Matches 151 - 200 out of 209 < 1 2 3 4 5 >


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4863949 Aminopropanol derivatives, processes for the preparation thereof, the use thereof and pharmaceutical compositions containing them  
The present invention provides compounds of the general formula: ##STR1## wherein Ar is a substituted or unsubstituted aromatic or heteroaromatic radical, A is a straight-chained or branched...
4863935 Mitomycin compounds having useful anti-tumor activity  
Mitomycin derivatives having potent anti-tumor activity against solid sarcoma 180 tumors and lymphocytic leukemia P-388 tumors.
4851406 Heterocyclic-substituted indoles and pharmaceutical compositions containing them  
The present invention provides indole derivatives of the general formula: ##STR1## wherein R1 is a hydrogen atom or an alkyl, alkenyl, cycloalkyl, cycloalkenyl, carboxyl, cyano, alkylcarbonyl,...
4849435 Fungicidal 1-aminomethyl-3-aryl-4-cyano-pyrroles  
Fungicidally active novel 1-aminomethyl-3-aryl-4-cyanopyrroles of the formula ##STR1## in which Ar represents optionally substituted phenyl, R represents a ##STR2## or ##STR3## radical, R1...
4847301 Methods of use of α-(aminoalkyl)-arylacetic acid derivatives  
Novel α-aryl-α-(ω-aminoalkyl)-α-[hydroxy(aralkyl and cycloalkyl)]acetic acid derivatives and α-aryl-α-(ω-aminoalkyl)-α[alkanoyloxy(aralkyl and cycloalkyl)]acetic acid derivatives, such as...
4839377 5-substituted 3-aminoalkyl indoles  
Compounds are disclosed of general formula (I) ##STR1## wherein R1 represents a group CHO, COR8, CO2 R8, CONR9 R10, CSNR9 R10 or SO2 NR9 R10, where R8 represents an alkyl, cycloalkyl, aryl or...
4808582 New cinnamoic compounds, the process for preparing same and the use thereof in therapeutics  
Compounds of formula: ##STR1## wherein: Ar is an aromatic group; R and R1 are H or CH3 ; A represents a nitrogenized heterocyclic radical; B is OH or forms with the adjacent CO group, either an...
4792555 Phospholipase A2 inhibitors  
There are disclosed compounds of the formula ##STR1## wherein R1 is lower alkyl, lower alkoxycarbonyl lower alkyl, aralkoxycarbonyl, aralkoxycarbonyl lower alkyl or indol-2-yllower alkyl; R2 is...
4788191 1,3-dithiolano-, 1,4-dithiino- and 1,4-dithiepino[2,3-C]pyrrole derivatives, their production and use  
The compound of the formula ##STR1## wherein X is a cyclic group which may optionally be substituted; Y is a carboxyl group which may optionally be esterified or amidated; Z is --CHCH--CHCH--,...
4785016 Indole derivatives  
Indole derivatives are disclosed of formula (I): ##STR1## wherein R1 represents H, alkyl or alkenyl; R2 represents H, alkyl, alkenyl, cycloalkyl or phenyl or phenyl alkyl the phenyl ring being...
4777179 Heterocyclic derivatives, processes for the use thereof and pharmaceutical compositions containing them  
The invention provides compounds of the general formula ##STR1## and physiologically acceptable salts and hydrates thereof, in which one of R1 and R2 represents hydrogen, halogen or a C1-4 alkyl...
4777168 Bicyclic benzo-oxy heterocyclic ethers and thioethers, pharmaceutical compositions and use  
A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting parmacological activity, including anti-secretory and anti-ulcerogenic activity, pharaceutical compositions...
4760061 Ether and ester derivatives of phenols  
Mono- or bis-complex esters or ethers of a phenol derivative of the formula NU--A--X--R1wherein NU is a defined mono- or bis-phenolic nucleus including a hydroxyphenyl-hydroxynaphthyl;...
4656180 Diamine derivatives and pharmaceutical preparations containing these compounds  
Diamine derivatives corresponding to the general formula I R1 R2 N--(CH2)m --Q--A--NH--R--NH--B--Q'--(CH2)n NR3 R4 (I)which have a highly selective action on histamine-H2 receptors and are...
