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6255278 Composition containing pooled transferrins as an active principle for the induction of immune tolerance against antigens  
A method for controlling immune reactions to a foreign tissue or a foreign cell in a recipient host mammal to enhance tolerance of the recipient host mammal towards a grafted foreign tissue or a...
6255279 Cosmetic preparations containing vertebrate proteins and having antibacterial, antimycotical and antiviral action  
A peptide which is a monomer, homodimer, heterodimer, homotrimer, heterotrimer, homotetramer or heterotetramer, and is based on the following amino acid sequence: TBL Gly Ile Gly Asp Pro...
6255283 Use of proteins extractable from animal organs for the preparation of medicaments for the treatment of pathological conditions characterized by hyperproduction of tumor necrosis factor (TNF)  
Proteins extractable with perchloric acid from mammal liver, in particular from goat liver, are capable of lowering blood levels of Tumor Necrosis Factor (TNF) and can be used for the treatment of...
6248365 Use of complement inhibitors for the preparation of a pharmaceutical for the prophylaxis and therapy of inflammatory intestinal and skin disorders as well as purpura  
The invention relates to the use of complement inhibitors, especially of C1 inactivator or of factors I or H, for the preparation of a pharmaceutical and for the prophylaxis and therapy of chronic...
6248587 Method for promoting mesenchymal stem and lineage-specific cell proliferation  
The present invention fulfills a need in the art for methods that promote hematopoietic and mesenchymal stem and lineage-specific cell proliferation and differentiation by growth in the presence of...
RE37224 Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and adjuvant  
A vaccine for the immunocontraception of mammals is described. The vaccine consists of zona pellucida antigens and an adjuvant encapsulated in a liposome delivery system. The liposome delivery...
6242255 Protein which induces interferon-gamma production by immunocompetent cell  
A protein of human cell origin, which induces the IFN-γ production by immunocompetent cells and has the amino acid sequence of SEQ ID NO:1 near or at the N-terminus. It can be produced from human...
6238706 Method of stimulating growth in aquatic animals using growth hormones  
A method of administering growth hormone includes (a) osmotically shocking aquatic animals for about 60 seconds with a hyperosmotic salt solution; and (b) placing the shocked aquatic animals in a...
6239137 Salts of aminoimidazole carboxamide and 5 amino or substituted amino 1,2,3-triazole, induce apoptosis, inhibit DNA synthesis and control cyclooxygenase activity  
Compositions and methods are described for the induction of apoptosis inhibition of DNA synthesis, and/or inhibiting COX-2 activity using an effective amount of salts of aminoimidazole carboxamide,...
6238665 Anti-edema agent  
A pharmaceutical composition comprising a pharmaceutically effective amount of histamine-added immunoglobulin substantially suppresses edema formation and an increase of vascular permeability of...
6235719 Uses of compositions with α-lactalbumin base  
The invention concerns novel uses of α-lactalbumen and compositions containing it, as nutritional complement and as medicine, for regulating sleep and the biological clock controlling the...
6231850 Canine interleukin 12  
Canine interleukin 12 and a method for producing it by genetic engineering are disclosed. The canine interleukin 12 includes a protein having an amino acid sequence substantially the same as SEQ ID...
6228839 Use of keratinocyte growth factor to improve oxidative status  
The present disclosure provides methods for minimizing oxidative damage in an animal or human during or after malnutrition, underfeeding or fasting, especially during refeeding after undernutrition...
6224871 Dietary supplement for nutritionally promoting healthy joint function  
A dietary supplement for nutritionally promoting healthy joint function in human subjects is disclosed. The supplement includes as a major ingredient a protein derived from the enzymatic hydrolysis...
6221847 Composition and method for treating bacterial infection  
A method and composition for preventing and treating infection from clinically relevant bacterial isolates is disclosed. The composition contains an anti-bacterial agent that inhibits the growth of...
