Patents in Class 514/217.1

Matches 1 - 50 out of 88

1 2 >

Match	Document	Document Title
1	7834003	5-aminopyrazole derivatives as pesticidal compounds The invention relates to 5-Aminopyrazole derivatives of formula (I) or salts thereof, a process for their preparation, to compositions thereof and to their use for the control of pests, including...
2	7781426	CETP inhibitors Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing...
3	7414048	4,5-dihydro-isoxazole derivatives and their pharmaceutical use The present invention is concerned with the compounds of formula wherein m, n and p are each independently 0 or 1 and q is 0, 1, 2, 3, 4 or 5; -A1=A2-A3=A4- is a pyridinylidene, pyridazinylidene,...
4	7405209	Protease inhibitors The present invention provides 4-amino-azepan-3-one protease inhibitors and pharmaceutically acceptable salts, hydrates and solvates thereof which inhibit proteases, including cathepsin K,...
5	7319097	Compounds The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the...
6	7304052	Substituted homopiperidinyl benzimidazole analogues as fundic relaxants The present invention relates to compounds of formula (I) their prodrugs, N-oxides, addition salts, quaternary amines and stereochemically isomeric forms, wherein the bivalent radical -{circle...
7	7300928	Benzimidazolidinone derivatives as muscarinic agents Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor...
8	7265103	Substituted amino isoxazoline derivatives and their use as anti-depressants The invention concerns substituted amino isoxazoline derivatives, more in particular tricyclic dihydrobenzopyranoisoxazoline, dihydroquinolinoisozazoline, dihydronaphthalenoisoxazoline and...
9	7229987	Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes The present invention relates to a melanin concentrating hormone antagonist compound of formula I: (I); or a pharmaceutically acceptable salt, solvate, enantiomer or prodrug thereof useful in the...
10	7091199	Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists The compounds are of the class of thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives, useful as D4 antagonists. Said compounds are useful for the treatment of medical conditions...
11	7071184	Protease inhibitors The present invention provides C1-6alkyl-4-amino-azepan-3-one protease inhibitors and pharmaceutically acceptable salts, hydrates and solvates thereof which inhibit proteases, including cathepsin...
12	7008957	Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments The invention relates to compounds of the formula I in which the radicals have the stated meanings, their stereoisomeric forms and their physiologically tolerated salts and process for their...
13	6887864	Azepane derivatives This invention provides novel azepane derivatives or pharmaceutically acceptable salts thereof, according to the general formula (I) wherein the symbols are defined in the specification, as well as...
14	6667303	Aryl substituted 1,4-diazepanes and method of use thereof Aryl substituted 1,4-diazepanes are provided such as derivatives of 6-(1,4-diazepan-1-yl)benzo[cd]indol-2(1H)-one, 6-(1,4-diazepan-1-yl)acenaphthylen-1(2H)-one and...
15	6544982	Thrombin receptor antagonists A thrombin receptor antagonist having the formula useful for inhibiting the aggregation of blood platelets. The compounds can be used in a method of acting upon a thrombin receptor which comprises...
16	6521659	Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in...
17	6500817	Thiazolyl urea derivatives and their utilization as antiviral agents The present invention relates to thiazolylurea derivatives, a process for their preparation, and their use as pharmaceuticals, in particular as antiviral pharmaceuticals.
18	6436980	Peptidomimetic efflux pump inhibitors Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such...
19	6420395	Azacyclooctane and heptane derivatives, their preparation and use in therapy The present invention discloses compounds of formula (1) or (2), any of its enantiomers or any mixture thereof, or a pharmaceutically acceptable salt thereof; wherein n is 0, or 1; R is hydrogen,...
20	6335326	Benzisoxazole derivatives having d4-antagonistic activity The present invention relates to a group of novel benzisoxazole derivatives which are potent and selective antagonists of the dopamine D4-receptor. The compounds have general formula (I) wherein...
21	6251921	Antithrombotic diamines This application relates to the use as thrombin inhibitors, coagulation inhibitors and thromboembolic disorder agents of diamines of formula I as defined herein. It also provides novel compounds of...
22	6211214	Biphenyl ether oxazolines and their use as pest-control agents The present invention relates to novel biphenyl ether-oxazolines of the formula (I) ##STR1##in which X, Y, Z, R1, R2, A, m and n have the meaning given in the description, to processes for their...
23	6191152	2-(1,2,4-triazole-1-yl)-1,3,4-thiadiazole derivatives having an effect on the C.N.S. and the heart The invention refers to novel 2-(1,2,4-triazole-1-yl)-1,3,4-thiadiazole derivatives of formula (I) having an influence on the heart and the central nervous system, furthermore pharmaceutical...
24	6166041	2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma Novel compounds which are effective PDE IV inhibitors are disclosed. The present invention is directed to compounds having the general formula I ##STR1## wherein: X is a halogen; Q is --CH2 --CH2...
25	6022868	Substituted azacyclic or azabicyclic compounds
26	6022880	Substituted pyridylamino indoles There are disclosed various compounds of the formula below, ##STR1## where R, R1, W, X, Y and Z are as defined in the specification; which are useful for alleviating various memory dysfunctions...
27	5872134	5-HT4 receptor antagonists The use of a compound of formula (I) or a pharmaceutically acceptable salt thereof for the treatment of artrial arrhythmia, stroke or CNS disorders X--CO--CH2 --Z (I)wherein X is a monocyclic or...
