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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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6949521 |
Therapeutic azide compounds
Pharmaceutical prodrug compositions are provided comprising azide derivatives of drugs which are capable of being converted to the drug in vivo. Azide derivatives of drugs having amine, ketone and...
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6884784 |
Diagnosis and management of infection caused by chlamydia
The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae . The invention is based, in part, upon the...
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6709678 |
Easy to swallow oral medicament composition
An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance,...
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6706290 |
Methods for eradication of nanobacteria
Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The...
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6627625 |
Treatment of behavioral disorders with β-lactam compounds
Administration of β-lactam compounds including β-lactam antibiotics and β-lactamase inhibitors provides significant neurotropic effects in warm-blooded vertebrates evidenced inter alia by...
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6569839 |
Fast-acting pharmaceutical compositions and methods of use
A pharmaceutical composition comprising at least one local anesthetic, at least one anti-inflammatory agent and at least one antibiotic are disclosed. The local anesthetic has a peak effect no...
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6544991 |
Compositions and methods for treating bacterial infections
A composition having antibacterial activity is disclosed. More particularly, a mixture of an oxazolidinone compound, sulbactam, and ampicillin active agents, demonstrating activity against...
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6537985 |
Antibiotic formulation and a method of making this formulation
An antibiotic formulation in a true solution is provided. This formulation includes an antibiotic and N-methyl-2-pyrrolidone. It also may include a preservative, an antioxidant, and/or an additive....
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6514955 |
Multi-faceted method to repress reproduction of latent viruses in humans and animals
Disclosed are methods for repressing reproduction of latent viruses, such as HIV, in animals by the generally concurrent administration of (1) antioxidants including a glutathione agent; and (2) an...
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6429191 |
Treatment of hearing impairments
Compositions and methods are provided for prophylactic or therapeutic treatment of a mammal for hearing impairments involving neuronal damage, loss, or degeneration, preferably of spinal ganglion...
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6380181 |
Synthetic catechol derivatives, method for production and use thereof
Catechol derivatives of general formula (I) in which R 1 denotes O-acyl and R 2 represents amino acid residues in the 3- and/or 4-position function as siderophores and/or as biological...
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6316015 |
Hyperbactericidal surfaces
A surface is provided with antibiotic or antiseptic properties. A solid substrate is modified by covalently fixing one or more spacers having reactive extremities via a proximate reactive...
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6271212 |
Prodrug azide compositions and compounds
Pharmaceutical prodrug compositions are provided comprising azide derivatives of drugs which are capable of being converted to the drug in vivo. Azide derivatives of drugs having amine, ketone and...
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6238659 |
Agent for treating papilloma virus-positive malignant and premalignant lesions
The present invention relates to a preparation comprising a substance influencing the cellular redox state for treating papilloma virus-positive malignant lesions.
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6174876 |
Use of boswellic acid for treating brain tumors
The present invention relates to the use of pure boswellic acid, a physiologically acceptable salt, a derivative, a salt of said derivative or a vegetable preparation containing boswellic acid for...
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6156346 |
Urease-responsive delivery systems for diagnostic and therapeutic applications
A delivery system that releases a diagnostic marker or therapeutic agent in a manner sensitive to the concentration of urease in a physiological compartment, particularly the gastrointestinal...
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6013647 |
Benzoxazinedione derivatives, method of producing them and uses thereof
This invention relates to new benzoxazinedione derivatives corresponding to the formula I: ##STR1## wherein R 1 =H or carboxyalkyl, R 2 =H, alkyl or phenyl, and R 3 represents different acid...
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5994340 |
Azetidinone derivatives as β-lactamase inhibitors
New 2-oxo-1-azetidine sulfonic acid derivatives with an aminoalkyl substituted "anti" (E-isomer) oxyimino group in the acylamino substituent at the 3 position of the monobactam ring. These...
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5948422 |
Oral dosage-forms containing a β-lactam antibiotic
A granulate, containing at least 50 wt. % of a water soluble β-lactam antibiotic, is provided. A process to prepare a granulate containing such β-lactam antibiotic comprises moistening components...
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5883074 |
Potentiators of antibacterial agents
Methods for screening for compounds which potentiate the activity of antibacterial agents against bacteria resistant to the antibacterial agent alone, pharmaceutical compositions including such...
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5849797 |
D-β-lysylmethanediamine derivatives and preparation thereof
Now are provided (R)-3,6-diamino-N-(ω-aminoalkyl)-hexanamides which are novel compounds having the general formula (I): ##STR1## wherein n stands for 2-5, and which may be for example,...
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5712268 |
Compositions of tricyclic β-lactams and uses thereof
There are described pharmaceutical compositions comprising (a) compounds of the formula ##STR1## in which R signifies lower alkoxycarbonyl, lower alkoxy-carbonylamino, the acyl residue of an α-...
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5698577 |
Compositions of bicyclic β-lactams and uses thereof
There are described pharmaceutical compositions comprising (a) compounds of the formula ##STR1## in which R signifies lower alkoxycarbonyl, lower alkoxy-carbonylamino, the acyl residue of an α-...
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5698533 |
Ophthalmic pharmaceutical composition
A method of administering a drug to an eye including the steps of: (a) admixing a pharmaceutically acceptable hydrocarbonaceous semi-solid or oil which contains the drug with water at a temperature...
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5674858 |
Medicaments for treating gastrointestinal disorders
The use is described of both (i) ranitidine bismuth citrate and (ii) one or more Helicobacter pylori-inhibiting antibiotics in treating or preventing gastrointestinal disorders. Pharmaceutical...
