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6552001 |
Method breeding and feeds
A method of rearing useful organisms such as cultured animals which is effective in preventing the organisms from diseases, treating the organisms for diseases or maintaining the health of the...
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6548484 |
Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation
Hydrophilic transportable N-linked glycosyl dopaminergic prodrug compounds according to FORMULA V, wherein, Ring 1 comprises a cyclic or heterocyclic ring, or aryl or heteroaryl ring, all of...
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6544518 |
Vaccines
The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an...
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6544965 |
Compounds with an antioxidant activity, compositions useful as food integrators containing them and process for their preparation
The present invention relates to the use of a compound having general formula (I) as described hereunder wherein R═H (FPA compound) or R═CH 3 (FPB compound) for the preparation of...
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6544953 |
Ophthalmic composition
An ophthalmic composition which contains a component A consisting of at least one member selected from the group consisting of polyoxyalkylene block copolymers and their derivatives, and a...
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6544954 |
Stable galactose injection solutions
The present invention provides stable galactose injection solutions, which contain 1 to 50% by weight of galactose, 0.01 to 1 M of a buffer solution, and 0.01 to 5% of an antioxidant. The preferred...
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6541038 |
Method for treating wood with a metal-containing treating agent and wood treated thereby
A method for treating wood, characterized by impregnating wood with a metal-containing treating agent containing lignin and/or lignin derivatives and a metal, a metal compound, and/or a metal ion...
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6541461 |
Compounds having antiviral activity
In order to provide the anti-retrovirus active compound with low anti-coagulant action and low cytotoxicity, compounds comprising glycoside or the salt thereof wherein lipid is linked to position 2...
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6541462 |
Sphingomyelin enhancement of tumor therapy
Cytotoxic tumor therapy in a patient is enhanced by co-administration of sphingomyelin. The invention most likely enhances a tumor cell's ability to undergo ceramide-induced apoptosis by increasing...
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6541488 |
Compositions for treating arterial thrombosis and a factor Xa inhibitor
The invention relates to the use of direct or indirect selective inhibitors of factor Xa acting via antithrombin III, alone or in combination with one or more compounds with anti-platelet...
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6540999 |
Immunomodulatory methods using Lewisx oligosacchardies
Methods for modulating immune responses are provided. The methods involve contacting an immune cell with an agent that modulates interaction of a compound comprising a Lewis antigen with the immune...
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6538027 |
Compositions comprising ratite oil or active fractions thereof and methods of using these composition as insect repellents
This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained...
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6537971 |
Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-&lsqb 4-(2-amin-1-yl-ethoxy)-benzyl&rsqb -1H-indol-5-ols
This invention provides tissue selective estrogens of formula I having the structure wherein: R 1 and R 2 are independently, hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7...
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6537970 |
Pharmaceutical composition
The invention relates to a novel pharmaceutical combination comprising clindamycin and clotrimazole for use for vaginal infections.
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6534481 |
Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same
A synthetic polysaccharide including an antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four...
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6534477 |
Production and use of modified cystatins
Cystatins that have been modified by glycosylation in order to enhance stability and activity are disclosed, as are methods of making such cystatins and methods of using such cystatins to inhibit...
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6531453 |
NKT cell activators containing α-glycosylceramides
An objective of the present invention is to provide NKT cell-activating agents, therapeutic agents for autoimmune diseases (for example, systemic lupus erythematosus, systemic sclerosis, ulcerative...
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6531148 |
Therapeutic agents
Therapeutic or preventive agents for diseases requiring apoptosis induction, cancerous diseases, diseases requiring the inhibition of active oxygen production, those requiring the inhibition of...
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6528037 |
Method for determining whether a compound is an insulin receptor kinase activator
A method for determining whether a compound is an insulin receptor kinase activator.
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6528497 |
Synthetic polysaccharides, their method of production and pharmaceutical compositions containing same
Novel synthetic polysaccharides for use in the treatment of pathologies associated with a coagulation dysfunction.
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6528058 |
Saponin adjuvant composition
Art adjuvant composition for stimulating an effective immune resposne to an antigenic substance when co-administered to an animal with said antigenic substance, comprising: (a) a saponin with...
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6528491 |
Pyranoside derivatives
The present invention relates to new pyranoside derivatives of general formula I, processes for preparing them as well as their use as medicaments:
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6528490 |
Oenothein medicaments
The invention provides medicaments comprising an oenothein, including topical formulations for use as free radical scavengers, or to treat irritation, or to treat inflammation. The oenothein for...
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6524832 |
DNA damaging agents in combination with tyrosine kinase inhibitors
The present invention relates to the signalling pathways connecting DNA damage, such as that induced by ionizing radiation or alkylating agents, and phosphorylation by tyrosine kinases.
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6524584 |
Saponin compositions and uses thereof
The present invention is in the field of medicinal chemistry. In particular, the invention is related to vaccines comprising novel combinations of saponin adjuvants, to pharmaceutical compositions...
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6518248 |
Method of treating gastric or colon cancer by administration of a sulfoquinovosylacylglycerol ester
An anticancer drug includes a compound represented by Formula (1): where R 101 represents an acyl moiety of a saturated higher fatty acid, and R 102 represents a hydrogen atom or an acyl...
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6518302 |
Remedies
Compounds represented by general formula (I) wherein X represents OH or OSO 3 H; and R represents a substituent other than OH which allows, after leaving, the induction of unsaturated bonds into...