4650810 Indole-5-acetamides for treatment of migraine  
Compounds are disclosed of general formula (I): ##STR1## wherein R1, R3, R4, R6 and R7, which may be the same or different, each represents a hydrogen atom or an alkyl group; R2 represents a...
4636521 3 amino alkyl indoles for use in treating migraine  
Compounds are disclosed of general formula (I) ##STR1## wherein R1 represents an alkyl, cycloalkyl, aryl or aralkyl group; R2, R3, R4, R6 and R7, which may be the same or different, each...
4621097 Saturated cycloalkyl[c] pyrrole-2(1H)-acetic acid amides and derivatives thereof  
A unique series of saturated cycloalkyl[c]-pyrrol-2(1H)-acetic acid amides are useful as agents for the reversal of amnesia. Intermediates for preparing the compounds, pharmaceutical composition...
4616009 Neuroleptic indole-3-carboxamide derivatives  
Indole-3-carboxamide derivatives of the formula: ##STR1## inclusive of pharmaceutically acceptable acid addition salt and/or hydrate forms thereof, wherein R1 is hydrogen, C1-4 alkyl, phenyl which...
4614739 Oxindole derivatives, pharmaceutical compositions and use  
Oxindole derivatives of the general formula I ##STR1## are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in...
4590189 Condensed pyrrolinone derivatives, their production and use  
The compound of the formula ##STR1## wherein X is a cyclic group which may optionally be substituted; Y is a carboxyl group which may optionally be esterified or amidated; Z is --CHCH--CHCH--,...
4581355 3-indolecarboxamides for control of circulatory diseases  
3-Indolecarboxamide compounds of the formula: ##STR1## inclusive of pharmaceutically acceptable acid addition salt and/or hydrate forms thereof, wherein R1 is hydrogen or C1-4 alkyl; each of R2...
4576940 Anti-allergic 3-indolecarboxamides  
3-Indolecarboxamide compounds of the formula: ##STR1## inclusive of pharmaceutically acceptable acid addition salt and/or hydrate forms thereof, wherein R1 is C1-8 alkyl, C3-8 cycloalkyl, C3-8...
4546099 N-Aminomethyl-3-phenyl-4-cyanopyrrole derivatives, compositions and use thereof as microbicides  
The invention relates to novel N-aminomethyl-3-phenyl-4-cyanopyrrole derivatives of the formula I ##STR1## wherein R1 and R2 are each independently hydrogen, halogen, methoxy or methylthio, Z is a...
4505921 Sulfonylurea compounds and their use in treating diabetes  
New sulfonylurea compounds of the formula: ##STR1## in which n is 1 or 2, R is thienyl, furyl, pyridyl or phenyl optionally mono or disubstituted, R1 and R2, the same or different, each are...
4487769 Amidines  
Mitomycin A, mitomycin C, and porfiromycin react with amide acetals and other amide derivatives to produce amidine derivatives having antitumor activity against experimental animal tumors. The...
4482549 Aminocyclopentane esters and pharmaceutical formulation  
Compounds are described of the formula ##STR1## in which --COR1 is a complex ester or thioester group, W is alkylene, X is cis or trans --CHCH or --CH2 CH2 --, n is 1 or 2, Y is a saturated...
4479963 1-Carboxyalkanoylindoline-2-carboxylic acids  
1-Carboxy-(alkanoyl or aralkanoyl)-indoline-2-carboxylic acids, e.g., those of the formula ##STR1## R=H, alkyl, alkoxy, halogeno or CF3 ; R'=H or R-phenyl; m=0 or 1; p,q=0 to 2;and derivatives...
4474778 Lactam containing compounds, their pharmaceutical compositions and method of use  
Compounds of the formula ##STR1## are disclosed wherein R is ##STR2## The compounds possess hypotensive activity.
4454131 Thiophene derivatives  
This invention relates to new thiophene derivatives and their use as fungicides in agriculture and horticulture.
4414220 Organic diamine therapeutic compositions  
A series of organic diamine base compounds derived from either an aromatic, alicyclic or heterocyclic ring and possessing, for the most part, an intervening methylene group between the ring and...
