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6596694 |
Caloporoside derivatives, methods of their preparation and use
The present invention relates to novel caloporoside derivatives and method of their use. The caloporoside derivatives may be formed by fermentation of microorganisms, such as Gloeoporus dichrous...
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6596702 |
Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
The invention provides sports beverages which supply a readily metabolizable, natural carbohydrate, trehalose. The use of trehalose provides twice the concentration of glucose molecules for...
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6596779 |
Stable emulsion, process for the preparation thereof and agent for this purpose
The present invention relates to emulsions which remain perfectly stable over time, prepared from an emulsifier comprising at least one polyglycoside, i.e. polypentoside with or without pohexoside,...
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6589939 |
Camptothecin derivatives having antitumor activity
Camptothecin derivatives of camptothecin of formula (I): wherein the groups R1, R2 and R3 are as defined in the description are disclosed.The compounds of formula (I) are endowed with antitumor...
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6586438 |
Antidiabetic formulation and method
A low dose antidiabetic pharmaceutical formulation is provided, especially adapted for treating Type II diabetes in drug naive patients, which includes a combination of metformin (employed in a...
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6583118 |
Chondroprotective agents
A chondroprotective agent comprising a flavonoid compound of the general formula (I): wherein R1 to R9 are, independently, a hydrogen atom, hydroxyl group, or methoxyl group and X is a single bond...
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6576266 |
Plant extract based on glycerides, a method for the preparation of this extract and a cosmetic composition containing the same
The present invention is concerned with a plant extract comprising a mixture of di-O-D-galactosyl-di-O-acylglyceride with phytosphingolipids and phospholipids, as well as with a method for the...
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6576251 |
Carbohydrate mixture
The invention relates to a carbohydrate mixture for dietetic foods administered by the enteral or parenteral route and pharmaceuticals, characterized in that said mixture consists of (a)...
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6573246 |
Modified ether glyceroglycolipids
This invention provides lipids having: 1) a glycerol backbone; 2) a hydrocarbon chain, preferably saturated and containing 16 or 18 carbon atoms, attached to C-1 of the backbone by an ether...
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6573245 |
Modified polysaccharide adjuvant-protein antigen conjugates, the preparation thereof and the use thereof
The present invention is directed to chemical conjugates (herein referred to as polysaccharide adjuvant-antigen conjugates) that have a polysaccharide backbone capable of binding to the cell...
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6569891 |
Antihypertensive compound from Caesalpinia brasiliensis
A compound isolated from an aqueous leachate of heartwood of “Palo de Brazil” Caesalpinia brasiliensis has antihypertensive activity. The compound was isolated by reversed-phase high pressure liq...
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6569835 |
Combinations with statin and aryl-substituted propanolamine derivatives, their preparation pharmaceuticals comprising them, and their use
Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described. Also described are compounds of formula I in which...
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6566340 |
Aryl-substituted propanolamine derivatives, their preparation, pharmaceuticals comprising them, and their use
Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described. Also described are compounds of formula I in which...
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6566341 |
Derivative of isoindigo, indigo and indirubin for the treatment of cancer
A compound called NATURA, which is a derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and...
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6562792 |
Hygromycin derivatives
The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X, Y, V, W1, W2, Z1 and Z2 are as defined herein. The...
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6558670 |
Vaccine adjuvants
The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an...
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6555372 |
Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
A composition for enhancing immunogenicity of tumor cells or pathogen-infected cells comprising a compound having an α-glycosylceramide structure or a salt or solvate thereof is provided. Tumor ...
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6552089 |
Method of treating or preventing alopecia
The present application discloses a method of treating alopecia which is based on the use of a tellurium compound such as ammonium trichloro(dioxoethylene-O,O-tellurate).
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6552001 |
Method breeding and feeds
A method of rearing useful organisms such as cultured animals which is effective in preventing the organisms from diseases, treating the organisms for diseases or maintaining the health of the...
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6544954 |
Stable galactose injection solutions
The present invention provides stable galactose injection solutions, which contain 1 to 50% by weight of galactose, 0.01 to 1 M of a buffer solution, and 0.01 to 5% of an antioxidant. The preferred...
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6544953 |
Ophthalmic composition
An ophthalmic composition which contains a component A consisting of at least one member selected from the group consisting of polyoxyalkylene block copolymers and their derivatives, and a...
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6544965 |
Compounds with an antioxidant activity, compositions useful as food integrators containing them and process for their preparation
The present invention relates to the use of a compound having general formula (I) as described hereunder wherein R═H (FPA compound) or R═CH3 (FPB compound) for the preparation of compositions wit...
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6541038 |
Method for treating wood with a metal-containing treating agent and wood treated thereby
A method for treating wood, characterized by impregnating wood with a metal-containing treating agent containing lignin and/or lignin derivatives and a metal, a metal compound, and/or a metal ion...
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6541488 |
Compositions for treating arterial thrombosis and a factor Xa inhibitor
The invention relates to the use of direct or indirect selective inhibitors of factor Xa acting via antithrombin III, alone or in combination with one or more compounds with anti-platelet...
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6540999 |
Immunomodulatory methods using Lewisx oligosacchardies
Methods for modulating immune responses are provided. The methods involve contacting an immune cell with an agent that modulates interaction of a compound comprising a Lewis antigen with the immune...
