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8148360 |
Supramolecular metallic complexes exhibiting both DNA binding and photocleavage
Supramolecular complexes that target and cleave DNA are provided. The supramolecular complexes include at least one metal-to-ligand charge transfer (MLCT) light absorbing unit, at least one Pt...
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8071506 |
Synergistic herbicidal composition containing florasulam for weed control in turf
An herbicidal composition containing (a) florasulam and (b) at least one preemergent annual grass herbicide selected from the group consisting of dithiopyr and pendimethalin provides synergistic...
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8062677 |
Methods and compositions for the sustained release of chromium
Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the...
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8043422 |
Combinations of phenylpyrroles and pyrion compounds
The present invention relates to combinations of a phenylpyrrole, or a salt thereof, and a pyrion compound which provide an improved biocidal effect. More particularly, the present invention...
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8017599 |
Sequence selective pyrrole and imidazole polyamide metallocomplexes
The present invention relates to sequence selective compounds for targeting therapeutic or diagnostic groups to polynucleotides. More particularly, the present invention relates to sequence...
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7928097 |
Photoreactive compounds and compositions
The present invention provides a compound of formula (I): PtIV(N3)2X1X2Y1Y2, wherein X1 and X2 are the same or different and each one is a group NR1R2R3 wherein R1, R2 and R3 are the same or...
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7632827 |
Anti-cancer phosphine containing [AuIIIm(CNC)mL]n+ complexes and derivatives thereof and methods for treating cancer using such compositions
Gold(III) phosphine complexes [Aum(CNC)mL]n+ (where HCNCH=2,6-diphenylpyridine) and their use as anti-tumor agents are disclosed. Notable results for the appearance of new potential anti-tumor...
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7612057 |
Supramolecular complexes as photoactivated DNA cleavage agents
The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal...
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7544367 |
Chemical method of making a suspension, emulsion or dispersion of pyrithione particles
A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione...
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7481873 |
Small particle copper pyrithione
Disclosed herein is a composition comprising a non-dusting copper pyrithione dispersion comprising small solid particles of copper pyrithione dispersed in a liquid dispersant, said solid particles...
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7455851 |
Pyrithione biocides enhanced by silver, copper, or zinc ions
The present invention is directed to an antimicrobial composition, comprising pyrithione or a pyrithione complex; and a zinc or copper or silver source selected from the group consisting of zinc or...
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7429577 |
Augmentation of atypical antipsychotic agent pharmacotherapy with chromium supplementation
The present invention relates to pharmaceutical compositions comprising an antipsychotic agent in combination with a chromium salt, which are used for minimizing side effects in a patient taking an...
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7354771 |
Method of determining absolute configuration of chiral compound
The absolute configuration of a chiral compound is determined by (i) coordinating the chiral compound to a metalloporphyrin having a carbon chain-crosslinked porphyrin dimer structure in which one...
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7335651 |
Compositions incorporating(-)-hydroxycitric acid and related methods for promoting fat oxidation
Methods for promoting healthy body weight and improving a variety of related physiological factors, including serum serotonin levels, serum leptin levels, fat oxidation, cholesterol levels, and...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7300927 |
Method for treating or preventing Alzheimer's disease
Disclosed is a method for treating or preventing Alzheimer's disease by restricting the level of metabolizable carbohydrate in the diet and/or administering to the patient an effective amount of an...
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7271161 |
Platinum complexes as antitumor agents in combination with biochemical modulation
The present invention concerns the use of methods and compositions for the treatment of cancer and other hyperproliferative diseases. In certain embodiments, methods are described for the treatment...
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RE39480 |
Chromium/biotin treatment of type II diabetes
A method for treating Type II diabetes by administering to an affected individual a combination of chromic tripicolinate and biotin. The two compounds are administered orally or parenterally at in...
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7153877 |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and...
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7101868 |
Substituted arylamine derivatives and methods of use
Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically...
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7078059 |
Treatment of bone diseases
The invention provides a method for enhancing bone formation, inhibiting osteoclastic differentiation and/or activating osteoblastic differentiation whereby to manage, treat or achieve prophylaxis...
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7053079 |
Dihydroxy (3-pyridyl) borane compounds
A dihydroxy(3-pyridyl)borane compound of the formula (1): wherein R1 represents a hydrogen atom, halogen atom or alkoxycarbonylamino group; R2 represents a hydrogen atom, halogen atom, alkyl group...
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7026308 |
Topical anti-microbial compositions
Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed...
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7011854 |
Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases...
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6979681 |
Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer
Ruthenium (II) compounds of the formula: wherein: R1 is —CO2CH3; R2, R3, R4, R5 and R6 independently represent H, alkyl, cylcoalkyl, —CO2R′, aryl or alkylaryl, which latter two groups are optio...
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6958359 |
Vanadium compounds as anti-angiogenic agents
Vanadium compounds for inhibiting angiogenesis useful for treating or preventing diabetic retinopathy, hemangiomas, cancers with abnormal blood vessel supply, restenosis following vascular injury,...
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6955873 |
Diagnosis and treatment system for reward deficiency syndrome (RDS) and related behaviors
The present invention relates to a kit and an intervenously administrable preparation, both, with a signal transmitter precursor, an enhancer of precursor uptake, and an inhibitor of...