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5650394 |
Use of urinastatin-like compounds to prevent premature delivery
The present invention provides a method of diagnosing and treating a pregnant female at risk for impending preterm delivery. The method comprises the step of diagnosing imminent preterm delivery by...
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5643902 |
Veterinary treatment
A formulation comprising amoxycillin or a veterinarily acceptable derivative thereof, clavulanic acid or a veterinarily acceptable derivative thereof, and a veterinarily acceptable carrier is used...
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5607671 |
Medical use, a medical method and a pharmaceutical preparation
The invention concerns medical use, a medical method and a pharmaceutical preparation. The invention allows the action of β-lactam antibiotics to be targeted and their side effects to be reduced...
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5599795 |
Method for treatment of idiopathic inflammatory bowel disease (IIBD)
A new method for the prevention and treatment of Idiopathic inflammatory Bowel Disease (IIBD), including Crohn's Disease and Ulcerative Colitis, in human patients is provided. The key steps include...
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5478819 |
Phospholipid composition and use thereof
A method of and composition for treating a Helicobacter pylori infection in a mammal. The method comprises administering to said mammal orally a therapeutically effective amount of a Helicobacter...
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5397778 |
Enteral formulations for treatment of inflammation and infection
The present invention features saponin containing enteral formulations for treatment of infection and inflammation. These saponin containing formulations are particularly useful in conjunction with...
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5312813 |
Biofilm reduction method
A method of killing microorganisms which form a biofilm on a tissue or implant surfaces in a patient, and which are refractory to a biocide at a dose which is effective to kill the microorganism in...
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5260292 |
Topical treatment of acne with aminopenicillins
A method and composition for topically treating acne and acneiform dermal disorders includes applying an amount of an antibiotic selected from the group consisting of ampicillin, amoxicillin, other...
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5256684 |
Methods and compositions for the treatment of gastrointestinal disorders
Methods, for the treatment of humans and lower animal subjects having a gastrointestinal disorder, comprising administering bismuth and administering an antimicrobial. From about 50 to about 5000...
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5114929 |
Pharmaceutical formulation
An unpressurized container containing a palatable pharmaceutical formulation comprising a homogeneous, non-aqueous suspension of an orally active medicament, an edible oily vehicle, an edible...
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5064823 |
Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers
Pentacyclic triterpenoid compounds such as α boswelic acid and its acetate, β-boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are...
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4898731 |
Antibiotic combinations of penicillins
An antibacterial synergistic composition consisting essentially of a mixture of a penicillin or cephalosporin derivative of the formula ##STR1## and a penicillin of the formula ##STR2## preferably...
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4898728 |
Process for production of composition containing lecithin and polyvinylpyrrolidone
A process for the production of a sterile composition containing lecithin and polyvinyl pyrrolidone is disclosed in which the lecithin and polyvinyl pyrrolidone, optionally with one or more...
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4803196 |
Pharmaceutical compositions containing β-lactam antibiotics
A solid pharmaceutical composition comprising one or more β-lactam antibiotics in acid or amphoteric form in association with at least one physiologically acceptable base in the presence of a...
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4760059 |
Rectal dosage form
The rectal absorption of the beta-lactam antibiotic ceftriaxone in a solid dosage form is enhanced with chenodeoxycholic acid or its sodium salt, in the presence of a carrier consisting of a...
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4732753 |
Suppository dosage form
Suppositories containing as the active substance a therapeutically effective amount of ceftriaxone, a pharmaceutically compatible salt thereof or a hydrate of one of these compounds, a stabilizer...
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4692441 |
Chorine esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.
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4594246 |
Pharmaceutically-acceptable amine salts of 6-β-halopenicillanic acids
This invention relates to penicillanic acid derviatives of the formula I ##STR1## in which X stands for chlorine, bromine or iodine, to pharmaceutically acceptable, non-toxic salts of the compounds...
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4521533 |
Salts of 6-alpha-(aminomethyl)penicillanic acid 1,1-dioxide esters and beta-lactam antibiotics
Salts of readily hydrolyzable esters of 6-alpha-(aminomethyl)penicillanic acid 1,1-dioxide and (a) prodrug forms of ampicillin and amoxicillin or (b) ampicillin and amoxicillin and a dibasic acid...
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4501734 |
Promotion of absorption of drugs administered through the alimentary system
An extract from a saponin-containing galenical has the effect of promoting absorption of a pharmacologically active substance or drug such as β-lactam antibiotic administered through the...
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4496587 |
Inhibition of bacterial toxin release by prostaglandins
The present invention provides a method for inhibiting the synthesis and release of toxins from bacteria which comprises contacting the bacteria with an antitoxic prostaglandin.
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4472374 |
Veterinary compositions for reducing mammary infections
An intramammary composition containing a siloxane elastomer with incorporated antibacterial agent. The composition is of sufficiently low viscosity to facilitate application to the teat of a cow...
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4470980 |
Method of increasing oral absorption of β-lactam antibiotics
A method and drug form are provided for increasing the oral absorption of β-lactam antibiotics such as the penicillins, cephalosporins and related chemical species by the oral administration of...
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4452796 |
6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
Beta-lactamase inhibitors which are 6-alpha- and 6-beta-(aminomethyl) and (1-aminoethyl)pencillanic acid 1,1-dioxides; pharmaceutically-acceptable salts thereof; conventional esters thereof which...
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