Matches 151 - 200 out of 277 < 1 2 3 4 5 6 >
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5021414 Phenol derivatives  
A phenol derivative of the formula NU--A--X--R 1 wherein NU is a defined bis-phenolic nucleus including a hydroxyphenyl-hydroxynaphthyl; hydroxyphenyl-hydroxyindanyl,...
5017619 Phenethanolamine derivatives  
The invention is directed to phenethanolamine derivatives and their pharmaceutically compatible salts, having the formula ##STR1## wherein n is the number 1 or 2; L 1 and L 2 are hydrogen, C 1 -3...
4990505 Phenethanolamine compounds  
The invention provides compounds of the general formula (I) ##STR1## wherein the substituents are defined in the specification, and physiologically acceptable salts and solvates thereof. The...
4977153 3-aminopropyloxyphenyl derivatives, pharmaceutical compositions containing them and method for the therapy of diseases  
Compounds of formula (I), ##STR1## characterized in that R signifies optionally substituted heteroaryl-, heteroarylakyl or heteroarylalkenyl, R 1 signifies hydrogen or a substituent, R 2 is...
4977148 Amide derivatives  
The invention concerns novel phenoxyacetic acid amide derivatives of the formula I (and pharmaceutically acceptable salts thereof) in which R 1 is hydrogen or fluoro, R 2 is phenyl, cycloalkyl,...
4975464 Treatment of diseases caused by abnormal action of elastase  
Compounds presented by the general formula: ##STR1## wherein Y is oxygen, R 2 is H, alkyl, alkoxy, alkoxymethyl, --COOR 3 , --CH 2 COOR 3 , --CHCH--COOR 3 , halogen, --CF 3 , --COR 4 , --OCOR...
4962107 Agent for cerebral protection  
Compounds of the general formula ##STR1## wherein: X is halogen or trifluoromethyl; R 1 is hydrogen, halogen or trifluoromethyl; R 2 is hydrogen methyl or hydroxymethyl; R 3 is hydrogen...
4959364 Method of treating inflammation, allergy, asthma and proliferative skin disease using heterocyclic amides  
The compounds of this invention are heterocyclic amides represented by the formula: ##STR1## wherein: R 1 R 2 are the same or different members of the group consisting of halo, phenyl,...
4959365 Topical compositions of lipophilic pharmaceuticals agents  
Improved pharmaceutical compositions for the topical administration of a lipophilic, pharmaceutical agent to a human or lower animal subject comprising a safe and effective amount of a...
4950669 Methods and compositions for promoting growth of animals  
The growth rate of an animal is stimulated by administering to the animal a growth promoting amount of a compound of the formula ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 , which can be the...
4948807 Phenyl carbamates  
Phenyl carbamates of the general formula ##STR1## wherein R 1 to R 5 are as defined in the claims, are useful as pharmaceuticals.
4935422 Acyloxypropanolamines  
Compounds of the present invention, are represented by the general formula ##STR1## wherein R represents a straight or branched loweralkyl from 1 to about 6 carbon atoms, loweralkene from 2 to...
4935421 2-hydroxypropylamine aryl ester derivatives and pharmaceutical use  
Novel compounds of the general formula ##STR1## wherein Ar represents a substituted or unsubstituted aromatic or heterocyclic group; W represents alkylene of from 1 to about 10 carbon atoms; and B...
4933340 Method for the treatment of obesity  
The invention concerns the use of N-(2-[RS-2-hydroxy-3-(4-hydroxyphenoxy)propylamino]ethyl)-mo rpholinoformam ide or a salt thereof in the production of a medicament for the treatment of obesity...
4933367 Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds  
This invention relates to carboxylic acid derivatives and their use thereof. The compounds are useful in treatment of various diseases such as diabetes, prediabetic conditions, adipositas ailments...
4929635 New derivatives of 4-vinyl benzoic acid, process for their preparation and their uses in therapeutics and as ligands  
The invention relates to compounds of the formula ##STR1## These compounds may be used in therapeutics for the treatment of acne, psoriasis, disorders of keratinization, in certain forms of cancer...
4927835 Acylphenol derivatives, useful as anti-inflammatory agents and pain suppressants  
Compounds of the formula (I): ##STR1## or a pharmaceutically acceptable salt thereof, wherein: R 1 is cycloalkyl of 5 to 7 carbon atoms; aryl of 6 to 10 carbon atoms unsubstituted or substituted...
