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7365047 |
Use of pentagastrin to inhibit gastric acid secretion or as a diuretic
This invention pertains to the discovery that pentagastrin, when administered in conjunction with a proton pump inhibitor (PPI) is synergistic with the PPI and significantly increases the efficacy...
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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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6946477 |
3-Substituted piperidines comprising urea functionality, and methods of use thereof
One aspect of the present invention relates to novel heterocyclic compounds comprising urea functionality. A second aspect of the present invention relates to the use of the novel heterocyclic...
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6833389 |
Use of thiamphenicol and derivatives thereof for the preparation of pharmaceutical compositions useful in the treatment of Chlamydia pneumoniae infections
Use of thiamphenicol and derivatives thereof for the preparation of pharmaceutical compositions useful for the treatment Chlamydia pneumoniae infections is described.
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6743440 |
Polycyclic quinone and ionophore composition for the synergistic reduction of methane formation in ruminant animals
A composition, preferably used to reduce methane formation in a ruminant, wherein the composition is a combination of a polycyclic quinone compound and an ionophore compound.
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6627625 |
Treatment of behavioral disorders with β-lactam compounds
Administration of β-lactam compounds including β-lactam antibiotics and β-lactamase inhibitors provides significant neurotropic effects in warm-blooded vertebrates evidenced inter alia by...
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6599892 |
7-alkylidene cephalosporanic acid derivatives and methods of using the same
Derivatives of 7-alkylidene cephalosporanic acid sulfone and the pharmaceutically active salts thereof are found to be potent inhibitors of β-lactamase enzymes.
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6537985 |
Antibiotic formulation and a method of making this formulation
An antibiotic formulation in a true solution is provided. This formulation includes an antibiotic and N-methyl-2-pyrrolidone. It also may include a preservative, an antioxidant, and/or an additive....
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6492354 |
Soluble forms of amoxicillin and treatment of animals
A solid mixture or aqueous solution of amoxicillin antibacterial agent with a material that aids in its dissolution in water to render it ingestive and palatable.
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6461607 |
Probiotic, lactic acid-producing bacteria and uses thereof
The present invention discloses compositions and methodologies for the utilization of probiotic organisms in therapeutic compositions. More specifically, the present invention relates to the...
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6429191 |
Treatment of hearing impairments
Compositions and methods are provided for prophylactic or therapeutic treatment of a mammal for hearing impairments involving neuronal damage, loss, or degeneration, preferably of spinal ganglion...
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6316015 |
Hyperbactericidal surfaces
A surface is provided with antibiotic or antiseptic properties. A solid substrate is modified by covalently fixing one or more spacers having reactive extremities via a proximate reactive...
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6303644 |
Proton pump inhibitor in therapeutic combination with antibacterial substances
The invention relates to the use of proton pump inhibitors as combination therapeutics in the treatment of bacterial diseases which do not affect the gastrointestinal track using antibacterially...
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6221859 |
Carbapenem antibacterial compositions and methods of the treatment
The present invention relates to novel 2-(naphthosultamyl)methyl-carbapenem antibacterial agents or pharmaceutically acceptable salts thereof in combination with other β-lactams, which are useful...
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6187768 |
Kit for flushing medical devices and method of preparation
A kit and for flushing a medical device a method of preparing the kit is disclosed. The kit includes a container containing a mixed solution a unit dose of a pharmacologically effective amount of...
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6159706 |
Application of enzyme prodrugs as anti-infective agents
The present invention provides a method for targeting toxic antimetabolites to gram negative infections. It provides a means of taking advantage of a key disease resistance mechanism to activate...
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6143742 |
Treatment for necrotizing infections
The treatment of for arresting the destructive effects of proteolytic enzymes produced by a host infecting organism, such as "flesh eating bacteria", is carried out using therapy with includes the...
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6127355 |
High molecular weight polymer-based prodrugs
The present invention is directed compositions of the formula: ##STR1## wherein: D is a residue of a biologically active moiety; X is an electron withdrawing group; Y and Y' are independently...
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6093414 |
Silver-based antimicrobial compositions
The present invention relates generally to silver-based antimicrobial compositions and processes for making such compositions. More particularly, the present invention describes stable, purified...
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6051604 |
Methods and compositions for the prevention and treatment of gastrointestinal disorders
The subject invention encompasses methods for prevention and treatment of a human or lower animal subject having a gastrointestinal disorder caused or mediated by one or more intestinal helminths...
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5972309 |
Identification of an exogenous intra-erythrocytic bacterium in patients having systemic lupus erythematosus, and treatment
Intra-erythrocytic exogenous bacterial structures or parasites seen by giemsa and phase contrast microscopy in several patients with systemic lupus erythematosus (SLE) and not in controls were...
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5948422 |
Oral dosage-forms containing a β-lactam antibiotic
A granulate, containing at least 50 wt. % of a water soluble β-lactam antibiotic, is provided. A process to prepare a granulate containing such β-lactam antibiotic comprises moistening components...
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5935603 |
Water soluble powder form compositions and their applications thereof
Water soluble, powder form compositions suitable for completely and rapidly dissolving active ingredients which usually only dissolve in water in the presence of base salts, such as antibiotics of...
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5883074 |
Potentiators of antibacterial agents
Methods for screening for compounds which potentiate the activity of antibacterial agents against bacteria resistant to the antibacterial agent alone, pharmaceutical compositions including such...
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5827543 |
Methods and compositions for the prevention and treatment of urogenital disorders
The subject invention encompasses methods for prevention and treatment of a human or lower animal subject having a urogenital disorder caused or mediated by one or more parasitic protozoa...
