Matches 101 - 150 out of 178 < 1 2 3 4 >
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4661505 Leukotriene antagonists  
This invention provides novel alkane derivatives which are leukotriene antagonists, formulations of those derivatives, and a method of using those derivatives for the treatment of conditions...
4609656 Medical agent for improving and treating mental symptoms induced by cerebral disturbances  
A medical agent for improving and treating mental symptoms induced by cerebral disturbances comprising a composition containing 2-(7-indenyloxymethyl)morpholine (generic name: indeloxazine) or an...
4605673 7H-dibenzo(a,c,)cyclohepten-5-one-(7) derivatives  
The invention is concerned with 7H-dibenzo(a,c)-cyclohepten-5-one-(7) derivatives of general formula I ##STR1## wherein R 1 and R 2 can be the same or different, a hydrogen atom, an alkyl radical...
4605654 2-(arylalkyloxymethyl)morpholines and the central nervous system compositions  
The present invention relates to new 2-(arylalkyloxymethyl)morpholine derivatives, the preparation thereof and their application as drugs which are useful in the treatment of disorders of the...
4598077 Amidine derivatives and cardiotonic compositions  
Amidine derivatives of the formula ##STR1## wherein R 1 and R 2 , which may be the same or different, represent each a hydrogen atom or a lower alkyl group, or R 1 and R 2 together with an...
4562211 Pharmaceutically active 2-substituted-1-(omega-aminoalkoxy)benzenes  
2-Substituted-1-(omega-aminoalkoxy)benzenes are prepared and found useful as pharmaceutical agents, particularly as antidepressants.
4543353 Ester and amide derivatives of 13,14-didehydro prostaglandins  
Esters of 13,14-didehydro prostaglandins have been prepared.
4514396 15-Cycloaliphatic derivatives of 13,14-didehydro-carboprostacyclins and process for their preparation  
13, 14 didehydro-15 cyclic prostacyclins have been prepared.
4495184 Morpholino propanol derivatives, fungicidal compositions and use  
A 1-phenyl-3-amino-propane derivative of the formula ##STR1## in which R 1 and R 2 independently represent alkyl radicals or R 1 and R 2 together with the nitrogen atom to which they are bonded...
4486428 Bicyclic benzo fused compounds  
Bicyclic fused benzenoid compounds of the formula ##STR1## and pharmaceutically acceptable cationic and acid addition salts thereof, where M is O, CH 2 or NR 6 ; R 6 is hydrogen, formyl,...
4479950 Aroylaminoacid disulfides  
Compounds of the structure ##STR1## wherein: P and Q are independently hydrogen, halo, CF 3 , OR 1 , SR 1 , sulfamoyl, alkyl and NR 1 R 2 ; R 1 , and R 2 are independently hydrogen, alkyl,...
4430332 Ethers of 1-(2-propynyloxy)-2-amino-3-propanol  
The invention is dealing with compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, in which R 1 and R 2 each represent a lower alkyl radical or a phenyl radical, or,...
4424202 Azelaaldehydates as psychotropic agents  
A method for producing a psychotropic response, especially for alleviating the symptoms of alcohol withdrawal, comprises administering to a human or animal subject in need thereof a...
4421927 New cinnamoyl-cinnamic acid derivative, and its use as pharmaceutical  
The present invention relates to a new cinnamoyl-cinnamic acid derivative selected from the group constituted by: (i) the m-cinnamoyl-cinnamic acid derivatives of formula ##STR1## in which: X o...
4393061 Anesthetic-antipruritic morpholine compounds, compositions and use  
N-[3-(4-{3-Fluorobenzyloxy}phenoxy)propyl]morpholine and its pharmaceutically acceptable salts possess topical anesthetic-antipruritic properties. The free base can be obtained by coupling an...
4391827 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor  
Cycloalkanones, cycloalkanols and unsaturated analogs thereof, each of which has at the 3-position a 2-hydroxy-4-substituted phenyl group wherein the 4-position substituent is alkyl which can have...
4390537 1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, compositions and use  
1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, a class of compounds possessing anti-allergic properties for use in the treatment of allergic conditions, such as asthma prepared by...
