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5919769 |
Fucose derivatives, drugs containing the same as active ingredient, and intermediates for producing the same
A compound of the formula (I): ##STR1## wherein X 1 is a group of one of the following formulae (1), (2) and (3): ##STR2## R 1 is a branched long chain alkyl group, R 2 is --CONHR 3 , a carboxyl...
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5916880 |
Reduction of skin wrinkling using sulphated sugars
Use of a sulphated saccharide or a salt or complex thereof for the preparation of a medicament for topical application to the skin or to any non-gastrointestinal, non-oral mucosal surface of an...
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5916579 |
Process for combating adiposity and compositions which may be used for this purpose
The invention relates to a treatment and/or prevention of the problems of adiposity, with the aim being to obtain a cosmetic and/or therapeutic slimming effect which is generalized or localized on...
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5908836 |
Protecting skin from radiation damage using sulphated sugars
Use of a sulphated saccharide or a salt or complex thereof for the preparation of a medicament for topical application to the skin or to any non-gastrointestinal, non-oral mucosal surface of an...
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5906979 |
Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility
This invention relates to compositions and methods for decreasing the level of serum insulin, triglycerides, cholesterol, and/or free and total testosterone, and/or improving ovulation, and/or...
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5905071 |
Glycosylamides of 2-aminoacylamino-2-deoxy sugars
The present invention relates to (2-aminoacylamino-2-deoxy-glycosyl)-amides, which are substituted on the nitrogen atom of the amino acid, of the general formula (I) ##STR1## in which the...
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5891854 |
Cosmetic formulations having an effective content of glycosyl glycerides
Cosmetic ceutical formulations characterized by an effective, content of pharmaceutically and/or cosmetically unobjectionable hexosyl glycerides and/or (hexosyl)hexosyl glycerides.
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5891727 |
Acidic polycyclic ether useful as an anticoccidial agent and as a growth promotant
An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53676. This novel antibiotic...
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5888520 |
Composition, barrier film, and method for preventing contact dermatitis
The present invention relates to a composition, and a method for preventing or reducing contact dermatitis. The composition contains a polysaccharide; a low molecular weight, synergistic...
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5885968 |
Triantennary cluster glycosides, their preparation and use
Triantennary cluster glycoside, wherein each glycoside residue is attached to the branching point of the cluster by a spacer of a long, flexible, hydrophilic chain comprising at least 4 atoms in...
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5883079 |
Method for inhibiting H. pylori infection in mammalian tissue
A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of Formula I ...
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5880160 |
Colchicine derivatives, the use thereof and formulations containing them
The present invention relates to novel colchicine derivatives having antiproliferative, antineoplastic, antiinflammatory and muscle relaxant activities; said derivatives include novel colchine...
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5880100 |
Method for inhibiting binding of human lens cells
The present invention provide a method of inhibiting an irregular binding of human cells caused by specific adhesion of Lewis x glycolipids by administering any of an oligosaccharide having a...
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5877157 |
Modified kojibioside analogues
Disclosed are novel analogues of kojibiose and pharmaceutical compositions comprising such analogues.
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5874411 |
Oligosaccharide glycosides having mammalian immunosuppresive and tolerogenic properties
Disclosed are novel oligosaccharide glycosides having mammalian immunosuppressive and tolerogenic properties, pharmaceutical compositions containing such oligosaccharide glycosides and to methods...
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5869460 |
Sulfated and phosphated saccharide derivatives, process for the preparation of the same and use thereof
There are described sulfated and phosphated saccharide erivatives of the Formula ##STR1## wherein R 1 is hydrogen atom or a residue of sulfate, phosphate or L-fucose; R 2 , R 3 and R 4 are...
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5869459 |
Frozen rehydration formulation and delivery system therefor
A rehydrating freezer pop provides a convenient and effective way of replenishing lost fluid and electrolytes. The frozen formulation masks unpleasant tastes of electrolyte and is readily consumed...
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5861048 |
Phosphorylated saccharide and method for producing the same
Phosphorylated saccharide of the present invention includes at least one phosphate group in its molecule, selected from the group consisting of glucan, mannan, dextran, agar, cyclodextrin,...
