|
Match
|
Document |
Document Title |
|
|
5830873 |
Propiophenone derivative and a process for preparing the same
A propiophenone derivative of the formula I!: ##STR1## wherein X is O, S or methylene, OY is a protected or unprotected OH, Z is β-D-glucopyranosyl or 4-O-(α-D-glucopyranosyl)-β-D-glucopyranosyl or...
|
|
|
5830920 |
Sulfuric acid esters of sugar alcohols
Compounds of the formula ##STR1## wherein n1 -n9 are each independently 0 or 1; m1 -m9 are each independently 0 or 1, but with the proviso that at least one of m1, m2 and m3, at least one of m4, m5...
|
|
|
5830887 |
Health supplements containing phyto-oestrogens, analogues or metabolites thereof
Compositions enriched with natural phyto-oestrogens or analogues thereof selected from Genistein, Daidzein, Formononetin and Biochanin A. These may be used as food additives, tablets or capsules...
|
|
|
5827828 |
Sulfated glycolipids and antibodies thereto for prophylaxis or therapy of diabetes
Methods for the treatment of prediabetes or diabetes in an individual comprise administering to the individual a therapeutically active agent comprising a glycolipid having a galactose-3-O-sulfate...
|
|
|
5827830 |
Plasmalopsychosines and plasmalocerebrosides
An isolated plasmalopsychosine selected from the group consisting of compound A and compound B: ##STR1## wherein n1 is 0-50 or an isolated synthetic plasmalocerebroside selected from the group...
|
|
|
5817634 |
Methods of treating diabetes mellitus and clycogen storage disease
This present invention provides a method and compounds for priming the incorporation of cellular glucose into an oligosaccharide in a cell comprising administering to the cell a priming amount of a...
|
|
|
5814615 |
Antibiotic LL-E19020 Alpha1
The invention provides an antibiotic designated LL-E19020 Alpha1 which is derived from the micro-organism Streptomyces lydicus ssp. tanzanius NRRL 18036.
|
|
|
5814613 |
Antibiotic LL-E19020 gamma
The invention provides an antibiotic designated LL-E19020 Gamma which is derived from the microorganism Streptomyces lydicus ssp. tanzanius NRRL 18036.
|
|
|
5814614 |
Substituted glucose compounds for toxic metal ion removal from the body
According to the present invention, a pharmaceutical composition that comprises a compound which is a 2-deoxy-D-glucopyranose substituted in the 2 position and is of the general formula (I):...
|
|
|
5811405 |
Multiply fucosylated dicarboxylic acids possessing antiadhesive properties
The invention relates to multiply fucosylated dicarboxylic acid derivatives possessing antiadhesive properties, to a process for preparing them, to their use, and to pharmaceuticals and diagnostic...
|
|
|
5811404 |
Sialyl Lex analogues as inhibitors of cellular adhesion
The present invention relates to analogues of sialyl Lex the inhibit cellular adhesion between a selectin and cell that express sialyl Lex on their surfaces, as well as methods and compositions...
|
|
|
5807833 |
Hydroxyethyl starch and use thereof as an absorbable mechanical barrier and intracavity carrier device
Hydroxyethyl starch (HES) and use thereof in methods are provided for reducing or preventing of adhesion formation between tissue surfaces, e.g., organ surfaces, in body cavities following surgical...
|
|
|
5798343 |
7-O-Carbamoylheptose derivatives, process for their production and their use in treating pseudomonas infections
The invention describes 7-O-carbamoyl heptose derivatives of general formula (I) in which R is the substituent R1 or a group of general formula (II) in which R1 is a hydrogen atom, a methyl group...
|
|
|
5795869 |
Sulfated lyso-ganglioside derivatives
Semisynthetic analogues of gangliosides selected from the group consisting of N-sulfo-, N-hydrocarbyl-sulfonyl- and N-hydrocarbyloxy-sulfonyl-N,N'-dilyso-gangliosides and the N'-acyl derivatives...
|
|
|
5795874 |
Water soluble antibiotics
The compound of the formula I ##STR1## wherein R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein, are described. These compounds are antibacterial agents.
