Matches 101 - 150 out of 340 < 1 2 3 4 5 6 7 >
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6340679 Guanidine derivatives as inhibitors of cell adhesion  
The present invention relates to acylguanidine derivatives of the formula I in which R 1 , R 2 , R 4 , Ar, X and n have the meanings indicated in the claims, their physiologically tolerable...
6333198 Compound and its use  
A method of testing the purity or stability to degradation of a sample of lamotrigine or a pharmaceutical dosage form comprising lamotrigine comprises assaying the said sample for the presence of a...
6328981 Composition comprising a dibenzoylmethane derivative and a polyamino polymer  
Cosmetic and/or dermatalogoical compositions comprising, in a cosmetically and/or dermatologically acceptable vehicle, i) a dibenzoylmethane derivative, in particular...
6329373 Metalloproteinase inhibitors  
A compound of formula (I) ##STR1## wherein X is a --CONHOH group and the R groups are defined in the claims. The compounds are inhibitors of matrix metalloproteinases involved in tissue degradation...
6316447 Pesticidal composition  
There are described a pesticidal composition which comprises, in variable quantities, the pesticidally active compound of the formula ##STR1## in free form or in the form of an agrochemically...
6303603 3-oxo-2(H)-1,2,4-triazine derivatives as ligands of 5 HT1A receptors  
The invention concerns novel 3-oxo-(2H)-1,2,4-triazine derivatives of general formula (I) in which R 1 represents: hydrogen, when A is an optionally substituted nitrogen atom; a linear or branched...
6294549 Method for eliciting an αvβ5 or dual αvβ3/αvβ5 antagonizing effect  
A method for eliciting an α v β 5 or dual α v β 3 /α v β 5 antagonizing effect in a mammal which comprises administering to the mammal a therapeutically effective amount of a compound of...
6294536 Triazine derivatives, their production and use  
The present invention relates to compounds represented by the formula: ##STR1## wherein ring H represents an optionally substituted aromatic heterocyclic group or an optionally substituted...
6288065 Quinoxaline-carboxylic acid derivatives  
The disclosure relates to quinoxaline derivates of Formula I ##STR1## wherein R 1 , R 4 , R 5 , R 6 , R 7 and R 8 are defined in the disclosure, as well as their production and use in...
6277847 Herbicidal isoindolinonyl-and 3,4-dihydroisoquinolonyl-substituted heterocycles  
This invention relates to herbicidal compounds of formula (I), methods of making such herbicidal compounds and methods of using such herbicidal compounds. It has been found that compounds of...
6274580 Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus  
Compounds selected from the group consisting of formulae I, II, III, IV, VI, VII, and VIII ##STR1## wherein R is H or NH 2 , and pharmacologically acceptable salts thereof, are suitable for use in...
6245361 Tuberculocidal synergistic disinfectant compositions and methods of disinfecting  
An aqueous cleaning and disinfecting composition is disclosed that is a synergistic combination of (a) a sufficient amount of a chlorine-containing bleach compound such as sodium hypochlorite or...
6235738 Diphenyl-substituted heterocycles with 6-membered ring, processes for the preparation thereof and the use thereof as medicaments  
The invention relates to novel diphenyl-substituted heterocycles with 6-membered ring of general formula (I) ##STR1## in which A, X and the residues R 1 , R 2 , R 3 , R 4 and R 5 are as defined...
6221886 Thio acid derived monocyclic N-heterocyclics as anticoagulants  
This invention is directed to monocyclic N-heterocyclics which are substituted by acyclic or cyclic thio derivatives which are useful as anti-coagulants. This invention is also directed to...
6218391 Triazinones and derivatives thereof  
Corticotropin releasing factor (CRF) antagonists of Formula (I) ##STR1## and their use in treating psychiatric disorders and neurological diseases including major depression, anxiety-related...