6221836 Composition of pyruvate and anabolic protein and method for increasing fat loss in a mammal  
The present invention is based in part upon the discovery that the use of pyruvate in enteral formulations, in combination with an anabolic protein composition, produces a synergistic effect in...
6221842 Method of treating muscular disorders  
The invention provides pharmaceutical compositions comprising particular isoforms of human insulin-like growth factor I (IGF-I). An isofoim of the invention is an IGF-I polypeptide corresponding to...
6217886 Materials and methods for making improved micelle compositions  
Provided are methods for preparing improved biologically active micelle and crystalline products comprising a biologically active amphipathic compound in association with a micelle or crystalline...
6218357 Fibroin fluid and process for the production thereof  
A fibroin fluid obtained by adding carbon dioxide to a fibroin aqueous solution and then completely removing the carbon dioxide by pressure reduction or heating has fibroin microstructures which...
6218360 Collagen based biomaterials and methods of preparation and use  
This invention comprises purified native state Type VI collagen/βig, Type VI-βig collagen gel, including the crosslinked gel, and the use of the gel in fibrosis limited wound healing, and methods...
6214572 Programmed cell death and ICH-3  
This invention relates to modulation of programmed cell death. It also relates to transgenic non-human animals comprising a disrupted Ich-3 gene and methods of making these animals. The Ich-3...
6211157 Protein mixtures to induce therapeutic angiogenesis  
An angiogenic factor comprising a mixture of proteins derived from bone. The angiogenic protein mixture is produced by a series of steps that allow the proteins to be kept in solution. The...
6207640 Treatment of partial growth hormone insensitivity syndrome  
Methods for increasing the growth rate of a human patient having partial growth hormone insensitivity syndrome, but not Laron syndrome, are described. One such method comprises administering an...
6207641 Pharmaceutical composition containing IFN-γ inducing polypeptide or factor for treating and/or preventing IFN-γ susceptive diseases  
An agent for susceptive diseases, which contains a polypeptide that has a molecular weight of 18,500±3,000 daltons on SDS-PAGE and a pI of 4.9±1.0 on chromatofocusing, strongly induces the IFN-γ...
6207200 Use of proteins as anti-retroviral agents  
The present invention relates to the discovery that a protein, having a molecular weight of about 14 Kd, extracted with perchloric acid from animal organs such as goat liver, has anti-retroviral...
6207159 Methods for the diagnosis and treatment of insulin-dependent diabetes mellitus  
Methods for detecting the status of an insulin-dependent diabetes mellitus (IDDM)-associated autoimmune response in a mammal are provided. Specifically, the ratio of the frequency of T helper 1...
6203816 Tissue factor based prothrombin time reagent  
The present disclosure relates to novel liposome compositions in which tissue factor is incorporated and methods for their preparation. The composition of the phospholipids in the liposomes has...
6200953 Relaxin analogs and derivatives compositions  
The present invention relates to a relaxin analogs and derivatives, and uses thereof. The present invention further relates to compositions comprising a relaxin analogs and derivatives, and relaxin...
6200587 Tissue sealant containing fibrinogen, thrombin and carboxymethyl cellulose or salt thereof  
A tissue sealant comprising thrombin, fibrinogen, and carboxylmethyl cellulose or an alkali metal or alkali earth metal salt thereof is disclosed. The tissue sealant of the present invention...
6197746 Method of using secretin for treating autism  
Secretin and secretin compositions are used for the treatment of autism and other neurological, behavioral and immunological disorders. The method includes administering an effective amount of...
6197751 Thymosin α1 promotes tissue repair, angiogenesis and cell migration  
The present invention relates to methods for promoting tissue repair, angiogenesis and cell migration. The method of the invention utilizes thymosin a1 (Tα1) peptide to promote tissue repair,...
6194379 Elemental enteral formula  
The present invention is directed to an elemental liquid nutritional product useful for providing nutrition to a patient having a malabsorption condition by enterally feeding to the patient a...