|
|
|
5789385 |
Sialyl Lewisx mimetics containing phenyl backbones
Compounds that possess selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs, derivatives, or mimics of these groups,...
|
|
|
5788985 |
Vaccine composition for eliciting an immune response against N-glycolylated gangliosides and its use for cancer treatment
The invention provides novel uses for n-glycolylated gangliosides, or derivatives and/or oligosaccharides thereof. The invention further provides methods of obtaining such gangliosides, as well as...
|
|
|
5780443 |
Water-soluble retinoids
The invention relates to water-soluble sugar retinoids (I) and to their preparation and the use thereof as medicaments and in the cosmetic sector, wherein X is a sugar radical attached at an oxygen...
|
|
|
5780442 |
Orthosomycins from micromonospora carbonacae
Orthosomycins have been isolated from the fermentation broth of the microorganism Micromonospora Carbonacea var Africana designated SCC 2146. These compounds are antibacterial agents. Compositions...
|
|
|
5780445 |
Tocopheryl glycosides, their preparation, and their use as surfactants, as antioxidants and as the active substance preventing cell ageing in cosmetic or pharmaceutical preparations
Tocopheryl glycosides of the general formula ##STR1## or of the general formula ##STR2## where n can adopt values of 0-6 and where R represents a radical from the group consisting of H, branched...
|
|
|
5780441 |
Sphingoglycolipid compounds and therapeutic uses thereof
The present invention relates to a sphingoglycolipid represented by the formula (I): ##STR1## wherein R1, R2 and R5 represent H or a specific monosaccharide; R3 and R6 represent H or OH,...
|
|
|
5776460 |
Processed ginseng product with enhanced pharmacological effects
A processed ginseng product with enhanced pharmacological effects is provided due to a heat-treatment at a high temperature of 120° to 180° C. for 0.5 to 20 hours so as to make a ratio of g...
|
|
|
5773420 |
Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation
This invention relates to acylated benzylglycosides and a method for their use as smooth muscle cell proliferation inhibitors and as therapeutic compositions for treating diseases and conditions...
|
|
|
5773421 |
Antifungal fusacandins
Novel antifungal agents having the formula: ##STR1## wherein R is hydrogen or --C(O)--R1 wherein R1 is alkenyl, C2 -C12 -alkyl, aryl, arylalkenyl, arylalkyl, aryl-aryl-, arylalkoxy-aryl-,...
|
|
|
5773001 |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from...
|
|
|
5773419 |
Method of treating cancer with tannic acid
A pharmaceutical composition including tannic acid and tannin complexes, and a method of treating cancer with tannic acid and tannin complexes.
|
|
|
5770204 |
Composition for mucosa treatment with saponin
The instant invention is a composition based upon a triterpene saponin having a particular application for inclusion in the diets of vertebrates to reduce or eliminate the colonization of bacteria...
|
|
|
5767095 |
Anti-inflammatory compositions containing monogalactosyl dieicosapentaenoyl glycerol and methods relating thereto
Disclosed are topical anti-inflammatory compositions containing 0.1% to 10% by weight of a monogalactosyl dieicosapentaenoyl glycerol having esterified eicosapentaenoic acid residues (MGDG-EPA);...
|
|
|
5767094 |
Propiophenone derivative and processes for preparing the same
A propiophenone derivative the formula I!: ##STR1## wherein R' is a lower alkanoyl group and R" is a hydrogen atom, or R' is a hydrogen atom and R" is a lower alkoxycarbonyl group, or a...
|
|
|
5767092 |
Treatment of radiation-damaged bone marrow using galactosyl ceramides
The present invention relates to a pharmaceutical composition (a marrow cell proliferation accelerator, a radioprotective agent, a therapeutic agent for thrombocytopenia) comprising a compound...
|
|
|
5767149 |
α-glycosyl-L-ascorbic acid, and it's preparation and uses
α-Glycosyl-L-ascorbic acid exhibiting no direct reducing activity is formed in a solution containing L-ascorbic acid and an α-glucosyl saccharide when subjected to the action of a s...
|
|
|
5767093 |
Methods for attenuating antibody-mediated xenograft rejection in human recipients
Antibody-mediated xenograft rejection is attenuated by parenterally administering a xenoantibody-inhibiting amount of an identified carbohydrate xenoantigen to the recipient shortly before graft...
