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8124587 |
2-(aminomethyl)-5-chlorobenzylamide derivatives and their use as inhibitors of the clotting factor Xa
2-(Aminomethyl)-5-chlorobenzylamide derivatives and their use as inhibitors of coagulation factor Xa are provided. The compounds are suitable for the treatment and prophylaxis of cardiovascular and...
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8075922 |
Method of co-infusing a deoxygenated hemoglobin containing blood substitute and inorganic nitrite
Contrary to current opinion that nitrite in general oxidizes hemoglobin with elimination of active nitric oxide, deoxygenated hemoglobin reacts with low concentration inorganic nitrite to produce...
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8034777 |
Modified anticholinergic neurotoxins as modulators of the autoimmune reaction
The invention comprises a composition of matter and method of its use for the treatment of multiple sclerosis in humans. The composition is a modified anticholinergic alpha-neurotoxin....
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8034367 |
Tissue adhering compositions
A method mixes a first component, a second component, and a buffer material. The first component includes an electrophilic polymer material comprising poly(ethylene glycol) having a functionality...
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8030281 |
Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles...
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7943576 |
Methods of using enterostatin as inhibitor of angiogenesis
It has been discovered that enterostatin inhibits angiogenesis in an in vitro adipose tissue angiogenesis model. In concentrations from about 10−6 to about 10−9 M, enterostatin effectively blo...
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7846487 |
Biologically active products
The present invention relates to dehydrated Type II collagen containing cartilage which has retained the collagen in its original crosslinked structure and which contains at least 40% by weight of...
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7833522 |
Apparatus and method to treat a wound area
A method is disclosed to treat a patient having a wound area, such as a burn injury. The method provides a plurality of epidermal/dermal cells, and applies that plurality of epidermal/dermal cells...
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7833973 |
Pharmaceutical formulations for reducing pain
The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in...
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7829126 |
Infant formulas containing docosahexaenoic acid and lutein
Disclosed are infant formulas and corresponding methods of using them to promote retinal health and vision development in infants. The formulas, which are free of egg phospholipids and comprise...
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7781158 |
Method of separating collagen from the various animal tissues for producing collagen solution and product using the same
A method for separation the collagen from the various animal tissues is disclosed for preparing collagen solution and product using the same. The porcine tissues are processed to have proper form...
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7381706 |
Gonadotropin-releasing hormone, precursor peptides thereof and genes encoding the same
A novel peptide found as gonadotropin-releasing hormone (GnRH) in octopuses, a member of mollusks. The structure and the activities of the peptide have been unraveled. The peptide finds use as a...
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7335636 |
SPRR1A and axonal regeneration
The present invention provides polynucleotides, polypeptides, pharmaceutical compositions, and methods for modulation of nerve growth and regeneration.
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7238661 |
Oral lactoferrin in the treatment of respiratory disorders
The present invention relates to methods of treating an allergic or non-allergic respiratory disorder by administering orally a composition of lactoferrin alone or in combination with metal...
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7196057 |
Fusion proteins for insect control
A fusion protein comprising a translocating moiety and a toxic moiety wherein the translocating moiety comprises a plant protein that is capable of acting as a carrier to translocate the toxic...
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7166570 |
Medical implants and fibrosis-inducing agents
Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the...
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7156881 |
Counteracting bioprosthetic calcification
Adapting crosslinking with triglycidyl amine (TGA) to incorporate the use of a particular type of anti-calcification agent provides a broad-reaching solution to the problem in vivo bioprosthesis...
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7125848 |
Methods of treating non-inflammatory gastrointestinal tract disorders using Cav2.2 subunit calcium channel modulators
A method is provided for using Cav2.2 subunit calcium channel modulators to treat non-inflammatory gastrointestinal tract disorders.
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7087577 |
Method of promoting natural bypass
An angiogenic factor comprising a mixture of proteins derived from bone. The angiogenic protein mixture is produced by a series of steps that allow the proteins to be kept in solution. The...
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7078376 |
Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects
The invention discloses several novel therapeutic properties and methods of treatment using the recombinant erythropoietin prepared by expression from the Apa I restriction fragment of human...
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7041648 |
Compositions and methods for treating female fertility
The PTX3 gene or equivalent PTX3 activity is required for female fertility. Manipulation of PTX3 activity will regulate female fertility. The effects of female sterility may be ameliorated,...
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7026287 |
Lectins as anti-fibrotic agents
The subject invention is directed to the treatment of tissue fibrosis by administration of an effective amount of lectin. Fibrosis herein refers to the accumulation of extracellular matrix...
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7015198 |
Materials for soft tissue augmentation and methods of making and using same
Materials for soft tissue augmentation in mammals are prepared by cross-linking blood plasma proteins, preferably with a zero-length cross-linking agent. The cross-linked blood plasma proteins can...
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7005414 |
Synthetic oxygen transport made from cross-linked modified human or porcine haemoglobin with improved properties, method for a preparation thereof from purified material and use thereof
According to the claims, the present invention comprises the preparation of chemically modified, cross-linked hemoglobins with improved functional properties, the cross-linked hemoglobins prepared...
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7001882 |
Muteins of bilin-binding protein
The present invention relates to muteins of the bilin-binding protein with binding activity to digoxigenin and to fusion proteins of such muteins, a method for preparing said muteins and fusion...
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6998389 |
Pharmaceutical composition comprised of spider venoms, the production thereof, and its use for treating tumor diseases
The present invention describes pharmaceutically effective substances from the poison of spiders of the family of Sicariidae as well as their preparation and their use in medicine.
