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8828451 Akt sensitization of cancer cells  
Most human tumors find ways to resist anticancer drug monotherapy. Akt is considered a likely peptide providing such monotherapy drug resistance. Data indicates that Akt chemoresistance is induced...
8765729 Cancer therapy  
The present invention relates, in general, to cancer therapy, and, in particular, to a method of preventing or treating cancer using low molecular weight antioxidants (e.g., mimetics of superoxide...
8759331 X-ray and gamma-photon activable organic compounds, their preparation and their uses  
The present invention relates to a X-ray and gamma-photon activable compound responding to the following formula (I). The present invention also relates to methods of synthesizing a compound...
8753673 Liposome composition for delivery of a therapeutic agent to eyes  
The invention provides a liposome composition for delivering high pay-load of a therapeutic agent to neovascularization sites of the eyes in a patient in need thereof. The liposome composition for...
8722578 Spiroheterocyclic pyrrolidinedione herbicidal compositions  
Herbicidal compositions containing as active ingredients spiroheterocyclic pyrrolidine dione compounds.
8703208 Nanometer mesoporous silica-based xerogel styptic process and its preparing process and application  
The invention disclosed a novel mesoporous silica-based xerogel and its use in hemorrhage control. The mesoporous silica-based xerogel material has tunable mesopores (1-50 nm), high specific...
8697681 Method for prediction of therapeutic effect of chemotherapy employing expression level of dihydropyrimidine dehydrogenase gene as measure  
The present invention provides an antitumor agent comprising cisplatin and a combination drug of tegafur/gimeracil/oteracil potassium that ensures an excellent life-prolongation effect in advanced...
8691726 Synergistic combination of a glyphosate compound and ZPT  
A synergistic antimicrobial composition containing a glyphosate compound and zinc pyrithione is provided. Also provided is a method of inhibiting the growth of or controlling the growth of...
8648064 Metal complexes of N-heterocyclic carbenes  
The present invention generally relates to metal complexes of N-heterocyclic carbenes that contain one or more additional active moieties and/or groups therein. In one embodiment, the present...
8629100 Method of inhibiting clostridium difficile by administration of oritavancin  
Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and...
8598207 Compositions containing opioid antagonists  
Compositions containing opioid antagonists, particularly alvimopan and its active metabolite, with improved solubility and bioavailability for oral or parenteral administration, injectable dosage...
8592392 Multiple antioxidant micronutrients  
A method for optimizing the health of humans according to their age and sex is disclosed wherein the method comprises administering to said humans a daily dose of a multiple antioxidant...
8569210 Turfgrass fungicide formulation with pigment  
Oil-in-water fungicidal formulations are prepared having pigment dispersed therein, the pigment being stable within the oil-in-water emulsion as a result of the addition of suitable silicone...
8563472 Synergistic fungicidal and algicidal compositions including 2-hydroxyphenylaldehyde and 2-hydroxyphenylketone heterocycloyhydrazones and copper  
The present invention relates to the use of mixtures containing 2-hydroxyphenylaldehyde and 2-hydroxyphenylketone heterocycloylhydrazone compounds and copper for controlling the growth of fungi and...
8549768 Methods for freeze drying  
A method for producing a fog of ice nuclei by introducing a cryogenic fluid and a humid gas stream into a freeze dryer. The cryogenic fluid and humid gas stream will form ice nuclei having a...
8545813 Pre-templated macromolecular architectures with multiple Gd(III) complexes and methods of use as MRI contrast agents  
The present invention relates to contrast agents for MRI and related methods of use.
8536208 Antifungal composition  
A pharmaceutical composition for oral administration which is self-emulsifying on contact with an aqueous phase, in particular gastrointestinal fluids, and which comprises: (a) an antifungally...
8518930 Therapeutic combination comprising a CDKS inhibitor and an antineoplastic agent  
The present invention provides a therapeutic combination comprising (a) a compound of formula (I) as set forth in the specification and (b) one or more antineoplastic agents selected from the group...
8518873 Method of inhibiting clostridium difficile by administration of oritavancin  
Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and...
8506990 Local administration of gallium compositions to treat pain  
Provided are methods of treating pain, including neuropathic pain, in human and veterinary individuals. These methods employ locally administrable pharmaceutical gallium compositions, including...
8481522 Platinum-N-heterocyclic carbene derivatives, preparation thereof and therapeutic use thereof  
The invention relates to the platinum N-heterocycle derivatives of general formula (I) in which—R1 and/or R2 are, independently of one another, an aryl or aralkyl group, each optionally s...
8460939 Method for producing purified hematinic iron-saccharidic complex and product produced  
A method for separating and purifying the active hematinic species (AHS) present in iron-saccharidic compositions, including AHS such as sodium ferric gluconate complex, ferric hydroxide-sucrose...
8455543 Platinum complexes and methods for inhibiting tumor cell proliferation  
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to...
8445475 Supramolecular complexes as photoactivated DNA cleavage agents  
The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal...
8383673 Nitridoosmium(VI) complexes for treatment of cancer  
The invention relates to nitridoosmium complexes and methods of using these compounds as treatments for cancer.
