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8178498 |
Medicament and method of treating an organism with medicaments
A medicinal composition includes an active medicinal substance in therapeutic dose and a potentiated medicinal preparation produced from the substance by homeopathis methods.
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8129362 |
Combination/association of adapalene and benzoyl peroxide for treating acne lesions
Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or...
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8080537 |
Combinations of adapalene and benzoyl peroxide for treating acne lesions
Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination...
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8071644 |
Combinations of adapalene and benzoyl peroxide for treating acne lesions
Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination...
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7989422 |
Antibacterial agents
The present invention, in one aspect, provides a method of inhibiting bacterial growth by contacting bacteria with an effective amount of at least one monosaccharide compound of formula (1) as...
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7960353 |
Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders.
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7943586 |
Antineoplastic agents targeted via glut transporters
The present invention relates to novel antineoplastic agents and cancer diagnostic agents that specifically target neo-plastic cells via the GLUT transportation system. More specifically, the...
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7923434 |
Phosphole derivatives complexed with metals, and pharmaceutical uses thereof
The invention concerns pharmaceutical compositions comprising as active compound at least one compound of general formula (A), wherein: M represents a metal atom, and their uses in particular for...
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7879808 |
Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient
An objective of the present invention is to provide compounds of formula (1) or their pharmacologically acceptable salts or solvates wherein A represents aryl; R1 represents N-optionally...
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7871982 |
Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient
This invention provides compounds of formula (I) or its pharmacologically acceptable salt or solvate, wherein A represents aryl or a monocyclic or bicyclic heterocyclic group, R1 represents a...
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7867980 |
Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient
An objective of the present invention is to provide compounds of formula (I) or their pharmacologically acceptable salts or solvates wherein A represents aryl while R1 represents a five- or...
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7862804 |
Admistration of C-glycoside compounds for depigmenting/whitening the skin
C-glycoside compounds having the formula (I): are useful for depigmenting/whitening the skin and/or for the anti-browning thereof.
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7851450 |
Gangliosides with a modified acyl function
The invention relates to a ganglioside mixture, consisting of gangliosides, of the following general formula: (sugar)-OCH2—CH(—NH—CO—R1)—CH(OH)—CH═CH—R2, wherein (sugar) represents a sugar radical...
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7829542 |
Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for...
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7811998 |
Novobiocin analogues as anticancer agents
Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present...
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7732414 |
C-glycoside compounds for stimulating the synthesis of glycosaminoglycans
C-glycoside compounds are suited for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue, advantageously hyaluronic acid, and/or...
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7622451 |
Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders.
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7608594 |
Novobiocin analogues as anticancer agents
Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present...
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7553819 |
Multivalent inhibitors of serum amyloid P component
Novel glycerol cyclic pyruvate derivates were prepared and demonstrated to inhibit the binding of an immobilized D-proline derivative to serum amyloid P component (SAP) have been prepared. As such,...
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7524510 |
Alkyl-glycoside enhanced vaccination
Described herein are methods for the noninvasive immunization of a subject that involve alkyl glycosides. Also described herein are compositions, kits, and devices for the noninvasive immunization...
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7514411 |
Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure wherein R1, R2, R3, R4, R5, R6, R7, W, Y, and Z are defined herein; or a pharmaceutically...
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7501399 |
Immunoeffector compounds
This invention provides compounds containing a 2-deoxy-2-amino-β-D-glucopyranose (glucosamine) glycosidically linked to an cyclic aminoalkyl (aglycon) group. The invention further provides methods ...
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7439232 |
Heteroaryl 5-thio-β-D-glucopyranoside derivatives and therapeutic agents for diabetes containing the same
There is provided a heteroaryl 5-thio-β-D-glucopyranoside compound of the following formula, which has an inhibitory effect on SGLT2 activity, or a pharmaceutically acceptable salt thereof or a ...
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7390785 |
τ-conotoxin peptides
The invention relates to relatively short peptides (termed τ-conotoxins herein), about 10-25 residues in length, which are naturally available in minute amounts in the venom of the cone snails or ...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7223737 |
Method of treating dry eye disorders using glycosides
The topical use of glycosides for the treatment of dry eye disorders is disclosed.
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7199106 |
Lincomycin derivatives possessing antimicrobial activity
Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria,...