4412994 Mannich-base hydroxamic acid prodrugs, compositions and use  
Novel prodrug forms of known non-steroidal anti-inflammatory agents are disclosed, said prodrugs having the structural formula ##STR1##
4374846 N-Amino alkyl indole compounds compositions containing same, and a method of using same in therapy of disorders of gastrointestinal motility  
Novel N-amino alkyl indole compounds are disclosed. These compounds correspond to the Formula I ##STR1## In said Formula R1 indicates the hydrogen atom, an alkyl group with 1 to 4 carbon atoms,...
4370342 S-Alkyl 3-alkylthiopropionothioate compounds, their production and their medicinal use  
The invention relates to S-alkyl 3-alkylthiopropionothioates of Formula (I) as defined herein. Also included in the invention are methods for the manufacture of said S-alkylthiopropionothioates,...
4366164 Amine derivatives  
The invention provides compounds of general formula ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which Y and Z, which may be the same or different, each...
4325940 Anti-microbial, cosmetic and water-treating ionene polymeric compounds  
The use for anti-microbial, cosmetic and water-treatment of compounds of formula: ##STR1## in which RI and RII and (I) the same or different monovalent, branched or unbranched, alkyl groups of...
4284632 3-Pyrrolin-2-one derivatives and compositions  
New 3-cyclicaminoalkoxy-4-phenyl-3-pyrrolin-2-ones are disclosed. These compounds exhibit anti-hypertensive and vasodilatory action.
4272533 N-Phenylindoline derivatives, and pharmaceutical compositions containing them  
2-aminoethyl-1-phenylindolines are useful as anti-diabetic and anti-obesity agents.
4252803 Indole compounds and use thereof  
Compounds are disclosed of general formula (I): ##STR1## wherein R1 and R2 each independently represents a hydrogen atom, or an aryl, aralkyl, cycloalkyl, fluoroalkyl or alkyl group, which alkyl...
4241080 Stabilized aqueous antimicrobial composition  
Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene...
4235896 Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same  
Compounds of the formula ##STR1## in which A is lower alkyl, or a substituted or unsubstituted phenyl, thienyl, furyl, indolyl or thiaindolyl radical, R, X4 and X5 are hydrogen or lower alkyl, Y...
4232041 Aqueous antimicrobial composition having improved stability  
Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene...
4221789 Lactam-N-acetic acids and their amides  
New lactam-N-acetic acids and amides thereof having the formula ##STR1## wherein R1 and R2 =H, C1 -C4 -alkyl, aryl or halogen-substituted aryl, R3 =OH or --NR4 R5, R4 and R5 =H, C1 -C4 -alkyl,...
4190668 Stabilized aqueous amide antimicrobial composition  
Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene...
4153702 Basically alkylated dithiosalicyclic acid amides and their use as medicaments  
The invention provides novel antithrombotics diphenyl-disulphide-2,2'-bis-carboxylic acid amides of the general formula ##STR1## in which R1 represents a hydrogen or halogen atom or an optionally...
4146624 Method of treating viruses with bis-basic ketones of dibenzofuran  
Antiviral compositions and methods of inhibiting or inactivating viruses by administering to hosts an effective quantity of an active ingredient are disclosed herein. The active ingredients are...
4139634 Indole derivatives and process for preparing the same  
Indole derivatives of the formula: ##STR1## wherein R1 represents a hydrogen atom or a methyl radical, R2 and R3, which are the same or different, each represent a hydrogen atom, a methyl or ethyl...
4091113 Randomly terminated capped polymers  
Anti-microbial polymeric quaternary ammonium compounds and mixtures thereof, having linear chains which terminate in quaternary ammonium moieties, such compounds being formed by polymerization...
4055712 Method of preparing capped polymers  
A method of inhibiting the growth of microorganisms which comprises applying thereto microbiocidal quaternary ammonium polymers which are made by condensing a difunctional tertiary amine with an...
4051242 Substituted N-acyl-N"-(3-amino-2-cyanoacryloyl-)formamidrazones  
Therapeutically-active and pharmacologically-acceptable N-acyl-N" -(3-amino-2-cyanoacryloyl)-formamidrazones and their pharmaceutically-acceptable acid-addition salts inhibit xanthine oxidase and...
4038400 Method of treating conditions of delayed hypersensitivity using bis-basic substituted acenaphthene derivatives  
Novel 3,6-bis basic ketone derivatives of acenaphthene useful in treating conditions of delayed hypersensitivity are disclosed.

Matches 151 - 200 out of 209 < 1 2 3 4 5 >