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5858985 |
Treatment of asthma with fructose-1,6-diphosphate
Fructose-1,6-diphosphate (FDP), a sugar-phosphate compound, can be useful in treating asthma, when administered as an inhalable drug, either by itself or as a component of a mixed formulation. On a...
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5854218 |
Sialyl Le.sup.x analogues as inhibitors of cellular adhesion
The present invention relates to analogues of sialyl Le x that inhibit cellular adhesion between a selectin and cells that express sialyl Le x on their surfaces, as well as methods and...
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5849274 |
Stable light protection preparations containing surface-active glucose derivatives and water-soluble UV filters
Cosmetic or pharmaceutical O/W emulsions which contain (a) one or more surface-active substances selected from the group consisting of glucose derivatives of the structural formula ##STR1## in...
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5849717 |
O-sulfated gangliosides and lyso-ganglioside derivatives
Disclosed are derivatives of gangliosides and of N-acyl-N-lyso-gangliosides, of N'-acyl-N'-lyso-gangliosides and N,N'-di- or poly-acyl-N,N'-di-lyso-gangliosides, in which at least one of the...
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5849716 |
Sphingoglycolipids, their preparation, and therapeutic methods of use
The present invention relates to a sphingoglycolipid represented by the following formula (I) which is effective at a small dose and has an anti-tumor activity and an immunostimulating effect with...
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5846944 |
Purified SDG as an antioxidant
The compound secoisolariciresinal diglucoside (SDG), obtained from flaxseed is used for reducing or preventing the development of hypercholesterolemic atherosclerosis and for reducing total...
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5846943 |
Solid support matricles containing a toxin binding oligosaccharide
Disclosed are novel solid support matrices having a toxin-binding oligosaccharide covalently attached to a solid support through a linking arm which has at least 8 atoms separating the...
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5843907 |
Pharmaceutical composition containing 2-O-α-d-glucopyranosyl-l-ascorbic acid
2-O-α-D-Glucopyranosyl-L-ascrobic acid is crystallizable in its supersaturated solution. Crystalline 2-O-α-D-glucopyranosyl-L-ascorbic acid is substantially nonhygroscopic, free flowing, free of...
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5843908 |
Pradimicins l and fl, and derivatives thereof
The present invention relates to novel antifungal antibiotics herein designated as pradimicin L and pradimicin FL, and derivatives thereof. Pradimicins L and FL are produced by Actinomadura...
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5844000 |
Propenone oxime ethers and pharmaceutical compositions containing them
This invention relates to novel propenone oxime ethers, methods of preparing them and pharmaceutical compositions containing them. The compounds have the formula: ##STR1## wherein R 1 is H, or...
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5840703 |
Phase transfer catalyst for use in the synthesis of polyol fatty acid polyesters
A reaction mixture for manufacturing polyol fatty acid polyesters comprises a polyol, a fatty acid lower alkyl ester, a base initiator and a phase transfer catalyst. The phase transfer catalyst can...
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5840702 |
Cystic fibrosis treatment
The present invention provides a method of stimulating expression of a functional full-length cystic fibrosis transmembrane conductance regulator protein in an individual in need of such treatment,...
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5837695 |
Fluorescent chlamydia antigen substrate
The present invention relates to a unique fluorescently labeled Chlamydial antigen. This fluorescently labeled Chlamydial antigen is useful in immunoassay-type formatted systems for the detection...
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5837689 |
Sialyl lewis-x mimetics containing naphthyl backbones
Compounds that possess selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs, derivatives, or mimics of these groups,...
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5837256 |
Method for treatment of Lupus nephritis
It has been found that by administering secoisolariciresinol 2,3-bis(3-methyl-4-hydroxybenzyl)butane-1,4-diol! from flaxseed in substantially pure form to a human or non-human animal, lupus...
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5834437 |
Asiatic acid derivatives its manufacturing method and dermatological agent containing it
The object of the present invention is to provide asiatic acid derivatives, its pharmaceutically acceptable salts or esters. Asiatic acid, its trisaccharide asiaticoside and mddecassic acid,...
