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7253164 Bicyclic compounds and compositions as PDF inhibitors  
This invention is directed to novel bicyclic compounds, to the uses of these compounds in various medicinal applications, including treating disorders amenable to treatment by peptidyl deformylase...
7253160 Depeptidized inhibitors of hepatitis C virus NS3 protease  
The present invention discloses novel depeptidized compounds which have HCV protease inhibitory activity as well as pharmaceutical compositions comprising such compounds and methods of using them...
7199118 Benzothiazine derivatives, their preparation and use  
This invention relates to novel benzothiazine derivatives of Formula I useful as modulators of the AMPA sensitive glutamate receptors, pharmaceutical compositions comprising such compounds and...
7141566 Benzoxazine and benzothiazine derivatives and the use thereof in medicaments  
The invention relates to compounds of formula (I), the tautomeric and isomeric forms and salts thereof, in addition to a method for production and use thereof in medicaments.
7138394 Vehicle for topical delivery of anti-inflammatory compounds  
A vehicle for topical delivery which contains a liquid eutectic mixture of hydrophobic compounds.
7125868 Thienothiazine compound having anti-inflammatory and analgesic properties and method of making and using the same  
The present invention is related to a type of thienothiazine compounds having molecular structure of formula (1) and their pharmaceutically acceptable salts or solvates. The present invention is...
7105512 Ophthalmic aqueous pharmaceutical preparation  
The present invention provides an ophthalmic aqueous pharmaceutical preparation, which is excellent in anti-inflammatory effect, which is less stimulative and which has high safety and excellent...
7030162 Treatment of migraine headache  
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs...
7026313 2-thia-1,6,8-triaza-naphthalene-2,2-dioxides are kinase inhibitors  
The present invention provides 2-thia-1,6,8-triaza-naphthalene-2,2-dioxide inhibitors of cyclin-dependent kinases, uses thereof and pharmaceutical compositions thereof. These compounds are useful...
6894041 Oxazolyl-acid amide derivatives useful as inhibitors of PDE4 isozymes  
This application is directed to compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic...
6869948 Meloxicam for oral administration  
The invention relates in its first aspect to a rapidly decomposing tablet for pain therapy containing meloxicam...
6869945 Pyrrolyl-and imidazolyl-acid amide derivatives useful as inhibitors of PDE4 isozymes  
This application is directed to compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic...
6867236 Method of preventing of delaying the onset and progression of Alzheimer's disease and related disorders  
The present invention relates, in general, to a method of preventing or delaying the onset of Alzheimer's disease and related neurodegenerative disorders. The invention also relates to a method of...
6844338 Piperidyindoles as serotonin receptor ligands  
A pharmaceutical compound of the formula (I) in which R 1 and R 2 are each hydrogen or C 1-6 alkyl, R 3 is —SR 10 , —SOR 10 , —SO 2 R 10 , —COR 10 , —CH 2 OH or —CONHR 11 , where R...
6811768 Use of inhaled NO as anti-inflammatory agent  
A method for lessening or preventing non-pulmonary ischemia-reperfusion injury or inflammation in a mammal by identifying a mammal which has ischemia-reperfusion or is at risk for developing...
6756370 Piperidine alcohols  
The invention relates to compounds of formula (I), wherein R 1 , R 2 and A have the meanings given in claim 1, are potent 5-HT 2A antagonists and are suitable for treating psychoses,...
6713463 Methods and compositions for treating and preventing mucositis  
A method of reducing or inhibiting mucositis in a patient, which includes administering an inflammatory cytokine inhibitor or a mast cell inhibitor, or a combination thereof, is disclosed.
6682747 Process for preparing an oral suspension of a pharmaceutical substance  
The present invention relates to orally administered suspensions of pharmaceutical active substances of the NSAID type, particularly the antirheumatic agent Meloxicam, which are stabilized by the...
6667056 Pharmaceutical compositions containing an effervescent acid-base couple  
A pharmaceutical formulation in the form of a fast dissolving tablet comprising an active ingredient, sodium glycine carbonate and an acid capable of reacting rapidly with sodium glycine carbonate...
6664251 Benzothiazine derivative  
Disclosed are benzothiazine derivatives represented by the following formula (I): wherein the dashed line indicates the presence or absence of a bond; Z represents one of the following groups: ...
6620853 Methods and compositions for prevention and treatment of restenosis with non-steroidal anti-inflammatory drugs  
Methods and compositions for the prevention and/or treatment of vascular restenosis, the methods comprising administering to individuals in need thereof, an effective amount of a non-steroidal...
6605627 Modulators of peroxisome proliferator activated receptor-gamma, and methods for the use thereof  
In accordance with the present invention, there is provided a class of compounds which are capable of modulating processes mediated by peroxisome proliferator activated receptor-gamma (PPAR-γ)....
6482814 Biocidal composition and its use  
A composition comprising a C 3-5 -alkyl-1,2-benzisothiazolin-3-one and the metal complex of a cyclic thiohydroxamic acid such as the 2:1 zinc salt of either 3-hydroxy-4-methylthiazol-2(3H)-thione...
6440963 Use of selective COX-2 inhibitors for the treatment of urinary incontinence  
The treatment of neuromuscular dysfunction of the lower urinary tract by compounds which selectively inhibit the COX-2 isozyme is described. The compounds concerned inhibit the COX-2 isozyme with a...
6440962 Certain benzothiazine dioxide endothelin antagonists and processes for their preparation  
The instant invention is a series of benzothiazine dioxides, or a pharmaceutically acceptable salt thereof, which are potent endothelin A antagonists with profound in vitro activity, and improved...