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5770585 |
Homogeneous water-in-perfluorochemical stable liquid dispersion for administration of a drug to the lung of an animal
This invention is directed to a homogenous water-in-perfluorochemical stable liquid dispersion for acceptable therapeutic administration of a drug to the lung of an animal. The dispersion includes...
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5712268 |
Compositions of tricyclic β-lactams and uses thereof
There are described pharmaceutical compositions comprising (a) compounds of the formula ##STR1## in which R signifies lower alkoxycarbonyl, lower alkoxy-carbonylamino, the acyl residue of an α-...
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5698577 |
Compositions of bicyclic β-lactams and uses thereof
There are described pharmaceutical compositions comprising (a) compounds of the formula ##STR1## in which R signifies lower alkoxycarbonyl, lower alkoxy-carbonylamino, the acyl residue of an α-...
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5698533 |
Ophthalmic pharmaceutical composition
A method of administering a drug to an eye including the steps of: (a) admixing a pharmaceutically acceptable hydrocarbonaceous semi-solid or oil which contains the drug with water at a temperature...
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5674858 |
Medicaments for treating gastrointestinal disorders
The use is described of both (i) ranitidine bismuth citrate and (ii) one or more Helicobacter pylori-inhibiting antibiotics in treating or preventing gastrointestinal disorders. Pharmaceutical...
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5643902 |
Veterinary treatment
A formulation comprising amoxycillin or a veterinarily acceptable derivative thereof, clavulanic acid or a veterinarily acceptable derivative thereof, and a veterinarily acceptable carrier is used...
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5633245 |
Inhibition of expression of beta-lactamase using esters of fatty acid alcohols
A class of chemical compounds comprising fatty acid ester derivatives used to inhibit beta-lactamase production by infectious bacteria. These inhibitors have been found to retard the resistance of...
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5633244 |
Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic
A synergistic pharmaceutical combination or composition is disclosed for the treatment of gastritis and peptic ulcer containing a therapeutic amount of a histamine H 2 receptor blocking agent,...
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5618564 |
Composition for the treatment of helicobacter pylori infection
The present invention is directed to a method for the treatment of Helicobacter pylori infection wherein a composition containing protease and an antibacterial agent as active ingredients, which...
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5484809 |
Prodrugs for oral administration containing taxol or substituted taxol covalently bound to a phospholipid
The oral delivery of many classes of drugs is facilitated by converting drugs having suitable functional groups to 1-O-alkyl-, 1-O-acyl-, 1-S-acyl, and 1-S-alkyl-sn-glycero-3-phosphate derivatives....
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5478819 |
Phospholipid composition and use thereof
A method of and composition for treating a Helicobacter pylori infection in a mammal. The method comprises administering to said mammal orally a therapeutically effective amount of a Helicobacter...
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5476669 |
Method for treatment of gastro intestinal disorders
A method is disclosed for preventing the recurrence of duodenal ulcer associated with Campylobacter pylori (Helicobacter pylori) infection in a patient suffering from duodenal ulcer disease...
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5411947 |
Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
The oral delivery of many classes of drugs is facilitated by converting drugs having suitable functional groups to 1-O-alkyl-, 1-O-acyl-, 1-S-acyl, and 1-S-alkyl-sn-glycero-3-phosphate derivatives....
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5312813 |
Biofilm reduction method
A method of killing microorganisms which form a biofilm on a tissue or implant surfaces in a patient, and which are refractory to a biocide at a dose which is effective to kill the microorganism in...
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5256684 |
Methods and compositions for the treatment of gastrointestinal disorders
Methods, for the treatment of humans and lower animal subjects having a gastrointestinal disorder, comprising administering bismuth and administering an antimicrobial. From about 50 to about 5000...
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5156842 |
Liquid suspension for oral administration
A non-aqueous pharmaceutical liquid suspension having improved bioavailability for oral administration comprises an active ingredient suspended in an edible, non-aqueous carrier vehicle such as an...
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5114929 |
Pharmaceutical formulation
An unpressurized container containing a palatable pharmaceutical formulation comprising a homogeneous, non-aqueous suspension of an orally active medicament, an edible oily vehicle, an edible...
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4994512 |
Poly-methine compounds, condensation polymer having a poly-methine compound admixed therein and shaped articles produced therefrom
Disclosed are poly-methine compounds having the formula: ##STR1## wherein R 1 is an unsubstituted or substituted alkoxycarbonyl, cycloalkoxycarbonyl or aryloxycarbonyl radical; an unsubstituted or...
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4803196 |
Pharmaceutical compositions containing β-lactam antibiotics
A solid pharmaceutical composition comprising one or more β-lactam antibiotics in acid or amphoteric form in association with at least one physiologically acceptable base in the presence of a...
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4760059 |
Rectal dosage form
The rectal absorption of the beta-lactam antibiotic ceftriaxone in a solid dosage form is enhanced with chenodeoxycholic acid or its sodium salt, in the presence of a carrier consisting of a...
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4732753 |
Suppository dosage form
Suppositories containing as the active substance a therapeutically effective amount of ceftriaxone, a pharmaceutically compatible salt thereof or a hydrate of one of these compounds, a stabilizer...
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4692441 |
Chorine esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.
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4608392 |
Method for producing a non greasy protective and emollient film on the skin
A composition for topical application to the skin contains, as a fatty product to provide a nongreasy protective and emollient film thereon, a polyether oligomer having the formula ##STR1## wherein...
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4594246 |
Pharmaceutically-acceptable amine salts of 6-β-halopenicillanic acids
This invention relates to penicillanic acid derviatives of the formula I ##STR1## in which X stands for chlorine, bromine or iodine, to pharmaceutically acceptable, non-toxic salts of the compounds...
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4560553 |
Use of eucalyptol for enhancing skin permeation of bio-affecting agents
Eucalyptol is used to enhance skin permeation of bio-affecting agents.
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