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8445475 |
Supramolecular complexes as photoactivated DNA cleavage agents
The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal...
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8383673 |
Nitridoosmium(VI) complexes for treatment of cancer
The invention relates to nitridoosmium complexes and methods of using these compounds as treatments for cancer.
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8324197 |
Transplatinum complexes with N2O2 donor sets as cytotoxic and antitumor agents
Trans-platinum compounds comprising carboxylato groups are disclosed, with anti-cancer usefulness. The carboxylato groups participate in solubilizing trans-platinum compounds to which they are...
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8317912 |
Wet state preservation of mineral slurries
The present invention relates to an antimicrobial composition comprising an isothiazolin-3-one, such as 1,2-benzisothiazolin-3-one, a zinc compound selected from zinc salts, zinc oxide, zinc...
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8293268 |
Local administration of gallium compositions to treat pain
Provided are methods of treating pain, including neuropathic pain, in human and veterinary individuals. These methods employ locally administrable pharmaceutical gallium compositions, including...
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8263642 |
Antimicrobial compounds and methods of use thereof
In one aspect, the invention relates to compounds and methods useful for activating heme sensor systems; for decreasing virulence of bacteria, for example, Staphylococcus aureus; pharmaceutical...
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8247398 |
Zinc complexes of natural amino acids for treating elevated copper caused toxicities
The present invention relates to the use of zinc complexes of natural amino acids, especially L-arginine, L-lysine, L-ornithine, and other natural amino acids, in a molar ratio of about 1:2...
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8236788 |
Azolylmethyloxiranes, use thereof for controlling plant pathogenic fungi, and agents containing the same
The present invention relates to azolylmethyloxiranes of the general formula I in whichA or B is phenyl which is substituted by one CN and optionally by one to three of the following substituents:...
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8236787 |
Frequency modulated drug delivery (FMDD)
Embodiments of the present disclosure include a coordination complex, comprising a first biologically active moiety, a second biologically active moiety, and a metal, wherein the first biologically...
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8221799 |
Multiple antioxidant optimal health/veterans ultimate complete formulations
The invention is directed to a method for administering antioxidant micronutrient formulations comprising multiple dietary and endogenous antioxidants, B-vitamins, vitamin D and minerals at...
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8216971 |
Pesticide composition comprising propamocarb-hydrochloride and an insecticide active substance
The present invention relates to a pesticide composition intended for protecting plants, crops or seeds against phyto-pathogenic fungi or damaging insects, and the corresponding methods of...
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8211401 |
Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof for inhibiting PSMA
A compound of Formula I, a pharmaceutically acceptable salt, or solvate thereof: complexes with metals such as rhenium, technetium, and others to provide a complex for imaging tissues or treating...
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8211402 |
CA-IX specific radiopharmaceuticals for the treatment and imaging of cancer
A compound that recognizes and binds to the CA-IX protein has Formula I, II, III, or IV. The compounds may include a radioactive element for radioimaging or therapeutic applications. Thus,...
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8153558 |
Method of improving grass quality
The invention relates to a method of improving grass quality comprising applying an effective amount of a composition containing a phthalocyanine to the grass in the substantial absence of...
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8071581 |
Triazolopyridazine protein kinase modulators
The present disclosure relates to triazolopyridazine protein kinase modulators of Formula (I), methods of using these compounds to treat diseases mediated by kinase activity.
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8067405 |
Superoxide dismutase mimics for the treatment of ocular disorders and diseases
The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
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8062677 |
Methods and compositions for the sustained release of chromium
Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the...
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8043422 |
Combinations of phenylpyrroles and pyrion compounds
The present invention relates to combinations of a phenylpyrrole, or a salt thereof, and a pyrion compound which provide an improved biocidal effect. More particularly, the present invention...
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8007921 |
Gypsum board containing antimicrobial and antibacterial compounds
A novel gypsum board having improved antimicrobial and antibacterial properties is disclosed. The board comprises a gypsum core, front and back paper facings, and a polymeric antimicrobial or...
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8003635 |
Superoxide dismutase mimics for the treatment of ocular disorders and diseases
The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
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7989440 |
Metal coordinated compositions
A metal coordination complex of a biologically active moiety and a metal is disclosed. The complex confers to the biologically active moiety an improved performance which can include potency,...
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7977381 |
Platinum complexes and methods for inhibiting tumor cell proliferation
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to...
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7951792 |
Antimicrobial composition useful for preserving wood
Antimicrobial compositions useful for preserving wood, and comprising a variety of antimicrobial compounds.
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7947672 |
Water-soluble anionic bacteriochlorophyll derivatives and their uses
The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one, preferably two or three, negatively charged groups and/or...
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7947673 |
Method of scintigraphy
The invention relates to combination comprising a pharmaceutically acceptable preparation of a compound of formula (I), or a pharmaceutically acceptable salt thereof, and a gallium and its use in...
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7888311 |
Uranium-chelating peptides and uses thereof
The invention concerns uranium-chelating peptides as well as their uses for decontaminating soils and water, and for detecting and treating people contaminated by uranium. Said peptides have a...