4927823 Fungicides  
The invention relates to synergistic mixtures comprising as active ingredients (a) a compound of formula I ##STR1## wherein R 1 and R 2 are both H or together form a covalent bond, R 3 is...
4923863 Morpholine derivatives, pharmaceutical compositions and use  
Compounds are disclosed of formula (I): ##STR1## wherein R 1 and R 2 are the same or different and are C 1 -6 alkyl or C 3 -6 alkenyl; or --NR 1 R 2 forms a 5-membered (optionally containing an...
4916136 Eicosatetraynoic acid amides and their application in pharmacy  
Compound, characterized in that it corresponds to the formula: C 5 H 11 (C.tbd.C--CH 2 ) 4 --CH 2 CH 2 CO R (I) in which R is an amino group of structure ##STR1## in which R 1 and R 2 ,...
4910200 Acrylic acid morpholides, fungicidal compositions and use  
Compounds of the formula ##STR1## wherein A is ##STR2## B is ##STR3## R 1 is hydrogen; halogen, cyano or optionally substituted C 1 -4 alkyl; and Q is NR 8 R 9 or ##STR4## where R 2 to R 11 ...
4906662 Phenol derivatives, their preparation and the use thereof  
Disclosed are phenol derivatives of the formula ##STR1## wherein R 1 is a substituted phenyl group, R 2 and R 3 are C 1 -C 6 alkyl group and of the formula ##STR2## wherein R 8 , R 9 and R 10...
4898864 Bicyclic aromatic compounds, a process for their preparation and their use in cosmetics and human and veterinary medicine  
Bicyclic aromatic compound having the formula ##STR1## wherein R 1 , R 2 , R 3 and R 4 represent hydrogen or alkyl, at least two of R 1 -R 4 radicals being other than hydrogen, A represents...
4895842 Phenylalanine derivative and proteinase inhibitor  
A phenylalanine derivative having the formula (I): ##STR1## where R 1 and R 2 are independently hydrogen provided that both R 1 and R 2 are not hydrogen at the same time; C 1 -C 8 alkyl...
4889853 Hydroquinonlyphenyl butyric acid amide derivative  
A hydroquinonylphenyl butyric acid amide derivative having the formula (I): ##STR1## wherein R 1 represents an aromatic or heterocyclic group which may be substituted, R 2 represents a hydrogen...
4889849 Spasmolytically active tertiary amine derivatives  
The invention relates to new spasmolytically active tertiary amine derivatives and the salts thereof, of the formula (1) ##STR1## wherein the symbols have the following meanings: .circle.A is...
4880805 Use of alkylenediamine derivatives for the treatment of blood flow disturbances and pharmaceutical compositions containing them  
The present invention is concerned with the use of compounds of the general formula: ##STR1## wherein A is an optionally substituted phenyl or heteroaromatic radical, R 6 and R 7 are hydrogen or...
4877785 Non-peptidyl beta-succinamidoacyl aminodiols as anti-hypertensive agents  
Non-peptidyl compounds characterized generally as β-succinamidoacyl aminodios are useful as renin inhibitors for the treatment of hypertension.
4863923 Method of inhibiting superoxide release  
A method of inhibiting superoxide release and reducing tissue damage following an inflammatory or ischemic event employing benzothiophenes, benzofurans, and naphthalenes is disclosed.
4826841 Alkanoyl anilides as pesticides  
The present invention is in alkanoyl anilides exhibiting insecticidal and arachnicidal activity, wherein the alkanoyl is both branched and substantially or totally fluorinated.
4824842 Cinnamoyl piperidines and thiomorpholine and cerebral protection compositions  
Compounds of the general formula ##STR1## wherein: X is halogen or trifluoromethyl; R 1 is hydrogen, halogen or trifluoromethyl; R 2 is hydrogen, methyl or hydroxymethyl; R 3 is...
4818757 Ureidoalkanoylaminocarbonyl amino and imino acids and esters  
Compounds of the formula ##STR1## are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of...
4810725 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols, pharmaceutical compositions and use  
1-Aryloxy-3-(substituted aminoalkylamino)-2-propanols and pharmaceutically acceptable salts thereof have β-adrenergic blocking activity with some cardioselectivity and hence are useful as...