6187750 Method of hormone treatment for patients with symptoms consistent with multiple sclerosis  
A method for treating patients having symptoms consistent with multiple sclerosis comprising administering a regimen of doses of human growth hormone of less than 0.5 mg/day. In one aspect, the...
6183784 Method of ameliorating alimentary tract damage due to chemotherapy or radiation  
A milk product extract composiiton including a plurality of cell growth stimulating factors, extracted from milk product, in concentrated form; said factors having basic to approximately neutral...
6180601 Low molecular weight hyaluronic acid with peptide or protein  
The invention relates to freeze-dried soft, flexible and continous matrix of low-molecular weight hyaluronic acid or salt thereof, in which the molecular weight of the hyaluronic acid is preferably...
6180606 Compositions with enhanced osteogenic potential, methods for making the same and uses thereof  
Osteogenic compositions, and methods for preparing same, which compositions comprise a porous or semi-porous matrix, an osteogenic factor and an agent such as growth factors, nutrient factors,...
6180605 Composition with enhanced osteogenic potential, method for making the same and therapeutic uses thereof  
The present invention provides improved osteogenic compositions having enhanced by the sorption of growth factors, of nutrient factors, or drugs onto or into the compositions. Compositions may...
6177403 Compositions, methods, and apparatus for delivery of a macromolecular assembly to an extravascular tissue of an animal  
Compositions, methods, and an apparatus are provided for delivering a macromolecular assembly such as a plasmid, virus vector, or other gene vector, to an extravascular tissue such as muscle...
6177059 GPIb-lipid complex and uses thereof  
6174855 Pharmaceutical compositions comprising thrombin inhibitors and their use in the control of wound healing processes  
There is provided the use of a thrombin inhibitor in the manufacture of a product for use in the control of wound healing processes within the body, in particular, the inhibition or prevention of...
6174858 Conjugates useful in the treatment of prostate cancer  
Chemical conjugates which comprise oligopeptides, having amino acid sequences that are selectively proteolytically cleaved by free prostate specific antigen (PSA) and known cytotoxic agents are...
6171614 Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof  
The present invention provides glycophospholipid and peptide-phospholipid conjugates comprising a phospholipid moiety and a saccharide or peptide moiety joined by an ether linkage comprising a...
6172040 Immobilized lactoferrin antimicrobial agents and the use thereof  
Disclosed is a method for treating products, such as meat products, with immobilized lactoferrin to reduce microbial contamination. The lactoferrin is immobilized on a naturally occurring...
6172038 Antipathogenic peptides and compositions comprising them  
6168793 Heat shock protein 70 preparations in vaccination against cancer and infectious disease  
The present invention relates to compositions comprising a population of non-covalent heat shock protein 70-peptide complexes purified from mammalian tumor tissues or mammalian cells infected with...
6165982 Use of sericin as antioxidants and tyrosinase inhibitors  
This invention relates to a composition useful as an antioxidant or an inhibitor for tyrosinase activity which comprises as an active ingredient a sufficient amount of sericin to exert an...
6165496 Keratin-based sheet material for biomedical applications and method of production  
A sheet wound dressing formed of cross linked keratin. An insoluble, largely Beta keratin fraction from human hair is acidified to a low pH, preferably less than about 3, which partially...
6165983 Use of collagen for the treatment of degenerative articular processes  
The invention relates to the use of collagen for the production of a drug for the treatment of degenerative articular processes. An injection suspension is preferably produced, which contains...
6165981 Stabilizing solutions for proteins and peptides  
Disclosed are compositions for stabilizing proteins and fragments of the proteins. The composition contains buffer, salt, reducing agents, chelating agents and stabilizing proteins. The composition...
6162788 Uses of BPI protein products  
The present invention relates to methods for treating chlamydial infection comprising administering to a subject suffering from a chlamydial infection a bactericidal/permeability-inducing (BPI)...