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6908912 |
Pyrithione biocides enhanced by zinc metal ions and organic amines
The present invention is directed to a stable, soluble, antimicrobial composition concentrate comprising pyrithione or a pyrithione complex in an amount of from about 0.5% to about 30 weight...
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6878388 |
Vanadium compounds for treating proliferative cell disorders
Vanadium compounds useful to prevent and/or inhibit adhesion, migration, and invasion of proliferative cells into surrounding tissue.
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6867217 |
Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade
The invention relates to substituted polycyclic aryl and heteroaryl pyridone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods...
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6849613 |
Multiple antioxidant micronutrients
A method for administering an antioxidant composition to humans according to their age and sex is disclosed wherein the method comprises administering to said humans a daily dose of a multiple...
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6846777 |
Synergistic biocidal composition
The invention relates to a biocidal composition which can be added to materials which can be attacked by harmful micro-organisms, containing pyrithione as a biocidal active ingredient. The biocidal...
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6835371 |
Diagnostic and therapeutic piperazine and piperidine compounds and process
Piperazine or piperidine compounds useful for treating neurodegenerated diseases characterized by the lack of dopamine neurons activity or for imaging the dopamine neurons are provided. The...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6812247 |
Organometallic complex
A metal complex and its use for binding or cleaving a nucleic acid. The metal complex has the formula: M is Pt, Pd, Ni, Co, or Cu; X is aryl, heteroaryl, cyclyl, or heterocyclyl; Y is halogen,...
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6777405 |
Detection and treatment of duplex polynucleotide damage
Duplex polynucleotides containing damage or errors are detected with hindered intercalating compounds which are capable of intercalating only in the presence of such damage or error. Conditions...
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6753016 |
Preservation of wood products
A method for the protection of wood and other wood materials without affecting dimensional stability or surface integrity of the treated material is described. The method involves treating wood...
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6743786 |
Vanadium compounds for treating cancer
The invention provides methods for treating cancer and compounds that are useful for the treatment of tumors, as well as pharmaceutical compositions comprising the compounds, and synthetic methods...
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6713469 |
Chromium picolinate compositions and uses thereof
Compositions comprising chromic tripicolinate or chromic polynicotinate in combination with at least one of a cyclooxygenase inhibitor, an acid, a mucolytic and a salicin-containing herb. The...
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6693094 |
Biguanide and sulfonylurea formulations for the prevention and treatment of insulin resistance and type 2 diabetes mellitus
The invention describes formulations that include either metformin, sulfonylurea or a biguanide-sulfonylurea combination as one active ingredient in addition to specific, other active ingredients....
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6689774 |
Zinc ionophores as therapeutic agents
The present invention provides methods and compositions comprising one or more zinc ionophores for protecting tissue from the harmful effects of apoptosis in patients in need thereof....
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6667339 |
Vanadium (IV) complexes containing catecholate ligand and having spermicidal activity
Vanadium (IV) complexes containing a substituted or unsubstituted catecholate ligand, and the spermicidal activity of such compounds. Preferred compounds are vanadocene (IV) complexes containing...
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6664248 |
2-nitromethylidene/2-cyanimino/2-nitro-imino-pyrrolidines and piperidines, intermediates, and their use as pesticides
Compounds of formula whereinA is an unsubstituted or substituted aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical wherein a ring nitrogen atom may have been replaced by a group...
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6642221 |
Vanadium compounds as anti-proliferative agents
Vanadium compounds as anti-proliferative agents. These compounds act to disrupt mitotic and meiotic spindle formation and thus are useful to prevent cell mitosis (proliferation) and meiosis.
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6627665 |
Non-dusting copper pyrithione dispersion
The present invention is directed to a non-dusting copper pyrithione dispersion, comprising an admixture of: from about 20 to about 99 wt % of copper pyrithione; from about 0.05 to about 30 wt % of...
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6608050 |
Lyophilizate of lipid complex of water insoluble porphyrins
The present invention relates to a pharmaceutically acceptable dosage form of water insoluble porphyrins, particularly metal containing porphyrins such as tin porphyrin, which can be complexed with...
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6579866 |
Composition and method for modulating nutrient partitioning
A nutritional supplement composition for modulating nutrient partitioning in a human so as to increase oxidation of fat and promote increased storage of glycogen is composed of hydroxycitric acid,...
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6558666 |
Chromium-containing carbohydrase enzyme food supplement composition
A chromium(III)-containing carbohydrase enzyme food supplement composition providing at least one cellulase fungal enzyme, at least one alpha amylase fungal enzyme, at least one hemicellulase...
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6528502 |
Composition and method for improved carbohydrate management in mammals
A nutritional supplement for use in managing carbohydrates and enhancing anabolism in mammals is described. The nutritional supplement contains regulated amounts of niacin, chromium, and vanadium,...
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6471998 |
Chromium picolinate compositions
Compositions comprising chromic tripicolinate or chromic polynicotinate in the form of enteric-coated tablets, capsules or microbeads, optionally in combination with nicotinic acid, picolinic acid...
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