6218410 Medicines comprising Rho kinase inhibitor  
A Rho kinase inhibitor is provided as a novel pharmaceutical agent, particularly as a therapeutic agent of hypertension, a therapeutic agent of angina pectoris, a suppressive agent of...
6211178 Triazine derivative, production and use thereof  
The present invention provides a novel triazine derivative of the formula ##STR1## wherein ring A is an optionally substituted aromatic group which be; X is an oxygen or sulfur atom; R 1 and...
6200984 Naphtho-imidazo pyridine derivatives useful in treating central nervous system disorders  
A compound of the general formula I: ##STR1## is disclosed as useful in treating disorders of the central nervous system. Pharmaceutical compositions, processes for preparing the compounds and...
6197766 Insecticidal dihydrooxadiazine compounds  
Insecticidal dihydrooxadiazine compounds having the formula: ##STR1## wherein X is O, N or S; R is a substituted or unsubstituted phenyl or C 4 -C 5 heterocyclic group; R 2 , R 3 , R 4 ,...
6197769 Indazole amide compounds as serotoninergic agents  
A compound having general formula (I) wherein R 1 , R 2 , R' 3 , R 4 , and R 6 have the meanings stated in the description, acid addition salts thereof with pharmaceutically acceptable organic and...
6194408 Triazineone compounds for treating diseases due to Sarcocystis, Neospora and Toxoplasma  
Disclosed herein are a methods of treating therapeutically, or metaphylactically infected animals susceptible to, or infected animal suffering from parasitic neurologic or abortigenic diseases due...
6191130 Cyclohexane derivatives difunctionalised in 1,4 as ligands of 5T H1A receptors  
The invention concerns novel cyclohexane derivatives difunctionalised in 1.4 of general formula (1) in which A represents a group such as (IIa) in which Ar itself represents an aromatic structure...
6159980 Pyrazinones and triazinones and their derivatives thereof  
Corticotropin releasing factor (CRF) antagonists of Formula (I) ##STR1## and their use in treating psychiatric disorders and neurological diseases including major depression, anxiety-related...
6159974 LDL receptor gene expression promoters  
6100252 Heterocyclic compounds and their use as angiotensin antagonists  
6090370 Use of selected benzotriazole and triazine derivatives for protecting human hair from the harmful effects of UV radiation  
Benzotriazole derivatives of formula ##STR1## or triazines of formula ##STR2## wherein R is hydrogen or chloro; R 1 is C 1 -C 12 alkyl or phenyl-C 1 -C 3 alkyl; R 2 is C 1 -C 4 alkyl or SO...
6090801 Pharmaceutical compositions containing ceftriaxone and penems  
6083959 Quinoline derivatives, processes for their preparation and their use as medicaments  
A compound of the formula: ##STR1## wherein R 1 is lower alkyl, R 2 is hydrogen, lower alkyl or a heterocyclic group, R 3 is hydrogen, lower alkyl or halogen, R 4 is lower alkyl or...
6080738 Heterocyclic amide compounds and medicinal uses thereof  
A heterocyclic amide compound of the formula (I) ##STR1## wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition thereof...
6075023 Method for combatting fish mycoses and one-celled ectoparasites  
6071913 Angiotensin II receptor antagonistic 1,2,4-triazin-5-one derivatives  
Disclosed are novel 1,2,4-triazin-5-one biphenyl derivatives having structural formula (I) useful as non-peptide antagonists of angiotensin II receptor: ##STR1## where R 1 represents alkyl,...
6060469 Spiro-piperidine derivatives and their use as tachykinin antagonists  
The present invention relates to compounds of formula (I), ##STR1## wherein R 1 represents halogen, hydroxy, C 1 -6 alkyl group optionally substituted by one or three fluorine atoms, C 1 -6 alkoxy...
6060470 Triazine compounds and methods of use therefor  
The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises a substituted...
6057319 3,4-Diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors  
The invention encompasses the novel compound of formula (I) useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions for...
