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7618951 |
Use of prebiotics, preferably glucooligosaccharide, for the prevention of the onset of type II diabetes
The invention relates to the use of prebiotics for the preparation of food or pharmaceutical compositions which are intended for the treatment and/or prevention of hyperglycaemic syndromes and, in...
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7615536 |
1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound, and use thereof as a hypolipidaemic
The invention relates to the compound of the formula (A) and also to its physiologically acceptable salts. The compound is suitable as, for example, a hypolipidemic
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7601705 |
Polymer controlled induced viscosity fiber system and uses thereof
The present invention relates generally to a method of blunting the postprandial glycemic response in a human by feeding an induced viscosity fiber system. The invention also relates to an induced...
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7601370 |
Method for controlling body weight in estrogen-insufficient women
Disclosed are methods of controlling body weight in estrogen-insufficient women by administering compositions comprising (A) those dried fruit solids that inherently comprise flavonoids,...
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7601364 |
Carbohydrate mixtures
A carbohydrate mixture for dietetic foods and pharmaceuticals containing several carbohydrates is provided. The carbohydrate mixture comprises two different, substantially soluble carbohydrate...
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7598286 |
[(1H-indazol-3-yl)methyl]phenols and (hydroxyphenyl)(1H-indazol-3-yl)methanones
This invention provides anti-inflammatory agents of formula I, having the structure
wherein A and R 1 -R 10 are as defined in the specification, or a N-oxide thereof or a pharmaceutically...
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7592327 |
Asthma/allergy therapy that targets T-lymphocytes and/or eosinophils
A pharmaceutical composition for the treatment and/or prophylaxis of diseases caused by type I hypersensitivity reactions consisting essentially of Glicophosphopeptical, or pure Nigella Sativa ...
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7592306 |
Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
The present invention relates to methods of using lactoferrin (LF) to treat, prevent or reduce the incidence of organ transplant rejection and graft-versus-host-disease. More particularly, the...
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7589193 |
C-aryl glucoside SGLT2 inhibitors and method
A compound of the formula I
A method is also provided for treating diabetes and related diseases employing the above compound alone or in combination with another therapeutic agent.
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7585896 |
Composition for the prevention and treatment of kidney dysfunctions and diseases
A composition is disclosed which is suitable for the prevention and treatment of kidney dysfunctions and diseases and which can therefore take the form of a food supplement or of an actual...
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7585510 |
Vaccine
The invention relates to a vaccine for the treatment of disease caused by Neisseria , the vaccine including one or more immunogenic components for Neisseria serogroups, as well as antibodies to...
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7579449 |
Glucopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
Glucopyranosyl-substituted benzene derivatives of general formula I
where the groups R 1 to R 6 as well as R 7a , R 7b , R 7c are defined herein and the tautomers, the stereoisomers thereof,...
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7579389 |
Antimicrobial acrylic polymer
An antimicrobial additive composition is provided which economically and efficiently imparts antimicrobial characteristics to acrylic polymers, and particularly thermoformable acrylic sheets made...
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7576132 |
Arginine silicate inositol complex and use thereof
A method for preventing and treating a variety of disease states and disorders is provided, comprising the administration of an arginine silicate inositol complex to an individual in the presence...
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7572764 |
Uses of chemically-modified cholinesterases for detoxification of organophosporus compounds
A circulatory long-lived cholinesterase (ChE) protein, such as acetylcholinesterase (AChE) or butyrylcholinesterase (BChE), which is a ChE protein modified with a non-antigenic polymer. The ChE may...
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7569557 |
Compositions of estrogen-cyclodextrin complexes
Pharmaceutical compositions comprising low doses of sensitive complexes between an estrogen and a cyclodextrin are provided with improved stability. In specific embodiments the composition...
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7569540 |
Method for enhanced parenteral nutrition
A method for improved administration of nutrient is provide. The method includes co- or separate administration of a source of nutrients, especially carbohydrates, and insulinotropic peptides and...
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7566699 |
Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof
The present invention provides fused heterocyclic derivatives represented by the general formula:
wherein R 1 represents H, halogen, OH, etc.; R 2 represents H, halogen or an alkyl group; R 3...
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7566463 |
Oral rehydration compositions
An oral rehydration mixture (ORM) may include from 47 to 75 wt % of a glucose containing saccharide, from 6 to 13 wt % sodium chloride, from 6.5 to 19 wt % potassium chloride, from 2 to 5 wt %...
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7560443 |
Mixtures of fructose, sucrose and lactose as a low-calorie bulk sweetener with reduced glycemic index
Mixtures of fructose and lactose are useful for reducing caloric intake and glycemic index for individuals who are overweight, glucose-impaired, diabetic, or who just consume too large a fraction...
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7560434 |
AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
Compounds represented by the formula:
and pharmaceutically acceptable salts thereof and prodrugs thereof; wherein R 1 is H, CH 3 , C 2 H 5 , C 3 H 7 R 2 is H, CH 3 , C 2 H 5 , C 3 H 7 ,...
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RE40849 |
Method of treatment of glutathione deficient mammals
Glutathione (GSH) is a tripeptide of extreme importance as a catalyst, reductan, and reactant. It can be depleted intracellulary either by forming a direct complex with an electrophilic agent...
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7557089 |
Use of derivatives of succinate esters for the treatment of dementia
The use of extract form Wangla ( coeloglossum viride (L) Hartm. Var. Bracteatum (Willd.) Richter), succinate derivative esters, and a derivative and pharmaceutical acceptable salts thereof, for...