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7183261 |
Galactosylceramide analogs, and β-glucocerebrosidase activators, external skin preparations and method of activating β-glucocerebrosidase using the analogs
Galactosylceramide analogues represented by the following formula (1) or (2). (wherein X and Y each represent S or O, R1 and R2 each represent an alkyl group or an alkenyl group each having 9 to 35...
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7179794 |
Multivalent macrolide antibiotics
Disclosed are multibinding compounds which include macrolide antibiotics, aminoglycosides, lincosamides, oxazolidinones, streptoramins, tetracycline and/or other compounds which bind to bacterial...
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7157078 |
Devices and methods for eliminating termite colonies
This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing a) a termiticide selected such...
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7153877 |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and...
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7153826 |
Treatment of rosacea
Cyclic peptide antibiotics including the loloatins are effective in the treatment of rosacea, particularly when administered in conjunction with an antibiotic such as metronidazole that is...
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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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7060732 |
Antibiotic/benzoyl peroxide dispenser
Two separate compositions, one containing an effective anti-acne treating amount of a first active ingredient and one containing a second active ingredient that is incompatible with the first...
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7056702 |
Detecting lipocalin
The invention provides antibodies reactive with distinct lipocalin epitopes that are useful for detecting inflammation and bacterial infections in mammals.
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7029671 |
Method for activating human antigen-presenting cells, activated human antigen-presenting cells, and use thereof
The invention relates to a method for activating human-derived antigen-presenting cells by in vitro cultivation with at least one of the glycoside compounds represented by formula (A) or salts...
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7026301 |
Method of orally treating inflammatory skin conditions with prodrugs of 5-fluorouracil
The present invention relates to the treatment of inflammatory skin conditions, including psoriasis, with a prodrug of 5-fluorouracil. The invention relates to methods for treatment of psoriasis...
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6979675 |
Treatment of cancer with 2-deoxyglucose
The compound 2-deoxyglucose can be used to treat cancer and to improve patient outcome when administered at a therapeutically effective dose, and, optionally, co-administered with other anti-cancer...
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6911434 |
Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for...
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6908903 |
Cluster clearing agents
Cluster clearing agents (CCAs) and the use thereof are discussed. CCAs are composed of a hepatic clearance directing moiety which directs the biodistribution of a CCA-containing construct to...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6800613 |
Prophylactic and therapeutic treatment of infectious and other diseases with mono- and disaccharide-based compounds
Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ mono- and...
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6793921 |
Specific antibodies for use in preparation of pharmaceutical compositions useful in the prevention or treatment of gastritis, gastric ulcers and duodenal ulcers
The present invention provides specific antibodies obtained from eggs laid by hens which have been immunized against urease of Helicobacter pylori as an antigen, and specific antibodies obtained...
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6794370 |
Method for treating cancer using camptothecin derivatives and 5-fluorouracil
A combination therapy for treating cancer including administering at least one camptothecin derivative in conjunction with another anticancer agent. The combination therapy is preferably used as a...
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6787525 |
Glyceryl nucleotides, method for the production thereof and their use
The invention relates to glyceryl nucleotides of the formula Ia in whicha) one of the radicals A1, A2 and A3 is a hydrogen atom or a radical selected from hydroxyl, mercapto, alkyl, alkenyl,...
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6777004 |
Composition containing novel compound corniculatonin having antifungi properties and a process for preparing the same
The invention relates to a novel compound oleanane triterpenoid oligoglycoside of formula 1 of the accompanying drawing (trivially called corniculatonin), the invention also relates to a process...
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6713074 |
Cosmetic composition and method
The cosmetic topical formulation of this invention is directed toward diminishing skin wrinkling, fine line, improving skin tone, and combinations thereof. Preferably, the topical formulation...
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6673357 |
Alkaloid glycoside for use as a medicament
The invention concerns an alkaloid glycoside for use in medicine. In a preferred aspect, the alkaloid glycoside is used for the stimulation of a class I-restricted immune response and/or a class...
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6670330 |
Cancer chemotherapy with 2-deoxy-D-glucose
A class of glycolytic inhibitors is useful in the treatment of solid tumors by attacking anaerobic cells at the center on the tumor. 2-deoxyglucose, oxamate and various analogs thereof are...
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6663886 |
Inhibition of cell-cell binding by lipid assemblies
This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides...
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