6436927 IL-8 receptor antagonists  
The present invention involves certain 8-ureido and 8-thioureido, 1,2-benzothiazines, 1,2,4-benzothioxazines and 1,2,4-benzothiodiazines useful in the treatment of disease states mediated by the...
6337327 Pharmaceutical compositions comprising an aldose reductase inhibitor and an ace inhibitor  
The invention relates to pharmaceutical compositions comprising an aldose reductase inhibitor and an ACE inhibitor, and their use in the treatment of diabetic complications such as diabetic...
6329366 Pharmaceutical compounds  
A pharmaceutical compound of the formula ##STR1## in which R 1 and R 2 are each hydrogen, halo, cyano or methyl, the dotted line represents an optional double bond, ##STR2## where R 4 and R 5...
6316443 Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a β-adrenergic antagonist  
Combinations of a β-adrenergic antagonist and a topical carbonic anhydrase inhibitor are particularly useful in the treatment of ocular hypertension, especially in patients insufficiently...
6242442 Brinzolamide and brimonidine for treating ocular conditions  
Methods and compositions for treating ocular conditions which find their etiology in compromised ocular blood flow with brinzolamide and brimonidine are disclosed.
6242441 Use of brinzolamide to prevent visual field loss  
Methods for preventing or slowing visual field loss are disclosed.
6218373 Formulations containing hyaluronic acid  
A method of treating a disease of condition administering topically to the skin or exposed tissue of a human, a dosage amount of a pharmaceutical composition, said dosage comprising a...
6184220 Oral suspension of pharmaceutical substance  
The present invention relates to orally administered suspensions of pharmaceutical active substances of the NSAID type, particularly the antirheumatic agent Meloxicam, which are stabilized by the...
6166004 Combinations of HIV protease inhibitors with reverse transcriptase inhibitors  
There are described compounds of formula I*, ##STR1## wherein R 1 is lower alkoxycarbonyl, R 2 is secondary or tertiary lower alkyl or lower alkylthio-lower alkyl, R 3 is phenyl that is...
6160018 Prophylactic composition and method for alzheimer's Disease  
A method of preventing or delaying the onset of symptoms of Alzheimer's Disease includes the step of administering to a patient in need of such treatment a composition having an effective...
6096771 Isoxazole derivatives  
An isoxazole compound having the following formula: ##STR1## wherein R 1 represents hydrogen, halogen, alkyl, alkoxy, hydroxyl, alkylthio, amino, alkanoyl, alkanoylamino, alkanoyloxy,...
6063783 Analgesic use of triazolo-pyridazine derivatives  
A class of substituted 7,8-ring fused 1,2,4-triazolo[4,3-b]pyridazine derivatives as shown in Formula I, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the...
6051566 Anti-reactive anti-asthmatic activity of non-steroidal anti-inflammatory drugs by inhalation  
Non-steroidal anti-inflammatory drugs proved to be effective drugs for combating and preventing asthma if administered by inhalation. Useful are for instance acetylsalicylic acid, and indomethacin,...
6017900 Topical composition containing hyaluronic acid and nsaids  
A pharmaceutical composition comprising a plurality of effective non-toxic dosage amounts of a composition for topical administration to the site of pathology or trauma of skin or exposed tissue of...
6013652 Spiro-substituted azacycles as neurokinin antagonists  
Disclosed are spiro-substituted azacycles of formula I are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of...
RE36419 Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx  
The present invention provides novel methods for prevention or treatment of primary and recurring squamous cell carcinoma of the oral cavity or oropharynx comprising topical administration, to the...
5985860 System for transdermal delivery of pain relieving substances  
Compositions for pain relieving non-steroidal anti-inflammatory drugs and/or medicaments such as ibuprofen, methotrexate, capsaicin, diphenhydramine, aspirin, methyl-nicotinate and other...
5972975 Substituted 2-aminopyridines as inhibitors of nitric oxide synthase  
Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders....
5939442 Modulations of peroxisome proliferator activated receptor-γ, and methods for the use thereof  
In accordance with the present invention, there is provided a class of compounds which are capable of modulating processes mediated by peroxisome proliferator activated receptor-gamma (PPAR-γ)....
5932572 Topical anti-glaucoma compositions  
Ophthalmic pharmaceutical compositions useful in controlling elevated intraocular pressure associated with glaucoma and ocular hypertension are described. The compositions comprise a combination of...
5773437 Alkylenediamine derivatives  
The present invention relates to alkylenediamine derivatives which relieve urinating contraction and therefore are of value as active ingredients of therapeutic agents for treating dysuria.
5736536 Method for treating vascular leak syndrome  
A novel method for preventing, stabilizing or causing regression of vascular leak syndrome is disclosed. The method comprises administering to a patient in need thereof a compound selected from the...
5719151 Substituted benzene compounds  
Phthalazinedione compounds and pharmaceutical compositions are described. The compositions are useful in treating human or animal patients to alleviate or cure disease or disease symptoms caused by...
5691333 Pesticidal 1-arylpyrazole-3-carboximidothoic acid esters  
1-(Substituted phenyl)-3-(thioimidate)pyrazoles having systemic activity, arthropodicidal (especially insecticidal) and nematocidal compositions comprising same and methods for controlling...
5679678 Thienithiazine derivatives  
Thienothiazine derivatives of the formula ##STR1## are provided. These derivatives are useful for the treatment of inflammation and pain.
Matches 1 - 50 out of 124 1 2 3 >