Patents in Class 514/226.800

Matches 51 - 100 out of 136

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Match	Document	Document Title
51	5719145	Amidine derivatives and platelet aggregation inhibitor containing the same The invention relates to a substituted amidine derivative which has an excellent platelet aggregation inhibiting action on the basis of fibrinogen antagonism and is particularly excellent in...
52	5712295	Agonists and antagonists of the nicotinic acetylcholine receptors of insects to control endoparasites Use of agonists and antagonists of the nicotinergic acetylcholine receptors of insects for combating endoparasites is disclosed.
53	5693661	Anti-viral compounds Certain vinyl acetylene benzimidazole compounds which inhibit the growth of picornaviruses, such as rhinoviruses, enteroviruses, cardioviruses, polioviruses, coxsackieviruses of the A and B groups,...
54	5686454	Camphorcarbonyl The invention is directed to a series of novel compounds of the formula ##STR1## where Y is carbonyl or sulfonyl; R 7 and R 8 are alkyl, or R 7 and R 8 , together with the carbon to which they...
55	5654294	Spiro lactam dual action inhibitors Compounds of the formula ##STR1## are disclosed as possessing inhibotory activity against angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) and thus being useful as cardiovascular...
56	5616579	Anti-ulcer pyridyloxy derivatives, their preparation and uses Compounds of formula (I): ##STR1## [wherein: R 1 is a cyclic amino group, or a dialkylamino group; R 2 a group of formula --NHCHR 3 R 4 wherein R 3 and R 4 are each alkyl aryl or aralkyl, or...
57	5604224	Substituted heterocyclylisoquinolinium salts and compositions and methods of use thereof Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries...
58	5599809	Method for improving reproductive efficiency in farm animals Oxytocin receptor antagonists of the formula ##STR1## wherein R 12 is hydrogen, alkoxycarbonyl or unsubstituted of substituted alkyl; R 13 is hydrogen, alkoxyl, aralkoxyl, alkoxycarbonyl,...
59	5569655	Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries...
60	5567700	Therapeutic heterocycles which antagonize neurokinin receptors Compounds of formula I ##STR1## wherein G, J, L, M, m and D have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide...
61	5543433	Azine-substituted phenylacetic acid derivatives and fungicides containing these Compounds of the formula I ##STR1## where X is hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, cyano or nitro, Y is an amino, methylamino or dimethylamino group, Z is a group CHCH 3 ,...
62	5538967	Arthropodicidal oxazines and thiazines Substituted oxazines and thiazines, arthropodicidal compositions containing them and methods of controlling arthropods are provided. The oxazines and thiazines having the formula ##STR1## wherein Z...
63	5536715	Combinations of anthelmintically active agents Pharmaceutical compositions comprising a compound of formula (I) and at least one other anthelmintically active compound, being an avermectin or a milbemycin, are useful in the treatment of...
64	5532259	Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides, pharmaceuticals containing these compounds and their use Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides, pharmaceuticals containing these compounds and their use Isoxazole-4-carboxamide derivatives and hydroxyalkylidene-cyanoacetamide...
65	5521176	Agrochemical compositions containing certain N-heterocycligs, compounds and stabilizer Compositions which contain, as the active ingredients, a combination of heterocyclic compounds of the general formula (I) and organophosphorous compounds, in addition to one or more compounds...
66	5510353	Certain aminoguanidine compounds, pharmaceutical compositions containing them and their use in treating gastrointestinal motility disorders and disorders associated with cephalic pain Compounds of formula A--X--Y--NH--B wherein A is derived from optionally substituted benzothiophene, indole, 4-aza-and 7-aza-benzothiophene or-indole, A bearing in position 5 hydrogen, halogen,...
67	5496830	Inhibition of hemoflagellates by camptothecin compounds Camptothecin compounds are effective inhibitors of hemoflagellate growth and are useful in treating leishmaniasis and trypanosomiasis in livestock, other domestic animals and humans.
68	5466687	Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula ##STR1## (wherein n, m, p, A, W 1 , W 2 , X, Y, and R 1 to R 11 are as defined in claim...