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6537970 |
Pharmaceutical composition
The invention relates to a novel pharmaceutical combination comprising clindamycin and clotrimazole for use for vaginal infections.
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6538027 |
Compositions comprising ratite oil or active fractions thereof and methods of using these composition as insect repellents
This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained...
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6537971 |
Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-&lsqb 4-(2-amin-1-yl-ethoxy)-benzyl&rsqb -1H-indol-5-ols
This invention provides tissue selective estrogens of formula I having the structure wherein:R1 and R2 are independently, hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon...
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6534481 |
Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same
A synthetic polysaccharide including an antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four...
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6534477 |
Production and use of modified cystatins
Cystatins that have been modified by glycosylation in order to enhance stability and activity are disclosed, as are methods of making such cystatins and methods of using such cystatins to inhibit...
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6531453 |
NKT cell activators containing α-glycosylceramides
An objective of the present invention is to provide NKT cell-activating agents, therapeutic agents for autoimmune diseases (for example, systemic lupus erythematosus, systemic sclerosis, ulcerative...
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6531148 |
Therapeutic agents
Therapeutic or preventive agents for diseases requiring apoptosis induction, cancerous diseases, diseases requiring the inhibition of active oxygen production, those requiring the inhibition of...
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6528491 |
Pyranoside derivatives
The present invention relates to new pyranoside derivatives of general formula I, processes for preparing them as well as their use as medicaments:
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6528490 |
Oenothein medicaments
The invention provides medicaments comprising an oenothein, including topical formulations for use as free radical scavengers, or to treat irritation, or to treat inflammation. The oenothein for...
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6528037 |
Method for determining whether a compound is an insulin receptor kinase activator
A method for determining whether a compound is an insulin receptor kinase activator.
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6528058 |
Saponin adjuvant composition
Art adjuvant composition for stimulating an effective immune resposne to an antigenic substance when co-administered to an animal with said antigenic substance, comprising: (a) a saponin with...
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6528497 |
Synthetic polysaccharides, their method of production and pharmaceutical compositions containing same
Novel synthetic polysaccharides for use in the treatment of pathologies associated with a coagulation dysfunction.
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6524584 |
Saponin compositions and uses thereof
The present invention is in the field of medicinal chemistry. In particular, the invention is related to vaccines comprising novel combinations of saponin adjuvants, to pharmaceutical compositions...
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6518248 |
Method of treating gastric or colon cancer by administration of a sulfoquinovosylacylglycerol ester
An anticancer drug includes a compound represented by Formula (1): where R101 represents an acyl moiety of a saturated higher fatty acid, and R102 represents a hydrogen atom or an acyl moiety of a...
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6518250 |
Agent for preventing and curing hindrance of ischemic reperfusion
An agent for preventing and curing the hindrance of ischemic reperfusiton is disclosed which has as an active component thereof a chromanol glycoside represented by the following general formula:...
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6518302 |
Remedies
Compounds represented by general formula (I) wherein X represents OH or OSO3H; and R represents a substituent other than OH which allows, after leaving, the induction of unsaturated bonds into the...
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6515020 |
Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
A pharmaceutical product which comprises admixed or separately packaged (A) L-Carnitine or an alkanoyl L-canitine and (B) a trihydroxy- or tetrahydroxystilbene such as resveratrol is useful for the...
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6511965 |
Ether type lipid A 1-carboxylic acid analogs
A compound of formula (I) below, which exhibits excellent macrophage activity inhibitory action, is useful for the treatment or prophylaxis of inflammatory disorders, autoimmune diseases or...
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6506386 |
Vaccine comprising an iscom consisting of sterol and saponin which is free of additional detergent
The present invention provides an improved adjuvant formulation and a process for producing said adjuvant. The adjuvant comprises an ISCOM structure comprising a saponin, said ISCOM structure being...
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6506734 |
20(S) camptothecin glycoconjugates
The present invention relates to glycoconjugates of 20(S)-camptothecin, in which a 3-O-methylated β-L-fucose unit is linked to the 20-hydroxyl group of a camptothecin derivative via a ...
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6503885 |
Carboxymethylgalactose derivatives
Carboxymethylgalactose derivatives represented by general formula (1); and salts thereof, which exhibit reactivity to selectins and are useful as inhibitors against selectin-related diseases such...
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6500810 |
Method of regulating expression of adhesion molecules on circulating leukocytes
A method to inhibit inflammation in a mammal is disclosed. The method includes administering to the mammal a composition comprising a phospholipid, which can be lysophosphatidic acid. The...
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6497901 |
Resorbable matrices for delivery of bioactive compounds
This invention relates generally to the production and use of inorganic-conditioning agent complexes for the controlled release of compounds including medicinals. Advantageously, the inorganic used...
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6498145 |
Use of purified SDG as a hypotensive (vasodilator) agent
The compound secoisolariciresinol diglucoside (SDG), obtained from flaxseed is used for treating hypertension or for reducing or preventing the development of elevated blood pressure in humans or...
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6495140 |
Process for the isolation, recovery and purification of non-polar extractives
A process is described for the isolation, recovery and purification of non-polar extractives using one or more extracting solvents from the group of lower alcohols, ketones, and water. The...
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