4797398 Morpholine compounds, compositions and use  
A compound of formula (I): ##STR1## or a salt thereof; where Z represents a heterocyclic ring and R 2 and R 3 are independently selected from hydrogen, nitrile, CONH 2 and SO 2 R 4 where R 4 ...
4788204 Pharmacologically active amides and pharmaceutical compositions containing them  
Amides of formula: ##STR1## in which A is ##STR2## V and W are H, halogen, alkyl (1-3C), alkoxy (1-3C), NO 2 or CF 3 , Z is bound in the ortho or para position with respect to B and is phenyl,...
4788199 Pharmacologically active amides, processes for their preparation and pharmaceutical compositions containing them  
Amides of formula: ##STR1## in which A is ##STR2## V and W are H, halogen, alkyl (1-3C), alkoxy (1-3C), NO 2 or CF 3 , Z is bound in the ortho or para position with respect to B and is phenyl,...
4774241 Derivative of benzoquinonylphenyl alkanoic acid amide  
A derivative of benzoquinonylphenyl alkanoic acid amide having the formula: ##STR1## wherein X represents an oxygen atom, sulfur atom, or methylated nitrogen atom, Me represents methyl, and n is 2...
4771061 Substituted piperazine-1,4-naphthalenediones useful for treating asthma, allergic diseases and/or inflammation  
This disclosure describes certain substituted piperazine-1,4-naphthalenediones useful as anti-asthmatic agents.
4766116 Diaryl butyric acid derivative and pharmaceutical use thereof  
A diaryl butyric acid derivative having the general formula: ##STR1## wherein R 1 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or an acyl group having 2 to 4 carbon...
4760061 Ether and ester derivatives of phenols  
Mono- or bis-complex esters or ethers of a phenol derivative of the formula NU--A--X--R 1 wherein NU is a defined mono- or bis-phenolic nucleus including a hydroxyphenyl-hydroxynaphthyl;...
4760057 (Acyloxyalkoxy)carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs  
This invention relates to novel (acyloxyalkoxy)carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs having a primary or secondary amine function...
4708954 Hypogylcemic oxaluric acid derivatives  
Pharmaceutical compositions containing an oxaluric acid derivative of the formula: ##STR1## wherein each of R 1 and R 2 , which may be the same or different, is hydrogen; an alkyl group or a...
4692446 Esters of aryloxypropanolamine derivatives and medicinal uses  
Novel compounds of the general formula ##STR1## wherein R 1 is lower alkyl, lower cycloalkyl, lower alkenyl, lower alkynyl, lower alkyl carboxymethyl, aryl carboxymethyl, aryl, or aralkyl; A is a...
4686220 Substituted 2-[b-substituted-amino)-ethylamino]-1,4-naphthalenediones for treating asthma, allergic diseases and inflammation in warm-blooded animals  
This disclosure describes certain substituted piperazine-1,4-naphthalenediones useful as anti-asthmatic agents.
4680307 Carbacyclin analogs  
A compound of the formula: ##STR1## wherein X 1 is a free or an esterified carboxyl group, or a group of the formula: ##STR2## (R a and R b are each independently a hydrogen atom, a C 1 -C 4 ...
4666906 Compounds for treating hypertension  
Compounds of the formula ##STR1## and their pharmaceutically acceptable salts, wherein the substituents are as defined herein, having antihypertensive activity.
4661505 Leukotriene antagonists  
This invention provides novel alkane derivatives which are leukotriene antagonists, formulations of those derivatives, and a method of using those derivatives for the treatment of conditions...
4661483 Antihypercholesterolemic lactone compounds, compositions and use  
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I)...
4639450 Polyprenylcarboxylic acid morpholides and pharmaceutical compositions  
This invention relates to polyprenylcarboxylic acid amides represented by the following general formula (I): ##STR1## wherein n is an integer of from 1 to 4, a and b stand for hydrogen atoms or a...
4639449 Morpholine containing propionylanilides and pharmaceutical compositions  
Propionylanilides, and relative salts of addition, having the following general formula: ##STR1## The new compounds are useful in the treatment of morbid cold-induced forms.
Matches 151 - 200 out of 277 < 1 2 3 4 5 6 >