69	5434163	Treatment of Cryptococcus neoformans infection A method of treatment of Cryptococcus neoformans infection by administering to a patient in need thereof an effective amount of a benzimidazile compound.
70	5424307	1,3-/1,4-thiomorpholino-terminated non-peptidyl α-succinamidoacyl aminodiols as anti-hypertensive agents Non-peptidyl compounds characterized generally as α-succinamidoacyl aminodiols having a 1,3-thiomorpholino-type group or a 1,4-thiomorpholino-type group at the N-terminus are useful as renin...
71	5420125	Nitromethylene compounds Nitromethylene compounds of general formula ##STR1## wherein R represents a hydrogen atom or an alkyl group, R 1 represents a hydrogen atom or an alkyl group, n is 0 or 1, and Het represents an...
72	5403841	Use of carrageenans in topical ophthalmic compositions Topical ophthalmic compositions of carrageenans which are administrable as a drop but which become more viscous or gel upon instillation in the eye are disclosed. Methods for use of the...
73	5382576	1-aza-1-arylcycloalkanes as topical glaucoma treatment agents Topical treatments for glaucoma using 1-Aza-1-arylcyloalkanes as the treatment agents.
74	5364868	Amino-substituted benzoylguanidines, process for their preparation, their use as a medicament and medicament containing them Amino-substituted benzoylguanidines, process for their preparation, their use as a medicament and medicament containing them Benzoylguanidines of the formula I ##STR1## are described in which R(1)...
75	5338743	New use of the adenosine antagonist The present method for the treatment of pancreatitis, which comprises administering an effective amount of a pyrazolopyridine compound of the following formula: ##STR1## wherein R 1 is lower...
76	5284647	Mesotetraphenylporphyrin complex compounds, process for their production and pharmaceutical agents containing them Porphyrin complex compounds, consisting of a mesotetraphenylporphyrin ligand, optionally at least one ion of an element with atomic numbers 13, 21, 32, 37-39, 42-44, 49, 50 or 57-83 as well as...
77	5260310	Oxetanone compounds and pharmaceutical compositions containing them Novel compounds of the formula ##STR1## wherein Q, R 1 and R 2 are described herein, are disclosed along with pharmaceutical compositions, methods of use, and process for producing compounds of...
78	5250521	Substituted pyrazolopyrimidines as angiotensin II antagonists Novel substituted pyrazolopyrimidines of formula (I) which are useful as angiotensin II antagonists, are disclosed. ##STR1##
79	RE34299	1-(4'-fluorophenyl)-3,5-substituted indoles useful in the treatment of psychic disorders and pharmaceutical compositions thereof The present invention relates to novel indole derivatives which have interesting pharmacodynamic effects indicating pronounced activity in the treatment of psychic disorders, especially psychoses...
80	5202324	Imidazopyridazines The imidazo[1,2-b]pyridazine compounds of the formula: ##STR1## wherein R 1 is a hydrogen or halogen atom, or a lower alkyl group optionally having substituent(s), R 2 and R 3 are,...
81	5177072	Treatment of autoimmune inflammatory, and psoriatic diseases with heterocyclic aminoalkyl esters of mycophenolic acid and derivatives Heterocyclic aminoalkyl esters of mycophenolic acid, and the derivatives and pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, anti-inflammatory agents, anti-tumor...
82	5162325	Angiotensin II antagonists incorporating a substituted benzyl element Substituted heterocycles attached through a methylene bridge to novel substituted phenyl derivatives of the Formula I are useful as angiotensin II antagonists. ##STR1##
83	5137886	Insecticidal compounds The invention provides insecticidally active compounds of formula (I): ##STR1## wherein X is nitrogen or carbon bearing a hydrogen atom; R 1 is a group of formula --S(O) n --Y, wherein Y is an...
84	5124322	Dipeptide collagenase inhibitors Novel compounds of formula (I), salts, solvates and hydrates thereof: ##STR1## in which: R 1 and R 2 are independently hydrogen; alkyl; alkoxy; halogen; or CF 3 ; R 3 is hydrogen; acyl, such...
