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7109189 |
Mitochondrially targeted antioxidants
The invention provides mitochondrially targeted antioxidant compounds comprising a lipophilic cation moiety covalently coupled to a glutathione peroxidase mimetic. These compounds can be used to...
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7101562 |
Conjugate vaccines for the prevention of dental caries
The present invention provides glucan-based compositions and methods for stimulating an immune response against mutans streptococci components and vaccines and methods for the treatment and...
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7098188 |
Anticonvulsant derivative salts
The invention relates to novel pharmaceutically acceptable salts of anticonvulsant derivatives, processes for preparation of and pharmaceutical compositions containing said salts, useful in the...
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7094764 |
Substituted benzimidazole-, Benztriazole-, and benzimidazolone-O-glucosides
This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for...
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7094763 |
Substituted fused heterocyclic C-glycosides
This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and...
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RE39245 |
Galactopyranosides and their use
The present invention relates to simplified synthesis, new carbohydrate-based products and practical use of different carbohydrate-based products. Examples of these are (Galα1-3Gal),...
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7094762 |
Use of ribose to treat fibromyalgia
The present invention relates to methods and compositions comprising ribose and maleate for the treatment of fibromyalgia syndrome. The methods and compositions of the invention are especially...
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7084131 |
Method for preparing a polydispersed saccharide composition and resulting polydispersed saccharide composition
A method for preparing a polydispersed saccharide composition in which a fructan-containing material is dissolved in water prior to partial enzymatic treatment of the fructans.
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7084129 |
Antimicrobial quaternary surfactants based upon alkyl polyglycoside
The invention relates to a series of polyglycoside derivatives that contain water-soluble cationic groups introduced into the molecule by reaction with the hydroxyl groups present in the starting...
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7084132 |
Artemisinins with improved stability and bioavailability for therapeutic drug development and application
A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation...
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7084124 |
Substituted indazole-O-glucosides
Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
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7081448 |
Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure
wherein
R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are each, independently,...
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7078057 |
Process for producing nanometer particles by fluid bed spray-drying
Nanometer particles of poorly water-soluble or substantially water-insoluble compound are produced by finely-spraying a non-aqueous solution of said compound into a heated and fluidized bed of...
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7074775 |
Aminobutyramide conjugate and a pharmaceutical composition for treatment of neuronal disorders
A compound is provided that has the formula
NH 2 CH 2 CH 2 CH 2 C(O)N—R (I)
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7071181 |
Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
The present invention provides methods of treating diabetes and associated conditions by administering a composition including at least one sterol or 5α-stanol absorption inhibitor or compositions...
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7067498 |
Polymer controlled induced viscosity fiber system and uses thereof
The present invention relates generally to a method of blunting the postprandial glycemic response in a human by feeding an induced viscosity fiber system. The invention also relates to an induced...
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7064104 |
Methods of managing the symptoms of premenstrual syndrome
Methods of increasing the tryptophan:LNAA ratio in blood of an individual are taught. Such methods are useful in managing conditions such as premenstrual syndrome, perimenopause, menopause,...
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7064114 |
Gel-microemulsion formulations
A pharmaceutical composition adapted for use as a spermicide, the composition comprising a gel-microemulsion comprising an oil-in-water microemulsion and a polymeric hydrogel. The gel-microemulsion...
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7056890 |
Combination therapy for effecting weight loss and treating obesity
The present invention features a novel therapy for effecting weight loss which involves treating a subject with a sympathomimetic agent (e.g., phentermine or a phentermine-like drug) in combination...
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7056889 |
Compounds that bind P2Y2 or P2Y1 receptors
The invention provides peptides and compounds that can bind to P2Y 2 receptors that are useful for modulating the secretion of mucus within mucosal surfaces.
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7056702 |
Detecting lipocalin
The invention provides antibodies reactive with distinct lipocalin epitopes that are useful for detecting inflammation and bacterial infections in mammals.
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7053150 |
Segmented polymers and their conjugates
Segmented water soluble polymers, containing a higher molecular weight segment linked to a lower molecular weight segment, are described. In one embodiment, the polymer segments are poly(ethylene...
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7053059 |
Dialysis solutions with reduced levels of glucose degradation products
Dialysis solutions with enhanced biocompatibility are provided. The dialysis solutions include a first acidic solution and a second acidic solution that are admixed to form a ready-to-use dialysis...
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7053080 |
Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
The present invention provides methods for the treatment of obesity using sterol or 5α-stanol absorption inhibitors and compositions and therapeutic combinations including sterol or 5α-stanol...
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7049300 |
C-glycoside compounds for stimulating the synthesis of glycosaminoglycans
C-glycoside compounds are suited for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue, advantageously hyaluronic acid, and/or...
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7049339 |
Composition for the treatment of diseases which affect animals' hooves
A composition for treating a disease affecting the hoof of an animal comprising an active ingredient and a colloid former is described. The active ingredient may comprise zinc sulphate, copper...
