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9034862 Compositions and methods for the treatment of cancer  
The present invention relates to compositions, kits, and methods for treatment of cancers. In some cases, the composition comprises a platinum compound comprising a phenanthridine ligand.
9023402 Method for treating a mammal by administration of a compound having the ability to release CO  
Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases...
9011933 Therapeutic methods and pharmaceutical compositions for treating warts with tellurium compounds  
A novel method for treating skin and mucosal membrane ailments caused by human papilloma viruses, which utilizes tellurium-containing compounds, is disclosed. Also disclosed are pharmaceutical...
8968715 Drug delivery systems for photodynamic therapy  
The invention is generally related to the field of photodynamic therapy by use of photosensitizers and stabilized formulations of the photosensitizers. These formulations may be used to deliver a...
8951969 Compositions and methods for treating centrally mediated nausea and vomiting  
Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
8946202 Substituted porphyrins  
The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby...
8940723 Combination of a pyrroloquinoline compound and a beta-lactam antimicrobial agent, mupirocin or chlorhexidine  
This invention relates to the use of 4-methyl-8-phenoxy-1-(2-phenylethyl)-2,3-dihydro-1H-pyrrolo[ 3,2-c]quinoline or a pharmaceutically acceptable derivative thereof in combination with another...
8906897 Antimicrobial agents based on hemin derivatives  
The invention relates to novel antimicrobial, including antibacterial and antifungal, agents and compositions based on hemin derivatives of general formula (I), and also to the production of novel...
8906896 Platinum acridine anti-cancer compounds and methods thereof  
Acridine containing cisplatin compounds are disclosed that show greater efficacy than other cisplatin compounds for treating cancer. The compounds are compounds of Formula I wherein the variables...
8877715 Cytotoxic conjugates having neuropeptide Y receptor binding compound  
There is provided a series of novel neuropeptide Y-cytotoxic conjugates, compositions comprising the same, and methods relating to their therapeutic use for the treatment of disease or condition...
8859533 Metalloinsertor complexes targeted to DNA mismatches  
A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the...
8853128 Turfgrass fungicide formulation with pigment  
Oil-in-water fungicidal formulations are prepared having pigment dispersed therein, the pigment being stable within the oil-in-water emulsion as a result of the addition of suitable silicone...
8835416 High-purity large-scale preparation of stannsoporfin  
Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
8791099 Transition metal complexes of corroles for preventing cardiovascular diseases or disorders  
Transition metal complexes of amphiphilic/bipolar corroles, optically active isomers or pharmaceutically acceptable salts thereof are useful for prevention of a cardiovascular disease or disorder...
8771682 Methods and compositions for reducing interleukin-4 or interleukin-13 signaling  
The present invention relates generally to methods and compositions for reducing Interleukin-4 or Interleukin-13 signaling, in particular to treat asthma and atopic dermatitis. The inventors have...
8765729 Cancer therapy  
The present invention relates, in general, to cancer therapy, and, in particular, to a method of preventing or treating cancer using low molecular weight antioxidants (e.g., mimetics of superoxide...
8709460 Chemical method of making a suspension, emulsion or dispersion of pyrithione particles  
A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated...
8709449 Methods and compositions for improving photodynamic therapy through administration of lipids  
The present invention provides methods and compositions for increasing the effectiveness of photodynamic therapy (“PDT”) and for reducing the duration of skin phototoxicity associated with PDT...
8673274 Composition comprising pyrithione or a polyvalent metal salt of a pyrithione and furametpyr  
The present invention relates to a composition comprising an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione, an effective amount of furametpyr and an effective amount...
RE44704 Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents  
The present invention is based on the discovery that the administration of at least one immunoconjugate and at least one chemotherapeutic agent provides an unexpectedly superior treatment for...
8623826 Compositions and methods for treating centrally mediated nausea and vomiting  
Provided are methods for treating nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery, comprising the co-administration of netupitant, palonosetron and dexamethasone.
8618088 Methods of inhibiting choroidal neovascularization  
The present invention relates to compositions and methods for inhibiting unwanted angiogenesis, particularly those of ocular tissues. The treatment, inhibition, and/or prevention of choroidal...
8618089 Substituted porphyrins  
Substituted metalloporphyrin compounds are described, along with pharmaceutical compositions containing the same, and methods of use thereof in protecting cells from oxidant-induced toxicity and...
8603814 Method of inhibiting nonsense-mediated mRNA decay  
Provided are methods for treating a NAD comprising administering to a patient suffering from a NAD a composition comprising an eIF5A inhibitor compound in an amount effective to prevent...
8592404 Derivatives of porphyrin, particularly chlorins and/or bacteriochlorins, and uses thereof in photodynamic therapy  
The invention relates to derivatives of porphyrin, particularly chlorins and/or bacteriochlorins, which can be used in photodynamic therapy. According to the formulas of the invention, X1, X2, X3,...
8569210 Turfgrass fungicide formulation with pigment  
Oil-in-water fungicidal formulations are prepared having pigment dispersed therein, the pigment being stable within the oil-in-water emulsion as a result of the addition of suitable silicone...