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6518250 |
Agent for preventing and curing hindrance of ischemic reperfusion
An agent for preventing and curing the hindrance of ischemic reperfusiton is disclosed which has as an active component thereof a chromanol glycoside represented by the following general formula: ...
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6515020 |
Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
A pharmaceutical product which comprises admixed or separately packaged (A) L-Carnitine or an alkanoyl L-canitine and (B) a trihydroxy- or tetrahydroxystilbene such as resveratrol is useful for the...
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6511965 |
Ether type lipid A 1-carboxylic acid analogs
A compound of formula (I) below, which exhibits excellent macrophage activity inhibitory action, is useful for the treatment or prophylaxis of inflammatory disorders, autoimmune diseases or...
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6506734 |
20(S) camptothecin glycoconjugates
The present invention relates to glycoconjugates of 20(S)-camptothecin, in which a 3-O-methylated β-L-fucose unit is linked to the 20-hydroxyl group of a camptothecin derivative via a...
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6506386 |
Vaccine comprising an iscom consisting of sterol and saponin which is free of additional detergent
The present invention provides an improved adjuvant formulation and a process for producing said adjuvant. The adjuvant comprises an ISCOM structure comprising a saponin, said ISCOM structure being...
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6503885 |
Carboxymethylgalactose derivatives
Carboxymethylgalactose derivatives represented by general formula (1); and salts thereof, which exhibit reactivity to selectins and are useful as inhibitors against selectin-related diseases...
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6500810 |
Method of regulating expression of adhesion molecules on circulating leukocytes
A method to inhibit inflammation in a mammal is disclosed. The method includes administering to the mammal a composition comprising a phospholipid, which can be lysophosphatidic acid. The...
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6498145 |
Use of purified SDG as a hypotensive (vasodilator) agent
The compound secoisolariciresinol diglucoside (SDG), obtained from flaxseed is used for treating hypertension or for reducing or preventing the development of elevated blood pressure in humans or...
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6497901 |
Resorbable matrices for delivery of bioactive compounds
This invention relates generally to the production and use of inorganic-conditioning agent complexes for the controlled release of compounds including medicinals. Advantageously, the inorganic used...
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6495524 |
Benzo&lsqb b&rsqb pyran derivatives useful as external agents for the skin
To provide an external agent for thee skin that not only exhibits excellent effects of prevention and amelioration of skin pigmentation but also has no fear of giving adverse influences to the skin...
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6495140 |
Process for the isolation, recovery and purification of non-polar extractives
A process is described for the isolation, recovery and purification of non-polar extractives using one or more extracting solvents from the group of lower alcohols, ketones, and water. The...
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6492335 |
Glycoconjugates from modified camptothecin derivatives (20-O-linkage)
The present invention relates to glycoconjugates of camptothecin derivatives in which at least one carbohydrate component is linked via suitable spacers with the 20-hydroxyl group of a camptothecin...
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6492338 |
Therapeutic agents
Therapeutic or preventive agents for diseases due to the action of aldose reductase; and aldose reductase inhibitors, characterized by containing at least one compound having an aldose reductase...
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6492339 |
Compositions comprising D-chiro inositol and sulfonylureas and methods of treatment thereof
The present invention provides compositions comprising synergistically effective amounts of D-chiro-inositol and sulfonylureas. The present invention also provides methods to treat a subject with...
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6492337 |
Galactosylceramide, glucosylceramide, lactosylceramide, and specific catchers therefor for use in the prophylaxis or therapy of prediabetes, diabetes and/or associated complication
The use of glycolipids, in particular galactosylceramide, glucosylceramide and lactosylceramide, and specific catchers therefor (antibodies or lectins), in particular monoclonal antibodies, for use...
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6492342 |
Hygromycin A prodrugs
This invention relates to compounds of the formula and to pharmaceutically acceptable salts and solvates thereof, wherein a, b, X, Y, Z, R 1 , R 2 , and R 3 are as defined herein. The compounds...
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6492350 |
Chitin oligosaccharides and/or chitosan oligosaccharides for preventing or treating common cold or treating pain
A new method is presented which is useful in the prevention of the common cold (also called non-allergic rhinitis, viral upper respiratory tract infection, viral URI, etc and for this presentation...
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6492332 |
Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
This invention relates to a method of inhibiting tumor cell adhesion, pain, and inflammation at a wound during a surgical procedure by delivering an irrigation solution containing a tumor cell...
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6492336 |
Peritoneal dialysis fluid
Peritoneal dialysis fluids and the use thereof for performing peritoneal dialysis are disclosed. The peritoneal dialysis fluid comprises a physiologically acceptable aqueous solution containing...
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6491919 |
Aqueous immunologic adjuvant compostions of monophosphoryl lipid A
An aqueous adjuvant composition comprising an attenuated lipid A derivative and a non-immunostimulatory surfactant or surfactants enhances the immunological response in a warm blooded animal to a...
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6489301 |
Solid pharmaceutical preparation for dialysis and a process for producing the same
There is provided a solid pharmaceutical preparation for dialysis consisting of one composition, which is excellent in uniformity of the ingredients contained therein, is capable of preventing not...
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6489302 |
Saccharide conjugates
This invention relates to a conjugate, comprising a saccharide and one or more therapeutic or diagnostic agents, as well as the use of the conjugate. The conjugate of the present invention may be...
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6486129 |
Antithrombotic compounds
The present invention relates to compounds of formula (1), wherein R 1 is phenyl, naphthyl, 1,2,3,4-tetrahydronaphthyl, (iso)quinolinyl, tetrahydro(iso)quinolinyl, 3,4-dihydro-1H-isoquinolinyl,...
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