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5833960 |
Foaming light protection preparations containing water-soluble light protection filters and surface-active substances
Active substance combinations of (a) one or more surface-active substances selected from the group comprising glucose derivatives, (b) one or more surface-active substances selected from the...
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5830887 |
Health supplements containing phyto-oestrogens, analogues or metabolites thereof
Compositions enriched with natural phyto-oestrogens or analogues thereof selected from Genistein, Daidzein, Formononetin and Biochanin A. These may be used as food additives, tablets or capsules...
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5830920 |
Sulfuric acid esters of sugar alcohols
Compounds of the formula ##STR1## wherein n 1 -n 9 are each independently 0 or 1; m 1 -m 9 are each independently 0 or 1, but with the proviso that at least one of m 1 , m 2 and m 3 , at...
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5830873 |
Propiophenone derivative and a process for preparing the same
A propiophenone derivative of the formula I!: ##STR1## wherein X is O, S or methylene, OY is a protected or unprotected OH, Z is β-D-glucopyranosyl or...
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5830872 |
Esters of D-mannose or of xylitol and their use as medicaments
Esters associating phenylacetic, 3-phenylpropionic, 4-phenylbutyric and n-butyric acids with Su(OH) n monosaccharides or sugar alcohols, of general formula (I), in which the Su(OH) n precursor is...
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5827828 |
Sulfated glycolipids and antibodies thereto for prophylaxis or therapy of diabetes
Methods for the treatment of prediabetes or diabetes in an individual comprise administering to the individual a therapeutically active agent comprising a glycolipid having a galactose-3-O-sulfate...
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5827830 |
Plasmalopsychosines and plasmalocerebrosides
An isolated plasmalopsychosine selected from the group consisting of compound A and compound B: ##STR1## wherein n1 is 0-50 or an isolated synthetic plasmalocerebroside selected from the group...
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5817634 |
Methods of treating diabetes mellitus and clycogen storage disease
This present invention provides a method and compounds for priming the incorporation of cellular glucose into an oligosaccharide in a cell comprising administering to the cell a priming amount of a...
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5814613 |
Antibiotic LL-E19020 gamma
The invention provides an antibiotic designated LL-E19020 Gamma which is derived from the microorganism Streptomyces lydicus ssp. tanzanius NRRL 18036.
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5814614 |
Substituted glucose compounds for toxic metal ion removal from the body
According to the present invention, a pharmaceutical composition that comprises a compound which is a 2-deoxy-D-glucopyranose substituted in the 2 position and is of the general formula (I):...
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5814615 |
Antibiotic LL-E19020 Alpha.sub.1
The invention provides an antibiotic designated LL-E19020 Alpha 1 which is derived from the micro-organism Streptomyces lydicus ssp. tanzanius NRRL 18036.
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5811404 |
Sialyl Le.sup.x analogues as inhibitors of cellular adhesion
The present invention relates to analogues of sialyl Le x the inhibit cellular adhesion between a selectin and cell that express sialyl Le x on their surfaces, as well as methods and compositions...
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5811405 |
Multiply fucosylated dicarboxylic acids possessing antiadhesive properties
The invention relates to multiply fucosylated dicarboxylic acid derivatives possessing antiadhesive properties, to a process for preparing them, to their use, and to pharmaceuticals and diagnostic...
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5807833 |
Hydroxyethyl starch and use thereof as an absorbable mechanical barrier and intracavity carrier device
Hydroxyethyl starch (HES) and use thereof in methods are provided for reducing or preventing of adhesion formation between tissue surfaces, e.g., organ surfaces, in body cavities following surgical...
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5798343 |
7-O-Carbamoylheptose derivatives, process for their production and their use in treating pseudomonas infections
The invention describes 7-O-carbamoyl heptose derivatives of general formula (I) in which R is the substituent R 1 or a group of general formula (II) in which R 1 is a hydrogen atom, a methyl...
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5795869 |
Sulfated lyso-ganglioside derivatives
Semisynthetic analogues of gangliosides selected from the group consisting of N-sulfo-, N-hydrocarbyl-sulfonyl- and N-hydrocarbyloxy-sulfonyl-N,N'-dilyso-gangliosides and the N'-acyl derivatives...
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