4386086 Method for controlling ectoparasitic Acarina  
A method of controlling ectoparasitic Acarina that bore into and through the dermal integument of warm blooded animals by orally administering an 2-aryl-1,3-indandione and derivatives to said...
4342762 Basic ethers and pharmaceutical compositions containing the same  
The invention relates to novel basic ethers of the general formula /I/ and pharmaceutically acceptable acid addition salts and quaternary salts thereof, ##STR1## wherein R 1 and R 2 may be the...
4323568 Pharmaceutically active (omega-aminoalkoxy)bibenzyls  
(Omega-aminoalkoxy)bibenzyls are prepared and found useful as pharmaceutical agents, particularly as inhibitors of platelet aggregation.
4318923 Benzaminoethylphenoxycyclohexylacetic acid derivatives  
Benzaminoethylphenoxycyclohexylacetic acid derivatives having the formula ##STR1## wherein R 1 represents hydrogen atom, a halogen atom, hydroxyl group, a lower alkyl group or a lower alkoxy...
4297356 Memory enhancer containing 2-(7-indenyloxymethyl-morpholine  
A memory enhancer comprising a composition containing 2-(7-indenyloxymethyl)-morpholine or an acid addition salt thereof as the effective component.
4278674 Substituted 14-desoxy-mutilin compositions  
This invention relates to new pleuromutilins of the formula: ##STR1## wherein either R 1 is ethyl or vinyl, n is an integer from 2 to 5, x is sulphur, a group ##STR2## or a group N--R...
4277471 1,1-Biphenyl-2-yl alkylamines, formulations and antiarrhythmic treatment  
Biphenylylalkylamines which have anti-arrhythmic activity have been prepared. Pharmaceutical formulations containing such compounds and a method of treating cardiac arrhythmias are provided.
4271160 Substituted morpholine derivatives and pharmaceutical compositions  
Substituted morpholine derivatives, such as, for instance the compound 2-[α-(3,4-methylendioxy-phenoxy)-benzyl]-morpholine are disclosed. The claimed compounds are active on the central nervous...
4256745 New prostane derivatives and process for their preparation  
Prostan-1-ol esters and intermediates for their preparation are described; the former compounds exhibit improved organ specificity and a longer duration of activity at lower dosages than the...
4252804 Therapeutically useful 3,4,5-trimethoxybenzene derivatives  
Compounds of the formula I ##STR1## wherein m and n are 0, 1 or 2, X represents oxygen, imino, benzylimino, or morpholinoethylimino, Y represents CO, CONH, COO or SO 2 , and NR 1 R 2 represents a...
4241059 6-[(Aryloxy)methyl]-2-morpholinemethanol derivatives and use thereof  
6-[(Aryloxy)methyl]-2-morpholinemethanol derivatives are provided having the structure ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, or lower alkenyl, and Ar represents a...
4235896 Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same  
Compounds of the formula ##STR1## in which A is lower alkyl, or a substituted or unsubstituted phenyl, thienyl, furyl, indolyl or thiaindolyl radical, R, X 4 and X 5 are hydrogen or lower alkyl,...
4234602 Naphthalenone derivatives and analogs  
Compounds having the formula ##STR1## wherein R 1 is hydrogen, alkyl or aryl; R 2 is alkylamino, dialkylamino, or a nitrogen containing heterocyclic group; R 3 is hydrogen, halogen, alkyl,...
4233298 Esters of p-carbonylphenoxy-isobutyric acids  
This invention is concerned with esters of p-carbonylphenoxy-isobutyric acids of the general formulae: ##STR1## wherein R is a phenyl group substituted by one or two halogen atoms; R' is H, CH 3...
4229449 Substituted morpholine derivatives and compositions  
Substituted morpholine derivatives, such as, for instance, the compound 2-[α-(2-methoxy-phenoxy)-benzyl]-morpholine are disclosed. The claimed compounds are active on the central nervous system,...
4191765 1-Aryloxy-2-hydroxy-3-aminopropanes  
Compounds of formula I ##STR1## wherein R 1 and R 1 ' are identical or different and represent hydrogen, an alkyl radical or alkoxy radical having 1-4 carbon atoms, the allyl group, a halogen atom...