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7049299 |
Method for preparing toothpaste using a specific sorbitol syrup, and sorbitol syrup
The invention concerns a method for preparing toothpaste comprising a sorbitol syrup as main humectant, at least an abrasive and at least a gelling agent. The invention is characterized in that it...
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7048918 |
Insect bait
Disclosed are insect baits for attracting insects such as ants, flies and cockroaches. The baits include amino acids and a sugar. The baits can be combined with an insect toxicant to effectively...
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7045494 |
Alkyl and/or alkenyloligoglycoside preparations having reduced magnesium salt concentrations
A process for making an alkyl and/or alkenyl oligoglycoside preparation having a magnesium salt concentration of less than about 10 ppm involving the steps of: (a) providing an alkyl and/or alkenyl...
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7041650 |
Anticonvulsant derivative salts
The invention relates to novel pharmaceutically acceptable salts of anticonvulsant derivatives, processes for preparation of and pharmaceutical compositions containing said salts, useful in the...
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7041651 |
Cellular uptake of bioactive agents
Provided is a composition and a method for increasing cellular uptake of bioactive agents, particularly those compounds termed “small molecules” into the cells of mammalian tissue, such as the...
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7041656 |
Sulfated fucoglucuronomannan
An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds...
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7037904 |
Use of N-acetyl-D-glucosamine in the manufacture of pharmaceutical useful for suppressing side-effect of radiotherapy and chemotherapy
The present invention has disclosed a use of N-acetyl-D-glucosamine in the manufacture of a medicament for inhibiting the side effect of radio-chemical therapy, the medicament with...
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7034011 |
Method of stabilizing reduced nicotinamide adenine dinucleotide or reduced nicotinamide adenine dinucleotide phosphate
It is an object of the present invention to provide a method of stabilizing reduced nicotinamide adenine dinucleotide or reduced nicotinamide adenine dinucleotide phosphate [hereinafter abbreviated...
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7030092 |
Ultra-high fiber supplement and method of reducing weight cardiovascular risks and ingested toxins.
An improved ultra-high fiber supplement that promotes satiety, caloric reduction, and weight loss. The supplement comprises guar, oat, psyllium, locust bean gum, pectin, green tea,...
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7026298 |
Oral rehydration compositions
The present invention is directed to a zinc supplemented ORS and its use in the treatment of diarrhea.
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7022678 |
Pregabalin lactose conjugates
In accordance with the present invention, there is provided pregabalin lactose conjugate compounds. Also provided as part of the present invention is a novel method of central nervous system...
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7018983 |
Treatment of migraine
A method for treating migraine in non-epileptic subjects which involves administering to subjects an effective amount of a pharmaceutical composition comprising a sulfamate of the following formula:
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7014856 |
Ganglioside-KLH conjugate vaccines plus OS-21
This invention provides a vaccine for stimulating or enhancing in a subject to which the vaccine is administered, production of an antibody which recognizes a ganglioside, comprising an amount of...
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7015207 |
Use of N-acetyl-D-glucosamine in the manufacture of pharmaceutical useful for preventing and treating sexual disorder
The present invention has disclosed a use of N-acetyl-D-glucosamine in the preparation of a medicine for preventing and treating the sexual disfunction. The preparation taken N-acetyl-D-glucosamine...
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7015200 |
Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers
The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the...
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7011845 |
β-glucans encapsulated in liposomes
Liposomes encapsulating a β-glucan have an improved activity of enhancing a cellular immunity, especially when they are transmucosally administered. Thus, the liposomes are useful for the...
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7012068 |
Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
Methods and compositions for treating cancer with a formulation are provided in which a polysaccharide, galactomannan, is co-administered with a therapeutic agent to a subject to reduce toxicity...
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7008627 |
Use of complexes for the preparation of compositions for the treatment of sensitive skin, preparation process and hypoallergenic compositions
This invention relates to new dermocosmetic and pharmaceutical compositions which are useful for improving and treating hyperreactive skin conditions and more generally allergic-type reactions...
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7005422 |
Derivatives of monosaccharides as cell adhesion inhibitors
This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-α-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful,...
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7001601 |
Ganglioside-KLH conjugate vaccine plus QS-21
This invention provides a vaccine for stimulating or enhancing in a subject to which the vaccine is administered, production of an antibody which recognizes a ganglioside, comprising an amount of...
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7001888 |
Compositions and methods for treating cancer
Methods and compositions are provided for the treatment of cancer that take advantage of the increased uptake of glucose-anti-neoplastic agent conjugates in cancer cells relative to normal cells.
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7001618 |
Nutritional composition for weight management
A composition and method is provided for promoting weight loss in a mammal by feeding effective amounts of at least three nutrients selected from L-carnitine, chromium, Vitamin A, and a source of...
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7001604 |
Cosmetic composition
A cosmetic composition, especially for use on aged and/or stressed skin is described, whereby apart from water at least one substance forming lamellar structures with water is present in the...
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6998392 |
Formulation to treat or prevent parasitic infection
The invention provides a formulation for treatment or prevention of a parasitic infection such as a protozoan or helminths infection, for example: Giardia . The formulation comprises at least one...
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