8324197 Transplatinum complexes with N2O2 donor sets as cytotoxic and antitumor agents  
Trans-platinum compounds comprising carboxylato groups are disclosed, with anti-cancer usefulness. The carboxylato groups participate in solubilizing trans-platinum compounds to which they are...
8317912 Wet state preservation of mineral slurries  
The present invention relates to an antimicrobial composition comprising an isothiazolin-3-one, such as 1,2-benzisothiazolin-3-one, a zinc compound selected from zinc salts, zinc oxide, zinc...
8293268 Local administration of gallium compositions to treat pain  
Provided are methods of treating pain, including neuropathic pain, in human and veterinary individuals. These methods employ locally administrable pharmaceutical gallium compositions, including...
8263642 Antimicrobial compounds and methods of use thereof  
In one aspect, the invention relates to compounds and methods useful for activating heme sensor systems; for decreasing virulence of bacteria, for example, Staphylococcus aureus; pharmaceutical...
8247398 Zinc complexes of natural amino acids for treating elevated copper caused toxicities  
The present invention relates to the use of zinc complexes of natural amino acids, especially L-arginine, L-lysine, L-ornithine, and other natural amino acids, in a molar ratio of about 1:2...
8236788 Azolylmethyloxiranes, use thereof for controlling plant pathogenic fungi, and agents containing the same  
The present invention relates to azolylmethyloxiranes of the general formula I in whichA or B is phenyl which is substituted by one CN and optionally by one to three of the following substituents:...
8236787 Frequency modulated drug delivery (FMDD)  
Embodiments of the present disclosure include a coordination complex, comprising a first biologically active moiety, a second biologically active moiety, and a metal, wherein the first biologically...
8221799 Multiple antioxidant optimal health/veterans ultimate complete formulations  
The invention is directed to a method for administering antioxidant micronutrient formulations comprising multiple dietary and endogenous antioxidants, B-vitamins, vitamin D and minerals at...
8216971 Pesticide composition comprising propamocarb-hydrochloride and an insecticide active substance  
The present invention relates to a pesticide composition intended for protecting plants, crops or seeds against phyto-pathogenic fungi or damaging insects, and the corresponding methods of...
8211401 Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof for inhibiting PSMA  
A compound of Formula I, a pharmaceutically acceptable salt, or solvate thereof: complexes with metals such as rhenium, technetium, and others to provide a complex for imaging tissues or treating...
8211402 CA-IX specific radiopharmaceuticals for the treatment and imaging of cancer  
A compound that recognizes and binds to the CA-IX protein has Formula I, II, III, or IV. The compounds may include a radioactive element for radioimaging or therapeutic applications. Thus,...
8153558 Method of improving grass quality  
The invention relates to a method of improving grass quality comprising applying an effective amount of a composition containing a phthalocyanine to the grass in the substantial absence of...
8071581 Triazolopyridazine protein kinase modulators  
The present disclosure relates to triazolopyridazine protein kinase modulators of Formula (I), methods of using these compounds to treat diseases mediated by kinase activity.
8067405 Superoxide dismutase mimics for the treatment of ocular disorders and diseases  
The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
8062677 Methods and compositions for the sustained release of chromium  
Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the...
8043422 Combinations of phenylpyrroles and pyrion compounds  
The present invention relates to combinations of a phenylpyrrole, or a salt thereof, and a pyrion compound which provide an improved biocidal effect. More particularly, the present invention...
8007921 Gypsum board containing antimicrobial and antibacterial compounds  
A novel gypsum board having improved antimicrobial and antibacterial properties is disclosed. The board comprises a gypsum core, front and back paper facings, and a polymeric antimicrobial or...
8003635 Superoxide dismutase mimics for the treatment of ocular disorders and diseases  
The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
7989440 Metal coordinated compositions  
A metal coordination complex of a biologically active moiety and a metal is disclosed. The complex confers to the biologically active moiety an improved performance which can include potency,...
7977381 Platinum complexes and methods for inhibiting tumor cell proliferation  
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to...
7951792 Antimicrobial composition useful for preserving wood  
Antimicrobial compositions useful for preserving wood, and comprising a variety of antimicrobial compounds.
7947672 Water-soluble anionic bacteriochlorophyll derivatives and their uses  
The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one, preferably two or three, negatively charged groups and/or...
7947673 Method of scintigraphy  
The invention relates to combination comprising a pharmaceutically acceptable preparation of a compound of formula (I), or a pharmaceutically acceptable salt thereof, and a gallium and its use in...
7888311 Uranium-chelating peptides and uses thereof  
The invention concerns uranium-chelating peptides as well as their uses for decontaminating soils and water, and for detecting and treating people contaminated by uranium. Said peptides have a...
RE42152 Aromatic-linked polyamine macrocyclic compounds with anti-HIV activity  
Polyamine macrocyclic compounds, e.g. of 10 to 15 ring members and 3 to 6 ring amine nitrogens, linked through methylene groups to an aromatic moiety, show high selective activity against HIV.