8551456 Combination therapy and methods for treating bacterial biofilms  
A combination therapy for treating a bacterial biofilm comprises a therapeutically effective amount of an antibiotic comprising an aminoglycoside or tetracycline, or a combination of two or more...
8530459 Swallowtail motifs for imparting water solubility to porphyrinic compounds  
Porphyrinic compounds that contain solubilizing groups are described, along with methods of making and using the same and compositions comprising such compounds. Examples of such compounds include...
8530458 High-purity large-scale preparation of stannsoporfin  
Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
8524214 Polyal drug conjugates comprising variable rate-releasing linkers  
Polyal-Drug conjugates comprising a variable rate-releasing linker are described along with methods of making such conjugates. Uses for such Polyal-Drug conjugates is also described.
8518930 Therapeutic combination comprising a CDKS inhibitor and an antineoplastic agent  
The present invention provides a therapeutic combination comprising (a) a compound of formula (I) as set forth in the specification and (b) one or more antineoplastic agents selected from the...
8470808 Oxidant scavengers for treatment of type I diabetes or type II diabetes  
The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method...
8461142 Water-soluble anionic bacteriochlorophyll derivatives and their uses  
The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one, preferably two or three, negatively charged groups and/or...
8455440 Combination anticoagulant therapy with a compound that acts as a factor Xa inhibitor  
The present invention is directed to methods of using combination therapies containing [2-({4-[(dimethylamino)iminomethyl]phenyl}carbonylamino)-5-m ethoxyphenyl]-N-(5-chloro(2-pyridyl))carboxamide...
8450359 Polymer-supported photosensitizers for the generation of singlet oxygen  
A material comprising at least one polymer and at least one sensitizer wherein the sensitizer is localised at a surface of the material wherein the sensitizer is an agent or compound able to...
8398759 Environmental friendly anti-microbial adhesion agents for anti-fouling paints and anti-fouling paints containing them  
An ecologically compatible anti-microbial-adhesion agent is described, which is particularly suitable for use in anti-fouling paints, preferably for boats, characterized in that it comprises a...
8357678 Chair ruthenium complexes and their use as anticancer agents  
The invention is reported a type of chair ruthenium complexes and their used as anticancer agent. The general formulae of these chair ruthenium complexes is: A-[Ru(bpy)2L](PF6)2, where in A is Δ...
8268810 Lipophilic chelates and their use in imaging  
The invention relates to chelate compounds which can be used in MRI, the chelates being intended to be conveyed by lipophilic transporters, such as lipid nanoparticles or liposomes. The invention...
8252780 Organometallic complexes as therapeutic agents  
This invention comprises salophene-based metallic complexes. Included are metal-chelating analogues, and method of their preparation and use. These analogues have therapeutic activity including...
8247399 Photoactive metal nitrosyls for blood pressure regulation and cancer therapy  
Disclosed are nitric oxide delivery agents and methods of their use, more specifically to photoactive compounds, which are able to perform targeted delivery of nitric oxide in vitro and in vivo...
8232267 Porphyrin catalysts and methods of use thereof  
This invention provides a novel class of substituted macrocyclic porphyrin compounds. The compounds are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of...
8222242 Nitric oxide releasing compounds  
Compositions comprising nitrosyl-cobinamide are provided. Also provided are methods for treating hypertension, which comprise administering therapeutically effective amounts of...
8217026 Substituted porphyrins  
The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby...
8211883 Topical delivery of phthalocyanines  
The invention relates to topical pharmaceutical compositions comprising a phthalocyanine, wherein a diamagnetic metal ion moiety is either coordinated or covalently bound to the phthalocyanine...
8207154 Catatonic bacteriochlorophyll derivatives  
The invention provides cationic tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one positively charged group and/or at least one basic group that is...
8193175 Ruthenium complexes for treating cancers  
The invention concerns uses or methods for treating proliferative pathologies, in particular cancers, using ruthenium compounds and compositions containing the same. The invention also concerns...
8187825 Thiol detection method  
It is an object of the present invention to provide: a novel thiol-detecting reagent, which can be used in vivo and which solves the problem regarding the generation of background fluorescence due...
8173630 Multipodal tethers for high-density attachment of redox-active moieties to substrates  
This invention provides redox-active molecules attached to polypodal (e.g., bipodal, tripodal, quadrapodal, pentapodal, etc.) tethers that can be used for attachment of the redox-active molecules...
8163726 Method of inhibiting choroidal neovascularization  
The present invention relates to compositions and methods for inhibiting unwanted angiogenesis, particularly those of ocular tissues. The treatment, inhibition, and/or prevention of choroidal...
8158615 Anti-viral composition for the topical treatment of Herpes Labialis (cold sores) and method for use thereof  
A composition for the treatment of Herpes Labialis which contains CTC-96 as the active ingredient is disclosed. Methods for using the composition are also disclosed. The composition may be used as...

Matches 1 - 50 out of 401 1 2 3 4 5 6 7 8 9 >