|
|
|
5767104 |
Use of sulfated saccharides to treat baldness
A method of treating and/or preventing alopecia (baldness, deficient hair growth) comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a...
|
|
|
5763413 |
Lewis-associated compound, process for producing the same, and anti-inflammatory
A Lewis-associated compound, represented by general formula (I), a process for producing the same, and an anti-inflammatory, wherein R1 and R3 represent each hydrogen, m SO3 H or CH2 COOH; R2...
|
|
|
5760008 |
Method and compositions for treating malignant tumors and inhibiting metastases of malignant tumors
According to the present invention, a substrate for cytochrome p450 which, after oxidation by cytochrome p450, reacts with thiol groups is conjugated to a saccharide to provide a tumor-specific...
|
|
|
5756470 |
Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
Hypocholesterolemic sugar-substituted 2-azetidinones are disclosed, as well as a method of lowering cholesterol by administering said compounds, pharmaceutical compositions containing them, and the...
|
|
|
5756471 |
Use of a sophorolipid to provide free radical formation inhibiting activity or elastase inhibiting activity
The present invention relates to a cosmetic and/or dermatological composition comprising at least one sophorolipid in its crude or acid form or associated with a monovalent or divalent salt. The...
|
|
|
5753631 |
Intercellular adhesion mediators
The present invention is directed towards compositions and methods for reducing or controlling inflammation and for treating inflammatory disease processes and other pathological conditions...
|
|
|
5753630 |
Method for treating and inhibiting gastric and duodenal ulcers
A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of Formula I...
|
|
|
5750508 |
Sialic acid/fucose based medicaments
Compounds that are synthetically inexpensive to make relative to the naturally occurring selectin ligands and that retain selectin binding activity are described that have a three-dimensionally...
|
|
|
5750150 |
Compositions for treating affected tissues, method for the preparation and usage thereof
Injectable compositions for treating affected tissues are prepared by formulating sodium hydrogen sulfite with all other components except tannic acid to yield a first mixture and adding tannic...
|
|
|
5747463 |
Malonate derivatives of glycolipids as cell adhesion inhibitors
There is provided a novel series of malonate derivatives of glycolipid compounds of the formula ##STR1## wherein R is an acyl residue of a fatty acid: R1 is --(CHCH)m --(CH2)n --CH3 ; R2, R3, R...
|
|
|
5747461 |
Synergistic administration of cyclosporine and fructose diphosphate
This invention discloses a method of using fructose-1,6-diphosphate (FDP) to help suppress the rejection of internal organs such as kidneys, hearts, etc. At least three major advantages of FDP in...
|
|
|
5739116 |
Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents
This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from...
|
|
|
5739115 |
Sulfated maltooligosaccharides with heparin-like properties
A novel class of highly sulfated maltooligosaccharide having heparin-like activity is described, as well as methods for using these oligosaccharides to treat certain diseases including cancer, and...
|
|
|
5739117 |
Agent for improving cerebral metabolism including glucose ester derivatives
An agent for improvement of cerebral metabolism, containing as active ingredient a glucose ester derivative presented by the formula: ##STR1## and wherein the anomeric substitute in the formula is...
|
|
|
5736522 |
Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition
A compound of the formula (I): ##STR1## wherein R1 and R2 are, independently, a hydrogen atom, a monosaccharide residue, a protected monosaccharide residue, or a protecting group for hydroxyl...
|
|
|
5736523 |
Antineoplastic heteronapthoquinones
This invention relates to a naphthoquinone derivatives, to processes and to intermediates for preparing these derivatives, to pharmaceutical composition and to the use of these derivatives as...
|
|
|
5733892 |
Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same
This invention relates to compounds prepared by linking glycosaminoglycan to phospholipid or lipid, which are expected to exert a pharmacological effect for inhibiting metastasis because of their...
|
|
|
5731292 |
Dihydrochalcone derivatives which are hypoglycemic agents
A method for prophylaxis or treatment of diabetes, which comprises administering to a patient with diabetes an effective amount of a dihydrochalcone derivative of the formula I!: ##STR1## wherein...
|