-mediated, site-specific, in-vivo precipitation of a water soluble molecule in an animal. The enzyme is either unique to tumor cells, or is...
8168220 Dosage forms of active ingredients containing hydroxystilbene for treating menopausal complaints  
The invention relates to novel dosage forms containing hydroxystilbene, to a method for producing said dosage forms and to their use for treating female menopausal complaints, juvenile...
8168598 Optimised formulation of tobramycin for aerosolization  
The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room...
8168595 Antithrombotic dual inhibitors comprising a biotin residue  
The present invention relates to compounds of the formula (I) oligosaccharide-spacer-A (1), wherein the oligosaccharide is a negatively charged oligosaccharide residue comprising two to twenty five...
8163705 Glycolipid and use thereof  
The present invention provide a compound represented by the following formula (1) wherein each symbol is as defined in the specification, or a salt thereof. The compound of the present invention...
8148335 De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy  
The present invention generally provides compositions methods and composition relating to the diagnosis and/or treatment of cancers having a cell surface de-N-acetylated sialic acid antigen, e.g.,...
8128948 Compositions and methods for attracting Anastrepha species  
A composition containing suspensolide and optionally at least one of γ-hydroxy acid of epianastrephin, γ-hydroxy acid of anastrephin, 2,6-dimethyl-6-vinyl-cyclohexeneacetic acid, β...
8129350 Method of lowering Glycaemic Index of foods  
A method of delaying digestion by an animal or a human of carbohydrates in food, comprising administering an effective amount of one or more flavonoids to the animal or human in conjunction with...
8124115 Alcoholic pump foam  
An alcoholic foam composition, which can be dispensed as a foam via a pump-foam system contains a) at least 52 to ≦99 wt % of an alcohol or mixture of alcohols, b) a surfactant or a surfactant m...
8124575 Polymeric surfactants based upon alkyl polyglycosides and sugars  
The present invention relates to a series of polyglycoside derivatives that are (a) polymeric (that is cross linked with hydroxypropyl linkages) and (b) contain additional functional groups...
8106007 Conjugates of a polypeptide and a pentasaccharide  
The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being...
8106022 Carbohydrate conjugates as delivery agents for oligonucleotides  
The present invention provides iRNA agents comprising at least one subunit of the formula (I): wherein:A and B are each independently for each occurrence O, N(RN) or S;X and Y are each...
8097593 Lipid A and other carbohydrate ligand analogs  
The core structure of pentaerythritol has been used as a replacement for one or both sugars in lipid A, leading to the generation of a series of lipid A analogs. These lipid A analogs may further...
8092780 Polyvalent conjugate vaccine for cancer  
This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated...
8093227 Monosaccharide compounds and methods therefor  
A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds...
8088743 Methods for treating obesity employing an SGLT2 inhibitor  
Methods are provided for treating obesity or causing weight loss in a mammalian subject or patient, wherein a therapeutically effective amount of an SGLT2 inhibitor alone or optionally in...
8080527 Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection  
The invention provides compositions and methods for reducing one or more symptoms of an autoimmune disease, inflammatory disease, and/or transplant rejection, by the administration to a subject in...
8080539 Method of treating human preeclampsia employing resibufagenin  
A method of treating preeclampsia including administering a therapeutically effective dose of resibufagenin to a patient having preeclampsia. Effecting the determination of the presence of...
8071558 Application of D-psicose to suppression of abnormal circadian increase in blood glucose level  
A novel use of D-psicose (for suppressing the abnormal intra-day increase of blood glucose level) is provided. A composition containing D-psicose as the active component and for use in suppressing...
8058245 Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof  
The present invention provides fused heterocyclic derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an...
8053417 Hexosylceramides as adjuvants and their uses in pharmaceutical compositions  
The present invention relates to new adjuvants and the uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new compounds useful as adjuvants for...
8053416 Isolation and structure of turbostatins 1-4  
Described herein are novel cerebroside compounds, designated as Turbostatin 1, Turbostatin 2, Turbostatin 3, and Turbostatin 4. These compounds were extracted and isolated from the marine mollusk...
8048860 Butanol extract of Bidens pilosa  
A method of treating a Th1-mediated disorder includes administering to a subject in need of the treatment an effective amount of a compound of the formula I: wherein R1 is H, alkyl, aryl, or...
8048868 Method of preventing preeclampsia  
A method of preventing preeclampsia including administering to a patient during an early stage of pregnancy a prophylactically-effective amount of resibufogenin. The administration of resibufogenin...
8044029 Sulfatides for treatment of autoimmune disorders  
Disclosed herein are methods for the treatment of autoimmune or immune related diseases or disorders. Also disclosed are methods for treating such autoimmune or immune related diseases or disorders...
8026221 Method, composition and kit for antigenic binding of norwalk-like viruses  
A method for detecting a Norwalk-Like Virus (NLV) in a biological sample, comprising the steps of: obtaining a biological sample suspected of containing a NLV; contacting the biological sample with...
8022043 Ceramide derivatives as modulators of immunity and autoimmunity  
α-Galactosylceramides and glycosylceramides (“ceramide-like glycolipids”) that modulate NK T cells. The ceramide-like glycolipids vary in the cytokines induced in NK T cells and vary in the anti...
8003615 Stable vitamin B6 derivative  
A compound represented by the following general formula (I) or a salt thereof: wherein R1 represents a glycosyl group, a phosphate group, or a cyclic phosphate group bound to R2; R2 represents...
7998739 Methods of activating NKT cells  
Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from...
7998943 Core 2 GlcNAc-T inhibitors III  
A method of treating a subject in need of therapy for a condition involving detrimental activity of the enzyme core 2 GlcNAc-T is provided, comprising administration of a therapeutically effective...
7998935 Quinaldine based semisquaraines and squaraine dyes, process for preparation thereof and use thereof  
The present invention provides quinaldine-based semisquaraines, symmetrical and unsymmetrical squaraine dyes represented by the general formulae 1, 2 and 3 and/or pharmaceutically acceptable...
7994141 Compositions comprising compounds of natural origin for damaged skin  
The present invention relates to a skin-protecting composition for the damaged skin, comprising glycyrrhizin, quercetin, rosmarinic acid, madecassic acid, chamazulene, bicalein and emodin. The...
7994140 Classes of compounds that interact with GPCRs  
The present invention relates to a method of identifying a candidate therapeutic agent. The method comprises contacting a G-Protein Coupled Receptor (GPCR) with a compound of General Formula (I),...
7989422 Antibacterial agents  
The present invention, in one aspect, provides a method of inhibiting bacterial growth by contacting bacteria with an effective amount of at least one monosaccharide compound of formula (1) as...
7989423 6″-amino-6″-deoxygalactosylceramides  
This invention relates to galactosylceramide compounds.
7989424 Glucopyranosyloxypyrazole derivatives and use thereof in medicines  
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug; one...
7985435 Triterpene compositions and methods for use thereof  
The invention provides saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic...
7977318 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process  
An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and...
7977319 Ultra-high fiber supplement and method of reducing weight, cardiovascular risks and ingested toxins  
An improved ultra-high fiber supplement that promotes satiety, caloric reduction, and weight loss. The supplement comprises guar, oat, psyllium, locust bean gum, pectin, green tea,...