28	5856360	Pharmaceutical method for the treatment of severe blood loss and for the inhibition or treatment of hemorrhagic shock This invention is directed to a pharmacologically acceptable composition for inhibiting or treating hemorrhagic shock in a mammal. The composition includes a KATP inhibitor and a pharmacologically...
29	5705509	Tricyclic heterocyclic compounds as 5-HT4 receptor antagonists Compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein X1 --(CH2)x --X2 and the aromatic carbon atoms to which they are attached form 5-7 membered ring wherein X1 is O or...
30	5703070	Indole, indazole and benzisoxazole compounds Compound of formula (I): ##STR1## in which: R1 represents hydrogen, halogen, alkyl, alkoxy, trihalomethyl or hydroxyl, R2 represents hydrogen, alkyl or phenyl which is optionally substituted,...
31	5703065	Heteroarylamino and heteroarylsulfonamido substituted 3-benyzlaminomethyl piperidines and related compounds The invention relates to compounds of the formula ##STR1## and to pharmaceutically acceptable salts thereof, wherein A, W, P, R3, Q and R1 are as defined herein. The compounds of formula I, and...
32	5698573	Imidazolone and oxazolone derivatives as dopamine antagonists A class of imidazolone and oxazolone derivatives of Structure I, ##STR1## wherein X represents oxygen or N--R1 ; Q represents a substituted five-, six- or seven-membered monocyclic heteroaliphatic...
33	5614535	Adhesion receptor antagonists Compounds of the formula I ##STR1## in which R1 and X have the meanings herein defined, their physiologically unobjectionable salts and/or solvates inhibit the binding of fibrinogen to the...
34	5512569	Aminoalkyl benzothiazolinones The invention relates to the compounds of formula (I): ##STR1## in which R1 and R2 are as defined in the description, the optical isomers thereof,and an addition salt thereof with a...
35	5502066	1,2,4-dithiazolium salts as chemotherapeutics The invention relates to the use of 1,2,4-dithiazolium salts, some of which are known, of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to a...
36	5500443	New benzodioxane compounds A compound of formula (I): ##STR1## in which: X represents oxygen or methylene, n represents 1, 2 or 3, R1 represents hydrogen, aminocarbonyl or hydroxymethyl, R2 represents: ##STR2## in which R3...
37	5491149	Dihydroxypropylamine containing retroviral protease inhibitors This invention relates to substituted dihydroxypropylamines, a process to prepare intermediates useful for the synthesis of these compounds, compositions comprising such compounds, and a method of...
38	5466687	Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula ##STR1## (wherein n, m, p, A, W1, W2, X, Y, and R1 to R11 are as defined in claim 1) and...
39	5447929	Method of treating joint disorders using hydroxamic derivatives Hydroxamic acid derivatives of the fdrrnula ##STR1## and pharmaceutically acceptable salts thereof, which are collagenase inhibitors useful for the control or prevention of degenerative joint...
40	5385916	4-(1,2-benzisoxazolyl)piperidine antipsychotic agents Certain 1-substituted 4-(1,2-benzisoxazolyl)-piperidine compounds exhibit neuroleptic activity and are useful in the treatment of psychosis and anxiety.
41	5340826	Pharmaceutical agents for treatment of urinary incontinence The present invention relates to a method of treating or preventing urinary incontinence in mammals, including humans, using certain quinuclidine derivatives, piperidine derivatives, azanorbornane...
42	5324723	Oxazoles and thiazoles for the treatment of senile dementia 1,3-Oxazole and 1,3-thiazole compounds of formula I, and their pharmaceutically acceptable salts and prodrugs: ##STR1## wherein X represents oxygen or sulphur; R1 represents a non-aromatic...
43	5312818	Method of protecting against and/or treating ulcerative gastrointestinal conditions using a thromboxane A2 receptor antagonist and combination useful in preventing and/or treating ulcers and/or inflammation A method is provided for protecting against and/or treating ulcerative gastrointestinal conditions, including anti-inflammatory drug-induced gastrointestinal ulcers, using a thromboxane A2 receptor...
44	5246927	Benzazole derivatives, processes for their preparation containing such compounds and the use thereof The invention relates to new benzazole derivatives of the formula I ##STR1## wherein X is oxygen or sulphur, R1 is lower alkyl, lower alkenyl or cycloalkyl, R2 and R3 independently of one another...
45	5223523	Fungicidal oxazolidinones Compounds for an methods of controlling plant diseases using thiooxazolidinones, oxazolidindiones and agriculturally suitable compositions containing them are disclosed.
46	5219852	Substituted thiazoles and oxazoles and pharmaceutical compositions and methods thereof Substituted thiazoles, oxazoles and 2-hydroxy morpholine compounds useful in the treatment of diabetes mellitus and obesity are described.
47	5135927	Microbicidal composition A microbicidal composition contains as active ingredient 2-chloro-4-trifluoromethylthiazol-5-carboxylic acid derivatives of the formula I ##STR1## R is an organic radical with up to 40 carbon...
48	5059620	Aryl substituted aminomethyl benzene derivatives The present invention relates to new compounds of the formula ##STR1## wherein X is ##STR2## wherein R1 is hydrogen, lower alkyl, phenyl, benzyl, cinnamoyl, thiophene, furan, pyrrole, imidazole,...
49	5055466	N-morpholino derivatives and their use as anti-hypertensive agents Compounds of the formula ##STR1## are disclosed. These compounds are inhibitors of renin and therefore useful as cardiovascular agents.
50	5051420	4-substituted-3-1H-imidazol-1-,2,5-thiadiazoles as antiarrhythmic agents Invention compounds of the formula: ##STR1## wherein Z is ##STR2## are novel. Compounds of the above formula have shown antiarrhythmic activity in an electrophysiological assay.

Matches 1 - 50 out of 88

1 2 >