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7553819 |
Multivalent inhibitors of serum amyloid P component
Novel glycerol cyclic pyruvate derivates were prepared and demonstrated to inhibit the binding of an immobilized D-proline derivative to serum amyloid P component (SAP) have been prepared. As such,...
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7553817 |
Methods for improving cardiac function
The present invention relates to compositions for supplementing the diet of subjects suffering from cardiovascular or peripheral vascular disease or those at risk for such conditions. Ribose is...
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7553482 |
Use of a phosphate adsorbent to combat vascular diseases
The invention relates to the use of an adsorption material which has been modified with polynuclear metal oxide hydroxides for influencing the calcium level and, in particular, for treating or/and...
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7553479 |
Heat stable colloidal iron oxides coated with reduced carbohydrates and uses thereof
Compositions, methods of making the compositions, and methods of using the compositions are provided for an enhanced magnetic resonance imaging agent and a hematinic agent, the agents comprising...
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7544671 |
Stabilized hyaluronan preparations and related methods
Stabilized hyaluronan preparations wherein hyaluronan is combined with a polyglycol, such as polyethylene glycol. Stabilized hyaluronan preparations of this invention may maintain their viscosity...
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7544667 |
Hypocholesterolemic compounds
The present invention relates to novel hypocholesterolemic compounds of formula (I) useful in the treatment and prevention of atherosclerosis and for the reduction of cholesterol levels as well as...
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7538186 |
Exendins and exendin agonists modified with polyamino acids
Modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more molecular weight increasing compounds, for example, polyamino acids, polyethylene glycol polymers,...
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7534767 |
C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase
The present invention provides C-purine nucleoside analogs and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors RNA-dependent...
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7534766 |
Glucuronide metabolites and epimers thereof of tigecycline
A glucuronide metabolite of tigecycline, and its corresponding epimer, have been identified in humans treated with tigecycline. Mass spectral data have been used to identify these structures.
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7531503 |
Cell scaffold matrices with incorporated therapeutic agents
The invention is directed to methods and compositions for preparing matrices for controlled delivery of at least one therapeutic or biological agent to a target site in a subject. This is...
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7528114 |
C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth
Compounds of the formula:
are described, along with pharmaceutical compositions containing these compounds, and methods of using the compounds to prevent and to treat cancer in mammals,...
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7528113 |
Method and composition for the treatment of adenoviral ocular infections
Adenoviral infections and in particular ocular adenoviral infections, e.g. keratoconjunctivitis, can be treated or alleviated by the administration of a substance, interfering with the interaction...
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7524821 |
Scaffolded maleimide clusters for multivalent peptide assembly
Disclosed are scaffolded maleimide clusters, methods of making said clusters and use of said clusters as templates for multivalent peptide assembly. Multiple maleimide functionalities were...
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7524513 |
Biofunctional fibers
The present invention is directed to surface functionalization of polymeric fibers. Surface biofunctionalization is achieved by covalent conjugation of biofunctional igands and/or cell growth...
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7521434 |
Cross-linked gels of hyaluronic acid with hydrophobic polymers and processes for making them
The present invention provides for compositions of hyaluronic acid cross-linked with at least one other hydrophobic polymer to form a copolymer gel. The preferred composition is a formulation...
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7521068 |
Dry powder aerosols of nanoparticulate drugs
There invention discloses aqueous dispersions of nanoparticulate aerosol formulations, dry powder nanoparticulate aerosol formulation, propellant-based aerosol formulations, methods of using the...
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7517981 |
Efficient production method of ascopyrone P
A method for producing ascopyrone P from 1,5-D-anhydrofructose efficiently is provided. The method produces ascopyrone P by heating a solution of 1,5-D-anhydrofructose at a pH of 10 or less and a...
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7517858 |
Prodrugs of pharmaceuticals with improved bioavailability
Lipid prodrugs of pharmaceutical agents and their analogs that have increased anticancer, anti-viral, anti-inflammatory, anti-proliferative activity over the parent drug, and methods for making...
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7514410 |
Hepatitis C therapies
The invention provides methods for treating hepatitis C viral infections and related viral infections, as well as compounds and compositions that are useful for treating such infections.
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7511095 |
Thioester-terminated water soluble polymers and method of modifying the N-terminus of a polypeptide therewith
The invention provides reagents and methods for conjugating a polymer specifically to the α-amine of a polypeptide. The invention provides monofunctional, bifunctional, and multifunctional PEGs...
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7511026 |
Therapeutic agent for nerve damage
The present invention provides a therapeutic agent for nerve damages such as those caused by spinal cord injury or nerve trauma, which includes, as an active ingredient, a low-molecular-weight...
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7511022 |
Substituted indole-O-glucosides
Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
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7511020 |
Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides
This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for...
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7501399 |
Immunoeffector compounds
This invention provides compounds containing a 2-deoxy-2-amino-β-D-glucopyranose (glucosamine) glycosidically linked to an cyclic aminoalkyl (aglycon) group. The invention further provides methods...
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7498311 |
Treatment of migraine
A method for treating migraine in non-epileptic subjects which involves administering to subjects an effective amount of a pharmaceutical composition comprising a sulfamate of the following formula:
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7491709 |
Treatment with hyaluronic acid
The present invention relates, generally, to methods of providing long-term minimization of wrinkles or folds in the skin by injecting a bolus of hyaluronic acid deep into the skin. The methods of...
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7482330 |
Substituted fused heterocyclic C-glycosides
This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and...
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