4183927 Substituted phenylthioalkylamines and compositions thereof  
Novel substituted phenylthioalkylamines, salts and pharmaceutical compositions thereof wherein the sulfur may appear as a sulfide, sulfinyl or sulfonyl are disclosed as antithrombotic agents.
4182761 Acyloxy-substituted aryloxyalkyl diketones  
Acyloxy-substituted aryloxyalkyl diketones, useful as anti-viral agents, are prepared either by esterification of the corresponding hydroxy-substituted compounds or by reacting a haloalkyl diketone...
4156723 Perhydro naphthalene pentol derivatives  
Compounds are provided having the structure ##STR1## wherein R 1 , R 2 , R 3 or R 4 is hydrogen or acyl, and R 5 is hydrogen or acyl, X is a straight or branched bivalent alkylene radical and Y...
4155907 Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines  
A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a...
4140770 Benzoylethers and processes for their production  
Processes for preparing benzoylethers, their acid additive salts and their quaternary ammonium salts are disclosed. These compounds have useful pharmacodynamic properties.
4104380 Dibenzyl glycolic acid derivatives  
The present invention is concerned with new dibenzylglycolic acid derivatives and with the preparation thereof. These derivatives show an extraordinary anti-hypertensive and antisecretory profile.
4098889 Antithrombotic 2-(aminoalkylthio)-N,N'-p-phenylenebissulfonamides  
Novel antithrombotic 2-(aminoalkylthio)-N,N'-p-phenylenebissulfonamides, a method for inhibiting blood platelet aggregation, and pharmaceutical compositions.
4082851 Sulphonamides, compositions containing the same and methods for using the same in the treatment of hypertension or odemeas  
The invention relates to a series of new compounds, salts thereof and to methods for the preparation of the compounds which have the general formula ##STR1## in which R 1 stands for an...
4069326 Morpholino containing indane acetic acid esters  
The present invention relates to certain indane derivatives of general formula ##STR1## in which: X represents a hydrogen or halogen atom; R 1 and R 2 , which may be identical or different, each...
4065584 Sulphur containing arylamine derivatives  
The invention provides new compounds of the formula: Ar--SO Y --Alk--NR 1 R 2 in which Ar represents a phenyl group, a phenyl group substituted by one or more C 1 -C 4 alkyl, CF 3 and COOH...
4061733 Veterinary compositions for inducing estrus in animals and method  
Novel veterinary compositions for inducing estrus in animals comprising an effective amount of a homogeneous mixture of non-toxic, veterinary acceptable acid addition salts of cis-clomiphene and...
4060609 Biphenylyl ethers and method of use  
Biphenylyl ethers of the formula R--O--CH 2 --CR 1 (OH)--CH 2 Z wherein R 1 is H or CH 3 ; Z is dialkylamino of 2-8 carbon atoms, morpholino, pyrrolidino, piperidino, homopiperidino,...
4060612 Pharmaceutically active 2-omega-aminoalkoxydiphenyl sulfides  
2-Omega-aminoalkoxydiphenyl sulfides are prepared and found useful as pharmaceutical agents, particularly as antidepressants.
4053596 Indanpentol derivatives  
Compounds are provided having the structure ##STR1## wherein n is 1, 2 or 3, m is 0, 1 or 2, R 1 , R 2 , R 3 , R 4 and R 5 may be the same or different and can be hydrogen, lower alkyl,...
4027037 N-substituted β-aminocrotonic acid esters  
N-substituted β-aminocrotonic acid esters of the formula ##STR1## in which R 1 is hydrogen, or alkyl or alkenyl with up to 4 carbon atoms; R 2 is straight-chain or branched alkyl or alkenyl...
3995036 Methods of treating a mammal afflicted with excessive histamine with dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzene and salts thereof  
Excessive histamine in mammals is effectively relieved by the administration of dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzenes. The compounds are relatively non-toxic in dosages required...
3995037 Methods of treating a mammal afflicted with pain with dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzene and salts thereof  
Pain in mammals is effectively relieved by the administration of dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzenes. The compounds are relatively non-toxic in dosages required to alleviate...
Matches 101 - 150 out of 178 < 1 2 3 4 >