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RE42152 |
Aromatic-linked polyamine macrocyclic compounds with anti-HIV activity
Polyamine macrocyclic compounds, e.g. of 10 to 15 ring members and 3 to 6 ring amine nitrogens, linked through methylene groups to an aromatic moiety, show high selective activity against HIV.
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7883897 |
Method for producing purified hematinic iron-saccharadic complex and product produced
A method for separating and purifying the active hematinic species (AHS) present in iron-saccharidic compositions, including AHS such as sodium ferric gluconate complex, ferric hydroxide-sucrose...
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7863264 |
Stabilised compositions having antibacterial activity
A stabilised composition having antibacterial, antiviral and/or antifungal activity, said composition comprising silver ions and a ligand, characterised in that the composition comprises a complex...
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7855180 |
Structure and method for releasing substance therefrom
A structure comprises at least a porous body holding a substance releasably, comprising a capping member for keeping the substance inside the pore and/or on at least a part of the entire surface of...
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7811609 |
Use of metal compounds to treat gastrointestinal infections
Cobalt salts have been found to be particularly effective against H. pylori and may therefore be used to treat gastrointenstinal infection with this bacteria. The cobalt salts have the advantage of...
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7807662 |
Platinum IV complex inhibitor
The invention disclosed herein provides methods for diagnosing and treating diseases and/or conditions associated with dysregulated Stat3-mediated activity.
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7776833 |
Use of cyclic bioisosters of purine system derivatives for treating diseases produced by disorders of niterergic and dopaminergic systems
The invention relates to application of compounds having a general structural formula: where R= Li, Na, K, R1=—H, —NH2, —Br, —Cl, —OH, —COOH,B=—N═, —CH═, Z=—CH═, —N═,A=—N═ at B=—N═, Z=—...
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7759333 |
Superoxide dismutase mimics for the treatment of ocular disorders and diseases
The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
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7754706 |
Superoxide dismutase mimics for the treatment of ocular disorders and diseases
The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
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7745482 |
Alpha crystalline form of strontium ranelate
Alpha crystalline form of strontium ranelate of formula (I): characterised by its powder X-ray diffraction diagram and by a water content of from 22 to 24%. Medicinal products containing the same...
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7700626 |
Compositions containing opioid antagonists
Compositions containing opioid antagonists, particularly alvimopan and its active metabolite, with improved solubility and bioavailability for oral or parenteral administration, injectable dosage...
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7687273 |
Method for producing purified hematinic iron-saccharidic complex and product produced
A method for separating and purifying the active hematinic species (AHS) present in iron-saccharidic compositions, including AHS such as sodium ferric gluconate complex, ferric hydroxide-sucrose...
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7670416 |
Use of a combination of substances to prevent biofouling organisms
A combination of selected substances in paint to prevent the settlement and growth of different bio-fouling organisms with a reduced negative effect on the ecosystems compared to present methods....
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7648977 |
Pharmaceutical composition having a ruthenium oxalato compound and method of using the same
The present invention relates to a pharmaceutical composition comprising one or more of the following ruthenium oxalato compounds I, II, III and IV as an active ingredient. The pharmaceutical...
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7612057 |
Supramolecular complexes as photoactivated DNA cleavage agents
The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal...
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7605145 |
Micronutrient formulations for treatment of diabetes mellitus
Formulations for minimizing damage to at least one of cells, organs and systems within the body of a subject afflicted with Diabetes Mellitus. The invention additionally encompasses methods for...
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7582418 |
Antimicrobial chelates
Methods useful for inhibiting growth of a variety of microbes including bacteria and fungi are disclosed. The methods involve contacting a microbe with an inhibitory amount of a zinc chelate....
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7563565 |
Method of preparing bio-identical hormones
The embodied composition is a dose of bio-identical hormones in a solvent with a vasodilator, a hormone modulator, and a carrier for balancing and maintaining Cortisol level in a human. The dose...
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7462369 |
Anti-viral compositions and methods of making and using the anti-viral compositions
Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed...
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7449451 |
Use of multiple antioxidant micronutrients as systemic biological radioprotective agents against potential ionizing radiation risks
Disclosed herein is a method for protecting humans in need of such protection from physical damage caused by ionizing radiation comprising administering to said humans on a defined basis prior to...
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7445799 |
Compositions for microbial and chemical protection
An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and...
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7416736 |
Antimicrobial compositions
This invention concerns antimicrobial compositions that are useful for industrial applications. More specifically, it concerns antimicrobial compositions that, by combining...
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7410655 |
Anticancer agent
An anticancer agent containing platinum preparation, humic substances, water and sodium chloride. Potassium tetrachloroplatinate is used as a platinum compound and lignohumic acid ammonium salts...
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7399755 |
Formulations comprising multiple dietary and endogenously made antioxidants and B-vitamins and use of same
The invention is directed to formulations comprised of multiple dietary and endogenously made antioxidants and B-vitamins and the use of these formulations in preventing and treating coronary...
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