85	5096902	Heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same The invention relates to novel nitrogen- and sulfur-containing heterocyclic compounds of the formula (I), acid addition salts thereof, pharmaceutical compositions containing them and a process for...
86	5096914	Novel benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds Benzopyran derivatives of the general formula I ##STR1## wherein the substituents are as defined herein are provided. The compounds show vasodilating and vascular spasmolytic activity and are...
87	5084459	Tetrahydropyrimidines, their production and use There is provided a pest control composition containing a compound represented by the formula, ##STR1## wherein R 1 , R 2 , R 3 and R 4 are the same or different and independently mean a hydrogen...
88	5075316	Pest control compositions Novel compounds of the formula ##STR1## in which: R 1 and R 2 independently of one another are hydrogen, halogen, C 1 -C 3 alkyl, C 1 -C 2 halogenoalkyl, C 1 -C 3 alkoxy or C 1 -C 3 ...
89	4994493	N-substituted 5-nitroanthranilic acids, a process for their preparation, their use, and pharmaceutical products based on these compounds Compounds I ##STR1## with R equal to hydrogen or (C 1 -C 4 )-alkyl, X equal to (CH 2 ) n with n=1-4, unsubstituted or substituted, and Ar is equal to an aromatic or heteroaromatic system,...
90	4987132	Saturated heterocyclic carboxamide derivatives A saturated heterocyclic carboxamide derivative of the following general formula (I) and salts thereof which have platelet activating factor (PAF) antagonizing activity. ##STR1##
91	4981864	Method for inhibition of erythrocyte aggregation using anellated tricyclic compounds The present invention is concerned with the use of compounds of the general formula: ##STR1## wherein R 1 is a phenyl radical of the general formula: ##STR2## or R 1 is a 5 or 6 membered...
92	4973593	Novel compounds for the treatment of hypertension Compounds of the formulae: ##STR1## are useful as anti-hypertensives.
93	4957941	Anti-spasmdoic agents having an acetylenic bond A new class of anti-spasmodic compounds having two branch chains is provided. The compounds have the general formula: ##STR1## where Y is H or OH; j is an integer from 0 to 4; k is an integer...
94	4954509	Isoquinoline derivatives and their use as analgesics A compound, or a solvate or salt thereof, of formula (I): ##STR1## in which: RCO is an acyl group in which the group R contains a substituted or unsubstituted carbocyclic aromatic or heterocyclic...
95	4925845	2 heteroaryl 3,3 dialkyl-5-(3 oxo-2,3,4,5 tetrahydro-6 pyridazinyl)-3H-indoles Gem 3 dialkyl or spiro 4 aryl or heteroaryl 5 heterocyclic 3 H indoles and their pharmaceutically acceptable salts are prepared. They are useful for reducing blood pressure producing a positive...
96	4916124	Indoloquinoxalines with substituents in 6-position containing cyclic groups as antiviral agents Novel indoloquinoxalines having substituents in 6-position containing cyclic groups, of the general formula I ##STR1## wherein R 1 represents hydrogen or one or several preferably 1 to 4, similar...
97	4904660	Histidine derivatives as superior renin inhibitors Novel compounds of the following formula (I) and their salts: A compound of the formula (I) ##STR1## These compounds are expected to be useful for renin inhibitors. Thus, the compounds are useful...
98	4877785	Non-peptidyl beta-succinamidoacyl aminodiols as anti-hypertensive agents Non-peptidyl compounds characterized generally as β-succinamidoacyl aminodios are useful as renin inhibitors for the treatment of hypertension.
99	4863945	Pyrrolobenzimidazoles and pharmaceutical compositions containing them Pyrrolobenzimidazoles of the formula: ##STR1## are useful for treatment of heart and circulatory diseases. R 1 is substituted phenyl; or optionally substituted naphthyl or a five- or six-membered...
100	4831032	Cardiotonic benzimidazoles The present invention provides benzimidazoles of the general formula: ##STR1## wherein R 1 , X, A, and R 2 are as defined in the specification. The present invention also provides processes for...

Matches 51 - 100 out of 136

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