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6998388 |
High density lipoprotein against organ dysfunction following haemorrhagic shock
Use of high density lipoprotein and/or derivatives in the manufacture of a medicament for the prevention or treatment of organ dysfunction following ischaemia and reperfusion injury. In particular,...
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6995137 |
Water-soluble natural film and its preparing method
The present invention relates to water-soluble natural film and its preparing method. More particularly, the present invention relates to water-soluble natural film manufactured by dissolving as an...
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6984628 |
Ophthalmic compositions comprising trefoil factor family peptides
This invention relates to compositions comprising trefoil family factor peptides which are useful in preventing or treating dry eye by topical administration of the composition to eye of the...
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6969525 |
Surgically implanted time release medication for post-surgical treatment of a patient
A method of administering a medication to a post operative patient with the medication being administered at the site of a surgery performed on the patient. The medication is formed into a time...
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6942663 |
Laser treatment of cutaneous vascular lesions
Methods for treating maladies such as cutaneous vascular lesions. A patient in need of vascular lesion treatment is identified. A hyperosmotic agent is administered to a region adjacent the lesion....
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6930093 |
Use of ribofuranose derivatives against inflammatory bowel diseases
A method for the prophylaxis or treatment of an inflammatory bowel disease is provided, comprising administering to a patient having or at risk of developing an inflammatory bowel disease a...
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6927207 |
Recombinant mistletoe lectines
The present invention relates to isolated mistletoe lectin polypeptides and the pharmaceutical composition comprising the polypeptides thereof. Also, the present invention relates to processes for...
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6887850 |
Method to provide nutritional composition
A method is described to provide composition for a nutritional supplement for convalescing patients recovering from illness or surgery, those with limited appetite such as the elderly, children or...
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6884773 |
Modified hemoglobins, including nitrosylhemoglobins, and uses thereof
Diseases which can be ameliorated by delivery of NO to tissues affected by the disease can be treated by administration of nitrosyl-heme-containing donors of NO, including nitrosylhemoglobin....
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6867182 |
Composition of a polypeptide and an amphiphilic compound in an ionic complex and the use thereof
A water-soluble composition containing a complex of an ionic pharmaceutically effective interleukin, characterized in that said composition contains, in addition, an amphiphilic compound, said...
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6852700 |
Colostrinin, and uses thereof
The use of Colostrinin as a medicament, particularly in the treatment of chronic disorders of the central nervous system and the immune system.
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6838440 |
Kolla2-desiccated avian sternal cartilage powder
Kolla2 powder compositions, method of preparing the compositions and use of the compositions in treating arthritic joint cartilage diseases. The compositions are orally administered to human in...
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6835715 |
Mammalian dihydroouabain-like factor and therapeutic compositions
A novel mammalian dihydroouabain-like factor is disclosed which substantially fails to cross-react with mammalian ouabain-like factor (OLF) for binding to anti-OLF antibody, but cross-reacts with...
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6827930 |
System for attracting fish
A sport fishing system having: a rod and reel, including fishing line; at least one fishing lure or natural bait; and a controlled released fish attractant for applying to the fishing lure or...
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6815427 |
Sericin-containing material, process for producing the same method of using the same
The object of the present invention is to elucidate a biologically active function of a component constituting undegraded sericin and to provide a novel medical material, cosmetic material, etc....
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6815417 |
Method for treating obesity and for inhibiting adipocyte activity
A method for treating obesity includes administering to humans or animals a pharmaceutically effective amount of stanniocalcin in the form of a pharmaceutical composition. Stanniocalcin has an...
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6809076 |
Use of anticoagulant agents in the extracorporeal treatment of blood
The present invention relates to the use of anticoagulant agents for the treatment of individuals with extracorporeal circulation as anticoagulant during the extracorporeal circulation and for...
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6800609 |
Isolated peptide of the horny layer and user thereof
The invention concerns an isolated polypeptide, of the family of calcium-fixing proteins, a mixture of polypeptides derived from proteolysis of the isolated polypeptide, compositions containing...
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6794360 |
Treatment of allergic rhinitis
The invention relates to the discovery that various proteins isolated from ticks are effective in the treatment and prevention of allergic rhinitis. These proteins may most suitably be applied to...
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6730323 |
Microclysmic gel for treatment of tissue trauma and burns
A therapeutic wound gel is provided which will enhance healing of the wound and reduce swelling and increase elasticity of the skin. Humatrix is bacteriostatic protectant with no bacteriocidal...
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6703360 |
Compositions and methods related to canine IgG and canine IL-13 receptors
The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R. In particular, the present...
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6667292 |
Nitric monoxide metabolite-polyoxyalkylene-hemoglobin complex
Disclosed is a nitric monoxide metabolite-polyoxyalkylene-hemoglobin complex having a molecular weight of from 100,000 to 2,000,000 daltons, in which a polyoxyalkylene derivative is bound to from...
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6656474 |
Methods of using a neurotrophin and its analogues for the treatment of gastrointestinal hypomotility disorders
The present invention relates to methods for enhancing gastrointestinal motility. In particular, the invention relates to the use of neurotrophin-3 and its analogues for enhancing gastrointestinal...
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6656903 |
Baby food stimulating growth of the thymus
A thymus growth stimulating baby food is provided, substantially composed of a fat component, as well as a carbohydrate component and a protein component of animal or vegetable or animal and...
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