6048542 Inhibiting growth of microorganisms in water-based pesticide suspensions  
The present invention provides a composition for inhibiting the growth of microorganisms in water-based pesticide suspensions. In accordance with this invention, the composition comprises from...
6046195 Spiro-azacyclic derivatives, their preparation and their use as tachykinin antagonists  
6043242 Imidazopyridazines  
Compounds of formula (I) ##STR1## in which the substituents and symbols have the meanings indicated in the description, are suitable for controlling Helicobacter bacteria.
6034083 Pyridine derivatives as pesticides  
Compounds of formula ##STR1## wherein n and Z are as defined in claim 1, and, where appropriate, tautomers thereof, in each case in free form or in salt form, can be used as agrochemical active...
6011034 Insecticidal dihydrooxadiazine compounds  
Insecticidal dihydrooxadiazine compounds having the formula: ##STR1## wherein X is O or S; R is a substituted or unsubstituted phenyl or heterocyclic group; R 1 is halogen, haloalkyl or...
6008219 Bicyclic amine derivatives and their use as anti-psychotic agents  
This invention relates to compounds of formula (I) ##STR1## which are useful as modulators of D 3 receptors, in particular as antipsychotic agents.
5994355 1, 2, 4-Triazin-3-one derivatives, production and use thereof  
The present invention provides a novel triazine derivative of the formula ##STR1## wherein ring A is an optionally substituted aromatic group; X is an oxygen or sulfur atom; R 1 and R 6 are...
5985875 1,2,4-triazine-3, 5-dione derivatives, their production and use thereof  
The present invention relates to compounds represented by the formula: ##STR1## wherein R 1 is (1) an optionally substituted alkyl group which may be bonded through a hetero atom, (2) an...
5977106 3,5-dioxo-(2H,4H)-1,2,4-triazine derivatives  
Novel 3,5-dioxo-(2H,4H-triazine derivatives of general formula (I): wherein R 1 is hydrogen, a C 1 -C 4 alkyl radical, phenyl C 1 -C 4 alkyl or phenyl, the phenyl ring being optionally...
5962460 Antineoplastic α-methylene-γ-butyrolactones  
The present invention provides antineoplastic α-methylene-γ-butyrolactones represented by the general formula I! wherein R 1 is a phenyl group optionally substituted with one or two groups...
5958922 Insecticidal mixtures  
This invention pertains to synergistic insecticidal mixtures of methyl 7-chloro-2,5-dihydro-2- (methoxycarbonyl) 4-(trifluoromethoxy)phenyl!amin o!carbonyl!indeno 1,2-e! 1,3,...
5948781 Adamantyl substituted oxindoles as pharmaceutical agents  
This invention relates to a method of treating cancer by administering a compound of the formula wherein R 1 , R 2 , R 3 , R 4 , R 5 , E 1 , E 2 , p, Het' and Het" are defined as indicated in the...
5942510 Pharmaceutical composition containing lamotrigine  
A lyophilized formulation of lamotrigine having been prepared by lyophilizing a frozen sterile aqueous solution of Imotrigine mesylate in which the pH is from 2.4 to 4.
5942532 2-substituted phenyl-benzimidazole antibacterial agents  
The invention relates to benzimidazole antibacterial compounds of the Formula I: ##STR1## as described herein, pharmaceutical compositions containing the compounds, and methods for their production...
5922709 Antifungal composition  
An antifungal composition, containing a synergistic mixture, containing the compound of the formula (I): ##STR1## wherein R is acetyl or lower alkyl; or a pharmaceutically acceptable salt thereof;...
5912243 (4,4-difluorobut-3-enylthio)-substituted heterocyclic or carbocyclic ring compounds having pesticidal activity  
A compound having the formula R--S(O) n CH 2 CH 2 CHCF 2 , or a salt thereof, wherein R is a phenyl group or a heterocyclic group selected from furyl, thienyl, isoxazolyl, isothiazolyl,...
Matches 101 - 150 out of 340 < 1 2 3 4 5 6 7 >